Samuele Ghezzo, Paola Mapelli, Carolina Bezzi, Ana Maria Samanes Gajate, Giorgio Brembilla, Irene Gotuzzo, Tommaso Russo, Erik Preza, Vito Cucchiara, Naghia Ahmed, Ilaria Neri, Sofia Mongardi, Massimo Freschi, Alberto Briganti, Francesco De Cobelli, Luigi Gianolli, Paola Scifo, Maria Picchio
PURPOSE: The aim of this study is to investigate the role of [68 Ga]Ga-PSMA-11 PET radiomics for the prediction of post-surgical International Society of Urological Pathology (PS ISUP) grade in primary prostate cancer (PCa). METHODS: This retrospective study included 47 PCa patients who underwent [68 Ga]Ga-PSMA-11 PET at IRCCS San Raffaele Scientific Institute before radical prostatectomy. The whole prostate was manually contoured on PET images and 103 image biomarker standardization initiative (IBSI)-compliant radiomic features (RFs) were extracted...
March 18, 2023: European Journal of Nuclear Medicine and Molecular Imaging