keyword
https://read.qxmd.com/read/38535030/trends-in-preoperative-airway-assessment
#1
REVIEW
Ioan Florin Marchis, Matei Florin Negrut, Cristina Maria Blebea, Mirela Crihan, Alexandru Leonard Alexa, Caius Mihai Breazu
Airway management is a vital part of anesthesia practices, intensive care units, and emergency departments, and a proper pre-operative assessment can guide clinicians' plans for securing an airway. Complex airway assessment has recently been at the forefront of anesthesia research, with a substantial increase in annual publications during the last 20 years. In this paper, we provide an extensive overview of the literature connected with pre-operative airway evaluation procedures, ranging from essential bedside physical examinations to advanced imaging techniques such as ultrasound (US), radiography, computed tomography (CT), and magnetic resonance imaging (MRI)...
March 13, 2024: Diagnostics
https://read.qxmd.com/read/38535022/fatal-deterioration-of-a-respiratory-syncytial-virus-infection-in-an-infant-with-abnormal-muscularization-of-intra-acinar-pulmonary-arteries-autopsy-and-histological-findings
#2
Nunzio Cosimo Mario Salfi, Gianluca Vergine, Maurizio Poloni, Sara Metalli, Barbara Bigucci, Francesca Facondini, Gianmatteo Pedrazzi, Francesca Masciopinto, Laura Bernabè, Vittorio Sambri, Maria Paola Bonasoni
Respiratory syncytial virus (RSV) infection represents a global and noteworthy cause of hospitalization and death in infants of less than 1 year of age. The typical clinical manifestation is bronchiolitis, an inflammatory process of the small airways. The symptoms are usually a brief period of low-grade fever, cough, coryza, breathing difficulties, and reduced feeding. The progression of the disease is difficult to predict, even in previous healthy subjects. Symptoms may also be subtle and underestimated, thus leading to sudden unexpected infant death (SUID)...
March 12, 2024: Diagnostics
https://read.qxmd.com/read/38534892/mastering-sedation-and-associated-respiratory-events-through-simulation-based-training-a-randomised-controlled-trial-involving-non-anaesthesiology-residents
#3
JOURNAL ARTICLE
Jean-Noël Evain, Tran Do, Hakim Harkouk, Pierre Drolet, Roger Perron, Mihai Georgescu, Arnaud Robitaille, Issam Tanoubi
Non-anaesthetists commonly administer procedural sedation worldwide, posing the risk of respiratory events that can lead to severe complications. This study aimed to evaluate whether simulation-based learning could lead to enhancements in the clinical proficiency of non-anaesthesiology residents in managing sedation and related respiratory complications. Following the evaluation of baseline clinical performance through a pre-test simulation, 34 residents were randomly allocated to either participate in an innovative simulation-based learning module (intervention group) or view a brief self-learning video (control group)...
February 23, 2024: European journal of investigation in health, psychology and education
https://read.qxmd.com/read/38534776/the-influence-of-neurotrophins-on-the-brain-lung-axis-conception-pregnancy-and-neonatal-period
#4
REVIEW
Federica D'Amico, Cecilia Lugarà, Giovanni Luppino, Carlo Giuffrida, Ylenia Giorgianni, Eleonora Maria Patanè, Sara Manti, Antonella Gambadauro, Mariarosaria La Rocca, Tiziana Abbate
Neurotrophins (NTs) are four small proteins produced by both neuronal and non-neuronal cells; they include nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). NTs can exert their action through both genomic and non-genomic mechanisms by interacting with specific receptors. Initial studies on NTs have identified them only as functional molecules of the nervous system. However, recent research have shown that some tissues and organs (such as the lungs, skin, and skeletal and smooth muscle) as well as some structural cells can secrete and respond to NTs...
March 15, 2024: Current Issues in Molecular Biology
https://read.qxmd.com/read/38534535/bio-inspired-magnetically-responsive-silicone-cilia-fabrication-strategy-and-interaction-with-biological-mucus
#5
JOURNAL ARTICLE
Aline Grein-Iankovski, Karina Andrighetti de Oliveira Braga, Daniel Formariz Legendre, Paulo Francisco Guerreiro Cardoso, Watson Loh
Cilia are biological structures essential to drive the mobility of secretions and maintain the proper function of the respiratory airways. However, this motile self-cleaning process is significantly compromised in the presence of silicone tracheal prosthesis, leading to biofilm growth and impeding effective treatment. To address this challenge and enhance the performance of these devices, we propose the fabrication of magnetic silicone cilia, with the prospect of their integration onto silicone prostheses. The present study presents a fabrication method based on magnetic self-assembly and assesses the interaction behavior of the cilia array with biological mucus...
March 7, 2024: Bioengineering
https://read.qxmd.com/read/38534377/granular-insights-neutrophil-predominance-and-elastase-release-in-severe-asthma-exacerbations-in-a-pediatric-cohort
#6
JOURNAL ARTICLE
Kirstin Henley, Erin Tresselt, Jessica S Hook, Parth A Patel, Michelle A Gill, Jessica G Moreland
The chronic inflammatory component of asthma is propagated by granulocytes, including neutrophils and eosinophils, in the peripheral circulation and airway. Previous studies have suggested that these cells have an altered expression of adhesion-related molecules and a propensity for the release of granule contents that may contribute to tissue damage and enhance inflammatory complications in patients with status asthmaticus. The goal of this prospective cohort study at a tertiary care pediatric hospital with a large population of asthma patients was to assess the role of granulocyte-based inflammation in the development of asthma exacerbation...
March 18, 2024: Cells
https://read.qxmd.com/read/38534319/exploring-the-potential-role-of-metabolomics-in-copd-a-concise-review
#7
REVIEW
Claudio Tirelli, Sabrina Mira, Luca Alessandro Belmonte, Federica De Filippi, Mauro De Grassi, Marta Italia, Sara Maggioni, Gabriele Guido, Michele Mondoni, Giorgio Walter Canonica, Stefano Centanni
Chronic Obstructive Pulmonary Disease (COPD) is a pathological condition of the respiratory system characterized by chronic airflow obstruction, associated with changes in the lung parenchyma (pulmonary emphysema), bronchi (chronic bronchitis) and bronchioles (small airways disease). In the last years, the importance of phenotyping and endotyping COPD patients has strongly emerged. Metabolomics refers to the study of metabolites (both intermediate or final products) and their biological processes in biomatrices...
March 7, 2024: Cells
https://read.qxmd.com/read/38534284/does-miniscrew-assisted-rapid-palatal-expansion-influence-upper-airway-in-adult-patients-a-scoping-review
#8
REVIEW
Mariachiara Benetti, Luca Montresor, Daniele Cantarella, Nicoletta Zerman, Enrico Spinas
(1) Objective: This scoping review evaluates the effects of miniscrew-assisted rapid palatal expansion (MARPE) on different regions of the upper airway in adult patients and investigates various methods of measurement. (2) Methods: The search encompassed Pubmed, Cochrane Library, Scopus and Web of Science. This review was conducted following the PRISMA_ScR guidelines, and the inclusion criteria for examined studies were chosen in accordance with the PICOS framework. (3) Results: Seven studies were included in this review, comprising four retrospective studies, one prospective and two case reports...
March 1, 2024: Dentistry Journal
https://read.qxmd.com/read/38534164/conservative-airway-management-successful-in-majority-of-infants-with-pierre-robin-sequence-at-queensland-children-s-hospital-a-retrospective-review
#9
JOURNAL ARTICLE
Harrison Theile, Yun Phua, Stuart Bade, Susan O'Mahony, Jasneek Chawla, Sadasivam Suresh, Richard Theile
PURPOSE: Pierre-Robin Sequence (PRS) is a congenital abnormality characterized by micrognathia, glossoptosis, and variable severity upper airway obstruction. Clear management algorithms are lacking, particularly the indications for surgical versus nonsurgical intervention. The authors reviewed the management of these children in Queensland. METHODS: All children diagnosed with PRS at Queensland Children's Hospital from April 2014 to October 2019 were identified (n=45), and their charts were retrospectively reviewed...
March 27, 2024: Journal of Craniofacial Surgery
https://read.qxmd.com/read/38533918/effects-of-increasing-sensitizing-doses-of-ovalbumin-on-airway-hyperresponsiveness-in-asthmatic-mice
#10
JOURNAL ARTICLE
Yan-Jiao Chen, Yu Yuan, Lu Peng, Xin-Yi Dong, Yu-Dong Xu, Yu Wang, Yong-Qing Yang
BACKGROUND: The dosage of ovalbumin (OVA) during the sensitization stage is considered a crucial factor in the development of airway hyperresponsiveness (AHR). However, the inconsistent dosages of sensitizing OVA used in current studies and the lack of research on their impact on AHR are notable limitations. METHODS: We examined the impact of increasing sensitizing doses of OVA in a murine asthma model, which entailed initial sensitization with OVA followed by repeated exposure to OVA aerosols...
March 2024: Immunity, Inflammation and Disease
https://read.qxmd.com/read/38533354/history-of-pollutant-adjuvants-in-respiratory-allergy
#11
REVIEW
Dennis Shusterman
Combined exposures to allergens and air pollutants emerged as a topic of concern in scientific circles by the 1980's, when it became clear that parallel increases in respiratory allergies and traffic-related air pollution had been occurring during the 20th century. Although historically there has been a tendency to treat exposure-related symptoms as either allergic or toxicologic in nature, cross-interactions have since been established between the two modalities. For example, exposure to selected air pollutants in concert with a given allergen can increase the likelihood that an individual will become sensitized to that allergen, strongly suggesting that the pollutant acted as an adjuvant ...
2024: Front Allergy
https://read.qxmd.com/read/38533169/from-pansinusitis-to-cerebritis-due-to-eikenella-corrodens
#12
Adriana América Silva, Inês Zão, João A Louro, Eduarda Pereira, Elisabete Monteiro
Meningitis is a rare but possible complication of sinusitis. We present a case of a 21-year-old woman with a history of fever, headache and nasal obstruction who presented at the emergency department with psychomotor agitation. Orotracheal intubation and invasive mechanical ventilation were given to protect airway. Blood analysis showed leukocytosis and elevated C-reactive protein. Cerebral and maxillofacial computed tomography (CT) demonstrated pansinusitis with gas foci more prominent in the left frontal sinus with an area of ​​bone rarefaction on the posterior wall with possible communication with the cranial cavity...
February 2024: Curēus
https://read.qxmd.com/read/38532934/case-report-bronchoscopic-intervention-for-rare-benign-airway-tumors-a-report-of-4-cases-and-literature-review
#13
Zhifang Cui, Jinhong Wang, Hongwu Wang, Lei Li, Xiaohui Si, Yanbin Zhang, Heng Zou
Due to their unique location, airway tumors have a significant impact on patient quality of life and survival. Current research has focused extensively on malignant airway tumors; however, benign airway tumors, especially rare ones, are less understood due to their low incidence. These tumors are often misdiagnosed and mistreated due to diagnostic challenges. Therefore, there is still a lack of consensus on the treatment of some rare benign airway tumors. Our center summarizes the diagnosis and treatment of four rare cases of benign airway stenosis in recent years, highlighting the bronchoscopic manifestations and therapeutic approaches to improve the understanding of these diseases...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38532759/closure-of-tb-pulmonary-cavern-using-endobronchial-valve-placement
#14
Teona Mskhaladze, David Tchkonia, Kakha Vacharadze, Nana Kiria, Mikolay Chkonia
INTRODUCTION: Enhancing the efficacy of treatment for Multi-Drug Resistant (MDR) and Extensively Drug Resistant (XDR) Tuberculosis has prompted exploration into adjunctive therapies, such as Endobronchial Valve Placement (EVP) in addition to pharmacological interventions. MATERIALS AND METHODS: EVP was performed utilizing a combination of rigid and flexible bronchoscopes to address airway hemorrhage and facilitate closure of TB cavities. The procedure involved the deployment of large valves (12 mm and 17 mm), necessitating the utilization of a rigid bronchoscope...
March 2024: Oxford Medical Case Reports
https://read.qxmd.com/read/38532483/ct-comparison-of-the-nasal-airway-anterior-and-posterior-to-the-piriform-aperture-in-patients-with-and-without-nasal-obstruction
#15
JOURNAL ARTICLE
Helen Heppt, Gerlig Widmann, Felix Riechelmann, Annette Runge, Herbert Riechelmann, Aris I Giotakis
BACKGROUND: Nasal airway stenosis may lie anterior and/or posterior to the piriform aperture. We intended to compare the nasal airway anterior and posterior to the piriform aperture in patients with and without nasal obstruction. METHODS: Segmented computed tomography cross-sectional areas of the nasal airway anterior (CT-CSAant ) and posterior to the piriform aperture (at the level of the head of the inferior turbinate; CT-CSApost ) were compared between patients with nasal obstruction (cases) and trauma controls...
March 27, 2024: Head & Face Medicine
https://read.qxmd.com/read/38532405/lung-transcriptomics-reveals-the-underlying-mechanism-by-which-aerobic-training-enhances-pulmonary-function-in-chronic-obstructive-pulmonary-disease
#16
JOURNAL ARTICLE
Jian Li, Cai-Tao Chen, Peijun Li, Xiaoyun Zhang, Xiaodan Liu, Weibing Wu, Wei Gu
BACKGROUND: Aerobic training is the primary method of rehabilitation for improving respiratory function in patients with chronic obstructive pulmonary disease (COPD) in remission. However, the mechanism underlying this improvement is not yet fully understood. The use of transcriptomics in rehabilitation medicine offers a promising strategy for uncovering the ways in which exercise training improves respiratory dysfunction in COPD patients. In this study, lung tissue was analyzed using transcriptomics to investigate the relationship between exercise and lung changes...
March 26, 2024: BMC Pulmonary Medicine
https://read.qxmd.com/read/38532376/efficacy-of-respiratory-rehabilitation-in-patients-with-covid-19-a-retrospective-study
#17
JOURNAL ARTICLE
Zhiyou Zhang, Congcong Wang, Zhendong Li, Yueyang Liu, Yutong Nie, Jianwei Zhang, Dawei Li
OBJECTIVE: The coronavirus disease 2019 (COVID-19) pandemic has resulted in millions of confirmed cases and deaths globally. The purpose of this study was to investigate the therapeutic effect of airway clearance technology combined with prone ventilation on patients infected with COVID-19. METHODS: 38 patients with COVID-19 (severe) who were treated in the intensive rehabilitation group of Shengli Oilfield Central Hospital. They were randomly divided into a control group and an observation group...
March 26, 2024: BMC Pulmonary Medicine
https://read.qxmd.com/read/38532193/correction-seven-years-on-from-the-canadian-airway-focus-group-difficult-airway-guidelines-an-observational-survey
#18
Malcolm Howard, Ruediger Noppens, Nelson Gonzalez, Philip M Jones, Sonja M Payne
No abstract text is available yet for this article.
March 26, 2024: Canadian Journal of Anaesthesia
https://read.qxmd.com/read/38532048/awake-pronation-with-helmet-cpap-in-early-covid-19-ards-patients-effects-on-respiratory-effort-and-distribution-of-ventilation-assessed-by-eit
#19
JOURNAL ARTICLE
Tommaso Fossali, Martina Locatelli, Riccardo Colombo, Alice Veronese, Beatrice Borghi, Elisabetta Ballone, Antonio Castelli, Roberto Rech, Emanuele Catena, Davide Ottolina
Prone positioning with continuous positive airway pressure (CPAP) is widely used for respiratory support in awake patients with COVID-19-associated acute respiratory failure. We aimed to assess the respiratory mechanics and distribution of ventilation in COVID-19-associated ARDS treated by CPAP in awake prone position. We studied 16 awake COVID-19 patients with moderate-to-severe ARDS. The study protocol consisted of a randomized sequence of supine and prone position with imposed positive end-expiratory pressure (PEEP) of 5 and 10 cmH2 O delivered by helmet CPAP...
March 26, 2024: Internal and Emergency Medicine
https://read.qxmd.com/read/38531753/comorbid-insomnia-and-sleep-apnea-challenges-and-treatments
#20
REVIEW
Kathleen M Sarber, Reena Dhanda Patil
Insomnia and obstructive sleep apnea (OSA) are 2 of the most prevalent sleep disorders and frequently co-occur. Cognitive behavioral therapy for insomnia is the first line treatment for insomnia and has been shown to improve compliance with positive airway pressure therapy. Other alternatives to OSA treatment may have higher acceptance in those with comorbid insomnia and sleep apnea (COMISA). Surgery, particularly hypoglossal nerve stimulation, appears to be well tolerated and may improve insomnia in those with COMISA...
March 26, 2024: Otolaryngologic Clinics of North America
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