Jonathan I Witonsky, Jennifer R Elhawary, Celeste Eng, Sam S Oh, Sandra Salazar, Maria G Contreras, Vivian Medina, Elizabeth A Secor, Priscilla Zhang, Jamie L Everman, Ana Fairbanks-Mahnke, Elmar Pruesse, Satria P Sajuthi, Chih-Hao Chang, Tsunami Rosado Guerrero, Keyshla Canales Fuentes, Natalie Lopez, Chris Angely Montanez-Lopez, Richeliz Alfonso Otero, Raymarie Colon Rivera, Leysha Rodriguez, Gabriela Vazquez, Donglei Hu, Scott Huntsman, Nathan D Jackson, Yingchun Li, Andrew Morin, Natalie A Nieves, Cydney Rios, Gonzalo Serrano, Blake J M Williams, Elad Ziv, Camille M Moore, Dean Sheppard, Esteban Gonzalez Burchard, Max A Seibold, Jose R Rodriguez Santana
Epidemiologic studies demonstrate an association between early-life respiratory illnesses (RIs) and the development of childhood asthma. However, it remains uncertain whether these children are predisposed to both conditions or if early-life RIs induce alterations in airway function, immune responses, or other human biology that contribute to the development of asthma. Puerto Rican children experience a disproportionate burden of early-life RIs and asthma, making them an important population for investigating this complex interplay...
April 16, 2024: medRxiv