Maria Coanda, Carmen Limban, Constantin Draghici, Anne-Marie Ciobanu, Georgiana Alexandra Grigore, Marcela Popa, Miruna Stan, Cristina Larion, Speranta Avram, Catalina Mares, Mariana-Catalina Ciornei, Aura Dabu, Ariana Hudita, Bianca Galateanu, Lucia Pintilie, Diana Camelia Nuta
Growing resistance to antimicrobials, combined with pathogens that form biofilms, presents significant challenges in healthcare. Modifying current antimicrobial agents is an economical approach to developing novel molecules that could exhibit biological activity. Thus, five sulfanilamide Schiff bases were synthesized under microwave irradiation and characterized spectroscopically and in silico. They were evaluated for their antimicrobial and antibiofilm activities against both Gram-positive and Gram-negative bacterial strains...
March 22, 2024: Pharmaceuticals