keyword
https://read.qxmd.com/read/38565143/a-metagenomics-pipeline-reveals-insertion-sequence-driven-evolution-of-the-microbiota
#61
JOURNAL ARTICLE
Joshua M Kirsch, Andrew J Hryckowian, Breck A Duerkop
Insertion sequence (IS) elements are mobile genetic elements in bacterial genomes that support adaptation. We developed a database of IS elements coupled to a computational pipeline that identifies IS element insertions in the microbiota. We discovered that diverse IS elements insert into the genomes of intestinal bacteria regardless of human host lifestyle. These insertions target bacterial accessory genes that aid in their adaptation to unique environmental conditions. Using IS expansion in Bacteroides, we show that IS activity leads to the insertion of "hot spots" in accessory genes...
March 21, 2024: Cell Host & Microbe
https://read.qxmd.com/read/38561774/workforce-strategies-during-the-first-wave-of-the-covid-19-pandemic-a-retrospective-online-survey-at-intensive-care-units-in-germany
#62
JOURNAL ARTICLE
Lara C Stroth, Franziska Jahns, Berit Bode, Maike Stender, Michelle Schmidt, Heiko Baschnegger, Nurith Epstein, Benedikt Sandmeyer, Carla Nau
BACKGROUND: As the COVID-19 pandemic swept across the globe at the beginning of 2020, healthcare systems were forced to rapidly adapt and expand to meet the sudden surge in demand for intensive care services. This study is the first systematic analysis of the strategies employed by German hospitals to recruit personnel and expand bed capacities during the first wave of the pandemic, and to evaluate the effectiveness of those recruitment measures. METHODS: 152 German hospitals with intensive care capacities were selected and invited to participate in an online-based retrospective survey...
April 1, 2024: BMC Health Services Research
https://read.qxmd.com/read/38561762/building-resilience-analysis-of-health-care-leaders-perspectives-on-the-covid-19-response-in-region-stockholm
#63
JOURNAL ARTICLE
Carl Savage, Leonard Tragl, Moa Malmqvist Castillo, Louisa Azizi, Henna Hasson, Carl Johan Sundberg, Pamela Mazzocato
BACKGROUND: The Covid-19 pandemic has tested health care organizations worldwide. Responses have demonstrated great variation and Sweden has been an outlier in terms of both strategy and how it was enacted, making it an interesting case for further study. The aim of this study was to explore how health care leaders experienced the challenges and responses that emerged during the initial wave of the Covid-19 pandemic, and to analyze these experiences through an organizational resilience lens...
April 2, 2024: BMC Health Services Research
https://read.qxmd.com/read/38561158/liquid-liquid-cyclohexanone-cyclohexanol-separation-using-augmented-tight-nanofiltration-membrane-a-sustainable-approach
#64
JOURNAL ARTICLE
Swathi Divakar, Nagaraj S Naik, R Geetha Balakrishna, Mahesh Padaki
Organic solvent nanofiltration (OSN) is an incipient technology in the field of organic liquid-liquid separation. The incomplete separations and complexity involved in these, forces many organic liquids to be released as effluents and the adverse effects of these on environment is enormous and irreparable. The work prominences on the complete separation of industrially significant cyclohexanone: cyclohexanol (keto-alcohol oil) and heptane: toluene mixtures. The separations of these above-mentioned organic liquid mixtures were carried out using the fabricated Lewis acid modified graphitic carbon nitride (Cu2 O@g-C3 N4 ) incorporated polyvinylidene difluoride (PVDF) composite membranes...
March 30, 2024: Chemosphere
https://read.qxmd.com/read/38557799/from-wading-through-treacle-to-making-haste-slowly-a-comprehensive-yet-parsimonious-model-of-drivers-and-challenges-to-implementing-patient-data-sharing-projects-based-on-an-epaccs-evaluation-and-four-pre-existing-literature-reviews
#65
JOURNAL ARTICLE
Mila Petrova, Stephen Barclay
Conceptually, this study aimed to 1) identify the challenges and drivers encountered by England's Electronic Palliative Care Coordination System (EPaCCS) projects in the context of challenges and drivers in other projects on data sharing for individual care (also referred to as Health Information Exchange, HIE) and 2) organise them in a comprehensive yet parsimonious framework. The study also had a strong applied goal: to derive specific and non-trivial recommendations for advancing data sharing projects, particularly ones in early stages of development and implementation...
April 2024: PLOS Digit Health
https://read.qxmd.com/read/38554915/influence-of-para-substituted-benzaldehyde-derivatives-with-different-push-pull-electron-strength-groups-on-the-conformation-of-human-serum-albumin-and-toxicological-effects-in-zebrafish
#66
JOURNAL ARTICLE
Shasha Liu, Long Sun, Mei Sun, Zhanao Lv, Rimao Hua, Yi Wang, Xiaofan Yang, Meiqing Zhu
Excessive intake of benzaldehyde and its derivatives can cause irreversible damage to living organisms. Hence, benzaldehyde derivatives with different para-substitutions of push/pull electronic groups were chosen to investigate the effect of different substituent properties on the structure of human serum albumin (HSA). The binding constants, number of binding sites, major interaction forces, protein structural changes, and binding sites of benzaldehyde (BzH) and its derivatives (4-BzHD) with HSA in serum proteins were obtained based on multispectral and molecular docking techniques...
March 28, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38553492/reliable-water-quality-prediction-and-parametric-analysis-using-explainable-ai-models
#67
JOURNAL ARTICLE
M K Nallakaruppan, E Gangadevi, M Lawanya Shri, Balamurugan Balusamy, Sweta Bhattacharya, Shitharth Selvarajan
The consumption of water constitutes the physical health of most of the living species and hence management of its purity and quality is extremely essential as contaminated water has to potential to create adverse health and environmental consequences. This creates the dire necessity to measure, control and monitor the quality of water. The primary contaminant present in water is Total Dissolved Solids (TDS), which is hard to filter out. There are various substances apart from mere solids such as potassium, sodium, chlorides, lead, nitrate, cadmium, arsenic and other pollutants...
March 29, 2024: Scientific Reports
https://read.qxmd.com/read/38552129/technical-tactical-behavior-analysis-of-general-duty-police-officers-during-non-compliant-suspect-apprehensions-a-novel-approach-to-establish-minimum-force-requirements
#68
JOURNAL ARTICLE
Martin P Poirier, Rachel Blacklock, Michael Cao, Daniel Théoret, Leslie Frei, Patrick Gagnon
BACKGROUND: Public safety relies on the efficient apprehension of non-compliant suspects. However, quantifying the minimum force required to destabilize an actively resistive suspect has remained a challenge. OBJECTIVE: To examine the technical-tactical behaviors of general duty police officers during simulated apprehensions and quantify the minimum force required to destabilize non-compliant suspects. METHODS: Task simulations conducted with 91 officers were analyzed to identify common grappling movements, strikes, control tactics, and changes in body posture...
March 27, 2024: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://read.qxmd.com/read/38545838/general-neurology-current-challenges-and-future-implications
#69
JOURNAL ARTICLE
Claudio Lino Alberto Bassetti, Alice Accorroni, Astri Arnesen, Hamidon Bin Basri, Thomas Berger, Peter Berlit, Paul Boon, Augustina Charway-Felli, Jera Kruja, Steven Lewis, Michael Markowski, Marco Tulio Medina, Pamela McCombe, Elena Moro, Serefnur Ozturk, Paul Smith, Vladimira Vuletic
BACKGROUND AND PURPOSE: In the coming decades, the world will face an increasing burden of neurological disorders (ND) and an urgent need to promote brain health. These challenges contrast with an insufficient neurological workforce in most countries, as well as decreasing numbers of general neurologists and neurologists attracted to work in general neurology (GN). This white paper aims to review the current situation of GN and reflect on its future. METHODS: The European Academy of Neurology (EAN) task force (TF) met nine times between November 2021 and June 2023...
March 28, 2024: European Journal of Neurology
https://read.qxmd.com/read/38545708/weight-excess-among-high-school-students-relation-with-mental-health-and-sociodemographic-factors
#70
JOURNAL ARTICLE
Ferdaous Ouni, Rim Ghammam, Sihem Benfredj, Nawel Zammit, Israr Eleuch, Souhir Chelly, Houda Kalboussi, Jihen Maatoug, Imed Harrabi, Hassen Ghannem
INTRODUCTION: The escalating prevalence of adolescent obesity represents a complex public health challenge, influenced by interactions of environmental, socio-economic, and behavioral factors. Recent studies reveal a surge in addictive substance use among adolescents, with non-substance addictions. Overweight adolescents are particularly susceptible to risky behaviors. Tunisia is not exempt from this issue, facing a rapidly increasing prevalence. AIM: Our work aimed to assess the prevalence of obesity among adolescents and to explore the connections between sociodemographic factors, mental health, and overweight in this demographic group...
March 5, 2024: La Tunisie Médicale
https://read.qxmd.com/read/38541301/chronic-stress-indicator-a-novel-tool-for-comprehensive-stress-analysis
#71
JOURNAL ARTICLE
Matthew Hill, Sayed Mostafa, Emmanuel Obeng-Gyasi
Extensive research has highlighted the strong association between chronic stress and negative health outcomes. This relationship is influenced by various factors, including sociobehavioral, environmental, and genetic and epigenomic forces. To comprehensively assess an individual's stress levels, we propose the development of the Chronic Stress Indicator (CSI), a novel comprehensive multifaceted tool that incorporates key biological, anthropometric, behavioral, and socioeconomic factors. The objective of this study is to assess the effectiveness of the CSI compared to Allostatic Load (AL), a type of chronic stress, in identifying health issues related to stress...
March 5, 2024: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/38540652/work-related-stress-and-psychological-distress-among-law-enforcement-officers-the-carolina-blue-project
#72
JOURNAL ARTICLE
Nayeon Lee, Ya-Ke Wu
Law enforcement is a stressful occupation that places significant psychological demands on those serving in this role. However, little is known about the severity of work-related stress and psychological distress among law enforcement officers (LEOs) in North Carolina (NC). This cross-sectional study examined the severity of work-related stress and psychological distress among 283 LEOs in NC. The Maslach Burnout Inventory, the Operational Police Stress Questionnaire, the Depression, Anxiety, and Stress Scale, and the Post-Traumatic Stress Disorder (PTSD) Checklist were used to assess burnout, operational police stress, depression, anxiety, stress, and PTSD among LEOs...
March 19, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38537714/perfect-cooperative-pest-control-via-nano-pesticide-and-natural-predator-high-predation-selectivity-and-negligible-toxicity-toward-predatory-stinkbug
#73
JOURNAL ARTICLE
Shangyuan Wu, Qinhong Jiang, Zhilin Xia, Zhirong Sun, Qing Mu, Chunyang Huang, Fan Song, Meizhen Yin, Jie Shen, Hu Li, Shuo Yan
The improper use of synthetic pesticides has caused adverse effects on global ecosystems and human health. As a part of sustainable pest management strategy, natural predators, along with nano-pesticides, have made significant contributions to ecological agriculture. The cooperative application of both approaches may overcome their limitations, substantially reducing pesticide application while controlling insect pests efficiently. Herein, the current study introduced a cationic star polymer (SPc) to prepare two types of nano-pesticides, which were co-applied with predatory stinkbugs (Picromerus lewisi) to achieve perfect cooperative pest control...
March 25, 2024: Chemosphere
https://read.qxmd.com/read/38537602/-the-provision-of-assisted-death-in-the-context-of-the-desire-to-anticipate-death
#74
JOURNAL ARTICLE
Xavier Busquet-Duran, Emilio José Martínez Losada, Pere Torán-Monserrat
The entry into force of the Organic Law on the Regulation of Euthanasia in June 2021 obliges clinicians to reconsider their professional work, in the face of a new service that expands the limits of what was considered correct until then. This new service affects the entire healthcare system, but especially primary care professionals. Beyond the procedural and moral aspects, it is necessary to rethink the assessment of the patient who expresses a wish to die. In this review, we start with the relatively recent definition of the wish to hasten death (WTHD), its causes, epidemiology and differential diagnosis...
March 26, 2024: Atencion Primaria
https://read.qxmd.com/read/38536172/adolescent-cardiorespiratory-fitness-and-future-work-ability
#75
JOURNAL ARTICLE
Perttu T T Laakso, Francisco B Ortega, Pertti Huotari, Asko J Tolvanen, Urho M Kujala, Timo T Jaakkola
IMPORTANCE: Although research indicates that low fitness in youth is associated with a higher risk of chronic disability in men, the association of fitness in adolescence with work ability in working men and women remains unknown. OBJECTIVE: To examine the associations of adolescent health-related physical fitness with future work ability. DESIGN, SETTING, AND PARTICIPANTS: This 45-year observational cohort study, conducted in Finland, examined the direct and indirect longitudinal associations of objectively measured health-related fitness in adolescence (in 1976) with self-reported work ability and sickness absence in early middle age (in 2001) and the Work Ability Index in late middle age (in 2021)...
March 4, 2024: JAMA Network Open
https://read.qxmd.com/read/38531821/the-coronovirus-19-pandemic-and-the-future-of-work
#76
JOURNAL ARTICLE
Chidimma Ogechukwu Ezeilo, Judith Green-McKenzie
INTRODUCTION: The "Future of Work" refers to workplace modifications projected to occur after pandemics, other large-scale events that affect the health and safety of broad sectors of the workforce, technological advancements, or shifts in the economy. This paper examines the influence of the COVID-19 pandemic on the Future of Work. METHODS: The electronic databases PubMed, Google Scholar and Scopus were explored using search terms such as "post-pandemic", "working force" and "future of work" for papers published between 2000 to 2023...
March 27, 2024: Journal of Occupational and Environmental Medicine
https://read.qxmd.com/read/38527745/long-term-trends-in-the-work-hours-of-physicians-in-canada
#77
JOURNAL ARTICLE
Boris Kralj, Rabiul Islam, Arthur Sweetman
BACKGROUND: Physician work hours directly influence patient access to health care services and play a vital role in physician human resource planning. We sought to evaluate long-term trends in hours worked by physicians in Canada, overall and by subgroup. METHODS: We used Statistics Canada's Labour Force Survey to identify physicians via occupation and industry coding information. We estimated descriptive statistics and performed graphical analysis of the average weekly hours worked by physicians over the 1987-2021 period...
March 24, 2024: Canadian Medical Association Journal: CMAJ
https://read.qxmd.com/read/38527186/post-traumatic-stress-symptoms-and-predictors-among-spanish-police-and-armed-forces-during-the-covid-19-pandemic-in-spain
#78
JOURNAL ARTICLE
Susana Gracia-Lanchares, Helena Garrido-Hernansaiz, Nereida Bueno-Guerra, Rocío Rodríguez-Rey
OBJECTIVE: To assess the psychological impact of the COVID-19 crisis on the police and armed forces. METHODS: Participants (N = 242) completed an online survey that assessed post-traumatic stress symptoms (PTSS), burnout, emotional suppression, and labour and sociodemographic variables. Mean difference, correlation, and stepwise linear regression tests were performed. RESULTS: One-third of participants showed severe PTSS, linked to patrolling duties, very frequent contact with other people, fear of contagion, perceived pandemic severity, living with at-risk people, taking a COVID-19 test, working more than normal, suffering an assault, having little vacation, and having to distance from loved ones...
March 26, 2024: Journal of Occupational and Environmental Medicine
https://read.qxmd.com/read/38527176/evolving-global-responses-to-the-pandemic-sustaining-interprofessional-education-and-collaborative-practice
#79
JOURNAL ARTICLE
Sylvia Langlois, Camila Mendes da Silva Souza, Andreas Xyrichis, Mukadder Inci Baser Kolcu, Dean Lising, Ghaidaa Najjar, Hossein Khalili
The COVID-19 pandemic created global disruption in health professions education and healthcare practice, necessitating an abrupt move to digital delivery. A longitudinal survey was conducted to track the evolution of global responses to the pandemic. During the initial stages, educational and health institutions were forced to adapt quickly without careful consideration of optimal pedagogy, practices, and effectiveness of implemented approaches. In this paper, we report the results of Phase 3 of the global survey that was distributed between November 2021 and February 2022 through InterprofessionalResearch...
March 25, 2024: Journal of Interprofessional Care
https://read.qxmd.com/read/38524960/exploring-psychiatrists-experiences-during-transition-from-mental-health-act-1987-to-mental-healthcare-act-2017-in-goa-india
#80
JOURNAL ARTICLE
Rohan Vanagundi, Sneha Pokle, Rohit Walwaikar, Shilpa Waikar
BACKGROUND: Mental Healthcare Act 2017 (MHCA) came into force on 29 May 2018. Goa State Mental Health Authority (GSMHA) notified the Mental Health Review Board on 8 February 2022, completing the important process of implementation of the act. The transition comes with challenges. METHODS: A qualitative study was conducted with 18 practicing psychiatrists who had worked under Mental Health Act 1987 as well as MHCA 2017 through purposive sampling across Goa. Data was collected through individual interviews; analysis was done by Braune and Clarke's framework of Thematic Analysis...
January 2024: Indian Journal of Psychological Medicine
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