Ping Luo, Qianyi Wang, Peihua Cao, Tianyu Chen, Shengfa Li, Xiaoshuai Wang, Yamin Li, Ze Gong, Yan Zhang, Guangfeng Ruan, Zuoqing Zhou, Yuanyuan Wang, Weiyu Han, Zhaohua Zhu, David J Hunter, Jia Li, Changhai Ding
BACKGROUND: Though anterior cruciate ligament (ACL) tear has been widely accepted as an important accelerator for knee osteoarthritis (KOA), the role of intrinsic ACL degeneration in developing KOA has not been fully investigated. PURPOSE: To determine whether ACL degeneration, in the absence of ACL tear, is associated with incident KOA over 4 years. STUDY DESIGN: Cohort study; Level of evidence, 2. METHODS: Participants' knees in this nested case-control study were selected from the Osteoarthritis Initiative (OAI) study, with Kellgren-Lawrence grading (Kellgren-Lawrence grading) of 0 or 1 at baseline (BL)...
January 2024: Journal of Orthopaedic Translation