IVH | Page 2

Kelly S Chu, Prakesh S Shah, Wendy L Whittle, Rory Windrim, Kellie E Murphy
Purpose: To determine the feasibility of a randomized controlled trial of delayed umbilical cord clamping in preterm infants. Methods: Following informed consent, women between 24 to 32 weeks gestation experiencing imminent preterm birth were randomly assigned to either an immediate cord clamping (ICC) or delayed cord clamping (DCC) group. Umbilical cord clamping directions were 0-15 s for the ICC group and 30-45 s for the DCC group. Information regarding recruitment rate and trial compliance was collected...
December 25, 2019: Journal of Maternal-fetal & Neonatal Medicine
Hamid Kariman, Hamidreza Hatamabadi, Majid Shojaee, Farhad Asarzadegan, Simin Saljughi
Introduction: Predicting the outcome of patients with intracranial hemorrhage (ICH) is the area of interest for in charge physicians as well as patients and their associates. This study aimed to evaluate the accuracy of SUSPEKT score in predicting one-month outcome of patients with hemorrhagic stroke. Methods: This prospective cross sectional study was conducted on > 18 years old patients with non-traumatic supra-tentorial ICH admitted to emergency department, from February 2017 to January 2018...
2019: Archives of Academic Emergency Medicine
Alexander K Grevsen, Claus V B Hviid, Anne K Hansen, Anne-Mette Hvas
Intraventricular hemorrhage (IVH) affects up to 22% of extremely low birth weight neonates. Impaired coagulation might contribute to the pathogenesis of IVH. The aims of this study were to summarize the current knowledge on the role of platelet indices in premature neonates with IVH and to provide an overview of secondary hemostasis parameters as well as fibrinolysis in premature neonates with IVH. The review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines...
December 20, 2019: Seminars in Thrombosis and Hemostasis
Evan Luther, David McCarthy, Shaina Sedighim, Toba Niazi
PURPOSE: Endoscopic third ventriculostomy (ETV) has gained traction as a method for treating post-hemorrhagic hydrocephalus of prematurity (PHHP) in an effort to obviate lifelong shunt dependence in neonates. However, data remains limited regarding inpatient failures. METHODS: A retrospective analysis of the NIS between 1998 and 2014 was performed. Discharges with age < 1 year and ICD-9-CM codes indicating intraventricular hemorrhage of prematurity (772.1x) and ETV/shunt (02...
December 20, 2019: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Rebecca A Dorner, Marilee C Allen, Shenandoah Robinson, Bruno P Soares, Jamie Perin, Ezequiel Ramos, Gwendolyn Gerner, Vera Joanna Burton
OBJECTIVE: Brain injury remains a serious complication of prematurity. Almost half of infants with severe intraventricular hemorrhage (IVH) develop posthemorrhagic ventricular dilatation (PHVD) and 20% need surgery for posthemorrhagic hydrocephalus (PHH). This population is associated with an increased risk of later neurodevelopmental disability, but there is uncertainty about which radiological and examination features predict later disability. In this study the authors sought to devise and describe a novel combination of neurobehavioral examination and imaging for prediction of neurodevelopmental disability among preterm infants with PHVD and PHH...
December 20, 2019: Journal of Neurosurgery. Pediatrics
Ipsita R Goswami, Ayman Abou Mehrem, James Scott, Michael J Esser, Khorshid Mohammad
Aim: Safe limits of arterial partial pressure of carbon dioxide (PaCO2 ) and acidosis in premature infants are not well defined. Both respiratory and systemic illness along with center-specific ventilation strategies contribute to PaCO2 fluctuations and acid-base imbalances during the critical time period of first 72 h of life. This study evaluated the association between early blood gas parameters and intraventricular hemorrhage (IVH) in preterm infants. Methods: This retrospective observational study included neonates with a gestational age (GA) of ≤29 wks, who had at least 7 blood gas analysis done within the first 72 h of life...
December 18, 2019: Journal of Maternal-fetal & Neonatal Medicine
Qin Tang, Liheng Zhang, Huan Li, Yong Shao
Background: The clinical performance of fetal inflammatory response syndrome (FIRS) is often atypical. The aim of this meta-analysis is to investigate whether FIRS is associated with adverse neonatal outcomes. Methods: PubMed, Embase, and Cochrane Library were used in this study. The adverse neonatal outcomes data including neonatal early-onset sepsis (EOS), bronchopulmonary dysplasia (BPD), periventricular leukomalacia (PVL), intraventricular hemorrhage (IVH), respiratory distress syndrome (RDS), and neonatal death were collected to make analysis...
December 18, 2019: Journal of Maternal-fetal & Neonatal Medicine
Laura E Miller, Jason Z Stoller, María V Fraga
PURPOSE OF REVIEW: Point-of-care ultrasound (POCUS) is an emerging clinical tool in the neonatal intensive care unit (NICU). Recent literature describing the use of POCUS for various applications in the NICU has garnered increased interest among neonatologists. RECENT FINDINGS: Diagnostic applications for POCUS in the NICU include the evaluation and serial monitoring of common pulmonary diseases, hemodynamic instability, patent ductus arteriosus (PDA), persistent pulmonary hypertension of the newborn (PPHN), necrotizing enterocolitis (NEC), and intraventricular hemorrhage (IVH), among others...
December 13, 2019: Current Opinion in Pediatrics
Kentaro Tamura, Emma E Williams, Theodore Dassios, Anoop Pahuja, Katie A Hunt, Vadivelam Murthy, Prashanth Bhat, Ravindra Bhat, Anthony Milner, Anne Greenough
Abnormal levels of end-tidal carbon dioxide (EtCO2 ) during resuscitation in the delivery suite are associated with intraventricular haemorrhage (IVH) development. Our aim was to determine whether carbon dioxide (CO2 ) levels in the first 3 days after birth reflected abnormal EtCO2 levels in the delivery suite, and hence, a prolonged rather than an early insult resulted in IVH. In addition, we determined if greater EtCO2 level fluctuations during resuscitation occurred in infants who developed IVH. EtCO2 levels during delivery suite resuscitation and CO2 levels on the neonatal unit were evaluated in 58 infants (median gestational age 27...
December 17, 2019: European Journal of Pediatrics
Simone M Uniken Venema, Sandro Marini, H Bart Brouwers, Andrea Morotti, Daniel Woo, Christopher D Anderson, Jonathan Rosand
BACKGROUND AND OBJECTIVE: The aim of this study was to evaluate the impact of radiographic cerebral small vessel disease (CSVD) on the severity of acute intracerebral hemorrhage (ICH) as measured by: ICH volume, hematoma expansion, and extension of intraventricular hemorrhage (IVH). METHODS: CSVD was determined on baseline computed tomography (CT) scans of patients from the Ethnic and Racial Variations of Intracerebral Hemorrhage study through the extent of leukoaraiosis and cerebral atrophy using visual rating scales...
December 16, 2019: Neurocritical Care
Kimberley Whitehead, Laura Jones, Maria Pureza Laudiano-Dray, Judith Meek, Lorenzo Fabrizi
High-grade (large) germinal matrix-intraventricular haemorrhage (GM-IVH) is one of the most common causes of somatomotor neurodisability in pre-term infants. GM-IVH presents during the first postnatal week and can impinge on somatosensory circuits resulting in aberrant somatosensory cortical events straight after injury. Subsequently, somatosensory circuits undergo significant plastic changes, sometimes allowing the reinstatement of a somatosensory cortical response. However, it is not known whether this restructuring results in a full recovery of somatosensory functions...
November 28, 2019: NeuroImage: Clinical
Liang Yuan, Yi-Qing Shen, Xiong-Fei Xie, Wen-Song Yang, Rui Li, Lan Deng, Qi Li, Peng Xie
OBJECTIVE: Ultra-early hematoma growth (uHG) in acute intracerebral hemorrhage (ICH) has been well established and can improve spot sign in the prediction of hematoma expansion (HE) and poor outcome. This study aimed to investigate whether uHG can improve blend sign as a promising combining marker to stratify HE and poor outcome. PATIENTS AND METHODS: A consecutive cohort study in patients with primary ICH conducted in the First Affiliated Hospital of Chongqing Medical University...
November 28, 2019: Clinical Neurology and Neurosurgery
Zhao-Lan Cao, Jing-Jing Pan, Xian Shen, Xiao-Yu Zhou, Rui Cheng, Xiao-Guang Zhou, Yang Yang
BACKGROUND: Less invasive surfactant administration (LISA) seems to have a good application prospect both in experimental models and patients with respiratory distress syndrome (RDS). Data regarding the effect of LISA procedure on RDS are conflicting. METHODS: A search was conducted by two investigators involved in this research in PubMed, Embase, and Cochrane databases for studies in English, in Wanfang, VIP, and Cnki databases for Chinese studies (all last launched on 2018/12/18)...
December 12, 2019: Journal of the Chinese Medical Association: JCMA
Jun-Soo Cho, Sang-Uk Kim, Hyung-Jin Lee, Ji-Ho Yang, Il-Woo Lee, Jae-Hoon Sung
Objective: The spot sign on computed tomography angiography is little known about the relationship between the spot sign and the results of cerebral angiography We retrospectively analyzed the spot sign, digital subtraction angiography results, and other factors. Material and Methods: From December 2009 to May 2014, DSA was performed in 52 ICH patients with non-specific location or abnormalities on CTA findings. 26 of those patients, whose initial CTA showed the spot sign, were analyzed...
March 2019: Journal of Cerebrovascular and Endovascular Neurosurgery
Seung Soo Kim, Kyeong-O Go, Hyun Park, Kwangho Lee, Gyeong Hwa Ryu, Hye Jin Baek, Seunguk Jung, Chang Hyo Yoon, Young-Seop Park, Soo Hyun Hwang
The presence of primary intraventricular hemorrhage (IVH) without vascular lesion is very rare. We experienced solitary IVH without subarachnoid hemorrhage due to aneurysmal rupture in a 58-year-old man treated with coil embolization, which contributed to his good prognosis. After 33 days of hospitalization, he had mild right hemiplegic symptoms remaining, and he was transferred to a rehabilitation institute for further treatment. In cases of primary IVH, computed tomography angiography seems worthwhile for making a differential diagnosis, although the possibility of IVH due to cerebral aneurysmal rupture is very low...
March 2019: Journal of Cerebrovascular and Endovascular Neurosurgery
Bloeme van der Knoop, Inge Zonnenberg, Jonathan Verbeke, Linda de Vries, Lou Pistorius, Mirjam M van Weissenbruch, R Jeroen Vermeulen, Johanna de Vries
OBJECTIVES: To assess the additional value of fetal multiplanar (axial, coronal and sagittal) neurosonography and Magnetic Resonance Imaging (MRI) to axial ultrasound (US) planes to diagnose brain damage (visualized as periventricular echogenicity changes (PVE), intraventricular haemorrhage (IVH) and echogenicities in basal ganglia and/or thalami (BGTE)) and signal intensity changes in the equivalent brain areas on MRI in fetuses at high risk. METHODS: A prospective, multicenter, observational study...
December 11, 2019: Ultrasound in Obstetrics & Gynecology
Hunter Little, Jingqi Wang, Jean Duhamel, Xuesong Li, Markandeya Nagula, Victor Maurizot, Ivan Huc
This study introduces a global fluorescence decay analysis that substantially simplifies the acquisition and analysis of time-resolved fluorescence decays acquired with a vertically polarized excitation and vertically (IVV(t)) and horizontally (IVH(t)) polarized emission for time-resolved fluorescence anisotropy (TRFA) measurements. TRFA measurements were conducted whereby the IVV(t) and IVH(t) fluorescence decays of a series of oligoquinolines labeled at one end with an oligo(phenylene vinylene) dye (OPV-Qn with n = 4, 7, 17, 24, 33) were acquired according to the standard protocol that is currently accepted in the scientific literature which involves toggling the emission polarizer before fitting linear combinations of the IVV(t) and IVH(t) decays or acquiring the IVV(t) and IVH(t) decays with static polarizers before fitting them globally...
December 5, 2019: Analytical Chemistry
Andreea Matei, Louise Montalva, Alexa Goodbaum, Giuseppe Lauriti, Augusto Zani
AIM: To determine (1) the incidence of neurodevelopmental impairment (NDI) in necrotising enterocolitis (NEC), (2) the impact of NEC severity on NDI in these babies and (3) the cerebral lesions found in babies with NEC. METHODS: Systematic review: three independent investigators searched for studies reporting infants with NDI and a history of NEC (PubMed, Medline, Cochrane Collaboration, Scopus). Meta-analysis: using RevMan V.5.3, we compared NDI incidence and type of cerebral lesions between NEC infants versus preterm infants and infants with medical vs surgical NEC...
December 4, 2019: Archives of Disease in Childhood. Fetal and Neonatal Edition
(no author information available yet)
Objective: To study the short-term outcomes and their related risk factors of extremely preterm infants (EPI) and extremely low birth weight infants (ELBWI) in Guangdong province. Methods: The neonatal and corresponding maternal medical records of 2 392 cases of EPI and ELBWI discharged from 26 tertiary hospitals in Guangdong province during 2013-2017 were collected. Chi -square test or linear-by-linear association chi -square was used to analyze the following data on an annual basis: (1) the proportion of EPI and ELBWI in all discharged infants and preterm infants; (2) the difference in survival rate of EPI and ELBWI in different regions and types of hospital; and (3) the difference in incidence of complications...
December 2, 2019: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
Albert M Isaacs, Christopher D Smyser, Rachel E Lean, Dimitrios Alexopoulos, Rowland H Han, Jeffrey J Neil, Sophia A Zimbalist, Cynthia E Rogers, Yan Yan, Joshua S Shimony, David D Limbrick
OBJECTIVES: Injury to the preterm lateral ventricular perimeter (LVP), which contains the neural stem cells responsible for brain development, may contribute to the neurological sequelae of intraventricular hemorrhage (IVH) and post-hemorrhagic hydrocephalus of prematurity (PHH). This study utilizes diffusion MRI (dMRI) to characterize the microstructural effects of IVH/PHH on the LVP and segmented frontal-occipital horn perimeters (FOHP). STUDY DESIGN: Prospective study of 56 full-term infants, 72 very preterm infants without brain injury (VPT), 17 VPT infants with high-grade IVH without hydrocephalus (HG-IVH), and 13 VPT infants with PHH who underwent dMRI at term equivalent...
2019: NeuroImage: Clinical
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