keyword
https://read.qxmd.com/read/38731361/epidemiology-tools-to-evaluate-the-control-of-proliferative-enteropathy-in-commercial-pig-herds
#41
JOURNAL ARTICLE
Alison Collins, Cherie Collins
Proliferative enteropathy (PE) is characterized by diarrhea and reduced weight gains in growing pigs and intestinal hemorrhage in finishers. Vaccination, antibiotic medication, and improved hygiene can control PE, but their efficacy depends upon the epidemiology of PE. This study monitored the timing and severity of PE in 84 commercial pens across seven treatments, including disinfection, vaccination, no treatment, medication with olaquindox (50, 25 and 12.5 ppm), and combined disinfection and vaccination. Vaccination with or without lime disinfection suppressed clinical signs of PE and reduced the number of excreted L...
April 30, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38730533/developmental-surveillance-and-screening-practices-in-a-pediatric-oncology-clinic-initial-progress-of-a-quality-improvement-study
#42
JOURNAL ARTICLE
Lila M Pereira, Madeline H Bono, Samuel Hilbert
BACKGROUND: Pediatric cancer patients' oncology teams regularly take on a primary care role, but due to the urgent nature of cancer treatment, developmental screenings may be deprioritized. This leaves patients at risk of developmental diagnoses and referrals being delayed. AIMS: Clarify the current developmental surveillance and screening practices of one pediatric oncology team. MATERIALS AND METHODS: Researchers reviewed charts for patients (n = 66) seen at a pediatric oncology clinic in a suburban academic medical center to determine engagement in developmental screening (including functioning around related areas such as speech, neurocognition, etc...
May 2024: Psycho-oncology
https://read.qxmd.com/read/38729236/cytotoxic-potential-and-metabolomic-profiling-of-alkaloid-rich-fraction-of-tylophora-indica-leaves
#43
JOURNAL ARTICLE
Mohd Adnan Kausar, Shabana Parveen, Sadaf Anwar, Sadaf, Sheersh Massey, Hemat El-Sayed El-Horany, Farida Habib Khan, Mona Shahein, Syed Akhtar Husain
Tylophora indica (Burm f.) Merrill, belong to family Asclepiadaceae, is considered to be a natural remedy with high medicinal benefits. The objective of this work is to assess the metabolomic profile of T. indica leaves enriched in alkaloids, as well as to evaluate the in vitro cytotoxicity of these leaves using the MTT assay on human breast MCF-7 and liver HepG2 cancer cell lines. Dried leaves of T. indica were extracted by sonication, using methanol containing 2 % (v/v) of acetic acid and obtained fraction was characterized by HPTLC and UPLC-MS...
May 8, 2024: Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids
https://read.qxmd.com/read/38728092/a-national-survey-of-pregnancy-and-parenthood-among-nephrology-trainees-a-focus-on-nephrology-fellowship
#44
JOURNAL ARTICLE
Angelina Dixon, Nisha Bansal, Susanne B Nicholas, Anna Ostrow, Jessica Kendrick
BACKGROUND: National and international policies on parental leave for physician trainees are inconsistent. Physician trainees, including nephrology fellows, may be at higher risk of pregnancy complications. Physician trainees face barriers in meeting their breastfeeding goals and in finding childcare due to nontraditional work hours with extended or unpredictable shifts. Here, we examine awareness of current policies in United States (US) nephrology fellowship programs regarding parental leave, pregnancy/breastfeeding accommodations, and fellows' perspectives on family planning...
May 10, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38724992/overlooked-by-the-obstetric-gaze-how-women-with-persistent-health-problems-due-to-severe-perineal-trauma-experience-encounters-with-healthcare-services-a-qualitative-study
#45
JOURNAL ARTICLE
Katharina Tjernström, Inger Lindberg, Maria Wiklund, Margareta Persson
BACKGROUND: During the first year postpartum, about 25 per cent of Swedish women with severe perineal trauma (SPT), i.e., a third- or fourth-degree perineal laceration at childbirth, are unsatisfied with their healthcare contacts. Further, there is a lack of research on the more long-term experiences of healthcare encounters among women with persistent SPT-related health problems. This study explores how women with self-reported persistent SPT-related health problems experience their contact with healthcare services 18 months to five years after childbirth when the SPT occurred...
May 9, 2024: BMC Health Services Research
https://read.qxmd.com/read/38724761/machine-learning-to-predict-outcomes-of-fetal-cardiac-disease-a-pilot-study
#46
JOURNAL ARTICLE
L E Nield, C Manlhiot, K Magor, L Freud, B Chinni, A Ims, N Melamed, O Nevo, T Van Mieghem, D Weisz, S Ronzoni
Prediction of outcomes following a prenatal diagnosis of congenital heart disease (CHD) is challenging. Machine learning (ML) algorithms may be used to reduce clinical uncertainty and improve prognostic accuracy. We performed a pilot study to train ML algorithms to predict postnatal outcomes based on clinical data. Specific objectives were to predict (1) in utero or neonatal death, (2) high-acuity neonatal care and (3) favorable outcomes. We included all fetuses with cardiac disease at Sunnybrook Health Sciences Centre, Toronto, Canada, from 2012 to 2021...
May 9, 2024: Pediatric Cardiology
https://read.qxmd.com/read/38724094/-toxic-debate-over-treatment-for-gender-dysphoria-in-uk-leaves-judges-without-expert-medical-witnesses
#47
JOURNAL ARTICLE
Clare Dyer
No abstract text is available yet for this article.
May 9, 2024: BMJ: British Medical Journal
https://read.qxmd.com/read/38723584/our-hands-are-tied-abortion-bans-and-hesitant-medicine
#48
JOURNAL ARTICLE
Anna-Grace Lilly, Isabelle P Newman, Sophie Bjork-James
Trained for decades to analyze risks, benefits, unique body compositions, and complex medical scenarios, healthcare providers are now faced with one of medicine's most trying obstacles: how to practice medicine when new abortion bans contradict best practice standards. Drawn from qualitative interviews with medical providers in Tennessee, USA conducted between October 2022 and December 2022, this study shows how medical providers often must make medical decisions based on legal risks as opposed to standards of care...
April 26, 2024: Social Science & Medicine
https://read.qxmd.com/read/38723051/forgotten-clientele-a-systematic-review-of-patient-centered-pathology-reports
#49
JOURNAL ARTICLE
Eric Steimetz, Elmira Mostafidi, Carolina Castagna, Raavi Gupta, Rosemary Frasso
CONTEXT: Patient portals, designed to give ready access to medical records, have led to important improvements in patient care. However, there is a downside: much of the information available on portals is not designed for lay people. Pathology reports are no exception. Access to complex reports often leaves patients confused, concerned and stressed. We conducted a systematic review to explore recommendations and guidelines designed to promote a patient centered approach to pathology reporting...
2024: PloS One
https://read.qxmd.com/read/38722723/bilstm-based-joint-torque-prediction-from-mechanomyogram-during-isometric-contractions-a-proof-of-concept-study
#50
JOURNAL ARTICLE
Jongsang Son, Fandi Shi, William Zev Rymer
Quantifying muscle strength is an important measure in clinical settings; however, there is a lack of practical tools that can be deployed for routine assessment. The purpose of this study is to propose a deep learning model for ankle plantar flexion torque prediction from time-series mechanomyogram (MMG) signals recorded during isometric contractions (i.e., a similar form to manual muscle testing procedure in clinical practice) and to evaluate its performance. Four different deep learning models in terms of model architecture (based on a stacked bidirectional long short-term memory and dense layers), the number of units (from 32 to 512), and dropout ratio (from 0...
May 9, 2024: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://read.qxmd.com/read/38722566/targeting-resistant-breast-cancer-stem-cells-in-a-three-dimensional-culture-model-with-oleuropein-encapsulated-in-methacrylated-alginate-microparticles
#51
JOURNAL ARTICLE
Ozlem Altundag-Erdogan, Rumeysa Tutar, Elif Yüce, Betül Çelebi-Saltik
BACKGROUND: Cancer stem cells (CSCs) are a subpopulation of cancer cells that are believed to be responsible for tumor initiation, progression, metastasis, and resistance to conventional therapies. Oleuropein as a natural compound found in olive leaves and olive oil, has potential therapeutic effects in cancer treatment, particularly in targeting CSCs. It induces apoptosis in CSCs while sparing normal cells, inhibit proliferation, migration, and invasion, and suppress the self-renewal ability of CSCs...
May 9, 2024: Daru: Journal of Faculty of Pharmacy, Tehran University of Medical Sciences
https://read.qxmd.com/read/38721468/pubourethral-and-uterosacral-male-analogues-suggest-parallel-male-female-pelvic-anatomy-and-symptom-pathogenesis
#52
REVIEW
Ahmed Farag, Sidi Muctar, Peter Petros
The thesis that functional/dysfunctional male/female pelvic floor anatomy are parallel, originated from two studies: a successful retropubic perineal male sling for post-prostatectomy stress urinary incontinence (SUI) and discovery of a male uterosacral ligament (USL) analogue, we named "prostatosacral ligament" (PSL). In 25 out of the studied 27 males (92.6%), it starts on both sides of the median sulcus of the prostate the ligament passes lateral to the rectum being fused with the lateral margin of the mesorectum before leaving it as it thins out to be attached posteriorly similar to the USL...
April 22, 2024: Annals of Translational Medicine
https://read.qxmd.com/read/38720674/pathology-and-resection-margins-following-mastectomy-prior-to-immediate-breast-reconstruction
#53
REVIEW
Annemette Kirkegaard Jørgensen, Camilla Bille, Anne Marie Bak Jylling, Orit Kaidar-Person, Trine Tramm
Risk of local recurrence (LR) (and even distant disease-free survival) after mastectomy is associated with margin status. Furthermore, the vast majority of LR are located at the anterior (superficial) margin. Margins in mastectomy are considered anatomical borders and not true resection margins; such a conception may erroneously lead to underestimation of the risk of LR after mastectomy. If dissection is accurate along the fascia, only skin, subcutaneous tissue and minimal residual breast gland tissue (rBGT) are expected to remain in the patient...
April 29, 2024: Gland Surgery
https://read.qxmd.com/read/38718100/process-evaluation-of-the-co-work-care-model-collaboration-and-a-person-centred-dialogue-meeting-for-patients-with-common-mental-disorder-in-primary-health-care
#54
JOURNAL ARTICLE
Eva-Lisa Petersson, Karin Törnbom, Cecilia Björkelund, Margaretha Jerlock, Dominique Hange, Camilla Udo, Irene Svenningsson
RATIONALE: To ensure optimal patient care based on evidence, it is crucial to understand how to implement new methods in practice. However, intervention studies often overlook parts of the implementation process. A comprehensive process evaluation is necessary to understand why interventions succeed or fail in specific contexts and to integrate new knowledge into daily practice. This evaluation examines the full implementation of the Co-Work-Care model in Swedish primary healthcare to identify strengths and weaknesses...
May 8, 2024: Scandinavian Journal of Caring Sciences
https://read.qxmd.com/read/38715115/study-of-medicinal-plants-used-in-ethnoveterinary-medical-system-in-riverine-areas-of-punjab-pakistan
#55
JOURNAL ARTICLE
Muhammad Umair, Muhammad Altaf, Taswar Ahsan, Rainer W Bussmann, Arshad Mehmood Abbasi, Mansour K Gatasheh, Mohamed Elrobh
BACKGROUND: The use of medicinal plants to treat various veterinary illnesses has been practiced for millennia in many civilizations. Punjab is home to a diverse ethnic community, the majority of whom work in dairy farming, agriculture, and allied professions and have indigenous practices of treating animal illnesses using native flora. This study was designed to (1) document and preserve information about the applications of medicinal plant species in ethnoveterinary remedies among inhabitants of Punjab, Pakistan, and (2) identify popular plants for disease treatment by quantitative analysis of the obtained data and to assess the pharmacological relevance of these species...
May 7, 2024: Journal of Ethnobiology and Ethnomedicine
https://read.qxmd.com/read/38714610/the-conceptual-injustice-of-the-brain-death-standard
#56
JOURNAL ARTICLE
William Choi
Family disputes over the diagnosis of brain death have caused much controversy in the bioethics literature over the conceptual validity of the brain death standard. Given the tenuous status of brain death as death, it is pragmatically fruitful to reframe intractable debates about the metaphysical nature of brain death as metalinguistic disputes about its conceptual deployment. This new framework leaves the metaphysical debate open and brings into focus the social functions that are served by deploying the concept of brain death...
May 7, 2024: Theoretical Medicine and Bioethics
https://read.qxmd.com/read/38713767/professionalism-policies-and-practices-as-experienced-by-first-generation-medical-students-residents-and-physicians
#57
JOURNAL ARTICLE
Lynn Shaull, Paolo C Martin, Jessica Bunin, Tasha R Wyatt
Phenomenon : While professionalism is largely understood to be complex and dynamic, it is oftentimes implemented as if it were static and concrete. As a result, policies and practices reflect dominant historical norms of the medical profession, which can cause tension for trainees from marginalized groups. One such group comprises those who identify as first-generation physicians - those whose parents have not earned an associate's degree or higher. This group is highly diverse in terms of gender, race, ethnicity, and socioeconomic status; however, their experiences with institutional professionalism policies and practices has not yet been fully explored...
May 7, 2024: Teaching and Learning in Medicine
https://read.qxmd.com/read/38713464/variation-in-oral-board-examination-accommodations-among-specialties
#58
JOURNAL ARTICLE
Dana G Rowe, Antoinette J Charles, Emily J Luo, Alissa M Arango, James E Herndon, Harrison Hockenberry, Cynthia K Shortell, C Rory Goodwin, Melissa M Erickson
IMPORTANCE: Board certification can have broad implications for candidates' career trajectories, and prior research has found sociodemographic disparities in pass rates. Barriers in the format and administration of the oral board examinations may disproportionately affect certain candidates. OBJECTIVE: To characterize oral certifying examination policies and practices of the 16 Accreditation Council for Graduate Medical Education (ACGME)-accredited specialties that require oral examinations...
May 1, 2024: JAMA Network Open
https://read.qxmd.com/read/38712444/pediatric-psychosocial-risk-index-factor-analysis-and-item-reduction-study
#59
JOURNAL ARTICLE
Justine Cohen-Silver, Katherine Cost, Jose Navarro, Jonathon L Maguire
OBJECTIVES: The Pediatric psychoSocial Risk Index (PSRI) is psychosocial risk screening instrument for health practitioners. The objective of this study was to confirm validity evidence of a truncated version of PSRI. METHODS: PSRI was completed initially by 100 parents of children aged 0 to 18 years admitted to a tertiary hospital; 50 parents repeated the PSRI 3 days later. Analysis includes principal component analysis (PCA) to include the least number of items that explain the most variance in a shortened version of PSRI as well as confirming test-retest reliability and internal consistency of the shortened instrument...
May 7, 2024: Hospital Pediatrics
https://read.qxmd.com/read/38710259/treatment-effect-modifiers-for-return-to-work-in-patients-with-musculoskeletal-disorders
#60
JOURNAL ARTICLE
Martjie Venter, Margreth Grotle, Britt Elin Øiestad, Fiona Aanesen, Alexander Tingulstad, Tarjei Rysstad, Michael C Ferraro, James H McAuley, Aidan G Cashin
Investigating how individual characteristics modify treatment effects can improve understanding, interpretation, and translation of trial findings. The purpose of this secondary analysis was to identify treatment effect modifiers of the MI-NAV trial, a three arm, parallel randomized controlled trial which compared motivational interviewing and stratified vocational advice intervention in addition to usual case management, to usual case management alone. This study included (n=514) participants with musculoskeletal disorders on sick leave for at least 50% of their contracted work hours for at least 7 consecutive weeks with the Norwegian Labour and Welfare Administration...
May 4, 2024: Journal of Pain
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