Heng Zhang, Jing-Jing Niu, Hao Zhou, Yi-Kai Hu, Wen-Can Li, Jian-Long Ma, Xin-Biao Liao, Kai-Jun Ma, Long Chen
AIM: To identify mtDNA and OGG1 as potential biomarker candidates for mechanical asphyxia. METHOD: The human tissues are divided into experimental group (hanging and strangulation) and control groups (hemorrhagic shock, brain injury group, and poisoning group). Detected the expression of OGG1 and integrity of mtDNA in cardiac tissue of each group. We used over-OGG1 vector and siRNA-OGG1 transfecting H9C2 cell line to observe the function of OGG1 in hypoxic cells...
May 30, 2024: Forensic Science International
Virginie Galais, Chris Gannicliffe, Patricia Dugard, Stephanie Wilson, Niamh Nic Daéid, Hervé Ménard
In forensic science, a robust and sound interpretation and evaluation of transferred fibre evidence requires an understanding of the principles and mechanisms that underpin fibre transfer, yet existing research lacks consistency and repeatability. This study investigates the impact of washing activities on both the release of fibres into wastewater and the transfer of constituent fibres from donor garments to receiver swatches. Using a low-cost friction tester and automated data collection through photography and ImageJ image processing software, controlled conditions were maintained for repeated experiments...
June 2, 2024: Forensic Science International
Mitra Abdollahi Diba, Vahid Sari Sarraf, Ramin Amirsasan, Saeid Dabbagh Nikoukheslat
BACKGROUND: High-calorie-expenditure training is common among endurance athletes and is an effective strategy for weight loss. Although many training protocols include walking, running, cycling, and swimming according to a target heart rate, there is limited research on high-calorie-expenditure interventions with multimodal training programs using quantitative methods. OBJECTIVE: The aims of this research protocol are to (1) develop a high-calorie-expenditure training program to cover target calorie expenditure according to the trainability of women classified as overweight (according to a BMI of 25-29...
June 13, 2024: JMIR Research Protocols
Szilard Laszlo Safran, David Follonier, Eric Weber, Petra Vayne-Bossert, Ulrike Ahrendts, Benno Rehberg-Klug
BACKGROUND: Pain assessment and proper evaluation of pain is a prerequisite for treatment of acute and chronic pain. Until now, most evaluations use only resting pain intensity and a unidimensional scale, although multidimensional pain assessment and especially assessment of functional pain impact on activities is recommended. The "Defense and Veterans Pain Rating Scale" (DVPRS) permits this multidimensional assessment, but no validated French translation exists. OBJECTIVES: To validate the French translation of the multidimensional DVPRS, called Functional Pain Scale (FPS) in multiple settings of acute and chronic pain...
June 13, 2024: Pain Medicine
Jiangke Tian, Yu Tang, Lijun Fan, Jing Liu, Xubai Qiao, Haiou Sun, Tianyuan Guo
OBJECTIVE: This study aims to evaluate the efficiency of ultrasound-guided core needle biopsy (CNB) and fine needle aspiration biopsy (FNA) in the diagnosis of breast cancer with internal mammary node (IMN) metastasis. The focus is on specimen satisfaction, puncture tolerance, and classification accuracy. METHODS: A retrospective analysis was conducted on breast cancer patients (n=106) who underwent ultrasound-guided IMN biopsy at our hospital from March 2020 to March 2023...
June 14, 2024: Alternative Therapies in Health and Medicine
Haojie Zhang, Xuehai Ma, Jinbiao Ye, Congzhi Liu, Zhiyang Zhou
CONTEXT: Degenerative spondylolisthesis (DS) is a prevalent degenerative condition affecting the lumbar spine. Local spinal parameters play a pivotal role in surgical complications and in the QoL that adults with spinal deformities experience. Treatment can effectively alleviate radicular symptoms, but it doesn't significantly mitigate postoperative axial symptoms (AS). OBJECTIVE: The study intended to investigate the correlation between postoperative axial symptoms (AS) and spinal-pelvic parameters for patients with DS of the lumbar spine...
June 14, 2024: Alternative Therapies in Health and Medicine
Mika T Lehto, Timo Kauppila, Hannu Kautiainen, Ossi Rahkonen, Merja K Laine, Kaisu Pitkälä
This is a register-based study that examines the distribution of diagnoses made by general practitioners (GPs) in the public primary health care of the city of Vantaa, Finland. Data were gathered from the electronic health record (EHR) system and consisted of every record entered into the EHR system between 1 January 2016 and 31 December 2018. Both absolute numbers and relative proportions of the 10th edition of International Classification of Diseases (ICD-10) diagnosis recordings were reported and calculated...
December 2024: International Journal of Circumpolar Health
Jim Berner, Solveig Jore, Khaled Abass, Arja Rautio
There is growing awareness and recognition of the importance of the One Health paradigm to address existing environmental threats and recognise emerging ones at an early stage among Arctic residents, public health agencies, and wildlife resource managers. The One Health approach, emphasising the interconnectedness of human, animal, and ecosystem health, plays a pivotal role in addressing these multifaceted issues. Warming climate and permafrost thaw may influence both contaminant exposure and the spread of zoonotic infectious diseases and have impacts on water and food security...
December 2024: International Journal of Circumpolar Health
Farima Said Ali-Samani, Arman Shahrisa, Maryam Tahmasebi-Birgani, Mohammadreza Hajjari, Pegah Ghandil
The World Health Organization has considered the infertility as an international public health problem. Infertility affect nearly 1 in 7 couples and male component contributes to 50% of infertility cases. There is a clear link between male infertility and some cancers such as testicular germ cell, prostate and colon cancers. Two possibilities support this finding: 1) Cancer treatments can affect the fertility factors 2) Genetic profile of infertility genes have been altered in cancer patients. Although the previously published researches have mostly focused on the first factor, no article has yet confirmed the role of genetic factors...
December 2024: Systems Biology in Reproductive Medicine
Hongzhou Liu, Song Dong, Hua Yang, Linlin Wang, Jia Liu, Yangfan Du, Jing Liu, Zhaohui Lyu, Yuhan Wang, Li Jiang, Shasha Yu, Xiaomin Fu
OBJECTIVE: To evaluate the effectiveness of machine learning (ML) models in predicting 5-year type 2 diabetes mellitus (T2DM) risk within the Chinese population by retrospectively analyzing annual health checkup records. METHODS: We included 46,247 patients (32,372 and 13,875 in training and validation sets, respectively) from a national health checkup center database. Univariate and multivariate Cox analyses were performed to identify factors influencing T2DM risk...
June 2024: Journal of International Medical Research
Ádám Ipkovich, Tímea Czvetkó, Lilibeth A Acosta, Sanga Lee, Innocent Nzimenyera, Viktor Sebestyén, János Abonyi
Model-based assessment of the potential impacts of variables on the Sustainable Development Goals (SDGs) can bring great additional information about possible policy intervention points. In the context of sustainability planning, machine learning techniques can provide data-driven solutions throughout the modeling life cycle. In a changing environment, existing models must be continuously reviewed and developed for effective decision support. Thus, we propose to use the Machine Learning Operations (MLOps) life cycle framework...
2024: PloS One
Manuel Muñoz-Rodríguez, Rosana Ferrero, Juan Pablo Luna, Mauricio Lima
On October 18, 2019, Chile experienced the most important social upheaval since the country regained democracy in the late 1980s. The "Social Outbreak" surprised economic and political elites and seemed paradoxical to the international community who had often praised Chile as a model of successful development. In this paper, we used structural-demographic theory to analyze the interaction between the overproduction of elites and the stagnation in the relative income of the population as the underlying structural cause of Chilean political instability...
2024: PloS One
Jonas Ngouhouo-Poufoun, Sabine Chaupain-Guillot, Youba Ndiaye, Denis Jean Sonwa, Kevin Yana Njabo, Philippe Delacote
In the context of emerging international trade regulations on deforestation-free commodities, the drivers of households' deforestation in conservation landscapes are of interest. The role of households' livelihood strategies including cocoa production, and the effects of human-elephant conflict are investigated. Using a unique dataset from a survey of 1035 households in the Tridom landscape in the Congo basin, the spatial autoregressive model shows that: (1) Households imitate the deforestation decisions of their neighbors; (2) A marginally higher income from cocoa production-based livelihood portfolios is associated with six to seven times higher deforestation compared to other livelihood strategies with a significant spillover effect on neighboring households' deforestation...
2024: PloS One
Abdullah Alalawi, Lindsay Blank, Elizabeth Goyder
BACKGROUND: Obesity and physical inactivity among children and young people are public health concerns. Despite the wide variety of interventions available to promote physical activity, little is known about which interventions are most effective. This review aimed to evaluate the existing literature on school-based interventions that aim to increase physical activity among children and young people aged 6 to 18 years. METHODS: A systematic review of reviews was undertaken...
2024: PloS One
Chengqiang Yin, Shourui Wang, Jie Gao
The article presents a unified control system designing scheme to obtain enhanced performance for processes including integrator and dead time. A simple control structure including two controllers is proposed. Servo performance and disturbance rejection performance can be adjusted independently by introducing a desired transfer function model in the control structure. Servo controller is designed according to the direct synthesis principle and disturbance rejection controller is derived adopting the internal model control (IMC) theory...
2024: PloS One
Christian Morgenstern, Daniel J Laydon, Charles Whittaker, Swapnil Mishra, David Haw, Samir Bhatt, Neil M Ferguson
BACKGROUND: The COVID-19 pandemic has caused over 7.02 million deaths as of January 2024 and profoundly affected most countries' Gross Domestic Product (GDP). Here, we study the interaction of SARS-CoV-2 transmission, mortality, and economic output between January 2020 and December 2022 across 25 European countries. METHODS: We use a Bayesian mixed effects model with auto-regressive terms to estimate the temporal relationships between disease transmission, excess deaths, changes in economic output, transit mobility and non-pharmaceutical interventions (NPIs) across countries...
2024: PloS One
Ashraf Mohammed Alhumaidi, Abdulrahman Ahmed Aseri, Manea Musa M Alahmari, Hafiz Ahmed Adawi, Khalid Aldhorae, Thrya S Gadah, Mohammed E Sayed, Nasser M Al Ahmari, Abdulelah Ali Daghriri, Abdulrahman H Alzahrani, Mohammed M Al Moaleem
BACKGROUND The nasopalatine canal (NPC), or incisive canal, is located in the midline of the palate, posterior to the maxillary central incisors. Its anatomy is important in prosthetic dentistry procedures. This study aimed to assess the anatomical morphology of the NPC according to age, sex, and dental status using cone-beam computed tomography (CBCT) in 335 patients. MATERIAL AND METHODS In this retrospective cross-sectional study, a total of 335 patients were recruited and categorized according to sex, age, and dental status...
June 13, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Melissa Mulraney, Umanga de Silva, Andria Joseph, Maria da Luz Sousa Fialho, Iain Dutia, Natalie Munro, Jonathan M Payne, Tobias Banaschewski, Cláudia Bandeira de Lima, Mark A Bellgrove, Samuel R Chamberlain, Phyllis Chan, Ivy Chong, Alison Clink, Samuele Cortese, Eileen Daly, Stephen V Faraone, Melissa Gladstone, Adam J Guastella, Juulia Järvdike, Sidra Kaleem, Mark G Lovell, Tamasin Meller, Peter Nagy, Jeffrey H Newcorn, Guilherme V Polanczyk, Emily Simonoff, Peter Szatmari, Caroline Tehan, Karin Walsh, Susan Wamithi, David Coghill
IMPORTANCE: The use of evidence-based standardized outcome measures is increasingly recognized as key to guiding clinical decision-making in mental health. Implementation of these measures into clinical practice has been hampered by lack of clarity on what to measure and how to do this in a reliable and standardized way. OBJECTIVE: To develop a core set of outcome measures for specific neurodevelopmental disorders (NDDs), such as attention-deficit/hyperactivity disorder (ADHD), communication disorders, specific learning disorders, and motor disorders, that may be used across a range of geographic and cultural settings...
June 3, 2024: JAMA Network Open
Megan C Best, Grahame Simpson, Kate F Jones, Frankie Merritt, Michael Casey, Sandra Lynch, John A Eisman, Jeffrey Cohen, Darryl Mackie, Kirsty Beilharz, Matthew Kearney
Spiritual wellbeing is known to be a predictor of increased patient coping in hospital settings. Therefore, access to a valid and reliable measure of spiritual wellbeing amongst general hospital patients is highly recommended. The aim of this study was to investigate the dimensionality, reliability, and validity of the Functional Assessment of Chronic Illness Therapy Spiritual Wellbeing scale (FACIT-Sp-12) in a heterogeneous cohort of hospital patients. A cross-sectional survey was administered to 897 adult patients across six hospitals in Sydney, Australia...
June 13, 2024: Journal of Religion and Health
R Anitha, K C John, G Jabarethina
Robotic surgery (RS) is a milestone in minimally invasive surgery. More than 500 surgeons are trained in RS in India, and more than 100 robotic systems have been installed across various centers. RS offers various benefits to patients and surgeons. Although it is rapidly advancing and has several advantages, a robotic system is a complex system that is equipped with complex instruments. Qualitative research aims to take a broad view of the perceptions of stakeholders of RS and to synthesize their views to gain insight into scaling RS...
June 13, 2024: Journal of Robotic Surgery
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