Yanwei Cheng, Xue Cao, Jiange Zhang, Lijun Xu, Lijie Qin
BACKGROUND: Emergency Departments (EDs) play a crucial role in providing immediate medical care, particularly in densely populated countries like China. While previous research has predominantly focused on well-funded urban hospitals, this study offers a comprehensive evaluation of EDs in county-level public hospitals in Henan province, China, aiming to identify disparities and challenges. METHODS: A descriptive cross-sectional survey was conducted in 382 public hospitals across Henan province, China, from July 1, 2023, to August 1, 2023...
2023: Frontiers in Public Health
Eva Maria Peer, Jonas Quitt, Stephan Marsch, Gregor Loosen
In an adolescent patient with severe yew intoxication and consecutive cardiac arrest, non-responsive to conventional resuscitation necessitating extracorporeal life support, Levosimendan has been implemented in the early acute phase of hemodynamic stabilization, without obvious side effects. However, the additive value of this treatment in severe yew intoxication remains speculative.
December 2023: Clinical Case Reports
Nida Qadir, Sarina Sahetya, Laveena Munshi, Charlotte Summers, Darryl Abrams, Jeremy Beitler, Giacomo Bellani, Roy G Brower, Lisa Burry, Jen-Ting Chen, Carol Hodgson, Catherine L Hough, Francois Lamontagne, Anica Law, Laurent Papazian, Tai Pham, Eileen Rubin, Matthew Siuba, Irene Telias, Setu Patolia, Dipayan Chaudhuri, Allan Walkey, Bram Rochwerg, Eddy Fan
BACKGROUND: This document updates previously published Clinical Practice Guidelines for the management of patients with acute respiratory distress syndrome (ARDS), incorporating new evidence addressing the use of corticosteroids, venovenous extracorporeal membrane oxygenation, neuromuscular blocking agents, and positive end-expiratory pressure (PEEP). METHODS: We summarized evidence addressing four "PICO questions" (patient, intervention, comparison, and outcome)...
November 30, 2023: American Journal of Respiratory and Critical Care Medicine
(no author information available yet)
No abstract text is available yet for this article.
November 28, 2023: Journal of Thoracic and Cardiovascular Surgery
Yael Lichter, Amir Gal Oz, Uri Carmi, Nimrod Adi, Asaph Nini, Yoel Angel, Andrey Nevo, Daniel Aviram, Itay Moshkovits, Noam Goder, Dekel Stavi
BACKGROUND: The exposure of blood to the artificial circuit during extracorporeal membrane oxygenation (ECMO) can induce an inflammatory response. C-reactive protein (CRP) is a commonly used biomarker of systemic inflammation. METHODS: In this retrospective observational study, we analyzed results of daily plasma CRP measurements in 110 critically ill patients, treated with ECMO. We compared CRP levels during the first 5 days of ECMO operation, between different groups of patients according to ECMO configurations, Coronavirus disease 2019 (COVID-19) status, and mechanical ventilation parameters...
November 29, 2023: International Journal of Artificial Organs
Derrick Tam, Hollie Norman, Leon L Chen
The onset of the COVID-19 pandemic has led to an increased use of extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS); however, there are ongoing concerns about its associated risks and benefits, making a comprehensive understanding vital for clinical decision-making. This review aims to evaluate the efficacy, risks, and practical implications of ECMO as a therapeutic intervention in severe ARDS secondary to COVID-19. The results indicate that ECMO is a key therapeutic intervention for managing severe COVID-19, but due to its associated risks and resource constraints, its application needs careful consideration...
January 2024: Critical Care Nursing Quarterly
Tasnim F Imran, Feven Ataklte, Mahnoor Khalid, Diana Lopez, Donya Mohebali, Natalie A Bello, J Michael Gaziano, Luc Djousse, Zolt Arany, Marwa A Sabe, Katharine French, Athena Poppas, Wen-Chih Wu, Gaurav Choudhary
AIMS: We sought to identify factors associated with right ventricular (RV) dysfunction and elevated pulmonary artery systolic pressure (PASP) and association with adverse outcomes in peripartum cardiomyopathy (PPCM). METHODS AND RESULTS: We conducted a multi-centre cohort study to identify subjects with PPCM with the following criteria: left ventricular ejection fraction (LVEF) < 40%, development of heart failure within the last month of pregnancy or 5 months of delivery, and no other identifiable cause of heart failure with reduced ejection fraction...
November 29, 2023: ESC Heart Failure
Federica Magni, Rossana Soloperto, Anita Farinella, Elisa Bogossian, Katarina Halenarova, Zoe Pletschette, Mariangela Gozza, Vincent Labbe', Walter Ageno, Fabio Silvio Taccone, Filippo Annoni
AIM: Although brain injury is the main determinant of poor outcome following cardiac arrest (CA), cardiovascular failure is the leading cause of death within the first days after CA. However, it remains unclear which hemodynamic parameter is most suitable for its early recognition. We investigated the association of cardiac power output (CPO) with early mortality in intensive care unit(ICU) after CA and with mortality related to post-CA cardiovascular failure. METHODS: Retrospective analysis of adult comatose survivors of CA admitted to the ICU of a University Hospital...
November 27, 2023: Resuscitation
Koichi Toda, Junya Ako, Atsushi Hirayama, Koichiro Kinugawa, Yoshio Kobayashi, Minoru Ono, Takashi Nishimura, Naoki Sato, Takahiro Shindo, Morimasa Takayama, Satoshi Yasukochi, Akira Shiose, Yoshiki Sawa
Fulminant myocarditis requiring peripheral veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has a high mortality rate. We investigated clinical outcomes of combined use of VA-ECMO and percutaneous left ventricular assist device (VAD) (Impella) for fulminant myocarditis in 104 consecutive patients enrolled in the Japan Registry for Percutaneous VAD (J-pVAD) between October 2017 and January 2020. Patients were followed until hospital discharge and predictors of survival were analyzed with a Cox proportional hazards model...
November 23, 2023: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Michael R Chomat, Kerry Swanson, Kevin Barton, Matthew Douds, Ahmed S Said
The use of bivalirudin as the primary anticoagulant for children supported on extracorporeal membrane oxygenation (ECMO) is growing. Ideal management of bivalirudin dosing during therapeutic plasma exchange (TPE) on ECMO is unknown. We performed a single-center retrospective study of ECMO patients anticoagulated with bivalirudin who underwent TPE from January 2019 to December 2021. Therapeutic plasma exchange sessions were analyzed individually by bivalirudin dosing strategy (no change [NC] versus increased dose [dose change {DC} bivalirudin group]) and replacement fluid (all fresh-frozen plasma [FFP] versus all albumin or FFP and albumin [FFP/Albumin])...
November 23, 2023: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Ryan L Kobayashi, Robert Przybylski, Kimberlee Gauvreau, Paul Esteso, Meena Nathan, Francis Fynn-Thompson, Sarah A Teele
Despite extracorporeal membrane oxygenation (ECMO) utilization in nearly 20% of cases, there are limited data in children with acute fulminant myocarditis (AFM) requiring ECMO. Herein we identify risk factors for death or heart transplant (HT) in children with AFM supported with ECMO, describe our experience with left atrial (LA) decompression, and depict long-term outcomes of survivors. We performed a retrospective cohort of patients <18 years with AFM (≤14 days of symptoms, rapid cardiogenic shock, and normal left ventricular [LV] size on presentation) supported with ECMO admitted to a single intensive care unit from 1997 to 2021...
November 22, 2023: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Xiaoshu Zuo, Xiaoyu Fang, Guang Li, Liying Zhan
No abstract text is available yet for this article.
October 31, 2023: J Intensive Med
Yonghao Xu, Yin Xi, Shuijiang Cai, Yuheng Yu, Sibei Chen, Weijie Guan, Weibo Liang, Hongkai Wu, Weiqun He, Xilong Deng, Yuanda Xu, Rong Zhang, Manshu Li, Jieyi Pan, Zhenting Liang, Ya Wang, Shaofeng Kong, Xiaoqing Liu, Zheng Lv, Yimin Li
BACKGROUND: Venovenous extracorporeal membrane oxygenation (VV-ECMO) has been demonstrated to be effective in treating patients with virus-induced acute respiratory distress syndrome (ARDS). However, whether the management of ECMO is different in treating H1N1 influenza and coronavirus disease 2019 (COVID-19)-associated ARDS patients remains unknown. METHODS: This is a retrospective cohort study. We included 12 VV-ECMO-supported COVID-19 patients admitted to The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Eighth People's Hospital, and Wuhan Union Hospital West Campus between January 23 and March 31, 2020...
October 31, 2023: J Intensive Med
Loic Le Guennec, Nicolas Weiss
The central nervous system is characterized by a peculiar vascularization termed blood-brain barrier (BBB), which regulates the exchange of cells and molecules between the cerebral tissue and the whole body. BBB dysfunction is a life-threatening condition since its presence corresponds to a marker of severity in most diseases encountered in the intensive care unit (ICU). During critical illness, inflammatory response, cytokine release, and other phenomena activating the brain endothelium contribute to alterations in the BBB and increase its permeability to solutes, cells, nutrients, and xenobiotics...
October 31, 2023: J Intensive Med
Miguel Alvarez Villela, Danni Fu, Kylie Roslin, Rebecca Smoller, Daniel Asemota, Daniel J Miklin, Arber Kodra, Sirish Vullaganti, Robert O Roswell, Sabarivinoth Rangasamy, Christina E Saikus, Zachary N Kon, Matthew J Pierce, Gregg Husk, Gerin R Stevens, Simon Maybaum
BACKGROUND: Expert opinion and professional society statements have called for multi-tier care systems for the management of cardiogenic shock (CS). However, little is known about how to pragmatically define centers with different levels of care (LOC) for CS. METHODS: Eleven of 23 hospitals within our healthcare system sharing a common electronic health record were classified as different LOC according to their highest mechanical circulatory support (MCS) capabilities: Level 1 (L-1)-durable left ventricular assist device, Level 1A (L-1A)-extracorporeal membrane oxygenation, Level 2 (L-2)-intra-aortic balloon pump and percutaneous ventricular assist device; and Level 3 (L-3)-no MCS...
2023: Frontiers in Cardiovascular Medicine
Miri Horimoto, Masahiro Tsutsui, Nobuhiro Mochizuki, Yuki Setogawa, Fumitaka Suzuki, Masahiko Narita, Aina Hirofuzi, Shingo Kunioka, Tomonori Shirasaka, Natsuya Ishikawa, Hiroyuki Kamiya
Acute coronary syndrome with cardiogenic shock is a life-threatening condition, but with planned staged treatment combined with coronary revascularization and mechanical circulatory supports its management is increasingly possible. Here, we present our successful life-saving case. A 76-year-old male patient was diagnosed with ST-elevation myocardial infarction with cardiogenic shock due to severe stenosis of the left main coronary artery based on the severe triple vessel disease. We initially introduced Impella CP and performed a percutaneous coronary intervention without stenting on the patient...
November 2023: Journal of Surgical Case Reports
Dong Yun Lee, SuRak Eo, SooA Lim, Jung Soo Yoon
INTRODUCTION: Deep sternal wound infection (DSWI) is a serious complication that may occur after median sternotomy, with potentially devastating consequences. By reporting our case and analyzing the existing literature, this article aimed to provide a thorough understanding of the role of negative-pressure wound therapy (NPWT) and the importance of flap choice in managing DSWI accompanied by severe heart injury and high hemodynamic risk. CASE DESCRIPTION: A 60-year-old woman with severe aortic stenosis, aortic valve regurgitation, and heart failure underwent redo sternotomy, which resulted in an intraoperative right ventricle injury...
2023: Frontiers in Surgery
Caleb R Weissman, Stephane Leung Wai Sang
We present here a unique case in which a 63-year-old man developed diffuse coronary vasospasm on postoperative day (POD) 1 following uneventful aortic valve replacement, replacement of ascending aorta, and coronary artery bypass. Subsequent emergent coronary angiogram demonstrated diffuse native coronary artery vasospasm that was only transiently responsive to intracardiac nitroglycerin, resulting in persistent cardiogenic shock and severe biventricular dysfunction. The patient was, thus, placed on femoral-femoral venoarterial (VA) extracorporeal membrane oxygenation (ECMO) with Impella support...
2023: Case Reports in Cardiology
Syed Jalil, Ashraf Ahmed, Mahmoud Abdalla, Mohammed Al-Hijji
BACKGROUND: Rheumatic fever is still a major cause of mitral valve (MV) stenosis in the developing world. Few patients with critical rheumatic MV stenosis can present with acute cardiogenic shock (CS) that requires urgent treatment with circulatory support and definitive valvular repair or replacement. CASE SUMMARY: A 37-year-old gentleman was admitted with heart failure, CS Society for Cardiovascular Angiography and Interventions D, and atrial fibrillation with a rapid ventricular response...
November 2023: European Heart Journal. Case Reports
Luke B Jackson, Michal J Sobieszczyk, James K Aden, Joseph E Marcus
BACKGROUND: Fever and leukocytosis are 2 parameters commonly cited in clinical practice as indications to perform an infectious workup in patients receiving extracorporeal membrane oxygenation (ECMO), but their utility is unknown. METHODS: All patients who received ECMO between December 2014 and December 2020 with influenza or COVID-19 were included in this retrospective cohort study. Cultures were included if they were drawn from patients without signs of decompensation...
November 2023: Open Forum Infectious Diseases
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.