keyword
https://read.qxmd.com/read/31583827/becoming-cognitive-science
#21
JOURNAL ARTICLE
Robert L Goldstone
Cognitive science continues to make a compelling case for having a coherent, unique, and fundamental subject of inquiry: What is the nature of minds, where do they come from, and how do they work? Central to this inquiry is the notion of agents that have goals, one of which is their own persistence, who use dynamically constructed knowledge to act in the world to achieve those goals. An agentive perspective explains why a special class of systems have a cluster of co-occurring capacities that enable them to exhibit adaptive behavior in a complex environment: perception, attention, memory, representation, planning, and communication...
October 2019: Topics in Cognitive Science
https://read.qxmd.com/read/31571482/single-electron-lanthanide-lanthanide-bonds-inside-fullerenes-toward-robust-redox-active-molecular-magnets
#22
JOURNAL ARTICLE
Fupin Liu, Lukas Spree, Denis S Krylov, Georgios Velkos, Stanislav M Avdoshenko, Alexey A Popov
A characteristic phenomenon of lanthanide-fullerene interactions is the transfer of metal valence electrons to the carbon cage. With early lanthanides such as La, a complete transfer of six valence electrons takes place for the metal dimers encapsulated in the fullerene cage. However, the low energy of the σ-type Ln-Ln bonding orbital in the second half of the lanthanide row limits the Ln2 → fullerene transfer to only five electrons. One electron remains in the Ln-Ln bonding orbital, whereas the fullerene cage with a formal charge of -5 is left electron-deficient...
October 1, 2019: Accounts of Chemical Research
https://read.qxmd.com/read/31499559/amputations-versus-salvage-reconciling-the-differences
#23
JOURNAL ARTICLE
Cara K Black, Laurel D Ormiston, Kenneth L Fan, Vikas S Kotha, Christopher Attinger, Karen Kim Evans
BACKGROUND:  There are many factors to consider when choosing between amputations versus salvage in lower extremity reconstructive surgery. Postoperative functionality and survival benefit are critical factors when deciding between limb salvage and amputation. METHODS:  In this review, we present the evidence and the risks and benefits between these two options in the setting of the acute, trauma population and the chronic, diabetes population. RESULTS:  The trauma population is on average young without significant comorbidities and with robust vasculature and core strength for recovery...
September 9, 2019: Journal of Reconstructive Microsurgery
https://read.qxmd.com/read/31273863/effect-of-24-week-strength-training-on-unstable-surfaces-on-mobility-balance-and-concern-about-falling-in-older-adults
#24
JOURNAL ARTICLE
André Luiz Torres Pirauá, Bruno Remígio Cavalcante, Valéria Mayaly Alves de Oliveira, Natália Barros Beltrão, Gabriel de Amorim Batista, Ana Carolina Rodarti Pitangui, David Behm, Rodrigo Cappato de Araújo
OBJECTIVE: To evaluate the effects of 24 weeks of strength training on stable (ST) and unstable surfaces (UST) on the functional mobility, balance, and concern about falling in healthy older adults, younger than 70. DESIGN: A single-center randomized clinical trial. PARTICIPANTS: Sixty-four older adults (58 females and 6 males; 68 years) were randomized into control, ST, or UST groups. INTERVENTIONS: Both ST and UST intervention groups received a core muscle, upper, and lower limb moderate-intensity strength exercises using stable and unstable surfaces...
July 4, 2019: Scandinavian Journal of Medicine & Science in Sports
https://read.qxmd.com/read/31069505/complex-pattern-formation-driven-by-the-interaction-of-stable-fronts-in-a-competition-diffusion-system
#25
JOURNAL ARTICLE
Lorenzo Contento, Masayasu Mimura
The ecological invasion problem in which a weaker exotic species invades an ecosystem inhabited by two strongly competing native species is modelled by a three-species competition-diffusion system. It is known that for a certain range of parameter values competitor-mediated coexistence occurs and complex spatio-temporal patterns are observed in two spatial dimensions. In this paper we uncover the mechanism which generates such patterns. Under some assumptions on the parameters the three-species competition-diffusion system admits two planarly stable travelling waves...
May 8, 2019: Journal of Mathematical Biology
https://read.qxmd.com/read/30860424/tests-to-measure-core-stability-in-laboratory-and-field-settings-reliability-and-correlation-analyses
#26
JOURNAL ARTICLE
Francisco J Vera-Garcia, Diego López-Plaza, Casto Juan-Recio, David Barbado
Although core stability (CS) has been assessed through many different tests, the relationships among them are currently unknown. The main objective was to analyze the relationship between 5 representative tests used to assess CS in: (1) laboratory settings: Sudden Loading Test (SLT) and Stable and Unstable Sitting Test (SUST) and (2) field settings: Biering-Sørensen Test (BST), 3-Plane Core Strength Test, and Double-Leg Lowering Test. The reliability of these tests was also examined. In total, 33 recreationally active males performed the tests twice...
June 1, 2019: Journal of Applied Biomechanics
https://read.qxmd.com/read/30687433/effects-of-core-strength-training-using-stable-and-unstable-surfaces-on-physical-fitness-and-functional-performance-in-professional-female-futsal-players
#27
JOURNAL ARTICLE
Carlos Lago-Fuentes, Ezequiel Rey, Alexis Padrón-Cabo, Alejandro Sal de Rellán-Guerra, Ana Fragueiro-Rodríguez, Javier García-Núñez
The aim of this study was to assess the effect of core strength training performed on a stable surface (CTS) compared with core strength training performed on an unstable surface (CTU) on physical fitness (jump performance, sprint, and repeated sprint ability (RSA)) and quality of movement (Fundamental Movement Screen) in professional female futsal players. Fourteen professional female futsal players (mean age: 23.7 ± 5.1 years, age range: 18-28 years) were randomly assigned to a CTS (n = 7) or a CTU (n = 7) group...
December 2018: Journal of Human Kinetics
https://read.qxmd.com/read/29997737/field-test-performance-of-junior-competitive-surf-athletes-following-a-core-strength-training-program
#28
JOURNAL ARTICLE
Tracy A Axel, Jill A Crussemeyer, Kevyn Dean, Douglas E Young
Lower body and core muscular strength are essential for optimal performance in many sports and competitive surfers have similar strength demands when maneuvering a surfboard to achieve competition success. Presently, the use of unstable surfaces is excessively utilized by surf coaches and trainers and to date, research does not support this as an effective training method for long-term improvements. Therefore, the purpose of this study was to determine the effectiveness of an 8-week Core Strength Training Program (CSTP) on a battery of field tests specific to assessing core musculature and lower body strength for junior competitive surf athletes...
2018: International Journal of Exercise Science
https://read.qxmd.com/read/29659982/transcription-start-site-analysis-reveals-widespread-divergent-transcription-in-d-melanogaster-and-core-promoter-encoded-enhancer-activities
#29
JOURNAL ARTICLE
Sarah Rennie, Maria Dalby, Marta Lloret-Llinares, Stylianos Bakoulis, Christian Dalager Vaagensø, Torben Heick Jensen, Robin Andersson
Mammalian gene promoters and enhancers share many properties. They are composed of a unified promoter architecture of divergent transcripton initiation and gene promoters may exhibit enhancer function. However, it is currently unclear how expression strength of a regulatory element relates to its enhancer strength and if the unifying architecture is conserved across Metazoa. Here we investigate the transcription initiation landscape and its associated RNA decay in Drosophila melanogaster. We find that the majority of active gene-distal enhancers and a considerable fraction of gene promoters are divergently transcribed...
June 20, 2018: Nucleic Acids Research
https://read.qxmd.com/read/29596533/pluripotency-gene-network-dynamics-system-views-from-parametric-analysis
#30
JOURNAL ARTICLE
Ilya R Akberdin, Nadezda A Omelyanchuk, Stanislav I Fadeev, Natalya E Leskova, Evgeniya A Oschepkova, Fedor V Kazantsev, Yury G Matushkin, Dmitry A Afonnikov, Nikolay A Kolchanov
Multiple experimental data demonstrated that the core gene network orchestrating self-renewal and differentiation of mouse embryonic stem cells involves activity of Oct4, Sox2 and Nanog genes by means of a number of positive feedback loops among them. However, recent studies indicated that the architecture of the core gene network should also incorporate negative Nanog autoregulation and might not include positive feedbacks from Nanog to Oct4 and Sox2. Thorough parametric analysis of the mathematical model based on this revisited core regulatory circuit identified that there are substantial changes in model dynamics occurred depending on the strength of Oct4 and Sox2 activation and molecular complexity of Nanog autorepression...
2018: PloS One
https://read.qxmd.com/read/28256219/mapping-the-broad-structural-and-mechanical-properties-of-amyloid-fibrils
#31
JOURNAL ARTICLE
Guillaume Lamour, Roy Nassar, Patrick H W Chan, Gunes Bozkurt, Jixi Li, Jennifer M Bui, Calvin K Yip, Thibault Mayor, Hongbin Li, Hao Wu, Jörg A Gsponer
Amyloids are fibrillar nanostructures of proteins that are assembled in several physiological processes in human cells (e.g., hormone storage) but also during the course of infectious (prion) and noninfectious (nonprion) diseases such as Creutzfeldt-Jakob and Alzheimer's diseases, respectively. How the amyloid state, a state accessible to all proteins and peptides, can be exploited for functional purposes but also have detrimental effects remains to be determined. Here, we measure the nanomechanical properties of different amyloids and link them to features found in their structure models...
February 28, 2017: Biophysical Journal
https://read.qxmd.com/read/27908012/pt-symmetric-couplers-with-competing-cubic-quintic-nonlinearities
#32
JOURNAL ARTICLE
Gennadiy Burlak, Salomon Garcia-Paredes, Boris A Malomed
We introduce a one-dimensional model of the parity-time ( PT)-symmetric coupler, with mutually balanced linear gain and loss acting in the two cores, and nonlinearity represented by the combination of self-focusing cubic and defocusing quintic terms in each core. The system may be realized in optical waveguides, in the spatial and temporal domains alike. Stationary solutions for PT-symmetric solitons in the systems are tantamount to their counterparts in the ordinary coupler with the cubic-quintic nonlinearity, where the spontaneous symmetry breaking of solitons is accounted for by bifurcation loops...
November 2016: Chaos
https://read.qxmd.com/read/27475953/core-stability-in-athletes-a-critical-analysis-of-current-guidelines
#33
REVIEW
Klaus Wirth, Hagen Hartmann, Christoph Mickel, Elena Szilvas, Michael Keiner, Andre Sander
Over the last two decades, exercise of the core muscles has gained major interest in professional sports. Research has focused on injury prevention and increasing athletic performance. We analyzed the guidelines for so-called functional strength training for back pain prevention and found that programs were similar to those for back pain rehabilitation; even the arguments were identical. Surprisingly, most exercise specifications have neither been tested for their effectiveness nor compared with the load specifications normally used for strength training...
March 2017: Sports Medicine
https://read.qxmd.com/read/27232602/trunk-stability-trunk-strength-and-sport-performance-level-in-judo
#34
JOURNAL ARTICLE
David Barbado, Alejandro Lopez-Valenciano, Casto Juan-Recio, Carlos Montero-Carretero, Jaap H van Dieën, Francisco J Vera-Garcia
Although trunk muscle function has been suggested to be a determinant of judo performance, its contribution to high-level performance in this sport has been poorly studied. Therefore, several tests were used to assess the differences in trunk muscle function between 11 international and 14 national level judo practitioners (judokas). Trunk strength and endurance were assessed using isokinetic tests and core stability was assessed using two protocols: 1) sudden loading, to assess trunk responses to unexpected external perturbations; 2) stable and unstable sitting, to assess the participants' ability to control trunk balance...
2016: PloS One
https://read.qxmd.com/read/26651628/phase-behavior-near-and-beyond-the-thermodynamic-stability-threshold
#35
JOURNAL ARTICLE
Gianpietro Malescio, Santi Prestipino
The phase behavior of stabilized dispersions of macromolecules is most easily described in terms of the effective interaction between the centers of mass of solute particles. For molecules such as polymer chains, dendrimers, etc., the effective pair potential is finite at the origin, allowing "particles" to freely interpenetrate each other. Using a double-Gaussian model (DGM) for demonstration, we study the behavior of the system as a function of the attraction strength η. Above a critical strength η(c), the infinite-size system is Ruelle unstable, in that it collapses to a cluster of finite volume...
November 2015: Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
https://read.qxmd.com/read/26504350/impact-of-post-manipulation-corrective-core-exercises-on-the-spinal-deformation-and-lumbar-strength-in-golfers-a-case-study
#36
JOURNAL ARTICLE
Chul-Ho Shin, Minjeong Kim, Gi Duck Park
[Purpose] This study examined spinal shape in professional golfers with chronic back pain, and analyzed the effects of a 4-week regimen of semi-weekly manipulation and corrective core exercises on spinal shape. [Subjects] Two golfers with chronic back pain. [Methods] The pelvis and spinal vertebrae were corrected using the Thompson "drop" technique. Angle and force were adjusted to place the pelvis, lumbar spine, and thoracic vertebrae in neutral position. The technique was applied twice weekly after muscle massage in the back and pelvic areas...
September 2015: Journal of Physical Therapy Science
https://read.qxmd.com/read/26147126/working-with-socially-and-medically-complex-patients-when-care-transitions-are-circular-overlapping-and-continual-rather-than-linear-and-finite
#37
JOURNAL ARTICLE
Shauna R Roberts, Jane Crigler, Cristina Ramirez, Deborah Sisco, Gerald L Early
The care coordination program described here evolved from 5 years of trial and learning related to how to best serve our high-cost, high-utilizing, chronically ill, urban core patient population. In addition to medical complexity, they have daily challenges characteristic of persons served by Safety-Net health systems. Many have unstable health insurance status. Others have insecure housing. A number of patients have a history of substance use and mental illness. Many have fractured social supports. Although some of the best-known care transition models have been successful in reducing rehospitalizations and cost among patients studied, these models were developed for a relatively high functioning patient population with social support...
July 2015: Journal for Healthcare Quality: Official Publication of the National Association for Healthcare Quality
https://read.qxmd.com/read/26045469/interplay-between-intrinsic-point-defects-and-low-angle-grain-boundary-in-bcc-tungsten-effects-of-local-stress-field
#38
JOURNAL ARTICLE
Liang-Liang Niu, Ying Zhang, Xiaolin Shu, Shuo Jin, Hong-Bo Zhou, Fei Gao, Guang-Hong Lu
We have used molecular statics in conjunction with an embedded atom method to explore the interplay between native point defects (vacancies and self-interstitials (SIAs)) and a low-angle grain boundary (GB) in bcc tungsten. The low-angle GB has biased absorption of SIAs over vacancies. We emphasize the significance of phenomena such as vacancy delocalization and SIA instant absorption around the GB dislocation cores in stabilizing the defect structures. Interstitial loading into the GB can dramatically enhance the interaction strength between the point defects and the GB due to SIA clustering (SIA cloud formation) or SIA vacancy recombination...
July 1, 2015: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://read.qxmd.com/read/26001286/a-novel-biological-role-for-nsltp2-from-oriza-sativa-potential-incorporation-with-anticancer-agents-nucleosides-and-their-analogues
#39
JOURNAL ARTICLE
Mojtaba Tousheh, Fatemeh Zahra Darvishi, Mehran Miroliaei
Development of a protein-based drug delivery system has major impact on the efficacy and bioavailability of unstable and water insoluble drugs. In the present study, the binding modes of a nonspecific lipid transfer protein (nsLTP2) from Oryza sativa with various nucleosides and analogous molecules were identified. The 3-D structure of the protein was designed and validated using modeler 9.13, Molegro virtual docker and procheck tool, respectively. The binding affinity and strength of interactions, key contributing residues and specificity toward the substrates were accomplished by computational docking and model prediction...
October 2015: Computational Biology and Chemistry
https://read.qxmd.com/read/25931767/the-effect-of-complex-rehabilitation-training-for-12-weeks-on-trunk-muscle-function-and-spine-deformation-of-patients-with-sci
#40
JOURNAL ARTICLE
Dong-Hun Sung, Seong-Deok Yoon, Gi Duck Park
[Purpose] It is important for patients with incomplete spinal cord injury (SCI) to strengthen their muscle strength and return to the work force one of the ultimate objectives of rehabilitation. This study reports how a single patient with SCI became stabilized in terms of abdominal muscles and back extension muscles, as well as returning the back to the neutral position from spinal deformation, as result of complex exercises performed for 12 weeks. [Subjects] The degree of damage of the subject was rated as C grade...
March 2015: Journal of Physical Therapy Science
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