Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#21
JOURNAL ARTICLE
Joana Ferrer-Fàbrega, Gabriel Cárdenas, Víctor Sapena, Ángeles García-Criado, Marta Barrufet, Carles Pérez, Rocío García-Pérez, Ramón Rull, Miguel Ángel López-Boado, Emma Folch-Puy, Alba Torroella, Pedro Ventura-Aguiar, Federico Cofan, Enric Esmatjes, Antonio Amor, Fritz Diekmann, Laureano Fernández-Cruz, Juan Carlos García-Valdecasas, Josep Fuster
OBJECTIVE: To determine the role of the arterial splenomesenteric anastomosis (ASMA) vascular reconstruction technique in terms of arterial vascular complications in pancreas transplant (PT) recipients. SUMMARY BACKGROUND DATA: The ASMA technique was first described in 1992 by Hospital Clínic Barcelona group. Regardless that the iliac Y-graft technique is the most frequently used worldwide, evidence of arterial complications and implications of using a different back-table reconstruction is conspicuously absent in the literature...
December 25, 2023: Annals of Surgery
#22
JOURNAL ARTICLE
Florent Rossi, Caroline Duchaine, Romie Tignat-Perrier, Muriel Joly, Catherine Larose, Aurélien Dommergue, Nathalie Turgeon, Marc Veillette, Karine Sellegri, Jean-Luc Baray, Pierre Amato
The recent characterization of antibiotic resistance genes (ARGs) in clouds evidenced that the atmosphere actively partakes in the global spreading of antibiotic resistance worldwide. Indeed, the outdoor atmosphere continuously receives large quantities of particles of biological origins, emitted from both anthropogenic or natural sources at the near Earth's surface. Nonetheless, our understanding of the composition of the atmospheric resistome, especially at mid-altitude (i.e. above 1000 m a...
December 23, 2023: Science of the Total Environment
#23
Antoine Poli, Camilla Frieri, Thibaud Lefebvre, Juliette Delforge, Arienne Mirmiran, Neila Talbi, Boualem Moulouel, Marion Six, Valérie Paradis, Nathalie Parquet, Hervé Puy, Caroline Schmitt, Elisabeth Aslangul, Flore Sicre de Fontbrune, Laurent Gouya
Erythropoietic protoporphyria (EPP) is a rare metabolic disease of the heme biosynthetic pathway where an enzymatic dysfunction results in protoporphyrin IX (PPIX) accumulation in erythroid cells. The porphyrins are photo-reactive and are responsible for severe photosensitivity in patients, thus drastically decreasing their quality of life. The liver eliminates PPIX and as such, the main and rare complication of EPP is progressive cholestatic liver disease, which can lead to liver failure. The management of this complication is challenging, as it often requires a combination of approaches to promote PPIX elimination and suppress the patient's erythropoiesis...
December 2023: Molecular Genetics and Metabolism Reports
#24
JOURNAL ARTICLE
Michael A Pfeffer, Tia C L Kohs, Helen H Vu, Kelley R Jordan, Jenny Si Han Wang, Christina U Lorentz, Erik I Tucker, Cristina Puy, Sven R Olson, Thomas G DeLoughery, Monica T Hinds, Ravi S Keshari, David Gailani, Florea Lupu, Owen J T McCarty, Joseph J Shatzel
BACKGROUND: Despite the ubiquitous utilization of central venous catheters in clinical practice, their use commonly provokes thromboembolism. No prophylactic strategy has shown sufficient efficacy to justify routine use. Coagulation factors FXI (factor XI) and FXII (factor XII) represent novel targets for device-associated thrombosis, which may mitigate bleeding risk. Our objective was to evaluate the safety and efficacy of an anti-FXI mAb, gruticibart (AB023), in a prospective, single-arm study of patients with cancer receiving central line placement...
November 16, 2023: Arteriosclerosis, Thrombosis, and Vascular Biology
#25
JOURNAL ARTICLE
Yajie Hu, Mingmao Wu, Fengyao Chi, Guobin Lai, Puying Li, Wenya He, Bing Lu, Chuanxin Weng, Jinguo Lin, Fengen Chen, Huhu Cheng, Feng Liu, Lan Jiang, Liangti Qu
Electrochemical capacitors are expected to replace conventional electrolytic capacitors in line filtering for integrated circuits and portable electronics1-8 . However, practical implementation of electrochemical capacitors into line-filtering circuits has not yet been achieved owing to the difficulty in synergistic accomplishment of fast responses, high specific capacitance, miniaturization and circuit-compatible integration1,4,5,9-12 . Here we propose an electric-field enhancement strategy to promote frequency characteristics and capacitance simultaneously...
November 15, 2023: Nature
#26
JOURNAL ARTICLE
Samuele Lo Piano, Máté János Lőrincz, Arnald Puy, Steve Pye, Andrea Saltelli, Stefán Thor Smith, Jeroen van der Sluijs
This article explores how the modeling of energy systems may lead to an undue closure of alternatives by generating an excess of certainty around some of the possible policy options. We retrospectively exemplify the problem with the case of the International Institute for Applied Systems Analysis (IIASA) global modeling in the 1980s. We discuss different methodologies for quality assessment that may help mitigate this issue, which include Numeral Unit Spread Assessment Pedigree (NUSAP), diagnostic diagrams, and sensitivity auditing (SAUD)...
November 14, 2023: Risk Analysis: An Official Publication of the Society for Risk Analysis
#27
JOURNAL ARTICLE
M L Robinson, P G Hahn, B D Inouye, N Underwood, S R Whitehead, K C Abbott, E M Bruna, N I Cacho, L A Dyer, L Abdala-Roberts, W J Allen, J F Andrade, D F Angulo, D Anjos, D N Anstett, R Bagchi, S Bagchi, M Barbosa, S Barrett, C A Baskett, E Ben-Simchon, K J Bloodworth, J L Bronstein, Y M Buckley, K T Burghardt, C Bustos-Segura, E S Calixto, R L Carvalho, B Castagneyrol, M C Chiuffo, D Cinoğlu, E Cinto Mejía, M C Cock, R Cogni, O L Cope, T Cornelissen, D R Cortez, D W Crowder, C Dallstream, W Dáttilo, J K Davis, R D Dimarco, H E Dole, I N Egbon, M Eisenring, A Ejomah, B D Elderd, M-J Endara, M D Eubanks, S E Everingham, K N Farah, R P Farias, A P Fernandes, G W Fernandes, M Ferrante, A Finn, G A Florjancic, M L Forister, Q N Fox, E Frago, F M França, A S Getman-Pickering, Z Getman-Pickering, E Gianoli, B Gooden, M M Gossner, K A Greig, S Gripenberg, R Groenteman, P Grof-Tisza, N Haack, L Hahn, S M Haq, A M Helms, J Hennecke, S L Hermann, L M Holeski, S Holm, M C Hutchinson, E E Jackson, S Kagiya, A Kalske, M Kalwajtys, R Karban, R Kariyat, T Keasar, M F Kersch-Becker, H M Kharouba, T N Kim, D M Kimuyu, J Kluse, S E Koerner, K J Komatsu, S Krishnan, M Laihonen, L Lamelas-López, M C LaScaleia, N Lecomte, C R Lehn, X Li, R L Lindroth, E F LoPresti, M Losada, A M Louthan, V J Luizzi, S C Lynch, J S Lynn, N J Lyon, L F Maia, R A Maia, T L Mannall, B S Martin, T J Massad, A C McCall, K McGurrin, A C Merwin, Z Mijango-Ramos, C H Mills, A T Moles, C M Moore, X Moreira, C R Morrison, M C Moshobane, A Muola, R Nakadai, K Nakajima, S Novais, C O Ogbebor, H Ohsaki, V S Pan, N A Pardikes, M Pareja, N Parthasarathy, R R Pawar, Q Paynter, I S Pearse, R M Penczykowski, A A Pepi, C C Pereira, S S Phartyal, F I Piper, K Poveda, E G Pringle, J Puy, T Quijano, C Quintero, S Rasmann, C Rosche, L Y Rosenheim, J A Rosenheim, J B Runyon, A Sadeh, Y Sakata, D M Salcido, C Salgado-Luarte, B A Santos, Y Sapir, Y Sasal, Y Sato, M Sawant, H Schroeder, I Schumann, M Segoli, H Segre, O Shelef, N Shinohara, R P Singh, D S Smith, M Sobral, G C Stotz, A J M Tack, M Tayal, J F Tooker, D Torrico-Bazoberry, K Tougeron, A M Trowbridge, S Utsumi, O Uyi, J L Vaca-Uribe, A Valtonen, L J A van Dijk, V Vandvik, J Villellas, L P Waller, M G Weber, A Yamawo, S Yim, P L Zarnetske, L N Zehr, Z Zhong, W C Wetzel
Interactions between plants and herbivores are central in most ecosystems, but their strength is highly variable. The amount of variability within a system is thought to influence most aspects of plant-herbivore biology, from ecological stability to plant defense evolution. Our understanding of what influences variability, however, is limited by sparse data. We collected standardized surveys of herbivory for 503 plant species at 790 sites across 116° of latitude. With these data, we show that within-population variability in herbivory increases with latitude, decreases with plant size, and is phylogenetically structured...
November 10, 2023: Science
#28
JOURNAL ARTICLE
Chao Xiong, Yaohua Wang, Yue Li, Jinhai Yu, Sha Wu, Lili Wu, Boyuan Zhang, Yunxiu Chen, Puying Gan, Hongfei Liao
BACKGROUND: Thyroid associated ophthalmopathy (TAO) is an organ-specific autoimmune disease that has a significant impact on individuals and society. The etiology of TAO is complicated and poorly understood. Thus, the goal of this study was to use bioinformatics to look into the pathogenesis of TAO and to identify the optimum feature genes (OFGs) and immune infiltration patterns of TAO. METHODS: Firstly, the GSE58331 microarray data set was utilized to find 366 differentially expressed genes (DEGs)...
2023: Frontiers in Endocrinology
#29
JOURNAL ARTICLE
Gerard Grau, Eduard Brunet-Mas, Laura Patricia Llovet, Patricia Pedregal, Albert Villoria, Luigi Melcarne, Anna Puy, Belen Garcia-Sague, Luis Enrique Frisancho, María José Ramírez-Lázaro, Sergio Lario, Xavier Calvet
BACKGROUND AND OBJECTIVES: Thiopurines are an effective treatment for the maintenance of remission in inflammatory bowel disease (IBD). They can present adverse effects (AEs), with myelotoxicity being the most relevant. This study aims to determine the incidence of AEs related to the starting of thiopurines in our centre. METHODOLOGY: Retrospective study. The AEs in patients that were started on thiopurines between January 2016 and June 2020 were registered, with a two-year follow-up...
October 17, 2023: Journal of Clinical Medicine
#30
JOURNAL ARTICLE
Amir Hossein Davarpanah Jazi, Mohammad Mahjoubi, Shahab Shahabi, Aayed R Alqahtani, Ashraf Haddad, Abdolreza Pazouki, Arun Prasad, Bassem Y Safadi, Sonja Chiappetta, Halit Eren Taskin, Helmuth Thorlakur Billy, Kazunori Kasama, Kamal Mahawar, Khaled Gawdat, Karl Peter Rheinwalt, Karl A Miller, Lilian Kow, Manoel Galvao Neto, Wah Yang, Mariano Palermo, Omar M Ghanem, Panagiotis Lainas, Ralph Peterli, Radwan Kassir, Ramon Vilallonga Puy, Rui José Da Silva Ribeiro, Sergio Verboonen, Tadeja Pintar, Asim Shabbir, Mario Musella, Mohammad Kermansaravi
BACKGROUND: Recent advancements in artificial intelligence, such as OpenAI's ChatGPT-4, are revolutionizing various sectors, including healthcare. This study investigates the use of ChatGPT-4 in identifying suitable candidates for bariatric surgery and providing surgical recommendations to improve decision-making in obesity treatment amid the global obesity epidemic. METHODS: We devised ten patient scenarios, thoughtfully encompassing a spectrum that spans from uncomplicated cases to more complex ones...
October 27, 2023: Obesity Surgery
#31
JOURNAL ARTICLE
Samantha A Moellmer, Cristina Puy, Owen J T McCarty
Unique among coagulation factors, the coagulation factor (F) XI arose through a duplication of the gene KLKB1 that encodes for plasma prekallikrein. This evolutionary origin sets FXI apart structurally as it is a homodimer with two identical subunits comprised of 4 apple and 1 catalytic domain. Each domain exhibits unique affinities for binding partners within the coagulation cascade, regulating the conversion of FXI to a serine protease as well as the selectivity of substrates cleaved by the active form of FXI...
October 24, 2023: Blood
#32
RANDOMIZED CONTROLLED TRIAL
Evie van der Spoel, Nicolien A van Vliet, Rosalinde K E Poortvliet, Robert S Du Puy, Wendy P J den Elzen, Terence J Quinn, David J Stott, Naveed Sattar, Patricia M Kearney, Manuel R Blum, Heba Alwan, Nicolas Rodondi, Tinh-Hai Collet, Rudi G J Westendorp, Bart E Ballieux, J Wouter Jukema, Olaf M Dekkers, Jacobijn Gussekloo, Simon P Mooijaart, Diana van Heemst
CONTEXT: With age, the prevalence of subclinical hypothyroidism rises. However, incidence and determinants of spontaneous normalization remain largely unknown. OBJECTIVE: To investigate incidence and determinants of spontaneous normalization of TSH levels in older adults with subclinical hypothyroidism. DESIGN: Pooled data were used from the (1) pretrial population and (2) in-trial placebo group from 2 randomized, double-blind, placebo-controlled trials (Thyroid Hormone Replacement for Untreated Older Adults With Subclinical Hypothyroidism Trial and Institute for Evidence-Based Medicine in Old Age thyroid 80-plus thyroid trial)...
February 20, 2024: Journal of Clinical Endocrinology and Metabolism
#33
JOURNAL ARTICLE
Iker Gómez-García, Alfredo Fernández-Quintela, María Puy Portillo, Jenifer Trepiana
Natural bioactive compounds have attracted a great deal of attention since some of them can act as thermogenesis activators. In recent years, special interest has been placed on resveratrol and its analogue pterostilbene, a dimethylether derivative that shows higher bioavailability. The aim of the present study is to compare the effects of resveratrol and its derivative pterostilbene on the thermogenic capacity of interscapular brown adipose tissue (iBAT) in rats under a high-fat high-fructose diet. Rats were divided into four experimental groups: control, high-fat high-fructose diet (HFHF) and HFHF diet supplemented with 30 mg/kg body weight/day of pterostilbene (PT30) or resveratrol (RSV30), for eight weeks...
October 16, 2023: Journal of Physiology and Biochemistry
#34
JOURNAL ARTICLE
Gustavo Henrique De Puy E Souza, Luciana Diniz Silva, Diego Alves Vieira, Gifone Aguiar Rocha, Agnaldo Soares Lima, Paula Vieira Teixeira Vidigal
•HDL cholesterol levels <60 mg/dL were independently associated with necroinflammatory activity in chronic hepatitis C (CHC). •CHC patients with hypertension are at an increased risk of developing necroinflammatory activity. •In patients with CHC, liver fibrosis was independently associated with old age, steatosis, and HDL-C <60 mg/dL. •Triglycerides levels ≥150 mg/dL were associated with lobular inflammatory activity in patients with CHC. Background - Approximately 71 million people are chronically infected with hepatitis C virus (HCV) worldwide...
2023: Arquivos de Gastroenterologia
#35
JOURNAL ARTICLE
Puying Li, Yajie Hu, Wenya He, Bing Lu, Haiyan Wang, Huhu Cheng, Liangti Qu
Constant water circulation between land, ocean and atmosphere contains great and sustainable energy, which has been successfully employed to generate electricity by the burgeoning water-enabled electric generator. However, water in various forms (e.g. liquid, moisture) is inevitably discharged after one-time use in current single-stage water-enabled electric generators, resulting in the huge waste of inherent energy within water circulation. Herein, a multistage coupling water-enabled electric generator is proposed, which utilizes the internal liquid flow and subsequently generated moisture to produce electricity synchronously, achieving a maximum output power density of ~92 mW m-2 (~11 W m-3 )...
September 14, 2023: Nature Communications
#36
JOURNAL ARTICLE
Cyril Aumar, Philippe Labazuy, Solène Buvat, Emmanuel Delage
The present Self-Potential (SP) dataset acquired in the Chaîne des Puys is the result of four decades of measurements carried out by master's students, PhD students, researchers, and engineering offices under the auspices of the Laboratoire Magmas et Volcans (LMV) and the Observatoire de Physique du Globe de Clermont-Ferrand (OPGC) . Acquired in the 1980s by Maurice Aubert and his collaborators (e.g. [1], [2], [3]), this Self-Potential dataset was completed as part of the CAPRICE project focused on the hydrosystem of the Chaîne des Puys...
October 2023: Data in Brief
#37
JOURNAL ARTICLE
P A Bahamonde, G Chiang, G Mancilla, T Contador, C Quezada-Romegialli, K Munkittrick, C Harrod
Salmonids were first introduced to Chilean freshwaters in the 1880s and approximately 140 years later, they are ubiquitous across Chilean rivers, especially in southern pristine freshwaters. This study examines the brown trout (Salmo trutta) and native taxa ecology in two adjacent, but contrasting rivers Chilean Patagonia. During Spring of 2016 and Spring-Fall 2017 we examined variation in benthic macroinvertebrate and fish community composition, characterised fish size structure, stomach contents, and stable isotopes (δ13 C and δ15 N) to understand population structure, fish diet and trophic interactions between S...
September 11, 2023: Journal of Fish Biology
#38
JOURNAL ARTICLE
Berk Taskin, Tia C L Kohs, Joseph J Shatzel, Cristina Puy, Owen J T McCarty
PURPOSE OF REVIEW: This review summarizes the pathophysiology and potential therapeutic options for treatment of multiple sclerosis, a common neuronal demyelinating disorder affecting 2.2 million people worldwide. As an autoimmune disorder, multiple sclerosis is associated with neuroinflammation and increased permeability of the blood-brain barrier (BBB), although the cause linking multiple sclerosis with compromised barrier function remains ill-defined. It has been previously shown that coagulation factors, including thrombin and fibrin, exacerbate the inflammatory processes and permeability of the BBB...
September 6, 2023: Current Opinion in Hematology
#39
JOURNAL ARTICLE
Iria Cabo-Lopez, Alfredo Puy-Nuñez, Nuria Redondo-Rafales, Sara Teixeira Baltazar, Beatriz Calderón-Cruz
BACKGROUND: Different screening tools to identify advanced Parkinson's disease (APD) have emerged in recent years. Among them, wearable medical devices, such as STAT-ON™, have been proposed to help to objectively detect APD. OBJECTIVES: To analyze the correlation between STAT-ON™ reports and other assessment tools to identify APD and to assess the accuracy of screening tools in APD patients, using the STAT-ON™ as the gold standard. METHODS: In this retrospective, observational study, data from the University Hospital Complex of Pontevedra database on 44 patients with potential APD who wore STAT-ON™ were extracted...
2023: Frontiers in Neurology
#40
JOURNAL ARTICLE
Antoine Poli, Hana Manceau, Anvi Laetitia Nguyen, Boualem Moulouel, Nathalie Dessendier, Neila Talbi, Hervé Puy, Christophe Junot, Laurent Gouya, Caroline Schmitt, Thibaud Lefebvre
BACKGROUND: The quantification of delta-aminolevulinic acid (ALA) and porphobilinogen (PBG) in urine are the first-line tests for diagnosis and monitoring of acute hepatic porphyrias (AHP). Ion-exchange chromatography (IEC), which is time- and staff-consuming and limited to urine, is still the preferred method in many specialized laboratories, despite the development of mass spectrometry-based methods. METHODS: We describe a new LC-MS method that allows for rapid and simple quantification of ALA and PBG in urine and plasma with an affordable instrument that was used to analyze 2260 urine samples and 309 blood samples collected in 2 years of routine activity...
August 22, 2023: Clinical Chemistry
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
