keyword
https://read.qxmd.com/read/38537231/pentafecta-evaluation-in-robot-assisted-radical-prostatectomy-by-risk-group
#1
JOURNAL ARTICLE
Víctor E Corona-Montes, Juan E Sánchez-Núñez, Rocío N Gómez-López, Gerardo Fernández-Noyola
OBJECTIVE: Radical prostatectomy is a therapeutic option in organ-confined prostate cancer. As the development of robotic systems progresses, the approach with this technology has begun to impact the functional and oncological outcomes of urological patients. The objective is to report the rate of pentafecta in patients undergoing robot-assisted radical prostatectomy (RARP) stratified by risk groups. METHOD: Retrospective, observational, descriptive study from 2013 to 2020 that included 112 patients undergoing RARP...
2024: Cirugia y Cirujanos
https://read.qxmd.com/read/38536621/triglyceride-glucose-index-predicts-major-adverse-cardiovascular-events-in-patients-with-chronic-kidney-disease
#2
JOURNAL ARTICLE
Kangbo Li, Qiqi Hou, Xinyi Li, Liying Tian, Liyan Wang, Shouling Wu, Quanle Han
BACKGROUND AND PURPOSE: Triglyceride-glucose (TyG) index has been regarded as a reliable surrogate marker of insulin resistance for predicting cardiovascular outcomes. The current study aimed to explore the associations between TyG index with major adverse cardiovascular events (MACE) in patients with chronic kidney disease (CKD). METHODS/PATIENTS: 13,517 patients with chronic kidney disease (CKD) from the Kailuan study were included. Patients were divided into quartiles according to the TyG index...
March 27, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38536532/association-between-the-american-heart-association-s-new-life-s-essential-8-metrics-and-kidney-stone
#3
JOURNAL ARTICLE
Xingmo Dong, Lihua Liao, Yani Wang, Xueqin Lin, Weihua Chen, Huaijing Luo, Yi Yi, Dewen Zhong, Haifeng Wang, Zecong Ma, Yongfei Liu, Ying Liao
PURPOSE: The incidence of kidney stone disease has increased worldwide, resulting in high medical costs and social burden. Kidney stone disease shares some common features with the risk factors of cardiovascular diseases (CVDs). We investigated the association between cardiovascular health (CVH) based on the Life's Essential 8 (LE8) score developed by the American Heart Association and the incidence of kidney stone disease. METHODS: We analyzed the data of 29,469 US adults aged 20 years or above from the National Health and Nutrition Examination Survey, 2007-2018...
March 27, 2024: World Journal of Urology
https://read.qxmd.com/read/38536503/vacuum-assisted-mini-percutaneous-nephrolithotomy-is-associated-with-lower-rates-of-infectious-complications-compared-to-vacuum-cleaner-procedure-in-patients-at-high-risk-for-infections-a-single-center-experience
#4
JOURNAL ARTICLE
Andrea Marmiroli, Marco Nizzardo, Stefano Paolo Zanetti, Gianpaolo Lucignani, Matteo Turetti, Carlo Silvani, Franco Gadda, Fabrizio Longo, Elisa De Lorenzis, Giancarlo Albo, Andrea Salonia, Emanuele Montanari, Luca Boeri
PURPOSE: To evaluate the impact of vacuum-assisted mini-percutaneous nephrolithotomy (vamPCNL) vs. vacuum-cleaner mPCNL (vcmPCNL) on the rate of postoperative infectious complications in a cohort of patients with high risk factors for infections. METHODS: We retrospectively analysed data from 145 patients who underwent mPCNL between 01/2016 and 12/2022. Patient's demographics, stones characteristics and operative data were collected. vamPCNL and vcmPCNL were performed based on the surgeon's preference...
March 27, 2024: World Journal of Urology
https://read.qxmd.com/read/38535513/suprapubic-and-transurethral-bladder-access-for-voiding-cystourethrography-in-pediatric-male-patients
#5
JOURNAL ARTICLE
Wiebke Schlötelburg, Clemens Benoit, Mandy Kasper, Bernhard Petritsch, Andreas Max Weng, Thorsten Alexander Bley, Simon Veldhoen
PURPOSE: To compare suprapubic access (SPA) and transurethral catheterization (TUC) in voiding cystourethrogram (VCUG). METHODS: Retrospective single-center evaluation of 311 VCUG performed in male patients under 12 years of age. Two study groups were built based on the bladder access method. TUC was performed in 213 patients, whereas 98 received SPA. The groups were compared regarding the procedural switch rate, the complication rate, radiation parameters, the amount of contrast media applied and the examination quality...
March 13, 2024: Pediatric Reports
https://read.qxmd.com/read/38535333/matrix-and-surface-assisted-laser-desorption-ionization-mass-spectrometry-methods-for-urological-cancer-biomarker-discovery-metabolomics-and-lipidomics-approaches
#6
REVIEW
Adrian Arendowski
Urinary tract cancers, including those of the bladder, the kidneys, and the prostate, represent over 12% of all cancers, with significant global incidence and mortality rates. The continuous challenge that these cancers present necessitates the development of innovative diagnostic and prognostic methods, such as identifying specific biomarkers indicative of cancer. Biomarkers, which can be genes, proteins, metabolites, or lipids, are vital for various clinical purposes including early detection and prognosis...
March 20, 2024: Metabolites
https://read.qxmd.com/read/38534980/the-assessment-of-sf-36-survey-for-quality-of-life-measurement-after-radical-cystectomy-for-muscle-invasive-bladder-cancer-a-systematic-review
#7
REVIEW
Vlad Barbos, Bogdan Feciche, Silviu Latcu, Alexei Croitor, Vlad Dema, Razvan Bardan, Flaviu Ionut Faur, Tudor Mateescu, Dorin Novacescu, Gherle Bogdan, Alin Adrian Cumpanas
This study presents a systematic review of the literature on individuals' health-related quality of life (HRQoL) following radical cystectomy for muscle-invasive bladder cancer (MIBC), utilizing the Short Form-36 Health Survey (SF-36) as a primary assessment tool. The review was designed as an exhaustive literature search across three major databases including PubMed, Scopus, and Embase up to December 2023, using the PRISMA guidelines. The selection process refined 2281 identified articles down to 11 studies meeting our inclusion criteria...
March 16, 2024: Diseases (Basel)
https://read.qxmd.com/read/38534755/increased-apolipoprotein-a1-expression-correlates-with-tumor-associated-neutrophils-and-t-lymphocytes-in-upper-tract-urothelial-carcinoma
#8
JOURNAL ARTICLE
Chih-Chia Chang, Chia-Bin Chang, Chiung-Ju Chen, Chun-Liang Tung, Chi-Feng Hung, Wei-Hong Lai, Cheng-Huang Shen, Chang-Yu Tsai, Ya-Yan Lai, Ming-Yang Lee, Shu-Fen Wu, Pi-Che Chen
An increased neutrophil-to-lymphocyte ratio (NLR) is a poor prognostic biomarker in various types of cancer, because it reflects the inhibition of lymphocytes in the circulation and tumors. In urologic cancers, upper tract urothelial carcinoma (UTUC) is known for its aggressive features and lack of T cell infiltration; however, the association between neutrophils and suppressed T lymphocytes in UTUC is largely unknown. In this study, we examined the relationship between UTUC-derived factors and tumor-associated neutrophils or T lymphocytes...
March 7, 2024: Current Issues in Molecular Biology
https://read.qxmd.com/read/38534504/tissue-engineering-for-penile-reconstruction
#9
REVIEW
Elissa Elia, Christophe Caneparo, Catherine McMartin, Stéphane Chabaud, Stéphane Bolduc
The penis is a complex organ with a development cycle from the fetal stage to puberty. In addition, it may suffer from either congenital or acquired anomalies. Penile surgical reconstruction has been the center of interest for many researchers but is still challenging due to the complexity of its anatomy and functionality. In this review, penile anatomy, pathologies, and current treatments are described, including surgical techniques and tissue engineering approaches. The self-assembly technique currently applied is emphasized since it is considered promising for an adequate tissue-engineered penile reconstructed substitute...
February 28, 2024: Bioengineering
https://read.qxmd.com/read/38534099/psma-pet-ct-in-the-low-to-intermediate-risk-prostate-cancer-when-and-why
#10
JOURNAL ARTICLE
Luca Sofia, Matteo Bauckneht
No abstract text is available yet for this article.
March 26, 2024: Asian Journal of Andrology
https://read.qxmd.com/read/38534022/correction-to-setting-up-a-multi-disciplinary-klinefelter-syndrome-clinic-lessons-learnt-and-shared-by-s-rintoul-hoad-et%C3%A2-al
#11
(no author information available yet)
No abstract text is available yet for this article.
March 27, 2024: BJU International
https://read.qxmd.com/read/38533637/improvement-of-lower-urinary-tract-dysfunction-by-a-monoacylglycerol-lipase-inhibitor-in-mice-with-spinal-cord-injury
#12
JOURNAL ARTICLE
Kang Jun Cho, Mamoru Hashimoto, Sergei Karnup, Kanako Matsuoka, Tadanobu Kamijo, Joon Chul Kim, Jun Sung Koh, Naoki Yoshimura
AIMS: Activation of the endocannabinoid system by monoacylglycerol lipase (MAGL) blockade may affect the lower urinary tract function. We investigated the effect of an MAGL inhibitor, MJN110, on neurogenic lower urinary tract dysfunction (LUTD) in the mouse model of spinal cord injury (SCI). METHODS: Female C57BL/6 mice that underwent spinal cord transection at T8-10 level were divided into three groups consisting of (1) vehicle-treated SCI mice, (2) 5 mg/kg, or (3) 10 mg/kg of MJN110-treated SCI mice...
March 27, 2024: Neurourology and Urodynamics
https://read.qxmd.com/read/38533536/interaction-of-patient-age-and-high-grade-prostate-cancer-on-targeted-biopsies-of-mri-suspicious-lesions
#13
JOURNAL ARTICLE
Jamie S Pak, Richard Huang, William C Huang, Herbert Lepor, James S Wysock, Samir S Taneja
OBJECTIVES: To evaluate the interaction of patient age and Prostate Imaging-Reporting and Data System (PI-RADS) score in determining the grade of prostate cancer (PCa) identified on magnetic resonance imaging (MRI)-targeted biopsy in older men. PATIENTS AND METHODS: From a prospectively accrued Institutional Review Board-approved comparative study of MRI-targeted and systematic biopsy between June 2012 and December 2022, men with at least one PI-RADS ≥3 lesion on pre-biopsy MRI and no prior history of PCa were selected...
March 27, 2024: BJU International
https://read.qxmd.com/read/38533164/the-effect-of-lymphovascular-invasion-on-short-term-tumor-recurrence-and-progression-in-stage-t1-bladder-cancer
#14
JOURNAL ARTICLE
Osman Gercek, Melih Senkol, Veli Mert Yazar, Kutay Topal
Introduction Lymphovascular invasion (LVI) is the most important stage for tumor spread and metastasis. The role of LVI in transurethral resection is not yet clear. In this study, the progression and recurrences of patients who underwent transurethral resection bladder tumor (TUR-BT) and T1 high-grade tumor and concomitant LVI were detected in pathology results and were evaluated. Methods Our study included 58 patients, who underwent TUR-BT with the suspicion of bladder cancer and were pathologically diagnosed with T1 stage bladder cancer and who did not undergo radical surgery, in the Urology Clinic of Afyonkarahisar Health Sciences University, Turkey...
February 2024: Curēus
https://read.qxmd.com/read/38532550/evaluation-of-tadalafil-supplementation-on-the-neutrophil-lymphocyte-and-the-platelet-lymphocyte-ratios-in-patients-with-erectile-dysfunction-a-prospective-study
#15
JOURNAL ARTICLE
Sameh Fayek GamalEl Din, Nashaat Nabil Ismail, Hanan Hosni Moawad, Iten Mohamed Adel, Ahmad Motawi, Hisham Foaad
OBJECTIVES: We aimed to evaluate the effect of daily 5 mg tadalafil on the neutrophil/lymphocyte ratio (NLR) and the platelet/lymphocyte ratio (PLR) in patients with erectile dysfunction (ED). PATIENTS AND METHODS: 30 subjects with ED were given tadalafil as well as 30 subjects with ED who were not receiving tadalafil were recruited. 30 healthy individuals served as controls. RESULTS: Receiver operating characteristic curve (ROC) showed that the best cut off point of pre-treatment and post treatment NLR in the ED treatment group was found <1...
March 26, 2024: Urologia
https://read.qxmd.com/read/38532380/does-the-contralateral-testicular-volume-decide-the-need-for-diagnostic-laparoscopy-in-cases-of-unilateral-impalpable-undescended-testis
#16
JOURNAL ARTICLE
Ahmed Elrouby, Mahmoud Ghalab, Mostafa Kotb
BACKGROUND: This study aimed the evaluation of the value of the calculated volume of a normal testis to predict the status of its contralateral impalpable side and hence decide the importance of laparoscopic exploration. METHODS: Patients with unilateral impalpable undescended testis - as confirmed by clinical and sonographic examination- were enrolled in our prospective interventional study between November 2018 and August 2022 at Elshatby University Hospital, Faculty of Medicine, Alexandria University...
March 26, 2024: BMC Urology
https://read.qxmd.com/read/38532371/minimally-invasive-cytoreductive-radical-prostatectomy-exploring-the-safety-and-feasibility-of-a-single-port-or-multi-port-robotic-platform
#17
JOURNAL ARTICLE
Daniel J Lama, Kyle Thomas, Simone L Vernez, Oluwatimilehin Okunowo, Clayton S Lau, Bertram E Yuh
BACKGROUND: Consolidative resection or cytoreductive radical prostatectomy (CRP) may benefit men with non-organ confined prostate cancer. We report the safety, feasibility, and outcomes of robot-assisted laparoscopic CRP using a single-port (SP) or multi-port (MP) platform. METHODS: We reviewed consecutive men with clinical node positive or metastatic castrate-sensitive prostate cancer who underwent IRB-approved CRP and extended pelvic lymph node dissection using the da Vinci SP or MP Surgical Systems (Intuitive Surgical, Sunnyvale, CA) from 2015-2022...
March 26, 2024: BMC Urology
https://read.qxmd.com/read/38532370/elucidating-the-need-for-prostate-cancer-risk-calculators-in-conjunction-with-mpmri-in-initial-risk-assessment-before-prostate-biopsy-at-a-tertiary-prostate-cancer-center
#18
JOURNAL ARTICLE
Philipp Krausewitz, Thomas Büttner, Marthe von Danwitz, Richard Weiten, Alexander Cox, Niklas Klümper, Johannes Stein, Julian Luetkens, Glen Kristiansen, Manuel Ritter, Jörg Ellinger
OBJECTIVE: Utilizing personalized risk assessment for clinically significant prostate cancer (csPCa) incorporating multiparametric magnetic resonance imaging (mpMRI) reduces biopsies and overdiagnosis. We validated both multi- and univariate risk models in biopsy-naïve men, with and without the inclusion of mpMRI data for csPCa detection. METHODS: N = 565 men underwent mpMRI-targeted prostate biopsy, and the diagnostic performance of risk calculators (RCs), mpMRI alone, and clinical measures were compared using receiver operating characteristic curve (ROC) analysis and decision curve analysis (DCA)...
March 26, 2024: BMC Urology
https://read.qxmd.com/read/38532369/preliminary-findings-on-the-development-of-a-predictive-model-for-blca-based-on-disulfidptosis-associated-incrnas-signature
#19
JOURNAL ARTICLE
Chao Tang, Yanpeng Fan, Shusheng Zhu
BACKGROUND: Bladder urothelial carcinoma (BLCA) is the most common malignancy of the urinary tract, presenting with a wide range of clinical symptoms and prognosis. Disulfidptosis is a newly identified cell death method and closely associated with BLCA progression, prognosis, and treatment outcome. Currently, we need to construct a new prognostic model for disulfidptosis-related long noncoding RNAs (drlncRNAs) to improve the treatment strategy of BLCA. METHODS: The data for BLCA samples were obtained from The Cancer Genome Atlas (TCGA), and then 10 unique genes related to disulfidoptosis (DRGs) were identified from research papers...
March 26, 2024: BMC Urology
https://read.qxmd.com/read/38532363/quantitative-differentiation-of-non-invasive-bladder-urothelial-carcinoma-and-inverted-papilloma-based-on-ct-urography
#20
JOURNAL ARTICLE
Pengfei Jin, Liqin Yang, Yitao Liu, Jiehui Huang, Xu Wang
PURPOSE: To investigate the value of CT urography (CTU) indicators in the quantitative differential diagnosis of bladder urothelial carcinoma (BUC) and inverted papilloma of the bladder (IPB). MATERIAL AND METHODS: The clinical and preoperative CTU imaging data of continuous 103 patients with histologically confirmed BUC or IPB were retrospectively analyzed. The imaging data included 6 qualitative indicators and 7 quantitative measures. The recorded clinical information and imaging features were subjected to univariate and multivariate logistic regression analysis to find independent risk factors for BUC, and a combined multi-indicator prediction model was constructed, and the prediction model was visualized using nomogram...
March 26, 2024: BMC Urology
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