Stef Feijen, Angela Tate, Kevin Kuppens, Lorna A Barry, Filip Struyf
The high incidence of injury during swim-training as well as the increasing demands of the sports make monitoring of the swimmer's training load a key concept requiring further investigation. Research has previously introduced numerous methods for the purposes of monitoring the swimmer's training load, but a narrative review discussing the strengths and limitations of each method is lacking. Consequently, this narrative review aims to summarize the monitoring strategies that have been applied in sports medicine research on competitive swimmers...
August 7, 2020: Scandinavian Journal of Medicine & Science in Sports
A De Giorgi, F Fabbian, E Di Simone, S Greco, R De Giorgio, G Zuliani, A Passaro, E Caselli, R Manfredini
OBJECTIVE: At the end of 2019, the Novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), spread rapidly from China to the whole world. Circadian rhythms can play crucial role in the complex interplay between viruses and organisms, and temporized schedules (chronotherapy) have been positively tested in several medical diseases. We aimed to compare the possible effects of a morning vs. evening antiviral administration in COVID patients. PATIENTS AND METHODS: We retrospectively evaluated all patients admitted to COVID internal medicine units with confirmed SARS-CoV-2 infection, and treated with darunavir-ritonavir (single daily dose, for seven days)...
August 2020: European Review for Medical and Pharmacological Sciences
J P Das, N Thulasidasan, I Ahmed, A Diamantopoulos
PURPOSE: Bibliometric analysis is a quantitative assessment of the academic literature in a particular field. The aim of our study was to characterize the 100 top-cited articles regarding transarterial chemoembolization (TACE) for the treatment of hepatocellular carcinoma (HCC). MATERIALS AND METHODS: The 'Web of Science' database was used to identify the leading articles regarding TACE for HCC. We determined the top 100 articles according to citations and performed an analysis on year of publication, authorship, department affiliation, publishing journal, institution and country of origin, subject matter and article type...
August 7, 2020: Japanese Journal of Radiology
Lorenzo Falsetti, Marianna Martino, Vincenzo Zaccone, Giovanna Viticchi, Alessia Raponi, Gianluca Moroncini, Agnese Fioranelli, Chiara di Pentima, Alessandro Martini, Cinzia Nitti, Aldo Salvi, Maurizio Burattini, Nicola Tarquinio
PURPOSE: To reduce intensive care unit overcrowding and optimize resources, elderly patients affected by suspected infection with declining clinical conditions could be managed in internal medicine departments with stepdown beds. However, commonly used prognostic scores, as Sequential Organ Failure Assessment (SOFA) or quick SOFA (qSOFA) have never been studied in this specific setting. The aim of this study was to evaluate the role and the accuracy of SOFA and qSOFA as prognostic scores in a population of elderly patients with suspected infection admitted to stepdown beds of two internal medicine departments...
August 6, 2020: Infection
James F Schwartz, Anthony R Artino, Ting Dong
INTRODUCTION: The Uniformed Services University of the Health Sciences coordinates a 2-week Summer Operational Experience (SOE) during the first year of medical school. The SOE aims to provide students with operational context and enhance familiarity with service-specific operational environments, the services' medical department capabilities, and/or general warfighter skills. One overarching goal of the SOE is to provide an experience that may motivate students to pursue an operational medicine assignment at some point in their military career...
August 6, 2020: Military Medicine
Carlo Gotti, Alberto Sensini, Gianmaria Fornaia, Chiara Gualandi, Andrea Zucchelli, Maria Letizia Focarete
Skeletal muscles are considered to date the best existing actuator in nature thanks to their hierarchical multiscale fibrous structure capable to enhance their strength and contractile performances. In recent years, driven by the growing of the soft robotics and tissue-engineering research field, many biomimetic soft actuators and scaffolds were designed by taking inspiration from the biological skeletal muscle. In this work we used the electrospinning technique to develop a hierarchically arranged nanofibrous structure resembling the morphology and passive biomechanical properties of skeletal muscles...
2020: Frontiers in Bioengineering and Biotechnology
Houli Li, Benjie Wang, Guiyan Yuan, Xiaoyan Liu, Jing Huang, Lilong Xiong, Di Zhang, Weiyi Feng, Ruichen Guo
Bushen Pills (BSPs), as a traditional Chinese medicine (TCM), is widely used in clinic to enrich Yang, nourish Yin, stem essence, and strengthen kidneys. Two chromatographic methods, liquid chromatography-mass spectrometry (LC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS), were applied to analyze the multiple active components of BSPs in dosage form for quality evaluation and in rat plasma for pharmacokinetics study, respectively. Three active constituents of BSPs, including paeoniflorin (PF), berberine hydrochloride (BBR), and schizandrin (SCH), were simultaneously determined by the established LC-MS method with electrospray ionization (ESI) in positive selected ion monitoring (SIM) mode at m / z 503...
2020: Journal of Analytical Methods in Chemistry
Abeer Salem Al Shahrani
BACKGROUND: Evidence-based medicine (EBM) is a core competence in both undergraduate and postgraduate medical curricula. However, its integration into curricula varies widely. Our study will help medical colleges develop, implement and evaluate their EBM courses. We assessed the effectiveness of workshops in improving critical appraisal skills among medical students. METHODS: A before-and-after study design without a control group was used. A 5-week short EBM module including lectures, workshops, and online search sessions was conducted with 52 fourth-year medical students during their primary healthcare course at the College of Medicine, Princess Nourah bint Abdulrahman University...
August 6, 2020: BMC Medical Education
Oraib Abdallah, Rwedah Anwar Ageeb, Wishah Hamza Imam Elkhalifa, Monica Zolezzi, Alla El-Awaisi, Mohammad Issam Diab, Ahmed Awaisu
BACKGROUND: The objective of this study was to evaluate the existing Bachelor of Science in Pharmacy [BSc (Pharm)] curriculum at Qatar University College of Pharmacy (QU CPH), for addressing international prescribing competencies. METHODS: The Australian National Prescribing Service (NPS MedicineWise) Competencies Required to Prescribe Medicines framework (the Prescribing Competencies Framework) was used in the BSc (Pharm) curriculum mapping process. The NPS MedicineWise Prescribing Competencies Framework outlines seven competency areas that are essential for pharmacist prescribing...
August 6, 2020: BMC Medical Education
Huizheng Wang, Shilong Wang, Yubin Lan
Celtis sinensis Pers. (Chinese hackberry), belonging to the family Ulmaceae, is widely used as a street tree or landscape plant because of its longevity and aesthetic growth habit. Additionally, C. sinensis is of economic importance due to its medicinal properties. Roots and bark of the plant can be used in natural medicine for the treatment of lumbago, measles, tumor, etc (Zhang et al. 2016). In July 2019, symptoms of leaf spot were observed on C. sinensis in Yuanshan national forest park of Zibo, Shandong Province, China (36...
August 6, 2020: Plant Disease
Natalia García-Vazquez, Samara Palma Milla, Bricia López Plaza, Marlhyn Valero-Pérez, Marina Morato-Martínez, Carmen Gómez Candela
INTRODUCTION: disease-related malnutrition (DRM) is a specific type of malnutrition caused by the inflammatory response to the underlying disease. Its prevalence worldwide varies from 30 % to 50 %, being similar in Spanish hospitals. DRE is not commonly recognized but is usually misdiagnosed and generally not treated. It is associated with an increased risk of morbidity, mortality, and costs. Nutritional societies recommend that screening be performed within the first 24 to 48 hours after admission for the early detection of malnutrition...
August 7, 2020: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
James A Lipton, Jordann E Kokoski, Arianna T Lipton
The authors present the case of a 24-year-old man who sustained multiple injuries during a hard landing following a parachute jump. These injuries included a right sacral fracture, bilateral femoral fractures, a separated pubic symphysis, and compression fractures of the fifth and sixth thoracic vertebrae. He was treated with a right sacroiliac joint fixation, pubic symphysis fixation, open reduction internal fixation of his bilateral femurs, and fusion of the third through seventh thoracic vertebrae. The patient experienced back pain, bilateral hip pain, and bilateral knee pain resistant to chiropractic and medical treatments...
August 5, 2020: Journal of the American Osteopathic Association
Laila A Gharzai, Kenneth Resnicow, Lawrence C An, Reshma Jagsi
Importance: The novel coronavirus disease 2019 (COVID-19) pandemic has dramatically changed the US health care system, causing an influx of patients who require resources. Many oncologists are having challenging conversations with their patients about how the COVID-19 pandemic is affecting cancer care and may desire evidence-based communication guidance. Objectives: To identify the clinical scenarios that pose communication challenges, understand patient reactions to these scenarios, and develop a communication guide with sample responses...
August 6, 2020: JAMA Oncology
Muralikrishna Konda, Balasunder Dodda, Venu Madhav Konala, Srikanth Naramala, Sreedhar Adapa
Coronavirus disease 2019 (COVID-19) is an emerging infectious disease that has resulted in a global pandemic and is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Zoonotic diseases are infections that are transmitted from animals to humans. COVID-19 caused by SARS-CoV-2 most likely originated in bats and transmitted to humans through a possible intermediate host. Based on published research so far, pangolins are considered the most likely intermediate hosts. Further studies are needed on different wild animal species, including pangolins that are sold at the same wet market or similar wet markets before concluding pangolins as definitive intermediate hosts...
June 30, 2020: Curēus
Viktor V Horodovenko, Vitalii M Pashkov, Larysa G Udovyka
OBJECTIVE: Introduction: A rapid development of biomedicine, genetics, pharmacology, transplantation and biotechnology has posed a number of problems to humanity, in particular, with regard to human rights protection in healthcare. These problems solution requires considering the achievements and propositions of biology, medicine, ethics and law. International legal standards in the field of bioethics are of significance in development of national states regulations on bioethics and biotic legislation...
2020: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
Farouq Ahmad Faleh Alazzam, Ali Jabbar Saleh, Khaled Khalaf Abed Rabbo Aldrou
OBJECTIVE: The aim of the article is a theoretical and methodological justification for strengthening the role of international trade in medicines and equipment during the COVID-19 pandemic, to establish the benefits of free trade, to develop important international trade policy priorities in this field. PATIENTS AND METHODS: Materials and methods: Legislation of foreign countries and international organizations, statistical data published by international organizations are the materials of the research...
2020: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
Maria Sole Vallecoccia, Cristina Dominedò, Salvatore Lucio Cutuli, Ignacio Martin-Loeches, Antoni Torres, Gennaro De Pascale
INTRODUCTION: Nosocomial pneumonia develops after ≥48 h of hospitalisation and is classified as ventilator-associated pneumonia (VAP) and hospital-acquired pneumonia (HAP); the latter may require mechanical ventilation (V-HAP) or not (NV-HAP). MAIN FINDINGS: VAP and HAP affect a significant proportion of hospitalised patients and are characterised by poor clinical outcomes. Among them, V-HAP has the greatest 28-day mortality rate followed by VAP and NV-HAP (27...
September 30, 2020: European Respiratory Review: An Official Journal of the European Respiratory Society
Elie Azoulay, Jan de Waele, Ricard Ferrer, Thomas Staudinger, Marta Borkowska, Pedro Povoa, Katerina Iliopoulou, Antonio Artigas, Stefan J Schaller, Manu Shankar-Hari, Mariangela Pellegrini, Michael Darmon, Jozef Kesecioglu, Maurizio Cecconi
BACKGROUND: There is little evidence to support the management of severe COVID-19 patients. METHODS: To document this variation in practices, we performed an online survey (April 30-May 25, 2020) on behalf of the European Society of Intensive Care Medicine (ESICM). A case vignette was sent to ESICM members. Questions investigated practices for a previously healthy 39-year-old patient presenting with severe hypoxemia from COVID-19 infection. RESULTS: A total of 1132 ICU specialists (response rate 20%) from 85 countries (12 regions) responded to the survey...
August 5, 2020: Critical Care: the Official Journal of the Critical Care Forum
Jean-Yin Tan, Irene W Y Ma, Julie A Hunt, Grace P S Kwong, Robin Farrell, Catriona Bell, Emma K Read
The Objective Structured Clinical Examination (OSCE) is a valid, reliable assessment of veterinary students' clinical skills that requires significant examiner training and scoring time. This article seeks to investigate the utility of implementing video recording by scoring OSCEs in real-time using live examiners, and afterwards using video examiners from within and outside the learners' home institution. Using checklists, learners (n=33) were assessed by one live examiner and five video examiners on three OSCE stations: suturing, arthrocentesis, and thoracocentesis...
August 6, 2020: Journal of Veterinary Medical Education
Kelsey Isbester, Samuel Boas, Lesley Summerville, Corinne Wee, Anand Kumar
In 2014, payments to medical providers from drug/device manufacturers were made public through the Open Payments Database. Although previous studies have used the Open Payments Database to describe relationships between specialties and industry, few have evaluated specific companies and the effect of their contributions. As a large contributor to industry payments in plastic surgery, Allergan, Inc represents a significant source of potential financial conflicts of interest in the field. In this study, we aimed to describe the quantity, type, and specific products associated with Allergan's payments to both plastic surgeons and physicians of other specialties...
July 27, 2020: Annals of Plastic Surgery
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