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REVIEW
Anika Pulumati, Yanci A Algarin, Sarah Kim, Steven Latta, Jeffrey N Li, Keyvan Nouri
Mohs Micrographic Surgery (MMS) is effective for treating common cutaneous malignancies, but complex repairs may often present challenges for reconstruction. This paper explores the potential of three-dimensional (3D) bioprinting in MMS, offering superior outcomes compared to traditional methods. 3D printing technologies show promise in advancing skin regeneration and refining surgical techniques in dermatologic surgery. A PubMed search was conducted using the following keywords: "Three-dimensional bioprinting" OR "3-D printing" AND "Mohs" OR "Mohs surgery" OR "Surgery...
May 2, 2024: Archives of Dermatological Research
#2
JOURNAL ARTICLE
Magda S Wojtara, Therese M Guinto, Dorcas K Adebogun, Olivier Uwishema
Background TikTok is among the most popular social media sites, and its utilization for health information is growing each day. The present study assesses the popularity and quality of the top 100 most-liked videos on TikTok tagged with "#ichthyosis." This study aims to do so by assessing contributions from physician, and nonphysician sources (such as from patients) to guide healthcare professionals interested in leveraging this platform for public health. Methodology A cross-sectional analysis of the top 100 most-liked videos tagged with "#ichythosis" on TikTok as of January 3, 2024, was conducted...
April 2024: Curēus
#3
JOURNAL ARTICLE
Pedro Gil-Pallares, Maria Eugenia Gil-Pallares, Alba Navarro-Bielsa, Olalla Figueroa-Silva, Laura Taboada-Paz, José Manuel Suárez-Peñaranda
BACKGROUND: Current staging systems have limitations in stratifying high-risk cases of cutaneous squamous cell carcinoma (cSCC). Tumor budding (TB) has emerged as a potential prognostic factor in various cancers. OBJECTIVES: This systematic review and meta-analysis aimed to evaluate the prognostic significance of TB in predicting lymph node metastases (NM) in cSCC. METHODS: A comprehensive search of the PubMed, Web of Science, EMBASE, and Cochrane databases was conducted...
April 30, 2024: Clinical and Experimental Dermatology
#4
REVIEW
Mustafa Mahmood, Daniel Eisen
BACKGROUND: Scalp reconstruction requires knowledge of scalp anatomy and reconstructive options. Advances in the field have led to numerous procedures being at the disposal of the reconstructive surgeon, expanding treatment options for patients. OBJECTIVE: To provide an algorithmic approach and general guidelines to consider when deciding on which scalp surgery will optimize cosmetic and functional outcomes. METHODS & MATERIALS: Previous literature was searched for the last 20 years to provide an updated guide...
April 29, 2024: Archives of Dermatological Research
#5
JOURNAL ARTICLE
C Neuville, B Parratte, S Lombion, F Aubin, I Gallais Sérézal, F Pelletier
BACKGROUND: Vestibulodynia is a highly prevalent chronic pain disorder affecting the vulva having a major impact on women's physical, psychological, and sexual well-being. It remains an underrecognized disease that responds insufficiently to therapies such as physiotherapy and medication. AIM: To assess the global efficacy of first-line therapies and factors associated with treatment escalation in women with vestibulodynia. PATIENTS AND METHODS: This retrospective cohort study was conducted at the dermatology outpatient clinic of the University Hospital in Besancon (France) between 2013 and 2017 and follow-up until 2021...
April 27, 2024: Annales de Dermatologie et de Vénéréologie
#6
JOURNAL ARTICLE
Alberto Soto-Moreno, Carlos Cuenca-Barrales, Salvador Arias-Santiago, José Antonio García-Vidal, Francesc Medina-Mirapeix, Alejandro Molina-Leyva
INTRODUCTION: The recurrent nature of hidradenitis suppurativa (HS), even under maintained systemic treatment, makes it necessary to have effective local treatments; however, the response to these therapies is variable (44-81%). The application of galvanic current (GC) has demonstrated its utility in humans in treating lesions structurally similar to those of HS. With this background, the main objective of this study was to evaluate the efficacy and safety of ultrasound-guided percutaneous GC in inflamed and/or draining tunnels of HS...
April 27, 2024: Dermatology and Therapy
#7
REVIEW
Isabella J Tan, Alicia Podwojniak, Aarushi Parikh, Bernard A Cohen
The evolution of personalized medicine in dermatology signifies a transformative shift towards individualized treatments, driven by the integration of biomarkers. These molecular indicators serve beyond diagnostics, offering insights into disease staging, prognosis, and therapeutic monitoring. Specific criteria guide biomarker selection, ensuring attributes like specificity, sensitivity, cost feasibility, stability, rapid detection, and reproducibility. This literature review, based on data from PubMed, SCOPUS, and Web of Science, explores biomarkers in Hidradenitis Suppurativa (HS), Psoriasis, Atopic Dermatitis (AD), Alopecia Areata (AA), Vitiligo, and Chronic Spontaneous Urticaria (CSU)...
March 30, 2024: Current Issues in Molecular Biology
#8
JOURNAL ARTICLE
Kyu-Ho Yi, Soo-Bin Kim, Fernando Silikovich, Konstantin Frank, Min Ho An, Hee-Jin Kim
INTRODUCTION: The nasal region plays a pivotal role in both facial esthetics and functionality. The use of volumizing fillers has emerged as a potential means to enhance nasal appearance. Preliminary findings from cadaveric studies have highlighted potential risks associated with deeper needle injection, leading to cartilage damage and lateral migration of filler material. Understanding the subcutaneous tissue depth is crucial to prevent such complications and ensure safe filler placement guided by anatomical knowledge...
April 26, 2024: Journal of Cosmetic Dermatology
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JOURNAL ARTICLE
Ahmed Fawzy Rezk, Ahmed Ahmed Touni
BACKGROUND: Acquired melanocytic nevi are common benign skin lesions that require removal under certain circumstances. Shave removal is a straightforward treatment modality with a risk of recurrence. OBJECTIVE: To evaluate the outcome of dermoscopy-guided shave removal of acquired melanocytic nevi in the face of dark-skinned individuals who are more liable to postsurgical complications. METHODS: The study was conducted on 64 patients with acquired facial melanocytic nevi...
May 1, 2024: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
#10
REVIEW
Luis F Andrade, Parsa Abdi, Kayla D Mashoudy, Amritpal Kooner, Ashley Egler, Rebecca Urbonas, Aaron Smith, Gil Yosipovitch
Patient education in atopic dermatitis (AD) has worked in parallel to the gold standard of pharmacological treatment as a foundational component of therapeutic regimens. In addition to improving patient education, past investigations of educational interventions have demonstrated profound reductions in disease severity for patients living with AD. However, prior meta-analytical work has focused mostly on comparing in-person interventions, and thus the need to determine the effectiveness of virtual methodologies in the current post-COVID era remains...
April 25, 2024: Archives of Dermatological Research
#11
JOURNAL ARTICLE
Myfanwy Jenkins, Nicola Watson, Margaret McPhee, Nick J Levell, Mike Arden-Jones, Anthony D Ormerod, Philip J Hampton
Pyoderma gangrenosum (PG) is an ulcerative inflammatory disorder affecting the lower legs in 80% of cases. The use of biologic medications to treat PG is increasing although there is a limited evidence base to guide treatment choices. In some health systems, such as the UK NHS, limitations are placed on biologic prescribing for PG leading to wide variations in prescribing. A survey of mainly UK clinicians showed that prednisolone remains the first line treatment for PG (90%). Biologics have been used by 66% of clinicians as second line therapy but 19% have had prescribing requests declined...
April 25, 2024: Clinical and Experimental Dermatology
#12
REVIEW
Jessica Conley, Jay R Perry, Bruce Ashford, Marie Ranson
Cutaneous squamous cell carcinoma (cSCC) is the second most common malignancy worldwide, with most deaths caused by locally advanced and metastatic disease. Treatment of resectable metastases is typically limited to invasive surgery with adjuvant radiotherapy; however, many patients fail to respond and there is minimal data to predict response or propose effective alternatives. Precision medicine could improve this, though genomic biomarkers remain elusive in the high mutational background and genomic complexity of cSCC...
April 2024: Experimental Dermatology
#13
JOURNAL ARTICLE
Yul Hee Kim, Han-Seul Kim, Hyeung Kyoo Kim, Soo Young Kim, Jeonghun Lee, You Chan Kim, Young Joon Park
PURPOSE: Early intervention of surgical scars with a pulsed dye laser is known to effectively prevent pathologic scars. Despite multiple reports on the effectiveness of the treatment, very few studies have demonstrated its appropriate initiation timing. In this study, our objective was to determine the optimal timing for initiating laser treatment following thyroidectomy. METHODS: This study retrospectively analyzed 91 patients undergoing pulsed dye laser treatment post-thyroidectomy, grouping them by treatment initiation timing...
2024: Clinical, Cosmetic and Investigational Dermatology
#14
JOURNAL ARTICLE
May El Hachem, Andrea Diociaiuti, Giovanna Zambruno, Tonia Samela, Francesca Ferretti, Claudia Carnevale, Renata Linertová, Christine Bodemer, Dédée F Murrell, Damiano Abeni
BACKGROUND: Inherited epidermolysis bullosa (EB) is a clinically and genetically heterogeneous group of skin fragility disorders characterized by blister formation following minor trauma. Four major types are distinguished based on the level of cleavage within the skin. Most EB forms present severely disabling cutaneous and systemic signs and symptoms. Management relies on daily time-consuming and distressing topical medications, and symptomatic treatment of systemic findings. Disease manifestations, symptoms, and daily care strongly affect patient and caregiver quality of life (QoL)...
April 19, 2024: Italian Journal of Pediatrics
#15
EDITORIAL
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April 17, 2024: British Journal of Dermatology
#16
JOURNAL ARTICLE
Wenqi Zhang, Qigen Fang, Xu Zhang, Liyuan Dai, Ruihua Luo, Junhui Yuan
Sentinel lymph node biopsy (SLNB) has gained considerable attention in the management of head and neck cutaneous squamous cell carcinoma (HNcSCC). The aim of this study was to compare the oncologic outcomes between observation and SLNB in cN0 high-risk HNcSCC patients. We retrospectively enrolled patients from the SEER database and evaluated the impact of observation versus SLNB on disease-specific survival (DSS) and overall survival (OS) using a Propensity Score Matching (PSM) analysis. A total of 9804 patients were included, with 1169 cases treated by SLNB...
April 16, 2024: Archives of Dermatological Research
#17
REVIEW
Kevin Jacobsen, Vinzent Kevin Ortner, Emily Wenande, Aditi Sahu, Uwe Paasch, Merete Haedersdal
Non-invasive diagnostics like line-field confocal optical coherence tomography (LC-OCT) are being implemented in dermato-oncology. However, unification of terminology in LC-OCT is lacking. By reviewing the LC-OCT literature in the field of dermato-oncology, this study aimed to develop a unified terminological glossary integrated with traditional histopathology. A PRISMA-guided literature-search was conducted for English-language publications on LC-OCT of actinic keratosis (AK), keratinocyte carcinoma (KC), and malignant melanoma (MM)...
April 2024: Experimental Dermatology
#18
JOURNAL ARTICLE
Ivan Cherrez-Ojeda, Jean Bousquet, Ana Giménez-Arnau, Kiran Godse, Dorota Krasowska, Joanna Bartosińska, Paulina Szczepanik-Kułak, Bartłomiej Wawrzycki, Pavel Kolkhir, Anastasiia Allenova, Andrey Allenov, Sergey Tkachenko, Natasa Teovska Mitrevska, Dragan Mijakoski, Sasho Stoleski, Marta Kolacinska-Flont, Izabela Kuprys-Lipinska, Joanna Molinska, Alicja Kasperska-Zając, Magdalena Zajac, Mateusz Zamlynski, Florin Mihaltan, Ruxandra Ulmeanu, Anna Zalewska-Janowska, Katarzyna Tomaszewska, Mona Al-Ahmad, Maryam Ali Al-Nesf, Tayseer Ibrahim, Sami Aqel, David Pesqué, Mónica Rodríguez-González, Guillermo Hideo Wakida-Kuzunoki, German D Ramon, Gonzalo N Ramon, Sophia Neisinger, Hanna Bonnekoh, Maia Rukhadze, Maryam Khoshkhui, Daria Fomina, Désirée Larenas-Linnemann, Mitja Košnik, Rabia Oztas Kara, Chrystopherson Gengyny Caballero López, Qiang Liu, Carlos Ivancevich Juan, Luis Felipe Ensina, Nelson Rosario, Violeta Kvedariene, Moshe Ben-Shoshan, Roberta Fachini Jardim Criado, Andrea Bauer, Annia Cherrez, Herberto Chong-Neto, Maria Isabel Rojo-Gutierrez, Michael Rudenko, José Ignacio Larco Sousa, Aleksandra Lesiak, Edgar Matos, Nelson Muñoz, Ivan Tinoco, Jaime Moreno, Carolina Crespo Shijin, Romina Hinostroza Logroño, Juan C Sagñay, Marco Faytong-Haro, Karla Robles-Velasco, Torsten Zuberbier, Marcus Maurer
BACKGROUND: Patient-reported outcome measures (PROMs) are validated and standardized tools that complement physician evaluations and guide treatment decisions. PROMs are crucial for monitoring atopic dermatitis (AD) and chronic urticaria (CU) in clinical practice, but there are unmet needs and knowledge gaps regarding their use in clinical practice. OBJECTIVE: We investigated the global real-world use of AD and CU PROMs in allergology and dermatology clinics as well as their associated local and regional networks...
April 9, 2024: Journal of Allergy and Clinical Immunology in Practice
#19
JOURNAL ARTICLE
Emil Ø Ipsen, Jos Dalvad, Anders Koch, Johan S Bundgaad
AIMS: Health research in Greenlanders is challenged by a small population, few dedicated researchers and limited funding. Some research areas have proven impactful but gaps in knowledge are unknown. We aimed to quantify health research in Greenland, providing insights for researchers, policymakers and funding agencies to guide future research. METHODS: We identified all peer-reviewed health research publications with the term 'Greenland***' in title or abstract from 2001 to 2020 through the platform entitled The Lens ...
April 10, 2024: Scandinavian Journal of Public Health
#20
REVIEW
Kevin T Savage, Jeffrey Chen, Kathryn Schlenker, Melissa Pugliano-Mauro, Bryan T Carroll
Longer life expectancy and increasing keratinocyte carcinoma incidence contribute to an increase in geriatric patients presenting for dermatologic surgery. Unique considerations accompany geriatric patients including goals of care, physiologic changes in medication metabolism, cognitive decline, and frailty. Limited geriatric training in dermatology residency has created a knowledge gap and dermatologic surgeons should be familiar with challenges facing older patients to provide interventions more congruent with goals and avoid overtreatment...
April 3, 2024: Journal of the American Academy of Dermatology
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