Albert M Isaacs, Joshua S Shimony, Diego M Morales, Leandro Castaneyra-Ruiz, Alexis Hartman, Madison Cook, Christopher D Smyser, Jennifer Strahle, Matthew D Smyth, Yan Yan, James P McAllister, Robert C McKinstry, David D Limbrick
OBJECTIVE: Traditionally, diffusion MRI (dMRI) has been performed in parallel with high-resolution conventional MRI, which requires long scan times and may require sedation or general anesthesia in infants and young children. Conversely, fast brain MRI permits image acquisition without the need for sedation, although its short pulse sequences, susceptibility to motion artifact, and contrast resolution have limited its use to assessing ventricular size or major structural variations. Here, the authors demonstrate the feasibility of leveraging a 3-direction fast brain MRI protocol to obtain reliable dMRI measures...
July 19, 2019: Journal of Neurosurgery. Pediatrics