keyword
https://read.qxmd.com/read/38405437/viscoelastic-characterization-of-phantoms-for-ultrasound-elastography-created-using-low-and-high-viscosity-poly-vinyl-alcohol-with-ethylene-glycol-as-the-cryoprotectant
#1
JOURNAL ARTICLE
Sapna R Bisht, Bhanu Prasad Marri, Jayashree Karmakar, Karla P Mercado Shekhar
Ultrasound elastography enables noninvasive characterization of the tissue mechanical properties. Phantoms are widely used in ultrasound elastography for developing, testing, and validating imaging techniques. Creating phantoms with a range of viscoelastic properties relevant to human organs and pathological conditions remains an active area of research. Poly(vinyl alcohol) (PVA) cryogel phantoms offer a long shelf life, robustness, and convenient handling and storage. The goal of this study was to develop tunable phantoms using PVA with a clinically relevant range of viscoelastic properties...
February 20, 2024: ACS Omega
https://read.qxmd.com/read/37872032/superficial-bifurcated-microflow-phantom-for-high-frequency-ultrasound-applications
#2
JOURNAL ARTICLE
Anam Bhatti, Takuro Ishii, Yoshifumi Saijo
OBJECTIVE: To evaluate and optimize high-frequency ultrasound (HFUS) imaging techniques that visualize the morphology of microscale vasculatures, many studies have used flow phantoms with straight channels. However, the previous phantoms lack the complexity of microvessels to simulate a realistic vascular environment in a shallow depth. This study was aimed at devising a new protocol for fabrication of a microflow phantom with bifurcated geometry at a superficial region. METHODS: The proposed protocol involved the following features: (i) a bifurcated flow tract model 300 µm in diameter was debossed on the surface of a tissue slab made of polyvinyl alcohol cryogel, and (ii) a wall-less lumen was created via bonding tissue slabs to put a lid on the debossed flow tract...
October 21, 2023: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/37701019/extending-arterial-stiffness-assessment-along-the-circumference-using-beam-steered-arfi-and-wave-tracking-a-proof-of-principle-study-in-phantoms-and-ex-vivo
#3
JOURNAL ARTICLE
Judith T Pruijssen, Stein Fekkes, Jan Menssen, Chris L de Korte, Hendrik H G Hansen
BACKGROUND: To fully quantify arterial wall and plaque stiffness, acoustic radiation force impulse (ARFI)-induced wave-tracking along the entire vessel circumference is desired. However, attenuation and guided wave behavior in thin vessel walls limits wave-tracking to short trajectories. This study investigated the potential of beam-steered ARFI and wave-tracking to extend group velocity estimation over a larger proportion of the circumference compared to conventional 0° ARFI-induced wave-tracking...
2023: Computational and Structural Biotechnology Journal
https://read.qxmd.com/read/36826245/low-cost-pseudo-anthropomorphic-pva-c-and-cellulose-lung-phantom-for-ultrasound-guided-interventions
#4
JOURNAL ARTICLE
Natalia Arteaga-Marrero, Enrique Villa, Ana Belén Llanos González, Marta Elena Gómez Gil, Orlando Acosta Fernández, Juan Ruiz-Alzola, Javier González-Fernández
A low-cost custom-made pseudo-anthropomorphic lung phantom, offering a model for ultrasound-guided interventions, is presented. The phantom is a rectangular solidstructure fabricated with polyvinyl alcohol cryogel (PVA-C) and cellulose to mimic the healthy parenchyma. The pathologies of interest were embedded as inclusions containing gaseous, liquid, or solid materials. The ribs were 3D-printed using polyethylene terephthalate, and the pleura was made of a bidimensional reticle based on PVA-C. The healthy and pathological tissues were mimicked to display acoustic and echoic properties similar to that of soft tissues...
January 17, 2023: Gels
https://read.qxmd.com/read/36690441/overcoming-roadblocks-in-clinical-innovation-via-high-fidelity-simulation-use-of-a-phantom-simulator-to-achieve-fda-and-irb-approval-of-a-clinical-trial-of-fetal-embolization-of-vein-of-galen-malformations
#5
JOURNAL ARTICLE
Darren B Orbach, Louise E Wilkins-Haug, Carol B Benson, Shivani D Rangwala, Christopher Pak, Mona Saffarzadeh, Peter Weinstock
BACKGROUND: Vein of Galen malformation (VOGM) is a rare, life-threatening vascular malformation in neonates and is treated with embolization. However, even at the most experienced centers, patients face high mortality and morbidity. In utero treatment options have been limited by lack of animal models or simulations. OBJECTIVE: To create a novel ultrasound phantom simulator for a preclinical feasibility study of in utero fetal intervention for VOGM. METHODS: Novel phantoms were designed and built in two configurations of spherical and windsock shape from cryogel material to mimic the salient vasculature of the fetal VOGM, based on real-patient fetal MR imaging dimensions...
January 23, 2023: Journal of Neurointerventional Surgery
https://read.qxmd.com/read/36328889/characterizing-viscoelastic-polyvinyl-alcohol-phantoms-for-ultrasound-elastography
#6
JOURNAL ARTICLE
Ananya Sharma, Sai Geetha Marapureddy, Abhijit Paul, Sapna R Bisht, Manik Kakkar, Prachi Thareja, Karla P Mercado-Shekhar
Ultrasound phantoms mimic the acoustic and mechanical properties of native tissues. Polyvinyl alcohol (PVA) phantoms are used extensively as models for validating ultrasound elastography approaches. However, the viscous properties of PVA phantoms have not been investigated adequately. Glycerol is a viscous liquid that has been reported to increase the speed of sound of phantoms. This study aims to assess the acoustic and viscoelastic properties of PVA phantoms and PVA mixed with glycerol at varying concentrations...
October 31, 2022: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/36086096/nnunet-based-multi-modality-breast-mri-segmentation-and-tissue-delineating-phantom-for-robotic-tumor-surgery-planning
#7
JOURNAL ARTICLE
Motaz Alqaoud, John Plemmons, Eric Feliberti, Siqin Dong, Krishnanand Kaipa, Gabor Fichtinger, Yiming Xiao, Michel A Audette
Segmentation of the thoracic region and breast tissues is crucial for analyzing and diagnosing the presence of breast masses. This paper introduces a medical image segmentation architecture that aggregates two neural networks based on the state-of-the-art nnU-Net. Additionally, this study proposes a polyvinyl alcohol cryogel (PVA-C) breast phantom, based on its automated segmentation approach, to enable planning and navigation experiments for robotic breast surgery. The dataset consists of multimodality breast MRI of T2W and STIR images obtained from 10 patients...
July 2022: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://read.qxmd.com/read/35668220/characterization-of-blood-mimicking-fluids-for-echocardiography-imaging-of-ventricular-septal-defects
#8
JOURNAL ARTICLE
Sarah Amouri, Gerardo Tibamoso-Pedraza, Iñaki Navarro-Castellanos, Marie-Josée Raboisson, Chantale Lapierre, Joaquim Miró, Luc Duong
PURPOSE: Ventricular septal defects (VSD) are congenital heart malformations and, in severe cases, they require complex interventions under echocardiography guidance. Heart phantoms can be helpful to train and to understand the complex hemodynamics of VSD. The goal of this study was to characterize the best blood mimicking fluids in such heart phantoms for modelling the hemodynamics of VSD patients using echocardiography. METHODS: Four fluid compositions were considered...
September 2022: International Journal of Computer Assisted Radiology and Surgery
https://read.qxmd.com/read/34799525/fabrication-and-characterization-of-tissue-mimicking-phantoms-for-ultrasound-guided-cannulation-training
#9
JOURNAL ARTICLE
Rezan Jafary, Sophie Armstrong, Timothy Byrne, Andrew Stephens, Vincent Pellegrino, Shaun D Gregory
Tissue-mimicking materials (TMMs) have been investigated and used for decades as imaging phantoms in various medical applications. They are designed and fabricated to replicate certain biological tissue characteristics, a process often dictated by the target application. Moreover, TMMs have been utilized in some medical procedural training requiring the use of imaging modalities. One potential application for TMMs is ultrasound-guided cannulation training. Cannulation is a procedure that requires a level of dexterity to gain vascular access using ultrasound guidance while avoiding complications like vessel laceration and bleeding...
November 17, 2021: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/34144833/a-novel-elastography-phantom-prototype-for-assessment-of-ultrasound-elastography-imaging-performance
#10
JOURNAL ARTICLE
Fahad F Al-Mutairi, Emma Ml Chung, Carmel M Moran, Kumar V Ramnarine
The aims of this study were firstly to manufacture and evaluate a novel elastography test phantom and secondly to assess the performance of an elastography system using this phantom. A novel Leicester-St. Thomas' Elastography Pipe (L-STEP) test phantom consisting of five soft polyvinyl acrylic-cryogel pipes of varying diameters (2-12 mm), embedded at 45° within an agar-based tissue-mimicking material was developed. A shear-wave elastography (SWE) scanner was used by two blinded operators to image and assess longitudinal sections of the pipes...
September 2021: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/34021458/design-of-heart-phantoms-for-ultrasound-imaging-of-ventricular-septal-defects
#11
JOURNAL ARTICLE
Gerardo Tibamoso-Pedraza, Iñaki Navarro, Patrice Dion, Marie-Josée Raboisson, Chantale Lapierre, Joaquim Miró, Sylvie Ratté, Luc Duong
PURPOSE: Ventricular septal defects (VSDs) are common congenital heart malformations. Echocardiography used during VSD hybrid cardiac procedures requires extensive training for image acquisition and interpretation. Cardiac surgery simulators with heart phantoms have shown usefulness for such training, but they are limited in visualization and characterization of complex VSD. This study explores a new method to build patient-specific heart phantoms with VSD, with proper tissue echogenicity for ultrasound imaging...
May 21, 2021: International Journal of Computer Assisted Radiology and Surgery
https://read.qxmd.com/read/33586671/helical-toroid-phantom-for-3d-flow-imaging-investigations
#12
JOURNAL ARTICLE
Adrian J Y Chee, Takuro Ishii, Billy Y S Yiu, Alfred C H Yu
The medical physics community has hitherto lacked an effective calibration phantom to holistically evaluate the performance of three-dimensional (3D) flow imaging techniques. Here, we present the design of a new omnidirectional, three-component (3-C) flow phantom whose lumen is consisted of a helical toroid structure (4 mm lumen diameter; helically winded for 5 revolutions over a torus with 10 mm radius; 5 mm helix radius). This phantom's intraluminal flow trajectory embraces all combinations of x, y, and z directional components, as confirmed using computational fluid dynamics (CFD) simulations...
February 13, 2021: Physics in Medicine and Biology
https://read.qxmd.com/read/33429378/helical-toroid-phantom-for-3-d-flow-imaging-investigations
#13
JOURNAL ARTICLE
Adrian Chee, Takuro Ishii, Billy Y S Yiu, Alfred Yu
The medical physics community has hitherto lacked an effective calibration phantom to holistically evaluate the performance of three-dimensional (3-D) flow imaging techniques. Here, we present the design of a new omnidirectional, three-component (3-C) flow phantom whose lumen is consisted of a helical toroid structure (4 mm lumen diameter; helically winded for 5 revolutions over a torus with 10 mm radius; 5 mm helix radius). This phantom's intraluminal flow trajectory embraces all combinations of x, y, and z directional components, as confirmed using computational fluid dynamics (CFD) simulations...
January 11, 2021: Physics in Medicine and Biology
https://read.qxmd.com/read/33230246/bimodal-microwave-and-ultrasound-phantoms-for-non-invasive-clinical-imaging
#14
JOURNAL ARTICLE
Enrique Villa, Natalia Arteaga-Marrero, Javier González-Fernández, Juan Ruiz-Alzola
A precise and thorough methodology is presented for the design and fabrication of bimodal phantoms to be used in medical microwave and ultrasound applications. Dielectric and acoustic properties of human soft tissues were simultaneously mimicked. The phantoms were fabricated using polyvinyl alcohol cryogel (PVA-C) as gelling agent at a 10% concentration. Sucrose was employed to control the dielectric properties in the microwave spectrum, whereas cellulose was used as acoustic scatterer for ultrasound. For the dielectric properties at microwaves, a mathematical model was extracted to calculate the complex permittivity of the desired mimicked tissues in the frequency range from 500 MHz to 20 GHz...
November 23, 2020: Scientific Reports
https://read.qxmd.com/read/32873445/a-polyvinyl-alcohol-based-thermochromic-material-for-ultrasound-therapy-phantoms
#15
JOURNAL ARTICLE
Simone Ambrogio, Raphaela de Melo Baêsso, Alberto Gomis, Ian Rivens, Gail Ter Haar, Bajram Zeqiri, Kumar V Ramnarine, Fiammetta Fedele, Piero Miloro
Temperature estimation is a fundamental step in assessment of the efficacy of thermal therapy. A thermochromic material sensitive within the temperature range 52.5°C-75°C has been developed. The material is based on polyvinyl alcohol cryogel with the addition of a commercial thermochromic ink. It is simple to manufacture, low cost, non-toxic and versatile. The thermal response of the material was evaluated using multiple methods, including immersion in a temperature-controlled water bath, a temperature-controlled heated needle and high-intensity focused ultrasound (HIFU) sonication...
November 2020: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/32524216/a-simple-realistic-walled-phantom-for-intravascular-and-intracardiac-applications
#16
JOURNAL ARTICLE
Hareem Nisar, John Moore, Roberta Piazza, Efthymios Maneas, Elvis C S Chen, Terry M Peters
PURPOSE: This work aims to develop a simple, anatomically and haptically realistic vascular phantom, compatible with intravascular and intracardiac ultrasound. The low-cost, dual-layered phantom bridges the gap between traditional wall-only and wall-less phantoms by showing both the vessel wall and surrounding tissue in ultrasound imaging. This phantom can better assist clinical tool training, testing of intravascular devices, blood flow studies, and validation of algorithms for intravascular and intracardiac surgical systems...
September 2020: International Journal of Computer Assisted Radiology and Surgery
https://read.qxmd.com/read/31811996/polyvinyl-alcohol-cryogel-based-vessel-mimicking-material-for-modelling-the-progression-of-atherosclerosis
#17
JOURNAL ARTICLE
Andrew J Malone, Sean Cournane, Izabela G Naydenova, Andrew J Fagan, Jacinta E Browne
PURPOSE: The stiffness of Polyvinyl-alcohol cryogel can be adjusted through application of consecutive freeze-thaw cycles. This material has potential applications in the production of tissue mimicking phantoms in diagnostic ultrasound. The aim of this study was to use PVA-c to produce a range of geometrically and acoustically identical vessel phantoms modelling stages of atherosclerosis which could be verified through mechanical testing, thus allowing for more precision in quantitative in-vitro flow analysis of atherosclerosis...
December 4, 2019: Physica Medica: PM
https://read.qxmd.com/read/31128769/development-and-characterization-of-medical-phantoms-for-ultrasound-imaging-based-on-customizable-and-mouldable-polyvinyl-alcohol-cryogel-based-materials-and-3-d-printing-application-to-high-frequency-cranial-ultrasonography-in-infants
#18
JOURNAL ARTICLE
Luis Elvira, Carmen Durán, Ricardo T Higuti, Marcelo M Tiago, Alberto Ibáñez, Montserrat Parrilla, Eva Valverde, Javier Jiménez, Quique Bassat
This work presents an affordable and easily customizable methodology for phantom manufacturing, which can be used to mimic different anatomic organs and structures. This methodology is based on the use of polyvinyl alcohol-based cryogels as a physical substitute for biologic soft tissues and of 3-D printed polymers for hard tissues, moulding and supporting elements. Thin and durable soft-tissue mimicking layers and multilayer arrangements can be obtained using these materials. Special attention was paid to the acoustic properties (sound speed, attenuation coefficient and mechanical impedance) of the materials developed to simulate soft tissues...
May 22, 2019: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/30295670/manufacturing-abdominal-aorta-hydrogel-tissue-mimicking-phantoms-for-ultrasound-elastography-validation
#19
JOURNAL ARTICLE
Doran S Mix, Michael C Stoner, Steven W Day, Michael S Richards
Ultrasound (US) elastography, or elasticity imaging, is an adjunct imaging technique that utilizes sequential US images of soft tissues to measure the tissue motion and infer or quantify the underlying biomechanical characteristics. For abdominal aortic aneurysms (AAA), biomechanical properties such as changes in the tissue's elastic modulus and estimates of the tissue stress may be essential for assessing the need for the surgical intervention. Abdominal aortic aneurysms US elastography could be a useful tool to monitor AAA progression and identify changes in biomechanical properties characteristic of high-risk patients...
September 19, 2018: Journal of Visualized Experiments: JoVE
https://read.qxmd.com/read/29685590/visualizing-angle-independent-principal-strains-in-the-longitudinal-view-of-the-carotid-artery-phantom-and-in-vivo-evaluation
#20
JOURNAL ARTICLE
Rohit Nayak, Giovanni Schifitto, Marvin M Doyley
Non-invasive vascular elastography can evaluate the stiffness of the carotid artery by visualizing the vascular strain distribution. Axial strain estimates of the longitudinal cross section of the carotid artery are sensitive to the angle between the artery and the transducer. Anatomical variations in branching and arching of the carotid artery can affect the assessment of arterial stiffness. In this study, we hypothesized that principal strain elastograms computed using compounded plane wave imaging can reliably visualize the strain distribution in the carotid artery, independent of the transducer angle...
July 2018: Ultrasound in Medicine & Biology
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