Giulio Conte, John R Giudicessi, Michael J Ackerman
Prior to the recognition of distinct clinical entities, such as Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, and long QT syndrome, all sudden cardiac arrest (SCA) survivors with ventricular fibrillation (VF) and apparently structurally normal hearts were labelled as idiopathic ventricular fibrillation (IVF). Over the last three decades, the definition of IVF has changed substantially, mostly as result of the identification of the spectrum of SCA-predisposing genetic heart diseases (GHDs), and the molecular evidence, by post-mortem genetic analysis (aka, the molecular autopsy), of cardiac channelopathies as the pathogenic basis for up to 35% of unexplained cases of sudden cardiac death (SCD) in the young...
October 10, 2020: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Elsa Genzoni, Fabian Braun, Jerome Van Zaen, Philippe Renevey, Mathieu Lemay, Etienne Pruvot, Jean-Marc Vesin
Atrial fibrillation (AF) affects millions of people worldwide and needs to be diagnosed in its early stage to provide proper treatment. However, the numerous wearable devices available today are not yet able to discriminate AF episodes from other cardiac arrhythmias and merely detect normal vs abnormal rhythms.In this study we investigated the performance of a traditional classifier - designed to distinguish AF and sinus rhythm (SR) using inter-beat intervals (IBI) - when confronted with other - non-AF - arrhythmias...
July 2020: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Gita Gupta, Peter M Farrehi, Ronald D Chervin
No abstract text is available yet for this article.
June 20, 2020: Sleep Medicine
Louise Reilly, Francisco J Alvarado, Di Lang, Sara Abozeid, Hannah Van Ert, Cordell Spellman, Jarrett Warden, Jonathan C Makielski, Alexey V Glukhov, Lee L Eckhardt
BACKGROUND: Arrhythmia syndromes associated with KCNJ2 mutations have been described clinically; however, little is known of the underlying arrhythmia mechanism. We create the first patient inspired KCNJ2 transgenic mouse and study effects of this mutation on cardiac function, I K1 , and Ca2+ handling, to determine the underlying cellular arrhythmic pathogenesis. METHODS: A cardiac-specific KCNJ2 -R67Q mouse was generated and bred for heterozygosity (R67Q+/- ). Echocardiography was performed at rest, under anesthesia...
September 2020: Circulation. Arrhythmia and Electrophysiology
Laszlo Littmann, József Tenczer
One of the more common causes of bigeminy at the ventricular level is type 1 second-degree atrioventricular (AV) block with 3:2 conduction ratio. In 3:2 Wenckebach, the shorter cycles reflect the consecutively conducted impulses and the longer cycles coincide with the blocked P waves. Theoretically, however, depending on the degree of conduction delay between the first and second transmitted impulses, other types of spacing of the QRS complexes may become possible. In this retrospective study of 180 patients who underwent electrophysiologic studies for symptomatic arrhythmias, atrial pacing-induced 3:2 Wenckebach periodicity resulted in a regular ventricular rate and/or in "reverse bigeminy" in 16 cases (8...
August 15, 2020: Journal of Electrocardiology
Guadalupe Garcia Isla, Valentina D A Corino, Luca Mainardi
A detector based only on RR intervals capable of classifying other tachyarrhythmias in addition to atrial fibrillation (AF) could improve cardiac monitoring. In this paper a new classification method based in a 2D non-linear RRI dynamics representation is presented. For this aim, the concepts of Poincar Images and Atlases are introduced. Three cardiac rhythms were targeted: Normal sinus rhythm (NSR), AF and atrial bigeminy (AB). Three Physionet open source databases were used. Poincar images were generated for all signals using different Poincar plot configurations: RR, dRR and RRdRR...
July 28, 2020: IEEE Journal of Biomedical and Health Informatics
Masaaki Yokoyama, Seigo Yamashita, Michifumi Tokuda, Saagar Mahida, Michiiro Yoshimura, Teiichi Yamane
We present a case of a 67-year-old female with a previous history of a pulmonary vein isolation for paroxysmal atrial fibrillation who presented with supraventricular bigeminy with a constant coupling interval. The supraventricular bigeminy originated from the anterior mitral annulus with initial mapping suggestive of a focal mechanism. However detailed mapping using an ultra-high resolution mapping system (with manual shifting of the annotation window) revealed very low amplitude potentials connecting the previous sinus beat with continuous activation along the mitral annulus...
June 30, 2020: Journal of Cardiovascular Electrophysiology
Juan Benezet-Mazuecos, Álvaro Lozano Rosado, Julian Crosa
ECG of patients with Wolf Parkinson White (WPW) syndrome may simulate other entities such as myocardial infarction, ventricular premature complexes, ventricular bigeminy, accelerated idioventricular rhythm, intermittent bundle branch block or electrical alternans. On the other hand, the opposite can also occur where these other conditions may simulate WPW. We present the case of a young patient referred for WPW ablation showing an incessant accelerated idioventricular rhythm mimicking preexcitation.
July 2020: Journal of Electrocardiology
Quentin Voglimacci-Stephanopoli, Frederic Sacher, Claire Martin, Christian Meyer, Ruairidh Martin, Anne Rollin, Stefano Capellino, Pierre Mondoly, Franck Mandel, Pierre Jaïs, Maud Tabuteau, Philippe Maury
PURPOSE: Scars and abnormal electrograms may significantly differ according to the activation wavefront. We propose a new fast technique for reliable comparison between sinus rhythm and ventricular pacing using a single map acquisition and the Rhythmia™ 3D mapping system. METHODS: A special programming of the external stimulator was assuring full stable regular paced-beat bigeminy during spontaneous rhythm. A first map was acquired for the spontaneous cardiac beat...
June 19, 2020: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Arlene Te, Tzong-Yow Wu, Yen-Lin Chen, Dee Pei, Shu-Hsiang Liu, Yi-Ching Su, Chun-Hsien Hsu
No abstract text is available yet for this article.
June 8, 2020: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
Dimitrios Katsaras, Jonathan Ariyaratnam, Shajil Chalil, Khalid Abozguia
No abstract text is available yet for this article.
June 3, 2020: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Ashleigh Long, Paul Marik
Metastatic cancer that involves the structures of the heart is a rare complication and most commonly diagnosed during postmortem examination. Classically, the development of secondary tumors involves invasion of the pericardium or the myocardium and may disrupt the cardiac conduction system, causing new arrhythmias and heart failure. In this article, we present the case of a 58-year-old female with new diagnosis of ventricular bigeminy, and evidence of cardiac tamponade physiology from direct compression of the right ventricular outflow tract from high-grade carcinoma of the left breast...
January 2020: Journal of Investigative Medicine High Impact Case Reports
Benjamin A Teplitzky, Michael McRoberts, Hamid Ghanbari
BACKGROUND: Increasing utilization of long-term outpatient ambulatory electrocardiographic (ECG) monitoring continues to drive the need for improved ECG interpretation algorithms. OBJECTIVE: The purpose of this study was to describe the BeatLogic® platform for ECG interpretation and to validate the platform using electrophysiologist-adjudicated real-world data and publicly available validation data. METHODS: Deep learning models were trained to perform beat and rhythm detection/classification using ECGs collected with the Preventice BodyGuardian® Heart monitor...
May 2020: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Giacomo Mugnai, Gian-Battista Chierchia, Carlo de Asmundis, Pedro Brugada
The present case reports for the first time an unusual presentation of Brugada type 1 pattern occurring in a "bigeminy way" without no drug challenges or any apparent causes in a family member of a proband with type 1 pattern. This article is protected by copyright. All rights reserved.
April 3, 2020: Pacing and Clinical Electrophysiology: PACE
Harry G Mond, Haris M Haqqani
Ventricular ectopics, also known as ventricular extrasystoles, premature ventricular contractions or complexes (PVC) and ventricular premature depolarisations (VPD) are beats arising from within the ventricles. When they occur in groupings such as bigeminy, trigeminy, couplets and triplets they are referred to as ventricular ectopy. The electrocardiographic (ECG) footprints of a ventricular ectopic include a broad (>110 ms), premature, ventricular complex (QRS deflection); no evidence of pure atrioventricular (AV) conduction; a full, more than, or less than compensatory pause; and discordant QRS and T wave axis...
July 2020: Heart, Lung & Circulation
Balaram Krishna J Hanumanthu, Yashasvi Chugh, Michael Grushko, Robert T Faillace
The spectrum of electrocardiographic changes seen with hyperkalemia is known to progress gradually with increasing serum levels of potassium. Initial changes are limited to peaked T waves and QT shortening, which subsequently progress to prolonged QRS/QT intervals, and finally sinus arrest, sinus bradycardia and asystole. We report a unique case of severe sinus bradycardia with atrial bigeminy and junctional rhythm in the setting of moderate hyperkalemia, a rarely reported electrocardiographic finding.
December 21, 2019: Curēus
Samed Talibi, Craig Douglas, Benjamin Pope
This is a case report, which explores the presentation to the emergency department of a fit and well female with a known ventricular bigeminy. She presented with convulsive episodes. The working differential diagnosis was of possible cardiac syncope with anoxic seizure activity or neurogenically mediated arrhythmia secondary to subarachnoid haemorrhage. On further collateral history, the patient was on citalopram. The ECGs demonstrated PVCs of multiple morphologies that were transiently bidirectional, raising the possibility of catecholaminergic polymorphic ventricular tachycardia...
2020: Case Reports in Emergency Medicine
Ghena Hammour, Metin Yarici, Wilhelm von Rosenberg, Danilo P Mandic
Out-of-clinic, continuous monitoring of vital signs is envisaged to become the backbone of future e-health. The emerging wrist worn devices have already proven to be a success in the measurement of pulse, however, a susceptibility to artefacts and missing data caused by regular motion in everyday activities, and the inability to continuously acquire the electrocardiogram call into question the utility of this technology in future e-Health. With this in mind, the head, and in particular the ear canals, have been investigated as possible locations for wearable devices...
July 2019: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Dalton Argean Norwood, Lucia Belem Dominguez, Ricardo Leonel Dominguez, Walter Tyler Winders
Introduction: Bidirectional ventricular tachycardia (BVT) is a rare arrhythmia characterized by QRS complexes with an axis in the frontal plane alternating polarity in the precordial leads and right bundle branch block (RBBB) morphology. To the best of our knowledge, there is no previous report in dilated cardiomyopathy or in the context of a probable peripartum cardiomyopathy. Case Presentation: A 26-year-old, 9-month female patient, with no significant past medical history (the patient denies medication intake, herbs like aconite, trouble during delivery, any heart issues or family history of sudden death or cardiomyopathies) who presents to the emergency room due to 11 days of dyspnea, exacerbated by daily activities, orthopnea, and paroxysmal nocturnal dyspnea...
2020: Advanced journal of emergency medicine
D Puhr-Westerheide, T Kostbade, D-A Clevert
BACKGROUND: Motorsport karting has developed into a professional international competition. Kart racing poses a unique set of physiologic challenges for athletes who compete in this sport. Until today no major study has evaluated the physical and cardiac challenge in professional kart racing. OBJECTIVE: The aim for this study was to measure and analyze heart rate and cardiac rhythm by a mobile, smartphone based ECG (s-patch) on professional kart-race-drivers during actual karting races through annual seasons to test the hypotheses that high g-force and stress could trigger cardiac arrhythmia...
November 13, 2019: Clinical Hemorheology and Microcirculation
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