Stergios K Chaloulis, Georgios Mousteris, Konstantinos T Tsaousis
Simultaneously occurring bilateral herpetic keratitis is a rare clinical manifestation of ocular herpes. Immunocompromised patients are more susceptible to develop bilateral disease. The purpose of this study is to review recent literature on the topic and to highlight latest updates, regarding risk factors and possible correlations to the disease, as well as new therapeutic options.
June 7, 2022: Tropical Medicine and Infectious Disease
Patricia Fortin, Tyler Wickas, Henry D Perry, Peter Wawrzusin, Marcelle Morcos
Purpose: To report a novel case of unilateral peripheral facial nerve palsy manifesting as a complication of Herpes simplex keratitis. Observations: A 51-year-old immunocompetent male presented with severe eye pain for 3 weeks. He was found to have Herpes simplex keratitis in the left eye and started on valacyclovir 3g per day for 10 days. At three weeks his pain and blurred vision resolved. He returned 2.5 months later with worsening of vision and five days of unilateral facial numbness and weakness...
September 2022: American Journal of Ophthalmology Case Reports
Kook Young Kim
No abstract text is available yet for this article.
April 2022: Korean Journal of Ophthalmology: KJO
Pathum Sookaromdee, Viroj Wiwanitkit
No abstract text is available yet for this article.
April 2022: Korean Journal of Ophthalmology: KJO
Amrita Mohanty, Himansu Sekhar Behera, Manas Ranjan Barik, Amanjot Kaur, Savitri Sharma, Sujata Das, Merle Fernandes, Sailendra Panda, Srikant K Sahu
BACKGROUND AND OBJECTIVE: To describe the clinical features, diagnosis and management of immune stromal keratitis/interstitial keratitis (IK) associated with microsporidial epithelial keratitis. METHODS: Between October 2020 and January 2021, medical records of IK patients microbiologically proven as microsporidia from samples collected from corneal epithelium on smear examination, and/ or molecular analysis were reviewed. Demography, clinical profile and treatment were analysed...
December 22, 2021: British Journal of Ophthalmology
Mi Yeon Song, Kyung Min Koh, Kyu Yeon Hwang, Young A Kwon, Kook Young Kim
No abstract text is available yet for this article.
February 2022: Korean Journal of Ophthalmology: KJO
Alice Matoba, John Goosey, Patricia Chévez-Barrios
PURPOSE: Microsporidial stromal keratitis is a rare form of infectious keratitis, with only 7 cases reported in the United States to date. This study was performed to evaluate risk factors, clinical features, and response to therapy. METHODS: A retrospective review of the medical records of all patients diagnosed with microsporidial stromal keratitis seen in the practices of the authors between 1999 and 2020 was performed. Diagnosis was determined by cytology or histopathology in corneal specimens...
December 1, 2021: Cornea
Rachel Louise Niederer, Jay J Meyer, Kevin Liu, Helen V Danesh-Meyer
PURPOSE: To determine the rate of moderate and severe vision loss following herpes zoster ophthalmicus (HZO) and to identify associated factors. DESIGN: Retrospective cohort study. METHODS: All subjects with acute HZO seen at a single center from 2006 to 2016 were included in the study. The primary outcome measure was the proportion of individuals with moderate and/or severe loss of vision following an acute episode of HZO. Secondary outcome measures included causes and factors associated with permanent loss of vision owing to HZO...
June 2021: American Journal of Ophthalmology
Anirban Dutta, Sujata Das, Smruti Rekha Priyadarshini
No abstract text is available yet for this article.
September 7, 2020: BMJ Case Reports
Wendy Ming, Nikhil Dewan, Sonia N Yeung, Alfonso Iovieno
BACKGROUND/OBJECTIVES: The aim of this study was to identify risk factors, prognosis, and management in patients with concomitant herpetic keratitis and acute retinal necrosis (ARN). SUBJECTS/METHODS: In this retrospective observational series, ARN patients in the Greater Vancouver area from 2004 to 2018 were identified through key words, billing codes, and dispensing data from medical records of affiliate researchers and the pharmacy at Vancouver General Hospital...
December 2020: Eye
Majid Moshirfar, Michael S Murri, Tirth J Shah, David F Skanchy, James Q Tuckfield, Yasmyne C Ronquillo, Orry C Birdsong, Daniel Hofstedt, Phillip C Hoopes
The corneal endothelium plays an integral role in regulating corneal hydration and clarity. Endotheliitis, defined as inflammation of the corneal endothelium, may disrupt endothelial function and cause subsequent visual changes. Corneal endotheliitis is characterized by corneal edema, the presence of keratic precipitates, anterior chamber inflammation, and occasionally limbal injection, neovascularization, and co-existing or superimposed uveitis. The disorder is classified into four subgroups: linear, sectoral, disciform, and diffuse...
June 2019: Ophthalmology and Therapy
Rana Altan-Yaycioglu, Serkan Poyraz
Adenoviral conjunctivitis may lead to subepithelial corneal infiltrates as a late complication. Herein, we aim to present a 19-year-old healthy female, who developed bilateral disciform keratitis three weeks after suffering adenoviral conjunctivitis. She presented with widespread subepithelial corneal infiltrates in addition to central corneal edema with white distinct border resembling immune stromal ring, as well as Descemet's folds and keratic precipitates in the central area. Following topical corticosteroid and ganciclovir for 10 days, her condition improved...
January 2018: Indian Journal of Ophthalmology
Palanisamy S Suresh
Reiter's syndrome is commonly associated with conjunctivitis and rarely with uveitis. Bilateral disciform keratitis at presentation is a very rare manifestation in Reiter's syndrome. A 13-year-old boy developed bilateral disciform keratitis with oligoarthritis following an episode of conjunctivitis. In addition he had suspected bacterial keratitis with hypopyon in the left eye as a possible secondary infection of an epithelial defect that is a feature of Reiter's keratitis. Empirical treatment with intensive topical antibiotics as a therapeutic trial completely resolved the hypopyon and the disciform keratitis settled with topical steroid treatment...
September 2016: Indian Journal of Ophthalmology
Wenjia Xie, Yesheng Xu, Yu-Feng Yao
PURPOSE: To describe a case of Descemet's membrane detachment and schisis (Descemet's membrane separated into multiple layers) with confirmation by high-definition anterior segment optical coherence tomography (AS-OCT) after phacoemulsification and intraocular lens implantation. CASE REPORT: A 72-year-old woman presented with persistent corneal edema after phacoemulsification. She was diagnosed with herpes simplex keratitis and had been unsuccessfully treated for 60 days in her local hospital...
December 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
Jun Shoji, Tohru Sakimoto, Noriko Inada, Yuko Kamei, Masao Matsubara, Etsuko Takamura, Mitsuru Sawa
PURPOSE: We performed simultaneous measurement of herpes simplex virus (HSV) DNA by real-time polymerase chain reaction (real-time PCR) and of HSV-specific secretory IgA antibody (HSV-sIgA) by enzyme-linked immunosorbent assay (ELISA) in tears obtained using Schirmer strips in order to investigate its diagnostic efficacy for herpes simplex keratitis (HSK). METHODS: A total of 59 affected eyes from 59 patients with clinically suspected HSK (HSK group) and 23 eyes from 23 healthy volunteers (control group) were enrolled in this study...
July 2016: Japanese Journal of Ophthalmology
Nisha Chadha, David A Belyea, Sanjeev Grewal
This is a case report describing two cases of disciform corneal edema following uncomplicated selective laser trabeculoplasty (SLT) thought to be secondary to herpes simplex virus (HSV) given the presence of a dendrite, decreased corneal sensation, corneal thinning, and response to therapy with oral and topical antivirals. Corneal edema after SLT treatment has been reported before, but the etiology has been unclear. Our cases highlight HSV as a likely etiology, which may help with prevention and better management of such cases in the future...
2016: Case Reports in Ophthalmological Medicine
B Seitz, A Heiligenhaus
In Europe, herpes simplex virus type I (HSV) is a common cause of keratitis. The disease may be well treated if the ophthalmologtist is aware of the various types of clinical expressions of this typical unilateral chameleon, and treatment is adjusted accordingly. Types of expression include: (i) epithelial keratitis (dendritica/geographica), (ii) stromal keratitis (necrotising vs. non-necrotising = "interstitial keratitis"), (iii) endotheliitis (= "disciform keratitis"), (iv) so-called "metaherpetic keratitis" (= neurotrophic keratopathy), (v) (vascularised) corneal scars...
June 2015: Klinische Monatsblätter Für Augenheilkunde
E Akhmedova, S Goebels, U Löw, F Bauer, N Szentmáry, B Seitz
No abstract text is available yet for this article.
June 2015: Klinische Monatsblätter Für Augenheilkunde
M Fiorentzis, N Szentmáry, B Seitz
BACKGROUND: Bilateral keratitis is rare and can have various causes. For a good outcome after treatment, the correct diagnosis is decisive. CASE REPORT: A 15-year-old boy presented to our clinic with recurrent keratoconjunctivitis and progressive loss of vision in both eyes since 6 years. The best corrected visual acuity was 0.1 in the right eye and 1/12 in the left eye. Slit-lamp examination verified keratitis disciformis with strongly vascularized corneal stromal scars without conjunctival follicles on both sides...
February 2015: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Aditya Kapoor, Rajat Jain, Srikant Sahu, Virender Sangwan
A 44-year-old man presented with severe pain, redness, watering and photophobia for 10 days in the right eye without any history of trauma. Diagnosis of herpes simplex disciform keratitis was made and he was prescribed topical steroids. The patient showed clinical worsening and presented with ring infiltrate, diffuse stromal oedema and radial keratoneuritis, a finding pathognomic of acanthamoeba keratitis. With two inconclusive corneal scrapings and the patient showing clinical worsening, an urgent therapeutic penetrating keratoplasty was carried out...
March 7, 2014: BMJ Case Reports
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