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Ken Kodama, Toru Momozane, Hiroshi Takehara, Masanori Kaneko, Hirotsugu Honda
An invasive pneumococcal disease involving sternoclavicular joint arthritis, lumbar spondylodiscitis, and muscular abscesses caused by penicillin-resistant Streptococcus pneumoniae has not been reported previously. We successfully treated a 57-year-old man with this condition using surgical drainage and debridement, and laminectomy/fenestration, in combination with the administration of two IV antimicrobial drugs based on blood culture results. Clinical resolution was obtained after decompression of the lumbar spine, with minimal restriction of the left lower limb...
April 2024: Curēus
#22
Ben Brahim Safouen, Jlidi Mohamed, Ben Ammar Ahmed, Bouaicha Walid, Daas Selim, Khorbi Adel
INTRODUCTION AND IMPORTANCE: Septic arthritis (SA), an infection affecting joints, is primarily attributed to bacteria, viruses, or fungi, with the hip, knee, and ankle being common sites of involvement. However, SA of the proximal tibiofibular joint is exceptionally rare. We report a highly uncommon case of lateral knee pain with fever in an 11-year-old boy caused by SA of the proximal tibiofibular joint. CASE PRESENTATION: The case involves an 11-year-old male admitted with atraumatic knee pain, fever, and limping...
April 20, 2024: International Journal of Surgery Case Reports
#23
JOURNAL ARTICLE
Chun Yuet Khoo, Cynthia Ming Li Chia
Septic arthritis of the sternoclavicular joint (SCJ) is a rare condition that comprise less than 1% of all joint infections. We report a case of severe bilateral septic arthritis of the SCJ in a patient with end-stage renal disease on peritoneal dialysis. A 44 year-old female presented with right SCJ infection one month after recovering from a tenckhoff catheter exit-site infection. She completed six weeks of antibiotics however this progressed to bilateral SCJ septic arthritis with osteomyelitis necessitating multiple surgical debridement and excision of bilateral clavicular heads...
April 27, 2024: Interdiscip Cardiovasc Thorac Surg
#24
JOURNAL ARTICLE
Romy Takken, Sander Mol, Samara Guillen, Nicole A Volkers
BACKGROUND: Septic sacroiliitis is an uncommon disease which represents approximately 1-4% of all joint infections, therefore it is difficult to make the right diagnosis and to start early treatment. CASE REPORT: A 18 year old woman was admitted to the emergency room with a fever and pain in the left gluteal region. The patient was considered healthy and had no risk factors for septic arthritis. Edema and a small abscess was found in and around the left sacroiliac joint on pelvic MRI...
April 22, 2024: Nederlands Tijdschrift Voor Geneeskunde
#25
JOURNAL ARTICLE
T Hospach, T Kallinich, L Martin, T V Kalle, F Reichert, H J Girschick, C M Hedrich
Bacterial arthritis and osteomyelitis are usually acute diseases, which in this way differ from the often insidious course of nonbacterial osteomyelitis; however, there is often an overlap both in less acute courses of bacterial illnesses and also in nonbacterial osteitis. The overlapping clinical phenomena can be explained by similar pathophysiological processes. In bacteria-related illnesses the identification of the pathogen and empirical or targeted anti-infectious treatment are prioritized, whereas no triggering agent is known for nonbacterial diseases...
April 23, 2024: Zeitschrift Für Rheumatologie
#26
JOURNAL ARTICLE
Benjamin D Pesante, Maryam Salimi, Whitney L Miller, Heather L Young, Timothy C Jenkins, Joshua A Parry
INTRODUCTION: Distinguishing between septic arthritis and crystal arthropathy flares can be challenging. The purpose of this study was to determine how the presence of synovial crystals affects the diagnostic criteria of septic arthritis. METHODS: A retrospective review identified patients undergoing joint aspirations to rule out native septic arthritis. Differences between septic arthritis presenting with and without synovial crystals were analyzed. A receiver-operating characteristic curve was plotted for laboratory markers to determine the area under the curve, or diagnostic accuracy, for septic arthritis and to evaluate thresholds that maximized sensitivity and specificity...
April 17, 2024: Journal of the American Academy of Orthopaedic Surgeons
#27
JOURNAL ARTICLE
Sarah Zambrano, Molly L Paras, Joji Suzuki, Jeffrey C Pearson, Brandon Dionne, Harry Schrager, Jason Mallada, Veronica Szpak, Katie Fairbank-Haynes, Marlene Kalter, Sara Prostko, Daniel A Solomon
BACKGROUND: Dalbavancin has been used off-label to treat invasive bacterial infections in vulnerable populations like people who use drugs (PWUD) because of its broad gram-positive coverage and unique pharmacological properties. This retrospective, multisite study examined clinical outcomes at 90 days in PWUD versus non-PWUD after secondary treatment with dalbavancin for bacteremia, endocarditis, osteomyelitis, septic arthritis, and epidural abscesses. METHODS: Patients at 3 teaching hospitals who received dalbavancin for an invasive infection between March 2016 and May 2022 were included...
April 2024: Open Forum Infectious Diseases
#28
JOURNAL ARTICLE
Jillian L Paegelow, Mike J Schoonover, Jenna M Young, Lara K Maxwell, Jared D Taylor, Lyndi L Gilliam, Todd C Holbrook
BACKGROUND: Pharmacokinetics of amikacin administered IV to neonatal foals are described, but little data are available regarding the plasma concentrations contributed by concurrent intra-articular (IA) administration. HYPOTHESIS/OBJECTIVES: Compare the pharmacokinetics of amikacin when the total dose is administered IV compared to being divided between IV and IA routes of administration in neonatal foals and predict the plasma concentrations from various combined IV and IA dosing regimens...
April 22, 2024: Journal of Veterinary Internal Medicine
#29
JOURNAL ARTICLE
Keming Sun, Chunxu Zhang, Ziwen Mao, Chen Wang, Hua Zhu, Huiqing Sun, Kang Wang, Weyland Cheng
OBJECTIVE: Signs and symptoms of osteomyelitis or septic arthritis in neonates and infants are often nonspecific and early-stage bone infections in infants may often go unnoticed. The objective of this study was to analyze the clinical characteristics of newborns and infants with osteomyelitis and septic arthritis to improve understanding of the disorder and to assist clinicians with diagnosis. METHODS: A retrospective multicenter study was conducted on neonates (0-28 days old, n = 94) and infants (1-12 months old, n = 415) with osteoarticular infections...
April 17, 2024: Jornal de Pediatria
#30
REVIEW
Pim Jetanalin, Yanint Raksadawan, Pholaphat Charles Inboriboon
Acute nontraumatic joint pain has an extensive differential. Emergency physicians must be adept at identifying limb and potentially life-threatening infection. Chief among these is septic arthritis. In addition to knowing how these joint infections typically present, clinicians need to be aware of host and pathogen factors that can lead to more insidious presentations and how these factors impact the interpretation of diagnostic tests.
May 2024: Emergency Medicine Clinics of North America
#31
JOURNAL ARTICLE
Grace E M Kennedy, Abisha Tharmaseelan, Jonathan R A Phillips, Jon T Evans, Setor K Kunutsor
AIMS: Septic arthritis (SA) of the native knee joint is associated with significant morbidity. This review compared post-operative functional outcomes (patient-reported outcome measures (PROMs) and range of movement (ROM)) following arthroscopic washout (AW) and open washout (OW) amongst adult patients with SA of the native knee. The need for further operative intervention was also considered. METHODS: Electronic databases of PubMed, MEDLINE, Embase, Cochrane, Web of Science and Scopus were searched between 16 February 2023 and 18 March 2023...
April 12, 2024: Systematic Reviews
#32
JOURNAL ARTICLE
Stéphanie Pascual, Brooklyn Noble, Nusreen Ahmad-Saeed, Catherine Aldridge, Simone Ambretti, Sharon Amit, Rachel Annett, Shaan Ashk O'Shea, Anna Maria Barbui, Gavin Barlow, Lucinda Barrett, Mario Berth, Alessandro Bondi, Nicola Boran, Sara E Boyd, Catarina Chaves, Martin Clauss, Peter Davies, Ileana T Dianzo-Delgado, Jaime Esteban, Stefan Fuchs, Lennart Friis-Hansen, Daniel Goldenberger, Andrej Golle, Juha O Groonroos, Ines Hoffmann, Tomer Hoffmann, Harriet Hughes, Marina Ivanova, Peter Jezek, Gwennan Jones, Zeynep Ceren Karahan, Cornelia Lass-Flörl, Frédéric Laurent, Laura Leach, Matilde Lee Horsbøll Pedersen, Caroline Loiez, Maureen Lynch, Robert J Maloney, Martin Marsh, Olivia Milburn, Shanine Mitchell, Luke S P Moore, Lynn Moffat, Marianna Murdjeva, Michael E Murphy, Deepa Nayar, Giacomo Nigrisoli, Fionnuala O'Sullivan, Büşra Öz, Teresa Peach, Christina Petridou, Mojgan Prinz, Mitja Rak, Niamh Reidy, Gian Maria Rossolini, Anne-Laure Roux, Patricia Ruiz-Garbajosa, Kordo Saeed, Llanos Salar-Vidal, Carlos Salas Venero, Mathyruban Selvaratnam, Eric Senneville, Peter Starzengruber, Ben Talbot, Vanessa Taylor, Rihard Trebše, Deborah Wearmouth, Birgit Willinger, Marjan Wouthuyzen-Bakker, Brianne Couturier, Florence Allantaz
Introduction : The BIOFIRE Joint Infection (JI) Panel is a diagnostic tool that uses multiplex-PCR testing to detect microorganisms in synovial fluid specimens from patients suspected of having septic arthritis (SA) on native joints or prosthetic joint infections (PJIs). Methods : A study was conducted across 34 clinical sites in 19 European and Middle Eastern countries from March 2021 to June 2022 to assess the effectiveness of the BIOFIRE JI Panel. Results : A total of 1527 samples were collected from patients suspected of SA or PJI, with an overall agreement of 88...
2024: Journal of Bone and Joint Infection
#33
JOURNAL ARTICLE
Jordi Cools, Stijn Ghijselings, Fred Ruythooren, Sander Jentjens, Nathalie Noppe, Willem-Jan Metsemakers, Georges Vles
Background : Septic arthritis (SA) of the native adult hip is a rare orthopaedic emergency requiring prompt diagnosis and treatment. As clinical presentation and laboratory findings are frequently atypical, advanced imaging is often requested. This retrospective study aimed to investigate the prevalence and pattern of extra-articular infectious manifestations and their implications for pre-operative advanced imaging in patients with proven SA of the native hip joint. Methods : Out of 41 patients treated surgically for SA of the native hip during a 16-year period at our tertiary referral hospital, 25 received advanced imaging (computed tomography (CT), magnetic resonance imaging (MRI), or fluorodeoxyglucose positron emission tomography (FDG PET-CT)) prior to initial intervention...
2024: Journal of Bone and Joint Infection
#34
REVIEW
Mahesh Prakash, Madhurima Sharma, Anindita Sinha, Shayeri Roy Choudhury, Devendra Kumar Chouhan
Arthropathies are a frequent cause of shoulder pain and comprise of a wide range of clinical entities that may pose a diagnostic challenge. Though history and clinical examination remain vital, imaging plays a pivotal role in accurate diagnosis. Magnetic resonance imaging (MRI) remains an invaluable tool for imaging evaluation of shoulder involvement by various arthropathies. With attention to characteristic imaging features, radiologist may be able to differentiate between various disease processes affecting the shoulder joint...
March 2024: Journal of Clinical Orthopaedics and Trauma
#35
Thais H de Palma, Chris Powers, Morgan J McPartland, Jessica Mark Welch, Matthew Ramsey
Haemophilus parainfluenzae ( Hp ) is a Gram-negative, pleomorphic rod, highly prevalent and abundant as a commensal in the human oral cavity, and an infrequent extraoral opportunistic pathogen. Hp occupies multiple niches in the oral cavity, including the tongue dorsum, keratinized gingiva, and the supragingival plaque biofilm. As a member of the HACEK group, Hp is also known to cause infective endocarditis. Additionally, case reports have identified Hp as the causative agent of meningitis, septic arthritis, chronic osteomyelitis, septicemia, and a variety of other infectious diseases...
March 31, 2024: bioRxiv
#36
Mohammad Danish Mangi, WanYin Lim
Vesico-acetabular fistula formation is a rare condition typically associated with total hip arthroplasty. Clinical features can include pain of the hip and flank, haematuria, and dysuria. We report the case of a 67-year-old female with a past medical history of bilateral pelvic fractures and calcium hydroxyapatite deposition disease of the hip joint, who developed vesico-acetabular fistula in the absence of surgery. This was then complicated by septic arthritis. We highlight the ultrasound, computed tomography (CT) and magnetic resonance imaging (MRI) findings of the case and review the previous case reports describing the vesico-acetabular fistula...
June 2024: Radiology Case Reports
#37
JOURNAL ARTICLE
M Shihabul Hassan, J Stevenson, G Gandikota, A Veeratterapillay, K D P Bhamidipaty, R Botchu
This article presents a comprehensive overview of the diagnostic utility of existing imaging techniques including radiography, computed tomography, ultrasonography, magnetic resonance imaging (MRI), and radionuclide imaging in the context of the most common orthopaedic or musculoskeletal infections. It also includes illustrative images showcasing significant findings in various musculoskeletal infections including osteomyelitis, cellulitis, septic arthritis, necrotising infections and peri-prosthetic joint infections and their associated complications...
April 2024: Journal of Clinical Orthopaedics and Trauma
#38
Yoshinori Tateishi, Rentaro Oda
No abstract text is available yet for this article.
April 4, 2024: American Journal of Medicine
#39
JOURNAL ARTICLE
Ying C Ku, Mazen Al-Malak, Mychajlo S Kosyk, Ryan Khalaf, Diane Jo, Lianne Mulvihill, Jacob Lammers, Antonio Rampazzo, Bahar Bassiri Gharb
BACKGROUND: The existing diagnostic criteria for septic wrist are nonspecific, exposing patients with noninfectious etiologies to surgical morbidity. This study aimed to identify predictors differentiating septic wrist from other etiologies. METHODS: An institutional review board-approved retrospective review was conducted on patients with a presumed diagnosis of septic wrist (2003-2022). Bivariate and multiple regression analyses were performed to identify correlation between confirmed septic wrist and comorbidities (autoimmune diseases, immunosuppression, crystalline arthropathy, intravenous [IV] drug use, smoking), penetrating trauma, fever, multi-joint involvement, inflammatory markers (erythrocyte sedimentation rate [ESR]/C-reactive protein [CRP]/white blood cells [WBC]), serum uric acid level, blood cultures, imaging findings, and synovial fluid analysis...
March 26, 2024: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
#40
JOURNAL ARTICLE
Antonio Vitiello, Francesco Ferrara, Mariarosaria Boccellino, Annarita Ponzo, Michela Sabbatucci, Andrea Zovi
Antimicrobial resistance is a global public health emergency. The World Health Organization recently highlighted the growing number of new sexually transmitted infections such as gonorrhea, syphilis, and Chlamydia, which are resistant to common antibiotics. The phenomenon is also on the rise due to increasing intercontinental travel. Emerging antibiotic-resistant strains of gonorrhea are particularly associated with international spread from Southeast Asian travelers. Infection with Neisseria gonorrhoeae can cause a wide spectrum of associated diseases such as dermatitis, arthritis and septic arthritis, and pelvic inflammatory disease, and can even lead to serious health consequences for the individual...
April 5, 2024: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
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