Chao Fan, Jia Ma, Hong-ke Zhang, Rui Gao, Jian-hui Li, Liang Yu, Zheng Wu, Yi Lv
OBJECTIVE: To explore the feasibility and efficiency of a novel magnetic compression anastomats (MCAs) in intestinal anastomosis. METHODS: A total of 36 male mongrel canines underwent intestinal anastomosis using traditional hand-sewn (n=18) or a novel MCAs (n= 18). We compared the anastomosis time, postoperative complications, bursting strength of anastomoses, gross appearance, and pathology between two groups at each timepoint of follow-up. RESULTS: The mean anastomosis time with MCAs was significantly less than that with hand-sewn (8...
September 2011: Chinese Medical Sciences Journal
Jee Hoon Jeong, Eun Tak Kim, Dae Kyung Kim
PURPOSE: This study was designed to evaluate the association of metabolic syndrome and benign prostate enlargement in young Korean males. We analyzed the clinical data associated with metabolic syndrome and prostate volume in the study population. MATERIALS AND METHODS: We retrospectively analyzed the clinical data obtained from 1,506 young men under the age of 60 who visited the health promotion center in our institution for routine checkups. The patients were interviewed with a questionnaire including the International Prostate Symptom Score (IPSS) and were evaluated by medical history, blood chemistry, digital rectal examination, and prostate volume via transrectal ultrasonography...
November 2011: Korean Journal of Urology
C Ostgathe, G Lindena, N Heussen, K Knübben, F Elsner, L Radbruch
INTRODUCTION: The German Cancer Aid funded 12 regional projects which developed different models of palliative home care. The realization of the projects were concurrently monitored and evaluated. MATERIAL AND METHODS: The funded projects were asked to document all patients who were cared for beginning in January 2009 using HOPE (Hospice and palliative survey), MIDOS (Minimal documentation system for palliative patients) and the Barthel index. Documentation was mandatory at the beginning and the end of care as well as when patients changed settings, for example when patients were transferred from a palliative care unit to a palliative home care service...
December 2011: Der Schmerz
Xiao-wei Sun, Jian-ji Zhang, Yuan-ping Ding, Fen-fen Dou, Han-bing Zhang, Ke-bo Gong, An-ting Xu
OBJECTIVE: To evalute the efficacy of high-resolution CT(HRCT) in differential diagnosis and treatment of chronic suppurative otitis media and cholesteatoma otitis media by soft-tissue shadows. METHODS: HRCT scanning was performed in 120 cases, 153 ears, with chronic otitis suppurative media and cholesteatoma otitis media, of which original data were processed with multi-planar reconstruction (MPR) and maximum intensity projection (MIP), the characteristics of the soft-tissue shadows' growth, window width or window leveling and bony destruction were respectively observed, as well as compared with the surgery findings...
May 2011: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Wenxue Chen, Yukun Zu, Qi Huang, Fener Chen, Guifang Wang, Wenxian Lan, Chunxue Bai, Shaohua Lu, Yong Yue, Feng Deng
Lung cancer causes serious health problems. Clinical diagnosis of lung cancer relies on histopathological evalution of tissue specimen. However, extensive knowledge of the metabolic biochemistry of tumors can potentially provide important information for accurate diagnosis of lung cancer. High resolution magic-angle spinning NMR spectroscopy has emerged and be widely acknowledged as an excellent tool in investigating tissue metabolism. Moreover, the combination of high resolution magic-angle spinning NMR technique and multivariate data analysis has become an important metabonomics platform for studying the intact biological tissues...
December 2011: Magnetic Resonance in Medicine
Pe dos Santos Neto, Lan dos Santos, R D Coletta, A L Laranjeira, C C de Oliveira Santos, P R Bonan, H Martelli-Júnior
OBJECTIVE: The purpose of this study was to evaluate the dentomaxillofacial imaging features of one family affected by the gingival fibromatosis (GF) and dental abnormalities (DA) syndrome. METHODS: Conventional radiographs (periapical and panoramic) and cone beam CT (CBCT) were performed in nine members of this family: four were affected by the syndrome and five were not. RESULTS: The four affected members demonstrated mild generalized GF in association with DA, including hypoplastic amelogenesis imperfecta, intrapulpal calcifications, delay on tooth eruption and pericoronal radiolucencies in unerupted teeth...
May 2011: Dento Maxillo Facial Radiology
Alessandro Fasciolo, Claudio Baldini
AIM: Subarachnoid anaesthesia has been demonstrated to be safe and effective in elderly patients. Isobaric Ropivacaine 0.5% has been recently introduced for subarachnoid anaesthesia: aim of our trial is to compare this drug with 0.5 Levobupivacaine in elderly patients scheduled for endoscopic urological surgery. METHODS: Premedication: Atropine 0.5 mg + Fenotiazine 50 mg im. Lumbar intrathecal anaesthesia, Group L (n=25) receiving Levobupivacaine 15 mg, Group R (n=25) receiving Ropivacaine 18...
January 2011: Urologia
Domenico Capone, Giovanni Tarantino, Irket Kadilli, Giuliano Polichetti, Vincenzo Basile, Stefano Federico, Massimo Sabbatini
BACKGROUND: Enteric-coated mycophenolate sodium (EC-MPS) and mycophenolate mofetil (MMF) are prodrugs of mycophenolic acid (MPA). Although many patients still receive MMF as an inosine monophosphate dehydrogenase inhibitor, EC-MPS could be considered a reliable alternative to MMF in the immunosuppressive protocols of kidney transplant recipients. MPA shows high pharmacokinetic variability and consequently a 12-h area under the curve (AUC(0-12)) should be used to guide the therapeutic dosage...
September 2011: Nephrology, Dialysis, Transplantation
Stefano Zaffagnini, Giulio Maria Marcheggiani Muccioli, Nicola Lopomo, Danilo Bruni, Giovanni Giordano, Giovanni Ravazzolo, Massimo Molinari, Maurilio Marcacci
BACKGROUND: Loss of meniscal tissue can be responsible for increased pain and decreased function. HYPOTHESIS: At a minimum 10-year follow-up, patients receiving a medial collagen meniscus implant (MCMI) would show better clinical, radiological, and magnetic resonance imaging (MRI) outcomes than patients treated with partial medial meniscectomy (PMM). STUDY DESIGN: Cohort study; Level of evidence 2. METHODS: Thirty-three nonconsecutive patients (men; mean age, 40 years) with meniscal injuries were enrolled in the study to receive MCMI or to serve as a control patient treated with PMM...
May 2011: American Journal of Sports Medicine
Dagmar Hejcmanová, Markéta Machácková, Eva Rencová, Georgia Kyprianou, Hana Langrová
The authors evalute the visual functions of patients with unilateral central serous chorioretinopathy (CSC) and compare them with their non-affected eye and with a control group. Fourteen patients with CSC treated with direct laser-photocoagulation were examined preoperatively and followed-up, up to 2 years postoperatively. Baseline best corrected visual acuity (BCVA) and contrast sensitivity (CS) of both eyes of patients was significantly lower in comparison with the controls. BCVA and CS in affected eyes were significantly lower compared to the fellow eye of patients...
2010: Acta Medica (Hradec Králové)
Mukta P Bidikar, Rati B Ichaporia
Fifty Rheumatoid arthritis (RA) patients between the age group of 20 to 60 years were investigated for sympathetic autonomic functions using standard tests. All the patients liable to develop dysautonomia or having a treatment interfering with autonomic nervous system were excluded. Previous studies to evalute sympathetic nervous system involvement used only a single test like sweating response, orthostatic test. In the present study 3 tests of sympathetic nervous system evaluation have been used. The evaluation was done by cardiovascular tests like orthostatic test, sustained hand grip and cold pressor test...
January 2010: Indian Journal of Physiology and Pharmacology
Siddiqua Aamir, Aisha
The need to recognize and manage psychiatric co-morbidity in tuberculosis (TB) patients in primary care settings in order to improve adherence to the treatment is now well documented. Pulmonary TB patients at the District TB Control Office and TB Centre in Haripur from December 2007 to March 2008 were evalute in order to assess the frequency of anxiety and depression and continuation of treatment. Forty seven out of 65 (72%) TB patients had severe/moderate level of anxiety and depression according to Hospital Anxiety and Depression Scale (HADS)...
October 2010: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Joseph Paquet, Fathia Maskali, Sylvain Poussier, Julien Scala Bertola, Astrid Pinzano, Laurent Grossin, Patrick Netter, Pierre Olivier, Pierre Gillet
AIM: Assessing the activity of synovitis, which is characterized by an increase in cell metabolism, is important for the prediction of future articular destruction in clinical and preclinical studies. To evaluate the correlation between ¹⁸F-FDG accumulation and arthritis pathology during its establishment, we used microPET to evaluted ¹⁸F-FDG accumulation in vivo during rat Mycobacterium wall-induced knee arthritis. METHODS: ¹⁸F-FDG PET images of arthritic rats were acquired on days 1, 2, 3 and 7 after arthritis induction...
2010: Bio-medical Materials and Engineering
Ming-Dong Guo, Wen-Quan Zhou, Yun Wei
OBJECTIVE: To observe clinical curative effect of Shenxiong Bushen Capsule for the treatment of mild vascular dementia (VaD), and probe the partial mechanism. METHODS: With a block random, double-blinded and controled clinical research method adopted, seventy patients with VaD were randomly assigned to two groups in a ratio of 5:2, including 50 cases in the trial group and 20 cases in the control group. The patients in the trial group were given the Shenxiong Bushen Capsule (5 tablets, thrice a day), while those in the control group were given Piracetam (5 tablets, twice a day)...
June 2010: Chinese Journal of Integrated Traditional and Western Medicine
Yu-Shin Ding, Tarun Singhal, Beata Planeta-Wilson, Jean-Dominique Gallezot, Nabeel Nabulsi, David Labaree, Jim Ropchan, Shannan Henry, Wendol Williams, Richard E Carson, Alexander Neumeister, Robert T Malison
OBJECTIVES: The role of the norepinephrine transporter (NET) in cocaine dependence has never been demonstrated via in vivo imaging due to the lack of suitable NET radioligands. Here we report our preliminary studies evaluting the NET in individuals with cocaine dependence (COC) in comparison to healthy controls (HC) using (S,S)-[(11)C]methylreboxetine ([(11)C]MRB), the most promising C-11 labeled positron-emission tomography (PET) radioligand for NET developed to date. METHODS: Twenty two human volunteers (10 COC and 12 HC) underwent dynamic (11)C-MRB-PET acquisition using a High Resolution Research Tomograph (HRRT)...
January 2010: Synapse
Xiu-Jun Cai, Jin Yang, Hong Yu, Xiao Liang, Yi-Fan Wang, Hai Hu, Di-Yu Huang, Xue-Yong Zheng
OBJECTIVE: To evaluate the feasibility and efficacy of laparoscopic radical resection of gallbladder carcinoma. METHODS: The clinical feature, pathological stage, surgical procedure, postoperative recovery and follow-up results of 4 patients undergoing laparoscopic radical resection of gallbladder carcinoma were retrospectively analyzed. RESULTS: A total of 4 cases were successfully performed. No operative deaths and complications happened...
May 12, 2009: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Neha Shah, Kiran Chaudhari, Prudhviraju Dantuluri, R S R Murthy, Susobhan Das
The development of multidrug resistance (due to drug efflux by P-glycoproteins) is a major drawback with the use of paclitaxel (PTX) in the treatment of cancer. The rationale behind this study is to prepare PTX nanoparticles (NPs) for the reversal of multidrug resistance based on the fact that PTX loaded into NPs is not recognized by P-glycoproteins and hence is not effluxed out of the cell. Also, the intracellular penetration of the NPs could be enhanced by anchoring transferrin (Tf) on the PTX-PLGA-NPs. PTX-loaded PLGA NPs (PTX-PLGA-NPs), Pluronic((R))P85-coated PLGA NPs (P85-PTX-PLGA-NPs), and Tf-anchored PLGA NPs (Tf-PTX-PLGA-NPs) were prepared and evaluted for cytotoxicity and intracellular uptake using C6 rat glioma cell line...
August 2009: Journal of Drug Targeting
E Molina Perez, J Fernández Castroagudín, S Seijo Ríos, J Mera Calviño, S Tomé Martínez de Rituerto, E Otero Antón, M Bustamante Montalvo, E Varo Perez
INTRODUCTION: An increased incidence and magnitude of leukopenia during concomitant treatment with valganciclovir (VGC) and mycophenolate mofetil (MMF) has been reported. OBJECTIVE: To evalute the incidence and severity of leukopenia and neutropenia among liver recipients treated with VGC and related factors. PATIENTS AND METHODS: Retrospective analysis of clinical and analytical data related to leukopenia (<3000 leukocytes/mm(3)) and neutropenia (<900 neutrophils/mm(3)) in liver transplant patients who were treated with VGC from 2003 to 2007...
April 2009: Transplantation Proceedings
Yavuz Kaya, Metin Sencimen, Sermet Sahin, Kemal Murat Okcu, Necdet Dogan, Melike Bahcecitapar
PURPOSE: This study compares the prevalence and the length of mental loops, which were measured with panoramic radiographs and spiral computerized tomographs (SCT). MATERIALS AND METHODS: Seventy-three panoramic radiographs and 73 SCTs were taken for preoperative planning of implant placement in the interforaminal region of the anterior mandible. The bone quality of both mental regions in each patient was determined by 1 experienced calibrated clinician, and the cross-sectional images of the SCTs were evaluted for bone quality according to the Lekholm and Zarb classification...
September 2008: International Journal of Oral & Maxillofacial Implants
Jose Luis Calvo Guirado, Antonio José Ortiz Ruiz, Gerardo Gómez Moreno, Laura López Marí, Luis Alberto Bravo González
OBJECTIVE: The aim of this study was to report on our experience and outcomes with Certain Prevail Implants and immediate loading via the Diem System after a 16-month follow-up period. MATERIALS AND METHODS: Over a 16-month period, 105 (14 maxilla, 91 mandible) expanded-platform implants were placed in 18 patients (15 females, 3 males; 55.97 +/-7.25 SD years). Resonance frecuency analysis (RFA) was measured on the day of placement and at 3, 12 and 16 months. All prostheses were screw mounted on IOL DIEM standard abutments...
September 2008: Medicina Oral, Patología Oral y Cirugía Bucal
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