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JOURNAL ARTICLE
Hanna Tigerstrand Grevnerts, Christine Delisle Nyström, Jairo Hidalgo Migueles, Marie Löf
There is a well-established relationship between physical activity (PA) and physical fitness in children, being the latter an important marker for present and future health; however, there is still insufficient knowledge for the transition from the preschool age to early childhood. Therefore, this study in Swedish children aimed to investigate the estimated effect of meeting the aerobic component of the PA guidelines at 4 and/or 9 years of age on physical fitness measured at 9 years of age. PA was assessed using a wrist-worn ActiGraph accelerometer and identical data processing in 217 healthy children in Sweden (114 boys and 103 girls)...
April 2024: Scandinavian Journal of Medicine & Science in Sports
#22
JOURNAL ARTICLE
Silvia Helena De Bortoli Cassiani, Bruna Moreno Dias, Brenda Elizabeth Meléndez Romero, Jairo Rivera
OBJECTIVE: Identify and analyze the role of nursing professionals in the development and care of adolescent health in Honduras, by analyzing the curricular content of the training provided to nursing students with respect to adolescent health, and by studying policies on adolescent health. METHODS: Mixed methods study, with a sequential explanatory approach, carried out from May to July 2023 through surveys of nursing schools, analysis of policy documents, a survey with nursing professionals, and a focus group...
2024: Pan American Journal of Public Health
#23
JOURNAL ARTICLE
Vanessa Silva de Souza, Liciane Fernandes Medeiros, Dirson João Stein, Camila Lino de Oliveira, Helouise Richardt Medeiros, Jairo Alberto Dussan-Sarria, Wolnei Caumo, Andressa de Souza, Iraci L S Torres
OBJECTIVES: Despite the fact that fibromyalgia, a widespread disease of the musculoskeletal system, has no specific treatment, patients have shown improvement after pharmacological intervention. Pregabalin has demonstrated efficacy; however, its adverse effects may reduce treatment adherence. In this context, neuromodulatory techniques such as transcranial direct current stimulation (tDCS) may be employed as a complementary pain-relieving method. Consequently, the purpose of this study was to evaluate the effect of pregabalin and tDCS treatments on the behavioral and biomarker parameters of rats submitted to a fibromyalgia-like model...
January 1, 2024: Scandinavian Journal of Pain
#24
JOURNAL ARTICLE
Jonathan Ramírez-Prada, Juan S Rocha-Ortiz, Marta I Orozco, Pedro Moreno, Miguel Guevara, Mauricio Barreto, Maria E Burbano, Sara Robledo, Maria Del Pilar Crespo-Ortiz, Jairo Quiroga, Rodrigo Abonia, Viviana Cuartas, Braulio Insuasty
New pyridine-based chalcones 4a-h and pyrazolines 5a-h (N-acetyl), 6a-h (N-phenyl), and 7a-h (N-4-chlorophenyl) were synthesized and evaluated by the National Cancer Institute (NCI) against 60 different human cancer cell lines. Pyrazolines 6a, 6c-h, and 7a-h satisfied the pre-determined threshold inhibition criteria, obtaining that compounds 6c and 6f exhibited high antiproliferative activity, reaching submicromolar GI50 values from 0.38 to 0.45 μM, respectively. Moreover, compound 7g (4-CH3 ) exhibited the highest cytostatic activity of these series against different cancer cell lines from leukemia, nonsmall cell lung, colon, ovarian, renal, and prostate cancer, with LC50 values ranging from 5...
March 28, 2024: Archiv der Pharmazie
#25
JOURNAL ARTICLE
Jairo Alonso Hernández, Juliana Rodríguez, Gabriel Rendón, Lina Maria Trujillo, María Islena Beltrán, Carolina Mantilla, Carolina Echeverry, María Angélica Mendoza, Mónica Gil, Marcela Núñez, Marcela Hernández, Jonathan Peralta, René Pareja
OBJECTIVE: To compare the pelvic lymph node involvement and risk of recurrence in patients with human papillomavirus (HPV)-associated endocervical adenocarcinoma stage IA2-IB1 undergoing hysterectomy and/or trachelectomy plus lymphadenectomy, according to Silva's classification system. METHODS: A retrospective cohort study was performed in two Colombian cancer centers. The cases were classified according to the Silva classification system. Clinical, surgical, and histopathological variables were evaluated...
March 28, 2024: International Journal of Gynaecology and Obstetrics
#26
JOURNAL ARTICLE
Elizabeth Shedroff, Maria Laura Martin, Shannon L M Whitmer, Julia Brignone, Jorge B Garcia, Carina Sen, Yael Nazar, Cintia Fabbri, Maria Morales-Betoulle, Jairo Mendez, Joel Montgomery, Maria Alejandra Morales, John D Klena
Following an Argentine Hemorrhagic Fever (AHF) outbreak in the early 1990s, a rodent survey for Junín virus, a New World Clade B arenavirus, in endemic areas of Argentina was conducted. Since 1990, INEVH has been developing eco-epidemiological surveillance of rodents, inside and outside the Argentine Hemorrhagic Fever endemic area. Samples from rodents captured between 1993 and 2019 that were positive for Arenavirus infection underwent Sanger and unbiased, Illumina-based high-throughput sequencing, which yielded 5 complete and 88 partial Mammarenaviruses genomes...
February 22, 2024: Viruses
#27
JOURNAL ARTICLE
Ana María Pello Lázaro, Koldo Villelabeitia Jaureguizar, Juan Antonio Franco Peláez, Ana Venegas-Rodriguez, Álvaro Aceña, Andrea Kallmeyer, Ester Cánovas, María Luisa González-Casaus, Nieves Tarín, Carmen Cristóbal, Carlos Gutiérrez-Landaluce, Ana Huelmos, Óscar González-Lorenzo, Joaquín Alonso, Lorenzo López-Bescós, Jesús Egido, Ignacio Mahillo-Fernández, Jairo Lumpuy-Castillo, Óscar Lorenzo, José Tuñón
Background : Mineral metabolism (MM), mainly fibroblast growth factor-23 (FGF-23) and klotho, has been linked to cardiovascular (CV) diseases. Cardiac rehabilitation (CR) has been demonstrated to reduce CV events, although its potential relationship with changes in MM is unknown. Methods : We performed a prospective, observational, case-control study, with acute coronary syndrome (ACS) patients who underwent CR and control patients (matched by age, gender, left ventricular ejection fraction, diabetes, and coronary artery bypass grafting), who did not...
March 14, 2024: Journal of Clinical Medicine
#28
JOURNAL ARTICLE
Arij Akir, Abrar Senhaji-Kacha, Maria Carmen Muñoz-Egea, Jaime Esteban, John Jairo Aguilera-Correa
BACKGROUND: The Mycobacterium avium complex includes the commonest non-tuberculous mycobacteria associated with human infections. These infections have been associated with the production of biofilms in many cases, but there are only a few studies about biofilms produced by the species included in this group. METHODS: Three collection strains ( M. avium ATCC25291, M. intracellulare ATCC13950, and M. chimaera DSM756), three clinically significant strains (647, 657, and 655), and three clinically non-significant ones (717, 505, and 575) of each species were included...
March 16, 2024: Antibiotics
#29
JOURNAL ARTICLE
Jhon Jairo Melchor-Moncada, Alejandra García-Barco, Augusto Zuluaga-Vélez, Luz Angela Veloza, Juan Carlos Sepúlveda-Arias
Serratiopeptidase, a bacterial metalloprotease known for its pain-relieving and anti-inflammatory properties, can be produced through fermentation with S. marcescens . This study aimed to identify key factors related to nutrient composition and physicochemical conditions for production in Erlenmeyer flasks and to scale up the mixture to a bioreactor to obtain the maximum proteolytic activity. A Plackett-Burman design was used to determine whether the presence of silkworm pupae (at 1.5%) was a significant parameter for serratiopeptidase production...
February 25, 2024: Methods and Protocols
#30
JOURNAL ARTICLE
María Camila Machado-Aguilera, Leonardo Lemus-Mejía, Jairo Pérez-Torres, Diego A Zárrate-Charry, Andrés Arias-Alzate, José F González-Maya
The jaguar (Panthera onca) is a charismatic species considered Vulnerable in Colombia but yet largely unknown in the country. The species is mostly threatened by the continuous decline in its habitats, mostly derived from deforestation and habitat loss, additional to hunting and conflicts with humans. Thus, the future of jaguars in Colombia depends on protecting and recovering existing habitats. The aims of this study were to 1) evaluate jaguar distribution and identify the remnant patches of habitat in Colombia, 2) define an ecological connectivity network within the country, and 3) propose a priority areas portfolio for the conservation and recovery of jaguars...
2024: PloS One
#31
JOURNAL ARTICLE
Analía Burgueño, Marta Giovanetti, Vagner Fonseca, Noelia Morel, Mauricio Lima, Emerson Castro, Natália R Guimarães, Felipe C M Iani, Victoria Bormida, Maria Noel Cortinas, Viviana Ramas, Leticia Coppola, Ana I Bento, Leticia Franco, Jairo Mendez Rico, José Lourenço, Luiz Carlos Junior Alcantara, Hector Chiparelli
Uruguay experienced its first Chikungunya virus outbreak in 2023, resulting in a significant burden to its healthcare system. We conducted analysis based on real-time genomic surveillance (30 novel whole genomes) to offer timely insights into recent local transmission dynamics and eco-epidemiological factors behind its emergence and spread in the country.
March 22, 2024: Emerging Microbes & Infections
#32
REVIEW
J Manuel Matiz-González, Jesús A Ballesteros-Ballesteros, María Hernández, Julián A Mejorano-Fonseca, Claudia Cuervo, Álvaro A Faccini-Martínez, Marylin Hidalgo, Jairo Pérez-Torres, Carlos Ramiro Silva-Ramos
INTRODUCTION: Bats are a diverse group of mammals that have unique features allowing them to act as reservoir hosts for several zoonotic pathogens such as Leptospira. Leptospires have been classified into pathogenic, intermediate, and saprophytic groups and more recently into clades P1, P2, S1, and S2, being all the most important pathogenic species related to leptospirosis included within the P1/pathogenic clade. Leptospira has been detected from bats in several regions worldwide; however, the diversity of leptospires harboured by bats is still unknown...
March 20, 2024: Zoonoses and Public Health
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JOURNAL ARTICLE
Aileen Y Chang, Sarah R Tritsch, Carlos Andres Herrera Gomez, Liliana Encinales, Andres Cadena Bonfanti, Wendy Rosales, Evelyn Mendoza-Torres, Samuel Simmens, Richard L Amdur, Christopher N Mores, Paige Fierbaugh, Carlos Alberto Perez Hernandez, Geraldine Avendaño, Paula Bruges Silvera, Yerlenis Galvis Crespo, Alberto David Cabana Jimenez, Jennifer Carolina Martinez Zapata, Dennys Jimenez, Estefanie Osorio-Llanes, Jairo Castellar-Lopez, Karol Suchowiecki, Karen Martins, Melissa Gregory, Ivan Zuluaga, Abigale Proctor, Alfonso Sucerquia Hernández, Leandro Sierra-Carrero, Maria Villanueva Colpas, Juan Carlos Perez Hernandez, Andres Alberto Figueroa Quast, Joaquin Andres Calderon De Barros, José Forero Mejía, Johan Penagos Ruiz, David Boyle, Gary S Firestein, Gary L Simon
OBJECTIVE: To define the relationship between chronic chikungunya post-viral arthritis disease severity, cytokine response and T cell subsets in order to identify potential targets for therapy. METHODS: Participants with chikungunya arthritis were recruited from Colombia from 2019-2021. Arthritis disease severity was quantified using the Disease Activity Score-28 and an Arthritis-Flare Questionnaire adapted for chikungunya arthritis. Plasma cytokine concentrations (interleukin (IL)-1β, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12p70, IL-13, interferon-γ and tumor necrosis factor (TNF)) were measured using a Meso Scale Diagnostics assay...
2024: PloS One
#34
JOURNAL ARTICLE
Hugo Azcorra, Alina Dione Marin-Cardenas, Jairo R Villanueva-Toledo, Nina Mendez-Dominguez
Background: Over the years, there has been a noticeable increase in the incidence of multiple pregnancies, due in part to the increased use of assisted reproductive technologies in recent years. The increase in twin pregnancies constitutes a public health challenge due to the adverse outcomes sometimes they entail. Twin pregnancies inherently carry a higher risk of complications, and one of the critical associated factors is the risk of low birth weight. Twin birth weight discordance among different populations can be attributed to differences in non-shared environmental influences...
December 2024: Journal of Maternal-fetal & Neonatal Medicine
#35
JOURNAL ARTICLE
Aline D Purificação, Sabrina Silva-Mendonça, Luiza V Cruz, Carolina Q Sacramento, Jairo R Temerozo, Natalia Fintelman-Rodrigues, Caroline Souza de Freitas, Bruna Fleck Godoi, Miguel Menezes Vaidergorn, Juliana Almeida Leite, Luis Carlos Salazar Alvarez, Murillo V Freitas, Meryck F B Silvac, Bianca A Martin, Renata F V Lopez, Bruno J Neves, Fabio T M Costa, Thiago M L Souza, Flavio da Silva Emery, Carolina Horta Andrade, M Cristina Nonato
The urgent need for effective treatments against emerging viral diseases, driven by drug-resistant strains and new viral variants, remains critical. We focus on inhibiting the human dihydroorotate dehydrogenase ( Hs DHODH), one of the main enzymes responsible for pyrimidine nucleotide synthesis. This strategy could impede viral replication without provoking resistance. We evaluated naphthoquinone fragments, discovering potent Hs DHODH inhibition with IC50 ranging from 48 to 684 nM, and promising in vitro anti-SARS-CoV-2 activity with EC50 ranging from 1...
March 12, 2024: ACS Omega
#36
JOURNAL ARTICLE
Daniel Arroyo-Sánchez, Francisco Javier Gil-Etayo, Jairo Eduardo Niño Ramírez, Isabel Jiménez-Hernaz, Amalia Tejeda Velarde
Two nucleotide substitutions in intronic regions give rise to the novel alleles: HLA-B*35:01:01:39 and -B*35:03:01:32.
March 2024: HLA
#37
JOURNAL ARTICLE
Sofia Silva La Rocca de Freitas, Laís Velloso Garcia, Jairo Antonio Melo Dos Santos, Líria Queiroz Luz Hirano
Blood gas analysis reflects the exchange of oxygen and carbon dioxide in the lungs. This test provides important information, since the relationship between these gases has a direct impact on the acid-basic balance in the body. Given the significance of blood gas analysis in Brazilian reptiles, this study set out to establish temperature-corrected and uncorrected reference intervals for venous blood gas measurements in Chelonoidis carbonarius, and to compare values between females and males. In this study, 19 animals were used, 8 males and 11 females...
2024: PloS One
#38
REVIEW
Jairo Andrés Camaño Echavarría, Sarah El Hajj, Rachel Irankunda, Katalin Selmeczi, Cédric Paris, Chibuike C Udenigwe, Laetitia Canabady-Rochelle
Metal-chelating peptides, which form metal-peptide coordination complexes with various metal ions, can be used as biofunctional ingredients notably to enhance human health and prevent diseases. This review aims to discuss recent insights into food-derived metal-chelating peptides, the strategies set up for their discovery, their study, and identification. After understanding the overall properties of metal-chelating peptides, their production from food-derived protein sources and their potential applications will be discussed, particularly in nutritional, cosmetics and pharmaceutical fields...
March 15, 2024: Food & Function
#39
JOURNAL ARTICLE
Mirta Crovetto, Samuel Durán-Aguero, Solange Parra-Soto, Tannia Valeria Carpio-Arias, Edna J Nava-González, Saby Mauricio-Alza, Leslie Landaeta-Díaz, Melissa Miranda-Durán, Jhon Jairo Bejarano-Roncancio, Sonia Ivankovich Guillén, María Vitullo, Otilia Perichart-Perera, Shelia Cerezo de Ríos, Karla Cordón-Arrivillaga, Beatriz Núñez-Martínez, Gloria Maricela Morales-Morales, Eliana Romina Meza Miranda
BACKGROUND: At hospital level, clinical nutritionists play a fundamental role in health recovery, contributing to shorter hospital stays and addressing hospital malnutrition. However, in Latin America no studies have been conducted on the activities of the nutritionist and the factors influencing their performance. AIMS: to describe the activities of the clinical nutritionist in public and private hospital settings in Latin America and to determine the factors associated with disciplinary practice...
April 2024: Clinical Nutrition ESPEN
#40
JOURNAL ARTICLE
Marta Flor-Alemany, Johanna Sandborg, Jairo H Migueles, Emmie Söderström, Maria Henström, Nuria Marín-Jiménez, Laura Baena-García, Virginia A Aparicio, Marie Löf
This study aimed to examine the association of Mediterranean diet (MD) adherence and MD components with health-related quality of life (HRQoL) in pregnant women from Spain and Sweden. A total of 138 pregnant women from Spain (age: 32.9 ± 4.6 years old) and 302 pregnant women from Sweden (age: 31.3 ± 4.1 years old) were included. MD adherence was assessed with the Mediterranean food pattern (i.e., a MD index) at the 14-16th gestational weeks. HRQoL was assessed with the Spanish and Swedish versions of the 36-item Short-Form Health Survey (SF-36 and RAND-36, respectively) at the 14-16th and 34-37th gestational weeks...
March 1, 2024: Nutrients
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