keyword
https://read.qxmd.com/read/20930328/evaluation-of-a-rat-knee-mono-arthritis-using-micropet
#61
JOURNAL ARTICLE
Joseph Paquet, Fathia Maskali, Sylvain Poussier, Julien Scala Bertola, Astrid Pinzano, Laurent Grossin, Patrick Netter, Pierre Olivier, Pierre Gillet
AIM: Assessing the activity of synovitis, which is characterized by an increase in cell metabolism, is important for the prediction of future articular destruction in clinical and preclinical studies. To evaluate the correlation between ¹⁸F-FDG accumulation and arthritis pathology during its establishment, we used microPET to evaluted ¹⁸F-FDG accumulation in vivo during rat Mycobacterium wall-induced knee arthritis. METHODS: ¹⁸F-FDG PET images of arthritic rats were acquired on days 1, 2, 3 and 7 after arthritis induction...
2010: Bio-medical Materials and Engineering
https://read.qxmd.com/read/20815273/-clinical-curative-effect-of-shenxiong-bushen-capsule-and-its-effect-on-the-quality-of-life-of-patients-with-vascular-dementia
#62
RANDOMIZED CONTROLLED TRIAL
Ming-Dong Guo, Wen-Quan Zhou, Yun Wei
OBJECTIVE: To observe clinical curative effect of Shenxiong Bushen Capsule for the treatment of mild vascular dementia (VaD), and probe the partial mechanism. METHODS: With a block random, double-blinded and controled clinical research method adopted, seventy patients with VaD were randomly assigned to two groups in a ratio of 5:2, including 50 cases in the trial group and 20 cases in the control group. The patients in the trial group were given the Shenxiong Bushen Capsule (5 tablets, thrice a day), while those in the control group were given Piracetam (5 tablets, twice a day)...
June 2010: Chinese Journal of Integrated Traditional and Western Medicine
https://read.qxmd.com/read/19728366/pet-imaging-of-the-effects-of-age-and-cocaine-on-the-norepinephrine-transporter-in-the-human-brain-using-s-s-11-c-o-methylreboxetine-and-hrrt
#63
JOURNAL ARTICLE
Yu-Shin Ding, Tarun Singhal, Beata Planeta-Wilson, Jean-Dominique Gallezot, Nabeel Nabulsi, David Labaree, Jim Ropchan, Shannan Henry, Wendol Williams, Richard E Carson, Alexander Neumeister, Robert T Malison
OBJECTIVES: The role of the norepinephrine transporter (NET) in cocaine dependence has never been demonstrated via in vivo imaging due to the lack of suitable NET radioligands. Here we report our preliminary studies evaluting the NET in individuals with cocaine dependence (COC) in comparison to healthy controls (HC) using (S,S)-[(11)C]methylreboxetine ([(11)C]MRB), the most promising C-11 labeled positron-emission tomography (PET) radioligand for NET developed to date. METHODS: Twenty two human volunteers (10 COC and 12 HC) underwent dynamic (11)C-MRB-PET acquisition using a High Resolution Research Tomograph (HRRT)...
January 2010: Synapse
https://read.qxmd.com/read/19595186/-laparoscopic-radical-resection-for-gallbladder-carcinoma
#64
JOURNAL ARTICLE
Xiu-Jun Cai, Jin Yang, Hong Yu, Xiao Liang, Yi-Fan Wang, Hai Hu, Di-Yu Huang, Xue-Yong Zheng
OBJECTIVE: To evaluate the feasibility and efficacy of laparoscopic radical resection of gallbladder carcinoma. METHODS: The clinical feature, pathological stage, surgical procedure, postoperative recovery and follow-up results of 4 patients undergoing laparoscopic radical resection of gallbladder carcinoma were retrospectively analyzed. RESULTS: A total of 4 cases were successfully performed. No operative deaths and complications happened...
May 12, 2009: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://read.qxmd.com/read/19530913/paclitaxel-loaded-plga-nanoparticles-surface-modified-with-transferrin-and-pluronic-r-p85-an-in-vitro-cell-line-and-in-vivo-biodistribution-studies-on-rat-model
#65
COMPARATIVE STUDY
Neha Shah, Kiran Chaudhari, Prudhviraju Dantuluri, R S R Murthy, Susobhan Das
The development of multidrug resistance (due to drug efflux by P-glycoproteins) is a major drawback with the use of paclitaxel (PTX) in the treatment of cancer. The rationale behind this study is to prepare PTX nanoparticles (NPs) for the reversal of multidrug resistance based on the fact that PTX loaded into NPs is not recognized by P-glycoproteins and hence is not effluxed out of the cell. Also, the intracellular penetration of the NPs could be enhanced by anchoring transferrin (Tf) on the PTX-PLGA-NPs. PTX-loaded PLGA NPs (PTX-PLGA-NPs), Pluronic((R))P85-coated PLGA NPs (P85-PTX-PLGA-NPs), and Tf-anchored PLGA NPs (Tf-PTX-PLGA-NPs) were prepared and evaluted for cytotoxicity and intracellular uptake using C6 rat glioma cell line...
August 2009: Journal of Drug Targeting
https://read.qxmd.com/read/19376423/valganciclovir-induced-leukopenia-in-liver-transplant-recipients-influence-of-concomitant-use-of-mycophenolate-mofetil
#66
JOURNAL ARTICLE
E Molina Perez, J Fernández Castroagudín, S Seijo Ríos, J Mera Calviño, S Tomé Martínez de Rituerto, E Otero Antón, M Bustamante Montalvo, E Varo Perez
INTRODUCTION: An increased incidence and magnitude of leukopenia during concomitant treatment with valganciclovir (VGC) and mycophenolate mofetil (MMF) has been reported. OBJECTIVE: To evalute the incidence and severity of leukopenia and neutropenia among liver recipients treated with VGC and related factors. PATIENTS AND METHODS: Retrospective analysis of clinical and analytical data related to leukopenia (<3000 leukocytes/mm(3)) and neutropenia (<900 neutrophils/mm(3)) in liver transplant patients who were treated with VGC from 2003 to 2007...
April 2009: Transplantation Proceedings
https://read.qxmd.com/read/19014163/retrospective-radiographic-evaluation-of-the-anterior-loop-of-the-mental-nerve-comparison-between-panoramic-radiography-and-spiral-computerized-tomography
#67
COMPARATIVE STUDY
Yavuz Kaya, Metin Sencimen, Sermet Sahin, Kemal Murat Okcu, Necdet Dogan, Melike Bahcecitapar
PURPOSE: This study compares the prevalence and the length of mental loops, which were measured with panoramic radiographs and spiral computerized tomographs (SCT). MATERIALS AND METHODS: Seventy-three panoramic radiographs and 73 SCTs were taken for preoperative planning of implant placement in the interforaminal region of the anterior mandible. The bone quality of both mental regions in each patient was determined by 1 experienced calibrated clinician, and the cross-sectional images of the SCTs were evaluted for bone quality according to the Lekholm and Zarb classification...
September 2008: International Journal of Oral & Maxillofacial Implants
https://read.qxmd.com/read/18758403/immediate-loading-and-immediate-restoration-in-105-expanded-platform-implants-via-the-diem-system-after-a-16-month-follow-up-period
#68
JOURNAL ARTICLE
Jose Luis Calvo Guirado, Antonio José Ortiz Ruiz, Gerardo Gómez Moreno, Laura López Marí, Luis Alberto Bravo González
OBJECTIVE: The aim of this study was to report on our experience and outcomes with Certain Prevail Implants and immediate loading via the Diem System after a 16-month follow-up period. MATERIALS AND METHODS: Over a 16-month period, 105 (14 maxilla, 91 mandible) expanded-platform implants were placed in 18 patients (15 females, 3 males; 55.97 +/-7.25 SD years). Resonance frecuency analysis (RFA) was measured on the day of placement and at 3, 12 and 16 months. All prostheses were screw mounted on IOL DIEM standard abutments...
September 2008: Medicina Oral, Patología Oral y Cirugía Bucal
https://read.qxmd.com/read/18444559/-prospective-evaluation-of-the-risk-factors-etiology-and-the-antimicrobial-susceptibilities-of-the-isolates-in-nosocomial-bacteremic-patients
#69
JOURNAL ARTICLE
Fatma Oztürk, Sibel Gündeş, Cavit Işik
This study was aimed to assess the frequency, risk factors and etiology of bacteremia and antimicrobial susceptibilities of strains isolated from adult bacteremic patients hospitalized in Kocaeli University Hospital, Turkey during a 12-month period. Blood specimens obtained from a total of 2602 patients after at least 48 hours of hospitalization, were cultured in aerobic BACTEC 9120 and BACTEC 9050 (Becton-Dickinson, USA) automatized systems, and the identification and antibiotic susceptibilities of bacteria were performed by VITEK 1 (bioMerieux, France) system...
January 2008: Mikrobiyoloji Bülteni
https://read.qxmd.com/read/18409861/-evaluation-of-noise-risk-in-roadmen
#70
JOURNAL ARTICLE
C Giorgianni, K Trimboli, G Tanzariello, G Fontana, S Abbate, S Callipari, G Galtieri
The activity of roadman is not much knowed. The evalutation of the risk evidences the noise and vibrations as the principal polluter. The aim of our study is to go into the knowledge of the working risk of that job. The study was leaded on a sample of 287 roadmen. It was carried out an evalutation of noise exposure of the workers and a biologic evaluation that included: Medical check. Othorhin.laryngoiatric examination. Audiometric examination. Impedenzometric examination. The audiometric exam was conduced in a silent box and with a acoustic rest at least 16 h...
July 2007: Giornale Italiano di Medicina del Lavoro Ed Ergonomia
https://read.qxmd.com/read/18361250/-allograft-of-clavicle-for-reconstruction-of-bone-defect-after-tumor-resection
#71
JOURNAL ARTICLE
Zheng Guo, Zhen Wang, Zhe Wang, Yongquan Zhang
OBJECTIVE: To evaluate the effects of allogeneic bone graft for reconstructing bone defect of clavicle after tumor resection. METHODS: Nine patients received the surgical procedures for repairing and reconstructing bone defect after resection of clavicle tumor from January 2000 to January 2006. There were 4 males and 5 females aged 12 to 68 years. Two patients were diagnosed as having benign tumor and tumor-like lesion (stage III according to Campanacci grading), and 7 as having primary malignant tumor and metastatic cancer...
January 2008: Chinese Journal of Reparative and Reconstructive Surgery
https://read.qxmd.com/read/18300614/-acute-compartment-syndrome-in-the-thigh
#72
JOURNAL ARTICLE
Noam Bor, Nimrod Rozen
BACKGROUND: Compartment syndrome in the thigh is an uncomon but potentially devastating condition that has been associated with multiple etiologies mainly for motor vehicle trauma, closed or open femur fractures, and vascular injuries. The entity is more known to occur in the leg. AIM: This is a report on three patients with compartment syndrome of the thigh. One following a road accident with an open fracture of the femur and the other two patients as a result of gun shot injuries and open fractures of the femur...
January 2008: Harefuah
https://read.qxmd.com/read/18070367/peripheral-arterial-disease-study-perart-prevalence-and-predictive-values-of-asymptomatic-peripheral-arterial-occlusive-disease-related-to-cardiovascular-morbidity-and-mortality
#73
JOURNAL ARTICLE
María Teresa Alzamora, José Miguel Baena-Díez, Marta Sorribes, Rosa Forés, Pere Toran, Marisa Vicheto, Guillem Pera, María Dolores Reina, Carlos Albaladejo, Judith Llussà, Magda Bundó, Amparo Sancho, Antonio Heras, Joan Rubiés, Juan Francisco Arenillas
BACKGROUND: The early diagnosis of atherosclerotic disease is essential for developing preventive strategies in populations at high risk and acting when the disease is still asymptomatic. A low ankle-arm index (AAI) is a good marker of vascular events and may be diminished without presenting symptomatology (silent peripheral arterial disease). The aim of the PERART study (PERipheral ARTerial disease) is to determine the prevalence of peripheral arterial disease (both silent and symptomatic) in a general population of both sexes and determine its predictive value related to morbimortality (cohort study)...
2007: BMC Public Health
https://read.qxmd.com/read/17852289/self-reported-hearing-difficulties-communication-strategies-and-psychological-general-well-being-quality-of-life-in-patients-with-acquired-hearing-impairment
#74
JOURNAL ARTICLE
Lillemor R M Hallberg, Ulrika Hallberg, Sophia E Kramer
PURPOSE: The aims were to (i) translate the Amsterdam Inventory for Auditory Disability and Handicap (AIADH) into Swedish and evalute its usefulness, (ii) describe hearing difficulties and psychological well-being (quality of life) and (iii) explore variables related to psychological well-being in a Swedish population. METHOD: Seventy-nine consecutive patients, referred to the hearing clinic for hearing examination and audiological rehabilitation, formed the study sample...
2008: Disability and Rehabilitation
https://read.qxmd.com/read/17848817/renal-cell-cancer-presented-with-leptomeningeal-carcinomatosis-effectively-treated-with-sorafenib
#75
JOURNAL ARTICLE
Oliver Ranze, Erich Hofmann, Andrea Distelrath, Heinz-Gert Hoeffkes
BACKGROUND: Sorafenib has been approved in the U.S. and the European Union for patients with advanced renal cell cancer (RCC). There is evidence that treatment with sorafenib can achieve partial remissions in patients with brain metastases of RCC. CASE REPORT: We report of a patient with leptomeningeal carcinomatosis of RCC, who 10 days after initiation of sorafenib therapy showed a noticeable decrease in contrast enhancement of the tumor in a magnetic resonance imaging (MRI) scan of the brain...
September 2007: Onkologie
https://read.qxmd.com/read/17633312/-myocardial-infarction-and-nocturnal-hypoxaemia
#76
JOURNAL ARTICLE
Biljana Pencić, Milica Dekleva, Vera Celić, Zorica Rasić
INTRODUCTION: There is an increased risk of cardiovascular morbidity and mortality in patients with nocturnal intermittent hypoxaemia. OBJECTIVE: The aim of this study was to evalute the influence of nocturnal hypoxaemia on ventricular arrhythmias and myocardial ischaemia in patients with myocardial infarction (MI). METHOD: We studied 77 patients (55.8 +/- 7.9 years) with MI free of complications, chronic pulmonary diseases, abnormal awake blood gases tension...
May 2007: Srpski Arhiv za Celokupno Lekarstvo
https://read.qxmd.com/read/17582974/role-of-transrectal-ultrasonography-in-evaluting-azoospermia-causes
#77
JOURNAL ARTICLE
Fahrudin Smajlovic
Infertility is a term with which we define lack of pregnancy among sexual partners within one year of regular intercourses without use of contraceptives. The term primary infertility includes lack of any previous pregnancy, while secondary infertility is a current infertility with previous successful pregnancy. Azoospermia is an inability to produce spermatozoids in testicles or represents normal production of the spermatozoids but the obstacle is somewhere in the ejaculatory paths. Transrectal ultrasonography (TRUS) provides us with the quality and most reliable data about the urinary bladder, prostate gland...
2007: Medicinski Arhiv
https://read.qxmd.com/read/17176803/variation-in-tonsil-size-in-4-to-17-year-old-schoolchildren
#78
MULTICENTER STUDY
Ahmet Akcay, Cüneyt Orhan Kara, Erol Dagdeviren, Mehmet Zencir
OBJECTIVE: The purpose of this study was to evaluate the variation in tonsil size and prevalence of asymmetric tonsils in 4- to 17-year-old schoolchildren and the relationships between tonsillar hypertrophy and frequent tonsillitis, frequent fever, and sleep-related symptoms observed by parents. DESIGN: Cross-sectional study. SETTING: Six daycare centres, four primary schools, and four high schools. METHODS: Questionnaire and physical examination...
August 2006: Journal of Otolaryngology
https://read.qxmd.com/read/17113930/quantitative-eeg-analysis-in-post-traumatic-anosmia
#79
JOURNAL ARTICLE
E Bonanni, D Borghetti, M Fabbrini, M Maestri, F Cignoni, F Sartucci, L Murri
Many objective and quantitative methods have been developed to create a procedure or a device to prove, describe and quantify olfactory deficit and anosmia, especially after a head trauma. Electrophysiological testing throughout olfactoelectroencephalography (olfactoEEG) is based on brain activity desynchronisation, and on the subsequent disappearance of alpha activity on the posterior regions after an olfactory stimulus. Yet traditional evaluation of EEG can be difficult, because of little or hardly detectable alpha activity on the posterior regions ('alpha rare')...
December 11, 2006: Brain Research Bulletin
https://read.qxmd.com/read/17111246/evaluation-of-drotrecogin-alpha-use-in-a-belgian-university-hospital
#80
JOURNAL ARTICLE
Isabel Spriet, Wouter Meersseman, Alexander Wilmer, Geert Meyfroidt, Minne Casteels, Ludo Willems
OBJECTIVE: Sepsis remains a major cause of mortality in ICU patients, despite advances in therapy. Drotrecogin alpha (Drot AA), a recombinant human activated protein C with anti-inflammatory and anticoagulant properties, has proven to be successful in patients with at least one organ failure. Our goal was to evaluate the data in patients with sepsis and at least two organ dysfunctions in a large university hospital in Belgium. SETTING: The study was conducted at the medical and surgical intensive care units of the 1850-bed university hospital of Leuven, Belgium...
October 2006: Pharmacy World & Science: PWS
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