Stijn W de Jonge, Rick H Hulskes, Maedeh Zokaei Nikoo, Robert P Weenink, Christian S Meyhoff, Kate Leslie, Paul Myles, Andrew Forbes, Robert Greif, Ozan Akca, Andrea Kurz, Daniel I Sessler, Janet Martin, Marcel Gw Dijkgraaf, Kane Pryor, F Javier Belda, Carlos Ferrando, Gabriel M Gurman, Christina M Scifres, David S McKenna, Matthew Tv Chan, Pascal Thibon, Jannicke Mellin-Olsen, Benedetta Allegranzi, Marja Boermeester, Markus W Hollmann
INTRODUCTION: The use of high fraction of inspired oxygen (FiO2 ) intraoperatively for the prevention of surgical site infection (SSI) remains controversial. Promising results of early randomised controlled trials (RCT) have been replicated with varying success and subsequent meta-analysis are equivocal. Recent advancements in perioperative care, including the increased use of laparoscopic surgery and pneumoperitoneum and shifts in fluid and temperature management, can affect peripheral oxygen delivery and may explain the inconsistency in reproducibility...
October 29, 2023: BMJ Open