Selena Aranda, Esther Jiménez, Erick J Canales-Rodríguez, Norma Verdolini, Silvia Alonso, Esteban Sepúlveda, Antonio Julià, Sara Marsal, Julio Bobes, Pilar A Sáiz, Paz García-Portilla, Jose M Menchón, José M Crespo, Ana González-Pinto, Víctor Pérez, Celso Arango, Pilar Sierra, Julio Sanjuán, Edith Pomarol-Clotet, Eduard Vieta, Elisabet Vilella
The DDR1 locus is associated with the diagnosis of schizophrenia and with processing speed in patients with schizophrenia and first-episode psychosis. Here, we investigated whether DDR1 variants are associated with bipolar disorder (BD) features. First, we performed a case‒control association study comparing DDR1 variants between patients with BD and healthy controls. Second, we performed linear regression analyses to assess the associations of DDR1 variants with neurocognitive domains and psychosocial functioning...
February 19, 2024: Molecular Psychiatry