Blandine Gatta-Cherifi, Kamel Mohammedi, Tanguy Cariou, Christine Poitou, Philippe Touraine, Gerald Raverot, Thierry Brue, Philippe Chanson, Frédéric Illouz, Solange Grunenwald, Olivier Chabre, Emmanuel Sonnet, Thomas Cuny, Jerôme Bertherat, Sébastien Czernichow, Eric Frison, Antoine Tabarin
IMPORTANCE: A major issue in the management of craniopharyngioma-related obesity (CRO) is the ineffectiveness of the current therapeutic approaches. OBJECTIVE: To study the efficacy of glucagon-like peptide-1 analogs compared with placebo in adults with obesity CRO. DESIGN: A double-blind multicenter superiority randomized clinical in trial in two parallel arms. SETTING: Eleven French University Hospital Centers. PARTICIPANTS: Adults with CRO (body mass index > 30 kg/m²) without the sign of recurrence of craniopharyngioma in the past year...
March 30, 2024: European Journal of Endocrinology