Yogesh Khachane, Robert Halliday, Gordon Thomas, Rajesh Maheshwari, Kathryn Browning Carmo
AIM: To report the outcome for infants with congenital diaphragmatic hernia (CDH) and identify clinical factors affecting outcome from a tertiary perinatal surgical campus where extracorporeal membrane oxygenation (ECMO) is available however rarely utilised. METHODS: A retrospective cohort study of infants with CDH born in a co-located perinatal neonatal intensive care unit (NICU) or retrieved into and managed at a surgical NICU: 2003-2018. RESULTS: One hundred and fifty-nine infants with CDH were identified...
July 22, 2021: Journal of Paediatrics and Child Health
John W Stokes, James M Katsis, Whitney D Gannon, Todd W Rice, Robert J Lentz, Otis B Rickman, Sameer K Avasarala, Clayne Benson, Matthew Bacchetta, Fabien Maldonado
OBJECTIVES: Practice patterns for the use of extracorporeal membrane oxygenation (ECMO) during high-risk airway interventions vary, and data are limited. We aim to characterize our recent experience using ECMO for procedural support during whole-lung lavage (WLL) and high-risk bronchoscopy for central airway obstruction (CAO). METHODS: We performed a retrospective cohort study of adults who received ECMO during WLL and high-risk bronchoscopy from 1 July 2018 to 30 March 2020...
July 19, 2021: Interactive Cardiovascular and Thoracic Surgery
Shuanglei Li, Jing Xiong, Zhongtao Du, Wei Lai, Xinhua Ma, Zhichun Feng, Yuan Shi, Xiaoyang Hong, Yundai Chen
PURPOSE: The role of extracorporeal membrane oxygenatio (ECMO) for rescue therapy of respiratory failure in critically ill coronavirus disease 2019 (COVID-19) patients remains controversial. We aimed to evaluate the clinical outcomes of ECMO in the treatment of COVID-19 compared with conventional ventilation support. METHODS: In this retrospective cohort study, data were collected on extremely critical patients with COVID-19 from January 2020 to March 2020 in intensive care unit of a hospital in charge by national rescue team in Wuhan, China, the epicenter of pandemic...
July 22, 2021: Journal of Cardiac Surgery
Xiaolong Zhang, Yiyong Fu, Guang Yue, Sheng Yang, Rong Ju
Bedside lung ultrasound may be an effective method for the assessment of lung recruitment in newborns with extracorporeal membrane oxygenation (ECMO). We report a case of a neonate who had severe hypoxemia with persistent pulmonary hypertension and massive pneumothorax due to meconium aspiration syndrome and was treated with ECMO. Positive pressure mechanical ventilation resulted in persistent massive air leakage from the disrupted pulmonary tissue. When ECMO was initiated, a "total lung rest" ventilation strategy was used to facilitate healing of the lung rupture and absorption of the pneumothorax...
July 22, 2021: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
Christina Scharf, Ines Schroeder, Michael Paal, Martin Winkels, Michael Irlbeck, Michael Zoller, Uwe Liebchen
BACKGROUND: A cytokine storm is life threatening for critically ill patients and is mainly caused by sepsis or severe trauma. In combination with supportive therapy, the cytokine adsorber Cytosorb® (CS) is increasingly used for the treatment of cytokine storm. However, it is questionable whether its use is actually beneficial in these patients. METHODS: Patients with an interleukin-6 (IL-6) > 10,000 pg/ml were retrospectively included between October 2014 and May 2020 and were divided into two groups (group 1: CS therapy; group 2: no CS therapy)...
July 22, 2021: Annals of Intensive Care
Jayakumar Sreenivasan, Sagar Ranka, Shubham Lahan, Ahmed Abu-Haniyeh, Heyi Li, Risheek Kaul, Aaqib Malik, Wilbert S Aronow, William H Frishman, Steven Lansman
Coronavirus disease 2019 (COVID-19) is characterized by a clinical spectrum of diseases ranging from asymptomatic or mild cases to severe pneumonia with acute respiratory distress syndrome (ARDS) requiring mechanical ventilation. Extracorporeal membrane oxygenation (ECMO) has been used as rescue therapy in appropriate patients with COVID-19 complicated by ARDS refractory to mechanical ventilation. In this study, we review the indications, challenges, complications and clinical outcomes of ECMO utilization in critically ill patients with COVID-19 related ARDS...
July 20, 2021: Cardiology in Review
Ryosuke Kowatari, Norihiro Kondo, Shuto Watanabe, Kazuyuki Daitoku, Masahito Minakawa
A 74-year-old woman developed inferior myocardial infarction due to right coronary artery occlusion and underwent percutaneous coronary intervention. Two days later, echocardiography revealed ventricular septal rupture, and Impella CP was inserted to avoid emergency surgery. However, the patient's hemodynamics deteriorated rapidly, necessitating additional venoarterial extracorporeal membranous oxygenation support with concomitant Impella support (ECPELLA). The ventricular septal rupture was surgically repaired using the extended sandwich technique via a right ventricular approach; the ascending aorta was clamped with the clampable portion of the Impella...
July 21, 2021: Journal of Cardiac Surgery
Amédée Ego, Olivier Taton, Alexandre Brasseur, Yves Laurent, Fabio Silvio Taccone, Romain Courcelle
OBJECTIVES: Venovenous extracorporeal membrane oxygenation has been largely used in patients with refractory acute respiratory distress syndrome due to coronavirus disease 2019. Few data on long-term pulmonary function among venovenous extracorporeal membrane oxygenation survivors are available. DESIGN: Retrospective, observational cohort. SETTING: Two mixed medical-surgical tertiary (30 beds) and secondary (22 beds) ICUs. PATIENTS: All critically ill adult coronavirus disease 2019 survivors treated with venovenous extracorporeal membrane oxygenation between March 10, and April 30, 2020...
July 2021: Critical care explorations
Jess Pedrina, John Stambas
Each year, hundreds of thousands of individuals succumb to influenza virus infection and its associated complications. Several preventative and therapeutic options may be applied in order to preserve life. These traditional approaches include administration of seasonal influenza vaccines, pharmacological interventions in the form of antiviral drug therapy and supportive clinical approaches including mechanical ventilation and extracorporeal membrane oxygenation. While these measures have shown varying degrees of success, antiviral therapies and vaccination are constrained due to ongoing antigenic drift...
2021: Frontiers in Molecular Biosciences
Raphael Joye, Dimitri Ceroni, Maurice Beghetti, Yacine Aggoun, Tornike Sologashvili
Kingella kingae is a gram-negative coccobacillus belonging to the HACEK group ( Haemophilus species, Aggregatibacter actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens , and Kingella species) and is a common oropharyngeal colonizer of healthy young children. Osteoarticular infection is the most commonly reported invasive Kingella kingae infection in children, usually presenting a mild clinical picture. However, it can also cause severe invasive infections, especially infective endocarditis, with a high complication rate...
2021: Frontiers in Pediatrics
Alexandra Schou, Jesper Mølgaard, Lars Willy Andersen, Søren Holm, Marc Sørensen
During 50 years of extracorporeal life support (ECLS), this highly invasive technology has left a considerable imprint on modern medicine, and it still confronts researchers, clinicians and policymakers with multifarious ethical challenges. After half a century of academic discussion about the ethics of ECLS, it seems appropriate to review the state of the argument and the trends in it. Through a comprehensive literature search on PubMed, we identified three ethical discourses: (1) trials and evidence accompanying the use of ECLS, (2) ECLS allocation, decision-making and limiting care, and (3) death on ECLS and ECLS in organ donation...
July 21, 2021: Critical Care: the Official Journal of the Critical Care Forum
Gangping Huang, Huaidong Chen, Weimin Zhang, Fan He
No abstract text is available yet for this article.
July 2021: Arquivos Brasileiros de Cardiologia
Adam Fabiani, Eugenia Dal Bo, Stefano Di Bella, Marco Gabrielli, Alessandro Bologna, Umberto Albert, Gianfranco Sanson
Leptospirosis is a zoonosis caused by infection with pathogenic strains of the bacterium Leptospira. The disease can be complicated by pulmonary hemorrhages and acute respiratory distress syndrome, with the mortality rate increasing to 51-100%. We report the case of a 37-year-old man who was admitted to the emergency department with a 6-day history of fever, weakness, vomiting and diarrhea, followed by jaundice. On admission, he presented leukocytosis, thrombocytopenia and acute liver and kidney injuries. His clinical course was critical, as it was immediately complicated by sepsis and severe respiratory failure, requiring haemodialysis, mechanical ventilation and broad-spectrum antibiotic therapy...
July 5, 2021: Infectious Disease Reports
Dinçer Yıldızdaş, Nagehan Aslan
Objective: In this study, we have planned to present the results of a national survey performed to evaluate the last situation of pediatric intensive care specialty and pediatric intensive care units in Turkey. Material and Methods: We have sent an electronic survey which includes 47 questions about the characteristics of pediatric intensive care units, staff, and equipment to members of the Turkish Society of Pediatric Emergency and Intensive Care via email. Results: A total of 58 participant units responded to our survey...
March 2021: Turkish archives of pediatrics
Nawaporn Assanangkornchai, Douglas Slobod, Rayan Qutob, May Tam, Jason Shahin, Gordan Samoukovic
Implantation of venovenous extracorporeal membrane oxygenation as an alternative to invasive mechanical ventilation, an "awake approach," may facilitate a lung- and diaphragm-protective ventilatory strategies without the associated harms of endotracheal intubation, positive pressure ventilation, and continuous sedation. This report presents the characteristics and outcomes of the patients treated with the awake venovenous extracorporeal membrane oxygenation approach. DESIGN: Retrospective case series...
July 2021: Critical care explorations
Saarth Shiralkar, James Fletcher, Madhu Balasubramaniam
We present a case of a young woman who was admitted to the hospital with persistent pneumonia and cough productive of purulent green sputum. She was admitted to the intensive care unit due to type 1 respiratory failure. Chest computerised tomography (CT) showed a large right-sided hydropneumothorax, for which a right-sided chest drain was inserted. Despite intubation, oxygenation continued to deteriorate and the patient was commenced on veno-venous extracorporeal membrane oxygenation (ECMO) and transferred to the regional ECMO centre...
June 2021: Curēus
John Kyle Bohman, Scott D Nei, Laurie N Mellon, Robert Spencer Ashmun, Pramod K Guru
OBJECTIVES: This study aimed to determine whether patients on extracorporeal membrane oxygenation (ECMO) with coronavirus disease 2019 (COVID-19) achieved lower rates of physical therapy participation and required more sedation than those on ECMO without COVID-19. DESIGN: Retrospective, observational, matched-cohort study. SETTING: Bicenter academic quaternary medical centers. PARTICIPANTS: All adults on ECMO for severe COVID-19-associated acute respiratory distress syndrome (ARDS) during 2020 and matched (matched 1:1 based on age ± 15 years and medical center) adults on ECMO for ARDS not associated with COVID-19...
June 29, 2021: Journal of Cardiothoracic and Vascular Anesthesia
Jonah Rubin, Katharine E Black, Robert W Hallowell, Alison S Witkin, Melissa Lydston, Kenneth Shelton, Jerome Crowley, Yehuda Vogel, Yuval Raz
No abstract text is available yet for this article.
July 17, 2021: Chest
Christian Karagiannidis, Stephan Strassmann, Michaela Merten, Thomas Bein, Wolfram Windisch, Patrick Meybohm, Steffen Weber-Carstens
No abstract text is available yet for this article.
July 20, 2021: American Journal of Respiratory and Critical Care Medicine
Elona Rrapo Kaso, Jonathan A Pan, Michael Salerno, Alexandra Kadl, Chad Aldridge, Ziv J Haskal, Jamie L W Kennedy, Sula Mazimba, Andrew D Mihalek, Nicholas R Teman, Jay Giri, Herbert D Aronow, Aditya M Sharma
Venoarterial extracorporeal membrane oxygenation (ECMO) has been used to treat acute massive pulmonary embolism (PE) patients. However, the incremental benefit of ECMO to standard therapy remains unclear. Our meta-analysis objective is to compare in-hospital mortality in patients treated for acute massive PE with and without ECMO. The National Library of Medicine MEDLINE (USA), Web of Science, and PubMed databases from inception through October 2020 were searched. Screening identified 1002 published articles...
July 19, 2021: Journal of Cardiovascular Translational Research
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