Di Zhang, Dong Xu, Xiaobo Huang, Yingqi Wei, Fuxin Tang, Xiusen Qin, Weiwen Liang, Zhongping Liang, Lin Jin, Hui Wang, Huaiming Wang
Pelvic organ prolapse (POP) is one of the most common pelvic floor dysfunction disorders worldwide. The weakening of pelvic connective tissues initiated by excessive collagen degradation is a leading cause of POP. However, the patches currently used in the clinic trigger an unfavorable inflammatory response, which often leads to implantation failure and the inability to simultaneously reverse progressive collagen degradation. Therefore, to overcome the present challenges, a new strategy is applied by introducing puerarin (Pue) into poly(l-lactic acid) (PLLA) using electrospinning technology...
March 21, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)