Panpan He, Huan Li, Yuanyuan Zhang, Tengfei Lin, Yun Song, Chengzhang Liu, Min Liang, Jing Nie, Binyan Wang, Huiyuan Guo, Xiaobin Wang, Yong Huo, Hao Zhang, Xiping Xu, Xianhui Qin
OBJECTIVE: We aimed to evaluate the association between baseline plasma zinc and the development of proteinuria as well as possible effect modifiers in hypertensive patients. METHODS: This is a subset of the China Stroke Primary Prevention Trial (CSPPT) Renal Sub-Study. In the CSPPT, participants were randomized to receive a daily oral dose of 1 tablet containing 10 mg enalapril and 0.8 mg folic acid or 1 tablet containing 10 mg enalapril only. A total of 783 participants with plasma zinc measurements and without proteinuria at baseline were included in the current study...
April 2, 2021: Journal of Trace Elements in Medicine and Biology