Akshay Patel, Edward J Caruana, James Hodson, Rory Morrison, Bo Khor, Savannah Gysling, Jason Trevis, Tobin Mangel, Ruth Benson, Roxanna Zakeri, Jennifer Manders, Ricky Vaja, Luke Rogers, Paul Baker, Dimitri J Pournaras, David Thickett, Martin Hewison, Babu Naidu, Eric Lim
BACKGROUND: There is increasing evidence to suggest vitamin D plays a role in immune and vascular function; hence, it may be of biological and clinical relevance for patients undergoing major surgery. With a greater number of randomised studies being conducted evaluating the impact of vitamin D supplementation on surgical patients, it is an opportune time to conduct further analysis of the impact of vitamin D on surgical outcomes. METHODS: MEDLINE, EMBASE and the Cochrane Trials Register were interrogated up to December 2023 to identify randomised controlled trials of vitamin D supplementation in surgery...
January 17, 2024: BMJ Open