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JOURNAL ARTICLE
Jingyu Zhou, Zhiwen Ye, Peng Wei, Feng Yi, Min Ouyang, Shilang Xiong, Yayun Liu, Jintang Li, Min Liu, Hanrui Xi, Qianyi Peng, Long Xiong
PURPOSE: Basal metabolic rate may play a key role in the pathogenesis and progression of osteoporosis. We performed Mendelian random analysis to evaluate the causal relationship between basal metabolic rate and osteoporosis. METHODS: Instrumental variables for the basal metabolic rate were selected. We used the inverse variance weighting approach as the main Mendelian random analysis method to estimate causal effects based on the summary-level data for osteoporosis from genome-wide association studies...
2023: Frontiers in Public Health
#22
JOURNAL ARTICLE
Dong Zhang, Biao Shen, Ming Zhang, Yuchi Zhong, Ting Lü, Jingang Huang, Hongting Zhao, Li Lu
The treatment and surfactant recovery of soil washing/flushing effluent containing high levels of surfactants and organic pollutants are critical for the surfactant-assisted remediation of soils and waste management due to their complexity and high-potential risks. Combination of waste activated sludge material (WASM) and a kinetic-based two-stage system design was introduced in this study as a novel strategy for the separation of phenanthrene and pyrene from Tween 80 solutions. The results showed that WASM can effectively sorb phenanthrene and pyrene with high affinities (Kd ) of 2325...
February 16, 2023: Environmental Science and Pollution Research International
#23
JOURNAL ARTICLE
Yaqing Wei, Runzhe Yao, Xuhao Liu, Wen Chen, Jiayao Qian, Yiyi Yin, De Li, Yong Chen
The high-entropy materials (HEM) have attracted increasing attention in catalysis and energy storage due to their large configurational entropy and multiunique properties. However, it is failed in alloying-type anode due to their Li-inactive transition-metal compositions. Herein, inspired by high-entropy concept, the Li-active elements instead of transition-metal ones are introduced for metal-phosphorus synthesis. Interestingly, a new Znx Gey Cuz Siw P2 solid solution is successfully synthesized as proof of concept, which is first verified to cubic system in F-43m...
February 15, 2023: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
#24
JOURNAL ARTICLE
Wei Zhang, Juanrui Du, Kun Wang, Yige Li, Cong Chen, Long Yang, Zitong Kan, Biao Dong, Lin Wang, Lin Xu
Periodontitis, as the sixth prevalence chronic inflammation worldwide, has inconspicuous and often-overlooked symptoms at early stage, eventually leading to permanent damage to the teeth and supporting tissues. The timely and accurate diagnosis of periodontitis and monitoring its progress appear to be particularly important for clinical treatment. Herein, a dual-channel electrochemical immunosensor was developed for the synchronized detection of two periodontitis-related biomarkers in saliva: interleukin-1β (IL-1β) and matrix metalloproteinase-8 (MMP-8)...
March 22, 2023: Analytica Chimica Acta
#25
JOURNAL ARTICLE
Orthodoxia Mastrogianni, Amvrosios Orfanidis, Evdokia Brousa, Dimitrios-Phaedon Kevrekidis, Heleni Zagelidou, Nikolaos Raikos
PURPOSE: In the present study, a method for the detection of 25 psychoactive substances in cerumen was developed and validated. This method targets opiates, cocaine, antidepressants, benzodiazepines, antipsychotics and antiparkinsons. METHODS: Analysis was performed on a SCIEX Triple Quad 6500+ system after liquid-liquid extraction. Methanol with 1% acetic acid was chosen as the extraction solvent. After the addition of the solvent, samples were vortexed, sonicated, centrifuged and directly injected into the liquid chromatography-tandem mass spectrometry system...
January 2023: Forensic Toxicology
#26
JOURNAL ARTICLE
M Ramaraj, Ramamoorthy Sivakumar
In recent days, the quality of water in inland water bodies has been threatened by various natural and anthropogenic activities. Henceforth, the continuous monitoring of water quality is mandatory to control the pollution level in surface water bodies. In this work, remote sensing technology integrated with an Artificial Intelligence (AI) algorithm, a new technique called Spatio-Temporal Hybrid Novel Technique (STHNT), was used to predict, and monitor the chemical water quality pollution level through the Water Quality Index (WQI)...
December 27, 2022: Bulletin of Environmental Contamination and Toxicology
#27
JOURNAL ARTICLE
Ahmed Alduais, Ammar Al-Khawlani, Shrouq Almaghlouth, Hind Alfadda
Language acquisition, processing, comprehension, and production encompass a complex mechanism. Particularly, the mechanisms by which we make sense of language, including perception, conceptualization, and processing, have been controversial topics among cognitive linguists and researchers in cognitive sciences. Cognitive processes such as attention, thought, perception, and memory play a significant role in meaningful human communication. This study aimed to apply the science mapping method to detect and visualize emerging trends and patterns in literature pertaining to cognitive linguistics...
October 24, 2022: Journal of Intelligence
#28
Jiro Oba, Daisuke Usuda, Shiho Tsuge, Riki Sakurai, Kenji Kawai, Shun Matsubara, Risa Tanaka, Makoto Suzuki, Hayabusa Takano, Shintaro Shimozawa, Yuta Hotchi, Kenki Usami, Shungo Tokunaga, Ippei Osugi, Risa Katou, Sakurako Ito, Kentaro Mishima, Akihiko Kondo, Keiko Mizuno, Hiroki Takami, Takayuki Komatsu, Tomohisa Nomura, Manabu Sugita
BACKGROUND: Esophageal submucosal hematoma is a rare condition. Although the exact etiology remains uncertain, vessel fragility with external factors is believed to have led to submucosal bleeding and hematoma formation; the vessel was ruptured by a sudden increase in pressure due to nausea, and the hematoma was enlarged by antiplatelet or anticoagulant therapy. Serious conditions are rare, with a better prognosis. We present the first known case of submucosal esophageal hematoma-subsequent hemorrhagic shock due to Mallory-Weiss syndrome...
September 26, 2022: World Journal of Clinical Cases
#29
JOURNAL ARTICLE
Raeesa Tehreem, Iris Chen, Mudassar Raza Shah, Yumei Li, Muzammil Ahmad Khan, Kiran Afshan, Rui Chen, Sabika Firasat
Inherited retinal dystrophies (IRDs) are a heterogeneous group of degenerative disorders of the retina. Retinitis Pigmentosa (RP) is a common type of IRD that causes night blindness and loss of peripheral vision and may progress to blindness. Mutations in more than 300 genes have been associated with syndromic and non-syndromic IRDs. Recessive forms are more frequent in populations where endogamy is a social preference, such as Pakistan. The aim of this study was to identify molecular determinants of IRDs with the common presentation of night blindness in consanguineous Pakistani families...
September 10, 2022: Genes
#30
JOURNAL ARTICLE
Kenechi Nwosu-Obieogu, Emmanuel Olusola Oke, Simeon Bright
Engineering conservation during the drying process is paramount as it will help in the preservation and cost minimization of food products during processing to avoid spoilage and maximize their utilization in society. Unlike other yam species, three-leaved yam starch (TLYS) contains phytonutrients for the treatment of ailments such as diabetes and rheumatism. This work examined the energy and exergy of TLYS drying. The starch was extracted from the tuber and dried while the temperature, time, air velocity, and sample thickness were varied...
August 2022: Heliyon
#31
JOURNAL ARTICLE
Yi Zhang, Muhammad Haris, Lei Zhang, Chao Zhang, Ting Wei, Xiang Li, Yuhua Niu, Yongtao Li, Junkang Guo, Xiaojing Li
In this work, a novel amino-modified chitosan/tailings composite (CS-PEI-nGT) was successfully synthesized from gold tailings particle treated by ball milling (nGT), chitosan (CS) and polyethyleneimine (PEI) as raw materials, for Lead (Pb(Ⅱ)) and Cadmium (Cd(Ⅱ)) removal from aqueous solutions. The CS-PEI-nGT was characterized by using FTIR, XRD, SEM, BET, TGA and XPS techniques. The results showed that CS-PEI-nGT had maximum adsorption capacity of 192.78 mg g-1 and 99.46 mg g-1 for Pb(Ⅱ) and Cd(Ⅱ) respectively at pH 5...
August 20, 2022: Chemosphere
#32
JOURNAL ARTICLE
Sumeet Patiyal, Anjali Dhall, Gajendra P S Raghava
DNA-protein interaction is one of the most crucial interactions in the biological system, which decides the fate of many processes such as transcription, regulation and splicing of genes. In this study, we trained our models on a training dataset of 646 DNA-binding proteins having 15 636 DNA interacting and 298 503 non-interacting residues. Our trained models were evaluated on an independent dataset of 46 DNA-binding proteins having 965 DNA interacting and 9911 non-interacting residues. All proteins in the independent dataset have less than 30% of sequence similarity with proteins in the training dataset...
August 8, 2022: Briefings in Bioinformatics
#33
JOURNAL ARTICLE
Mallory J Owen, Sebastien Lefebvre, Christian Hansen, Chris M Kunard, David P Dimmock, Laurie D Smith, Gunter Scharer, Rebecca Mardach, Mary J Willis, Annette Feigenbaum, Anna-Kaisa Niemi, Yan Ding, Luca Van Der Kraan, Katarzyna Ellsworth, Lucia Guidugli, Bryan R Lajoie, Timothy K McPhail, Shyamal S Mehtalia, Kevin K Chau, Yong H Kwon, Zhanyang Zhu, Sergey Batalov, Shimul Chowdhury, Seema Rego, James Perry, Mark Speziale, Mark Nespeca, Meredith S Wright, Martin G Reese, Francisco M De La Vega, Joe Azure, Erwin Frise, Charlene Son Rigby, Sandy White, Charlotte A Hobbs, Sheldon Gilmer, Gail Knight, Albert Oriol, Jerica Lenberg, Shareef A Nahas, Kate Perofsky, Kyu Kim, Jeanne Carroll, Nicole G Coufal, Erica Sanford, Kristen Wigby, Jacqueline Weir, Vicki S Thomson, Louise Fraser, Seka S Lazare, Yoon H Shin, Haiying Grunenwald, Richard Lee, David Jones, Duke Tran, Andrew Gross, Patrick Daigle, Anne Case, Marisa Lue, James A Richardson, John Reynders, Thomas Defay, Kevin P Hall, Narayanan Veeraraghavan, Stephen F Kingsmore
While many genetic diseases have effective treatments, they frequently progress rapidly to severe morbidity or mortality if those treatments are not implemented immediately. Since front-line physicians frequently lack familiarity with these diseases, timely molecular diagnosis may not improve outcomes. Herein we describe Genome-to-Treatment, an automated, virtual system for genetic disease diagnosis and acute management guidance. Diagnosis is achieved in 13.5 h by expedited whole genome sequencing, with superior analytic performance for structural and copy number variants...
July 26, 2022: Nature Communications
#34
JOURNAL ARTICLE
Thomas M Fischer
(1) Background: In almost all studies of the shape of the human red blood cell (RBC), the suspending medium was a salt solution supplemented with albumin. However, the ratio of thickness across the dimple region to the thickness of the rim (THR) depends on the albumin concentration. Values of the THR in the literature range from 0.27 to 0.627 whereas in the present work it was 0.550 or 0.601 whether measured in plasma or serum. (2) Methods: 9911 RBCs of eight donors were suspended in autologous plasma or serum...
June 16, 2022: Cells
#35
JOURNAL ARTICLE
Shaowen Tan, Zili Xu
In this study, dictionary learning and expectation maximization reconstruction (DLEM) was combined to denoise 64-slice spiral CT images, and results of coronary angiography (CAG) were used as standard to evaluate its clinical value in diagnosing coronary artery diseases. 120 patients with coronary heart disease (CHD) confirmed by CAG examination were retrospectively selected as the research subjects. According to the random number table method, the patients were divided into two groups: the control group was diagnosed by conventional 64-slice spiral CT images, and the observation group was diagnosed by 64-slice spiral CT images based on the DLEM algorithm, with 60 cases in both groups...
2022: Computational and Mathematical Methods in Medicine
#36
JOURNAL ARTICLE
Zohreh Manoochehri, Sara Manoochehri, Farzaneh Soltani, Leili Tapak, Majid Sadeghifar
Background: Preeclampsia is a type of pregnancy hypertension disorder that has adverse effects on both the mother and the fetus. Despite recent advances in the etiology of preeclampsia, no adequate clinical screening tests have been identified to diagnose the disorder. Objective: We aimed to provide a model based on data mining approaches that can be used as a screening tool to identify patients with this syndrome and also to identify the risk factors associated with it...
November 2021: International Journal of Reproductive Biomedicine (Yazd, Iran)
#37
JOURNAL ARTICLE
Hamid Najafipour, Gholamreza Yousefzadeh, Mohammad Reza Baneshi, Milad Ahmadi Gohari, Beydolah Shahouzehi, Mitra Shadkam Farokhi, Ali Mirzazadeh
Background: Dyslipidemia (DL) is an important risk factor of coronary artery disease (CAD). We evaluated DL prevalence and its 5-year incidence rate in southeastern Iran, to assess the severity and growth rate of this CAD risk factor in the region. Materials and Methods: This study was a part of the Kerman CAD Risk Factors Study Phase 2 (2014-2018) among 9996 individuals aged 15-80 years, from whom 2820 individuals had also participated in Phase 1 (2009-2011). In mg/dl, cholesterol ≥240 and/or low-density lipoprotein cholesterol ≥160 and/or high-density lipoprotein cholesterol <40 for men and <50 for women and/or triglyceride >200 were defined as DL...
2021: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
#38
JOURNAL ARTICLE
Qin Hu, Jin Li, Jun Li
This study aimed to explore the therapeutic effects of neoadjuvant chemoradiotherapy (NCRT) on rectal cancer patients using the MRI based on low-rank matrix denoising algorithm, which was then compared with the postoperative pathological examination to evaluate its application value in tumor staging after NCRT treatment. 15 patients with rectal cancer who met the requirements of radiotherapy and chemotherapy after conventional MRI were selected as the research subjects. The conventional MRI images before and after NCRT treatment were divided in two groups...
2021: Journal of Healthcare Engineering
#39
Vladimir Herout, Kristian Brat, Svatopluk Richter, Ivan Cundrle
BACKGROUND: In this case report we describe an extremely rare case of cerebral air embolism following transbronchial lung biopsy (TBLB). Only a few cases of this rare complication were described previously. Every bronchologist should recognize this severe adverse event. Prompt recognition of this complication is mandatory in order to initiate supportive measures and consider hyperbaric oxygen therapy. CASE SUMMARY: In this case report we describe an extremely rare case of cerebral air embolism following TBLB...
November 16, 2021: World Journal of Clinical Cases
#40
JOURNAL ARTICLE
Li-Li Guo, Rui-Yuan Gao, Li-Hua Wang, Shu-Jun Lin, Bing-Hu Fang, Yong-da Zhao
Tulathromycin is a semi-synthetic macrolide antimicrobial that has an important role in veterinary medicine for respiratory disease. The objective of the study was to develop a pharmacokinetic/pharmacodynamic (PK/PD) model to examine the efficacy and determine an optimal dosage of tulathromycin intramuscular (IM) treatment against Haemophilus parasuis infection induced after intraperitoneal inoculation in neutropenic guinea pigs. The PKs of tulathromycin in serum and lung tissue after intramuscular administration at doses of 1, 10, and 20 mg/kg in H...
2021: Frontiers in Veterinary Science
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