keyword
https://read.qxmd.com/read/33838522/a-systematic-review-and-meta-analysis-of-propofol-versus-midazolam-sedation-in-adult-intensive-care-icu-patients
#1
REVIEW
Raphaela Garcia, Jorge I F Salluh, Teresa Raquel Andrade, Daniela Farah, Paulo S L da Silva, Danielle F Bastos, Marcelo C M Fonseca
PURPOSE: Compare outcomes of adult patients admitted to ICU- length of ICU stay, length of mechanical ventilation (MV), and time until extubation- according to the use of propofol versus midazolam. METHODS: We searched MEDLINE, EMBASE, LILACS, and Cochrane databases to retrieve RCTs that compared propofol and midazolam used as sedatives in adult ICU patients. We applied a random-effects, meta-analytic model in all calculations. We applied the Cochrane collaboration tool and GRADE...
April 6, 2021: Journal of Critical Care
https://read.qxmd.com/read/33838482/necrotising-fasciitis-of-the-posterior-neck-crossing-the-midline-a-case-report
#2
Talisa Ross, Vikas Acharya, Arran Patel, Taran Tatla
INTRODUCTION AND IMPORTANCE: Craniofacial necrotising fasciitis is a complex condition, with high mortality given its propensity to descend via the deep neck spaces into the chest and mediastinum. Management requires optimal antimicrobial therapy with associated aggressive surgical debridement. PRESENTATION OF CASE: A 64-year-old man presented to ENT with a posterior neck swelling. Despite incision and drainage of the swelling following a trial of antimicrobial therapy, it increased in size, with areas of overlying necrosis demonstrated...
April 1, 2021: International Journal of Surgery Case Reports
https://read.qxmd.com/read/33838408/injury-severity-arrival-physiology-coagulopathy-and-outcomes-among-the-youngest-trauma-patients
#3
Vikas S Gupta, Ioannis N Liras, Myron Allukian, Bryan A Cotton, Charles S Cox, Matthew T Harting
BACKGROUND: Although physiologic differences exist between younger and older children, pediatric trauma analyses are weighted toward older patients. Trauma-induced coagulopathy, determined by rapid thrombelastography (rTEG), is a predictor of outcome in trauma patients, but the significance of rTEG values among very young trauma patients remains unknown. Our objective was to identify the prehospital or physiologic factors, including rTEG values, that were associated with mortality in trauma patients younger than 5 y old...
April 7, 2021: Journal of Surgical Research
https://read.qxmd.com/read/33838406/early-outcomes-of-surgical-stabilisation-of-traumatic-rib-fractures-single-center-review-with-a-real-world-evidence-perspective
#4
Negin Sedaghat, Corinna Chiong, Richard Tjahjono, Jeremy Hsu
BACKGROUND: Randomized controlled trials have demonstrated that surgical stabilization of rib fractures (SSRF) in selected trauma patients is associated with potential benefits. This study evaluates the real-world outcomes of SSRF since its implementation at Westmead Hospital, Australia. We hypothesize these outcomes to be similar to that reported by best-evidence in the literature. MATERIALS AND METHODS: A retrospective analysis of data on all consecutive SSRF performed between January 2013 to December 2018 was completed...
April 7, 2021: Journal of Surgical Research
https://read.qxmd.com/read/33838405/effect-of-nimodipine-and-botulinum-toxin-a-on-peripheral-nerve-regeneration-in-rats-a-pilot-study
#5
Scott K Odorico, Nikita O Shulzhenko, Weifeng Zeng, Aaron M Dingle, David O Francis, Samuel O Poore
BACKGROUND: Peripheral nerve damage is a frequent problem, with an estimated 2.8%-5.0% of trauma admissions involving peripheral nerve injury. End-to-end, tension-free microsurgical repair (neurorrhaphy) is the current gold standard treatment for complete transection (neurotmesis). While neurorrhaphy reapproximates the nerve, it does not address the complex molecular regenerative process. Evidence suggests that botulinum toxin A (BTX) and nimodipine (NDP) may improve functional recovery, but mechanisms of action remain unknown...
April 7, 2021: Journal of Surgical Research
https://read.qxmd.com/read/33838403/utility-of-the-marshall-rotterdam-classification-scores-in-predicting-outcomes-in-trauma-patients
#6
Adel Elkbuli, Saamia Shaikh, Kelly McKenney, Hunter Shanahan, Mark McKenney, Kimberly McKenney
BACKGROUND: Traumatic Brain Injury (TBI) is a leading cause of mortality in the trauma population. Accurate prognosis remains a challenge. Two common Computed Tomography (CT)-based prognostic models include the Marshall Classification and the Rotterdam CT Score. This study aims to determine the utility of the Marshall and Rotterdam scores in predicting mortality for adult patients in coma with severe TBI. METHOD: Retrospective review of our Level 1 Trauma Center's registry for patients ≥ 18 years of age with blunt TBI and a Glasgow Coma Scale (GCS) of 3-5, with no other significant injuries...
April 7, 2021: Journal of Surgical Research
https://read.qxmd.com/read/33838091/bone-density-and-bone-health-alteration-in-boys-with-duchenne-muscular-dystrophy-a-prospective-observational-study
#7
Renu Suthar, B V Chaithanya Reddy, Manisha Malviya, Titiksha Sirari, Savita Verma Attri, Ajay Patial, Minni Tageja, Gunjan Didwal, Niranjan K Khandelwal, Arushi G Saini, Lokesh Saini, Jitendra K Sahu, Devi Dayal, Naveen Sankhyan
OBJECTIVES: Boys with Duchenne Muscular Dystrophy (DMD) are at increased risk for compromised bone health, manifesting as low-impact trauma long bone fractures and vertebral compression fractures. METHODS: In a prospective observational study, we studied bone health parameters in North Indian boys with DMD. We consecutively enrolled ambulatory boys with DMD on glucocorticoid therapy. Bone health was evaluated with X-ray spine, Dual-energy X-ray absorptiometry (DXA), serum calcium, vitamin D3 (25[OH]D), 1,25-dihyroxyvitamin D3 (1,25[OH]2 D3 ), serum osteocalcin, osteopontin, and N terminal telopeptide of type 1 collagen (Ntx) levels...
April 12, 2021: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://read.qxmd.com/read/33838081/dental-trauma-in-toddlers-1-3-years-of-age-living-in-multicultural-areas-of-stockholm-sweden-a-retrospective-cohort-study
#8
Maria Anderson, Demet Duran Sahin, Georgios Tsilingaridis
BACKGROUND/AIM: Traumatic dental injuries are common and affect many children. The aim of this retrospective study was to investigate the prevalence and characteristics of dental trauma as well as the costs and resource use in a cohort of children aged 1-3 years in low socioeconomic areas (low income and educational level) of Stockholm. MATERIALS AND METHODS: Data were extracted from a larger intervention trial and analyzed for the prevalence and other characteristics of dental trauma as well as patient characteristics of children (n = 1346) from six dental clinics in low-income, multicultural areas...
April 10, 2021: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://read.qxmd.com/read/33838007/-i-just-keep-quiet-about-it-and-act-as-if-everything-is-alright-the-cascade-from-trauma-to-disengagement-among-adolescents-living-with-hiv-in-western-kenya
#9
Leslie A Enane, Edith Apondi, Mark Omollo, Judith J Toromo, Salim Bakari, Josephine Aluoch, Clemette Morris, Rami Kantor, Paula Braitstein, J Dennis Fortenberry, Winstone M Nyandiko, Kara Wools-Kaloustian, Batya Elul, Rachel C Vreeman
INTRODUCTION: There are approximately 1.7 million adolescents living with HIV (ALHIV, ages 10 to 19) globally, including 110,000 in Kenya. While ALHIV experience poor retention in care, limited data exist on factors underlying disengagement. We investigated the burden of trauma among disengaged ALHIV in western Kenya, and its potential role in HIV care disengagement. METHODS: We performed in-depth qualitative interviews with ALHIV who had disengaged from care at two sites, their caregivers and healthcare workers (HCW) at 10 sites, from 2018 to 2020...
April 2021: Journal of the International AIDS Society
https://read.qxmd.com/read/33837949/laparoscopic-splenectomy-as-a-definitive-management-option-for-high-grade-traumatic-splenic-injury-when-non-operative-management-is-not-feasible-or-failed-a-5-year-experience-from-a-level-one-trauma-center-with-minimally-invasive-surgery-expertise
#10
Arianna Birindelli, Matthew Martin, Mansoor Khan, Gaetano Gallo, Edoardo Segalini, Alice Gori, Amy Yetasook, Mauro Podda, Antonio Giuliani, Gregorio Tugnoli, Robert Lim, Salomone Di Saverio
Technique, indications and outcomes of laparoscopic splenectomy in stable trauma patients have not been well described yet. All hemodynamically non-compromised abdominal trauma patients who underwent splenectomy from 1/2013 to 12/2017 at our Level 1 trauma center were included. Demographic and clinical data were collected and analysed with per-protocol and an intention-to-treat comparison between open vs laparoscopic groups. 49 splenectomies were performed (16 laparoscopic, 33 open). Among the laparoscopic group, 81% were successfully completed laparoscopically...
April 10, 2021: Updates in Surgery
https://read.qxmd.com/read/33837935/inferior-mesenteric-arteriovenous-fistula-with-colonic-ischemia-a-case-report-and-review-of-the-literature
#11
Antonio Cubisino, Valentina Schembri, Boris Guiu
Inferior mesenteric arteriovenous fistula is a rare abnormal high flow communication with only 40 primary and secondary cases reported in literature. Shunting of arterial flow through the inferior mesenteric vein to the portal system can cause a variety of nonspecific clinical signs and symptoms usually associated with the diagnosis of arteriovenous malformation. Symptom intensities are flow-dependent and can range from minimal abdominal symptoms to severe heart failure due to left to right shunt. We report the case of a 72-year-old man without past history of abdominal surgery or trauma who was referred to our department for a 2-month history of intermittent diarrhea and abdominal pain caused by an arteriovenous fistula involving the left colic artery and the inferior mesenteric vein...
April 10, 2021: Clinical Journal of Gastroenterology
https://read.qxmd.com/read/33837931/does-inhaled-methoxyflurane-implement-fast-and-efficient-pain-management-in-trauma-patients-a-systematic-review-and-meta-analysis
#12
Hong Liu, Xi Fu, Yi-Feng Ren, Shi-Yan Tan, Si-Rui Xiang, Chuan Zheng, Feng-Ming You, Wei Shi, Lin-Jiong Li
INTRODUCTION: Evidence on the use of inhaled methoxyflurane in the management of trauma pain is conflicting and obfuscated. This study aimed to determine the efficacy and safety of inhaled methoxyflurane for trauma pain on the basis of published randomized controlled trials (RCTs). METHODS: RCTs assessing the efficacy of methoxyflurane in adults or adolescents with acute trauma pain published in PubMed, Web of Science, Embase, Cochrane Library, and Google Scholar were searched...
April 10, 2021: Pain and Therapy
https://read.qxmd.com/read/33837812/the-histopathological-synovitis-score-is-influenced-by-biopsy-location-in-patients-with-knee-osteoarthritis
#13
Haider Mussawy, Jozef Zustin, Andreas M Luebke, André Strahl, Veit Krenn, Wolfgang Rüther, Tim Rolvien
INTRODUCTION: Osteoarthritis (OA) and rheumatoid arthritis (RA) represent the most common forms of arthritis, which are mainly caused by mechanical and inflammatory components, respectively. Determination of synovial inflammation in synovial biopsies via the histopathological Krenn score may be crucial for correct diagnosis and treatment. Specifically, it remains unclear whether synovitis scores differ among multiple biopsy locations within a single joint. MATERIALS AND METHODS: Eighty synovial samples were taken from four standardized regions of the knee in 20 patients (ten primary OA, ten secondary OA) undergoing total knee arthroplasty (TKA) or total synovectomy...
April 10, 2021: Archives of Orthopaedic and Trauma Surgery
https://read.qxmd.com/read/33837811/future-burden-of-primary-and-revision-hip-arthroplasty-in-germany-a-socio-economic-challenge
#14
Alexander Klug, Dominik H Pfluger, Yves Gramlich, Reinhard Hoffmann, Philipp Drees, Karl Philipp Kutzner
INTRODUCTION: Total hip arthroplasty (THA) rates have increased dramatically in the recent decades worldwide, with Germany being one of the leading countries in the prevalence of THA. Simultaneously, a rising number of revision procedures is expected, which will put an enormous economic burden on future health care systems. METHODS: Nationwide data provided by the Federal Statistical Office of Germany were used to quantify primary and revision arthroplasty rates as a function of age and gender...
April 10, 2021: Archives of Orthopaedic and Trauma Surgery
https://read.qxmd.com/read/33837772/a-multilevel-examination-of-lifetime-aggression-integrating-cortical-thickness-personality-pathology-and-trauma-exposure
#15
Ana E Sheehan, Nadia Bounoua, Rickie Miglin, Jeffrey M Spielberg, Naomi Sadeh
Aggression represents a significant public health concern, causing serious physical and psychological harm. Although many studies have sought to characterize the etiology of aggression, research on the contributions of risk factors that span multiple levels of analysis for explaining aggressive behavior is lacking. To address this gap, we investigated the direct and unique contributions of cortical thickness (level 1), pathological personality traits (level 2), and trauma exposure (level 3) for explaining lifetime physical aggression in a high-risk sample of community adults (N = 129, 47...
April 10, 2021: Social Cognitive and Affective Neuroscience
https://read.qxmd.com/read/33837663/minimally-invasive-living-donor-liver-transplantation-pure-laparoscopic-explant-hepatectomy-and-graft-implantation-using-upper-midline-incision
#16
Kyung-Suk Suh, Suk Kyun Hong, Kwangpyo Hong, Eui Soo Han, Su Young Hong, Sanggyun Suh, Jeong-Moo Lee, YoungRok Choi, Nam-Joon Yi, Kwang-Woong Lee
Minimally invasive approaches, including laparoscopic procedures, have increasingly been applied in surgery due to their advantages such as reduced surgical trauma, a better quality of life, shorter hospital stay, and less postoperative morbidity compared with open surgeries.(1) Minimally invasive approaches in liver transplantation (LT) may have similar advantages for the recipients, including less pain and a shorter hospital stay, which could facilitate rehabilitation.
April 10, 2021: Liver Transplantation
https://read.qxmd.com/read/33837651/trauma-exposure-and-the-ptsd-symptoms-of-college-teachers-during-the-peak-of-the-covid-19-outbreak
#17
Changyu Fan, Ping Fu, Xueyan Li, Min Li, Miao Zhu
This study aimed to explore influencing factors for the psychological impact of COVID-19 on Wuhan college teachers, post-traumatic stress symptoms in particular, so as to inform evidence-based strategy development to ameliorate such adverse impacts. An online survey was conducted from 26 to 29 April 2020, and 1650 teachers (47.54% male; M=40.28 years, SD=8.3 years) enrolled in Wuhan universities and colleges participated. The results showed that the overall incidence of PTSD among college teachers was as high as 24...
April 9, 2021: Stress and Health: Journal of the International Society for the Investigation of Stress
https://read.qxmd.com/read/33837501/news-journalists-and-postruamatic-stress-disorder-a-review-of-literature-2011-2020
#18
REVIEW
Raymond B Flannery
Research has demonstrated that first responders may develop psychological trauma/ posttraumatic stress disorder (PTSD) in the performance of their duties. Often overlooked in these studies of police, firefighters, and paramedics is an additional group of providers who also respond to these same events: news journalists and photo journalists. Although limited in scope, the research literature from 1980 to 2010 assessed an association between PTSD and some news journalists. The strength of these findings are limited due to serious methodological limitations...
April 10, 2021: Psychiatric Quarterly
https://read.qxmd.com/read/33837474/outcome-of-revision-surgery-for-adverse-local-tissue-reactions-in-patients-with-recalled-total-hip-arthroplasty
#19
Christian Klemt, Sakkadech Limmahakhun, Georges Bounajem, Christopher M Melnic, Michael J Harvey, Young-Min Kwon
INTRODUCTION: Recalls of total hip arthroplasty (THA) implants, including metal-on-metal (MoM) THA and dual taper stems, due to increased risk of adverse local tissue reaction (ALTR), represent a challenge for both surgeons and patients. This study aims to analyze the revision surgery outcomes for ALTR in patients with recalled THA implants. METHODS: A total of 118 consecutive patients who underwent revision surgery due to ALTR with recalled THA were analyzed. Sub-group analysis was performed for recalled MoM THAs, head-neck modular stems, and dual taper neck-stems...
April 9, 2021: Archives of Orthopaedic and Trauma Surgery
https://read.qxmd.com/read/33837452/the-impact-of-digitisation-of-a-virtual-fracture-clinic-on-referral-quality-outcomes-and-assessment-times
#20
Benjamin M Sephton, Hannah Morley, Piyush Mahapatra, Michael Shenouda, Mustafa Al-Yaseen, Darryl E Bernstein, George Cross, Daniel E Dalili, Amrit Gurung, Atul Kamat, Andrew J Kuc, Aisha R Mohammed, Mehreen Paraouty, Amsanaa Ponniah, Ben Sluckis, Krisztian Deierl
BACKGROUND: Virtual fracture clinics (VFCs) have become widely adopted, aiming to improve efficiency, standardise patient care and reduce clinic appointments for injuries that can be managed conservatively. A variety of means exist to manage VFC referrals and assessment, including paper-based and digital methods. This study assesses VFC referral quality and outcomes before and after implementation of a digital VFC referral and management system. METHODS: A retrospective analysis was conducted of all VFC referrals and assessments from July 2017-March 2020 in a large UK district general hospital...
April 9, 2021: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
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