Laura C Saunders, Guilhem J Collier, Ho-Fung Chan, Paul J C Hughes, Laurie J Smith, James Watson, James Meiring, Zoë Gabriel, Thomas Newman, Megan Plowright, Phillip Wade, James A Eaden, S Thomas, S Strickland, L Gustafsson, Jody Bray, Helen Marshall, David J Capener, Leanne Armstrong, Jennifer Rodgers, Martin Brook, Alberto M Biancardi, Madhwesha R Rao, Graham Norquay, Oliver Rodgers, Ryan Munro, James E Ball, Neil J Stewart, Allan Lawrie, Gisli Jenkins, James Grist, Fergus Gleeson, Rolf F Schulte, Kevin M Johnson, Frederick J Wilson, Anthony Cahn, Andrew J Swift, Smitha Rajaram, Gary H Mills, Lisa Watson, Paul J Collini, Rod Lawson, A A Roger Thompson, Jim M Wild
BACKGROUND: Microvascular abnormalities and impaired gas transfer have been observed in patients with COVID-19. The progression of pulmonary changes in these patients remains unclear. RESEARCH QUESTION: Do patients hospitalised due to COVID-19 without evidence of architectural distortion on structural imaging show longitudinal improvements in lung function measured using 1 H and 129 Xe magnetic resonance imaging between 6-52 weeks after hospitalisation? STUDY DESIGN AND METHODS: Patients who were hospitalised due to COVID-19 pneumonia underwent a pulmonary 1 H and 129 Xe MRI protocol at 6, 12, 25 and 51 weeks after hospital admission in a prospective cohort study between 11/2020 and 02/2022...
March 23, 2023: Chest