Emily Stuchfield-Denby, Benjamin De Sainte Marie, Miguel Hie, Yves Hatchuel, Anne Gerber, Saliha Bencheikh, Grégory Pugnet, Matthieu Groh, Meryem-Maud Farhat, Diego Urbina, Mikael Ebbo, Nicolas Schleinitz
INTRODUCTION: IgG4-related disease (IgG4-RD) is a fibro-inflammatory disorder that can affect almost any organ. IgG4-related ophthalmic disease is a protean condition involving the orbit and ocular adnexa. Although a few cases of uveitis have been reported, the exact pattern of IgG4-related intraocular manifestations remains unclear. Here, we report on a nationwide French multicenter cohort of patients with IgG4-RD and uveitis and conducted a literature review. METHODS: Patients with uveitis and a concomitant definite diagnosis of IgG4-RD (Revised Comprehensive Diagnostic criteria, American College of Rheumatology/European League Against Rheumatism classification criteria for IgG4-RD, International Consensus Diagnostic Criteria for auto-immune pancreatitis, or diagnostic criteria for IgG4-related hypophysitis), were screened from our national IgG4-RD and systemic fibrosis database...
November 11, 2023: Seminars in Arthritis and Rheumatism