Masahiro Tomonari, Akimitsu Kobayashi, Izumi Yamamoto, Saeko Hatanaka, Mayuko Kawabe, Takafumi Yamakawa, Haruki Katsumata, Ai Katsuma, Aki Mafune, Yasuyuki Nakada, Yusuke Koike, Jun Miki, Takahiro Kimura, Yudo Tanno, Hiroyasu Yamamoto, Takashi Yokoo
We report a case of graft intolerance syndrome in which transplant nephrectomy was performed 11 years after kidney transplantation. A 46-year-old man was admitted to our hospital in February 2018 with a mild fever, left lower abdominal pain, and gross hematuria with enlargement of the transplanted kidney. Urinary tract infection was ruled out. Because the symptoms developed after the immunosuppressants had been stopped after kidney graft loss, graft intolerance syndrome was suspected. He had lost his graft in 2016 and had stopped all immunosuppressants since January of 2017...
November 26, 2020: Nephron
Diego de Farias Silva, Pedro Henrique Simões Bezerra, Leonardo Lopes de Sousa Ribeiro, Max Denisson Maurício Viana, Alyne Almeida de Lima, Geraldo José da Silva Neto, Claudener Souza Teixeira, Sônia Salgueiro Machado, Magna Suzana Alexandre Moreira, Plinio Delatorre, Eliane Aparecida Campesatto, Bruno Anderson Matias da Rocha
ETHNOPHARMACOLOGICAL RELEVANCE: Since drugs currently used to manage pain and inflammatory conditions present several side effects, the investigation of new anti-inflammatory and antinociceptive agents from folk-medicine plants is an important approach. Costus spiralis (Costaceae) has been used in Brazilian medicinal teas to treat urinary infection, cough, inflammation, arthritis, among others. AIM OF THE STUDY: The current study focused on investigating anti-inflammatory and antinociceptive effects of fractions from C...
November 23, 2020: Journal of Ethnopharmacology
Joseph Ryan Leach, Bryan Manoukian, Lygia Stewart
We present the case of a 60-year-old man with a complex medical history, presenting to the hospital with generalized weakness and found to be markedly hyperglycemic. Early in the patient's hospital course, he developed abdominal pain and was found to have a small bowel obstruction secondary to intraluminal migrated surgical mesh entrapped in the terminal ileum. The bowel obstruction was relieved surgically with uncomplicated mesh removal and ileocecectomy. Surgical mesh migration is a relatively rare complication of hernia repair and abdominal wall reconstruction, and intraluminal mesh migration is an even more rare variant...
November 25, 2020: Clinical Journal of Gastroenterology
Christopher N Andrews, Marc Bradette
Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disorder, which impacts the quality of life, work productivity and social activities of patients. Diarrhea-predominant IBS (IBS-D) is one of several subtypes, and accounts for approximately one third of all cases. Currently available treatments are typically unable to alleviate the cardinal symptoms of IBS-D, including abdominal pain and diarrhea, and a clinical unmet need remains for an effective treatment which simultaneously relieves multiple symptoms...
December 2020: Journal of the Canadian Association of Gastroenterology
Tarkeshwar Tiwary, Shalanki Baiswar, Praveen Jinnur
A young male with long-standing type 1 diabetes mellitus, chronic kidney disease, and known ventricular hypertrophy presented with dyspnea and abdominal pain and was diagnosed with coronavirus disease 2019 (COVID-19) infection. On day nine of hospital admission, patient developed ventricular tachycardia with electrocardiogram (ECG) changes and elevation in troponin level consistent with myocarditis and development of cardiogenic shock. Bedside limited echo demonstrated signs of tamponade and patient underwent surgical pericardial window procedure...
November 22, 2020: Curēus
Sara Lourenço, Ana Marta Pereira, Marta Guimarães, Mário Nora
Gastric volvulus is a rare but potentially life-threatening condition, with difficult diagnosis. We present a case report of a demented woman aged 65 years that attended the emergency department with epigastric pain and vomiting for the past 10 days. The chest plain revealed a retrocardiac air-filled mass and the abdomino-pelvic computed tomography confirmed the diagnosis of gastric volvulus. The patient was admitted. A nasogastric tube was introduced, antibiotics and parenteric nutrition were started and the patient didn't eat anything...
October 24, 2020: Curēus
Mohamed Elnaggar, Jagmohan S Jandu, Bryce D Beutler, Sally Leong, Robert McCain
Acute mesenteric vein thrombosis represents a rare but potentially lethal thrombotic event. Its treatment involves prompt and aggressive anticoagulation therapy. In the perioperative setting, management of the underlying thrombus must be weighed carefully against the risk of bleeding. We describe a 57-year-old man who presented with abdominal pain and was found to have terminal ileitis with concomitant superior mesenteric vein thrombosis.
October 23, 2020: Curēus
Kentaro Kawamura, Shinobu Fukumura, Koki Nikaido, Nobutada Tachi, Naoki Kozuka, Tsugumi Seino, Kingya Hatakeyama, Mitsuru Mori, Yoichi M Ito, Akiyoshi Takami, Shiro Hinotsu, Atsushi Kuno, Yukihiko Kawasaki, Yoshiyuki Horio, Hiroyuki Tsutsumi
Muscular dystrophies (MDs) are inherited disorders characterized by progressive muscle weakness. Previously, we have shown that resveratrol (3,5,4'-trihydroxy-trans-stilbene), an antioxidant and an activator of the protein deacetylase SIRT1, decreases muscular and cardiac oxidative damage and improves pathophysiological conditions in animal MD models. To determine whether resveratrol provides therapeutic benefits to patients with MDs, an open-label, single-arm, phase IIa trial of resveratrol was conducted in 11 patients with Duchenne, Becker or Fukuyama MD...
November 25, 2020: Scientific Reports
Binita Bhandari, Samantha A Snyder, John D Goldman
BACKGROUND Extrapulmonary tuberculosis (TB) occurs in up to one-fifth of all cases of TB, with abdominal TB accounting for 5% of all cases. It is an uncommon diagnosis in the Western world, where it is primarily identified in immigrant and immunocompromised populations. CASE REPORT We review a case in which a 47-year-old Nepalese woman with a history of cognitive dysfunction secondary to epilepsy presented with decreased appetite and diffuse abdominal pain. She was hypoxic and febrile on initial exam, and imaging indicated lung consolidation, right-sided pleural effusion, and thickening and nodularity of the omentum with patchy wall thickening of the colon...
November 26, 2020: American Journal of Case Reports
Ying Peng, Cheng Peng
BACKGROUND: Ogilvie syndrome, also known as acute colonic pseudo-obstruction (ACPO), can occur postpartum after caesarean section (C-section), often resulting in caecal dilatation. The incidence rate is approximately 100 cases in 100,000 patients per year (Ross et al., Am Surg 82:102-11, 2016). Without proper diagnosis and treatment, it may progress to intestinal perforation or other fatal complications. CASE PRESENTATION: A 39-year-old pregnant woman underwent emergency low-segment C-section due to complications of Haemolysis, Elevated Liver enzymes and Low Platelets syndrome (HELLP) syndrome...
November 25, 2020: BMC Pregnancy and Childbirth
Sulai Liu, Zhendong Zhong, Meng Xiao, Yinghui Song, Youye Zhu, Bo Hu, Zengpeng Sun, Weimin Yi, Chuang Peng
BACKGROUND: The World Health Organization's updated classification of digestive system neuroendocrine tumors in 2010 first proposed the classification of mixed adenoneuroendocrine carcinoma (MANEC). The incidence of biliary malignant tumors with neuroendocrine tumors accounts for less than 1% of all neuroendocrine tumors. Moreover, the incidence of hilar bile duct with MANEC is very rare. CASE PRESENTATION: A 65-year-old female patient came to our hospital for repeated abdominal pain for more than 4 months and skin sclera yellow staining for 1 week...
November 25, 2020: BMC Gastroenterology
Inna Polyakova, Glen Iannucci, Roshan George, Anne Gill, Dinesh Govind Patel, Kelly Rouster-Stevens
A 14-year-old female with no significant medical history presented with hypertensive urgency, in the setting of 4 to 6 weeks of diarrhea, abdominal pain, headaches, anemia, weight loss, and high blood pressures. Her evaluation revealed signs of a systemic inflammatory process that was most suspicious for inflammatory bowel disease. However, when her hypertension was evaluated with a renal Doppler ultrasound, there were signs of narrowing, stenosis, and hypoplasia that led to a diagnostic angiogram of the abdominal aorta...
January 2020: Journal of Investigative Medicine High Impact Case Reports
Nathaly Cortez, Manuel Berzosa, Kiranmayi Muddasani, Kfir Ben-David
Sigmoid volvulus is a rare condition seen during pregnancy with high maternal and fetal morbidity and mortality. We report a case of a young 26-year-old woman, primipara, in her third trimester who presented with recurrent sigmoid volvulus at both 30 and 32 weeks of gestation. She underwent successful repetitive endoscopic decompression on both admissions with uneventful recovery. Endoscopic evaluation is safe in pregnancy and uncomplicated volvulus. It allows for diagnostic confirmation and assessment of complications; and it has successful outcomes in the presence of a multidisciplinary team...
January 2020: Journal of Investigative Medicine High Impact Case Reports
F Köckerling, W Brunner, R Fortelny, F Mayer, D Adolf, H Niebuhr, R Lorenz, W Reinpold, K Zarras, D Weyhe
INTRODUCTION: Based on meta-analyses and registry data, the European Hernia Society and the Americas Hernia Society have published guidelines for the treatment of umbilical hernias. These recommend that umbilical hernia should generally be treated by placing a non-absorbable (permanent) flat mesh into the preperitoneal space with an overlap of the hernia defect of 3 cm. Suture repair should only be considered for small hernia defects of less than 1 cm. Hence, the use of a mesh in general is subject to controversial debate particularly for small (< 2 cm) umbilical hernias...
November 25, 2020: Hernia: the Journal of Hernias and Abdominal Wall Surgery
Kyota Tatsuta, Mayu Sakata, Kosuke Sugiyama, Toshiya Akai, Katsunori Suzuki, Yuhi Suzuki, Takafumi Kawamura, Yoshifumi Morita, Hirotoshi Kikuchi, Yoshihiro Hiramatsu, Kiyotaka Kurachi, Hiroya Takeuchi
BACKGROUND: Adult intussusception is recognized as an abdominal emergency. More than 90% of adult patients with intussusception have distinct causes that are related to benign or malignant tumors. In contrast, idiopathic intussusceptions, which are observed in children, are rare conditions in adult. Especially, colo-colonic idiopathic intussusceptions are rare among them. Surgery is traditionally considered the primary treatment option. Recently, laparoscopic surgery has been reported to be safe and feasible...
November 25, 2020: Surgical Case Reports
Eoin MacCraith, Eoghan M Cunnane, Michael Joyce, James C Forde, Fergal J O'Brien, Niall F Davis
BACKGROUND: The aim of this study is to systematically compare rates of erosion and chronic pain after mesh insertion for pelvic organ prolapse (POP) and stress urinary incontinence (SUI) surgery. METHODS: A systematic electronic search was performed on studies that evaluated the incidence of erosion and chronic pain after mesh insertion for POP or SUI. The primary outcome measurement was to compare mesh erosion rates for POP and SUI surgery. Secondary outcome measurements were incidence of de novo pain and a comparison of patient demographics for both surgeries...
November 25, 2020: International Urogynecology Journal
Fernanda Prata Martins, Silvia Mansur Reimão Seleti, Mônica Lucia Contini, Gustavo Andrade DE Paulo, Angelo Paulo Ferrari
BACKGROUND: Biliary complications remain one of the most important causes of morbidity and graft loss after liver transplant (LT). Endoscopic therapy of biliary complications has proven to be effective over time, leaving surgical treatment restricted to only very few cases. However, we cannot yet predict which patients will have the greatest potential to benefit from endoscopic treatment. OBJECTIVE: On this premise we decide to conduct this study to evaluate the role and safety of single operator cholangioscopy (SOC) in the endoscopic treatment of post-LT biliary anastomotic strictures (AS)...
November 20, 2020: Arquivos de Gastroenterologia
André Thá Nassif, Thais Ayumi Nagano, Izabela Rodrigues Villela, Giulianna Ribas Simonetti, Bruno Francisco Dias, Alexandre Coutinho Teixeira de Freitas
BACKGROUND: Rives-Stoppa retromuscular technique: A) polypropylene mesh fixed on the posterior rectus sheath; B) rectus abdominal muscle; C) anterior rectus sheath being sutured. The best technique for incisional hernioplasty has not been established yet. One of the difficulties to compare these techniques is heterogeneity in the profile of the patients evaluated. AIM: To analyze the results of three techniques for incisional hernioplasty after open bariatric surgery...
2020: Brazilian Archives of Digestive Surgery: ABCD
Carmen Parisio, Elena Lucarini, Laura Micheli, Alessandra Toti, Maria Bellumori, Lorenzo Cecchi, Laura Calosi, Daniele Bani, Lorenzo Di Cesare Mannelli, Nadia Mulinacci, Carla Ghelardini
Management of abdominal pain, a common symptom of IBDs and IBS, is still a clinical problem. Extra virgin olive oil (EVOO), a main component of the Mediterranean diet, shows positive effects on chronic inflammation in IBDs. In this study, the effect of the oral administration of EVOO (3 mL) and two olive milling by-products, DPA (300 mg kg-1) and DRF (300 mg kg-1), on preventing the development of abdominal pain in a DNBS-induced colitis model in rats was evaluated. The doses were chosen with the aim of simulating a plausible daily intake in humans...
November 25, 2020: Food & Function
Nanhui Jiang, Bihai Hao, Rong Huang, Fengying Rao, Ping Wu, Zhen Li, Chunxue Song, Zhisu Liu, Tao Guo
Objective . We conducted a meta-analysis to quantitatively evaluate the effects of abdominal binder in abdominal surgeries. Methods . Through literature retrieval in globally recognized databases (MEDLINE, EMBASE, and Cochrane Central), trials investigating the application of abdominal binder in abdominal surgeries were systematically reviewed. The main outcomes, namely, 6-minute walk test (6MWT), visual analog scale (VAS) pain score, and symptom distress scale (SDS) score, were pooled to make an overall estimation...
November 25, 2020: Surgical Innovation
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