Jennifer Cane, Nicholas Sanderson, Sophie Barnett, Ali Vaughan, Megan Pott, Natalia Kapel, Marcus Morgan, Gerald Jesuthasan, Reggie Samuel, Muhammad Ehsaan, Hugh Boothe, Eric Haduli, Ruth Studley, Emma Rourke, Ian Diamond, Tom Fowler, Conall Watson, Nicole Stoesser, Ann Sarah Walker, Teresa Street, David Eyre
OBJECTIVES: We evaluated Nanopore sequencing for influenza surveillance. METHODS: Influenza A and B PCR-positive samples from hospital patients in Oxfordshire, UK, and a UK-wide population survey from winter 2022-23 underwent Nanopore sequencing following targeted rt-PCR amplification. RESULTS: From 941 infections, successful sequencing was achieved in 292/388(75%) available Oxfordshire samples: 231(79%) A/H3N2, 53(18%) A/H1N1, and 8(3%) B/Victoria and in 53/113(47%) UK-wide samples...
April 29, 2024: Journal of Infection