keyword
https://read.qxmd.com/read/38536523/suitability-of-reduced-dose-glucocorticoids-therapy-regimen-for-antibody-associated-vasculitis-patients-with-tb-a-retrospective-study
#21
JOURNAL ARTICLE
Rui Wen, Jingni Xiao, Ning Ding, Yong Zhong, Qiong Yuan, Jiali Li, Qi Wang, Hebin Xie, Jiao Qin
INTENTION: Immunosuppressive therapy is the major treatment approach for patients with anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV). Due to impaired cellular immunological function and the use of glucocorticoids and immunosuppressants, AAV patients are predisposed to opportunistic infections, including tuberculosis (TB). This retrospective study aims to analyze the clinical characteristics of patients with AAV and TB and explore suitable glucocorticoid regimens for them...
March 27, 2024: European Journal of Clinical Microbiology & Infectious Diseases
https://read.qxmd.com/read/38536499/incidence-of-heterotopic-ossification-following-total-hip-arthroplasty-by-approach-a-systematic-review
#22
JOURNAL ARTICLE
Rex Herzberg, Olivia C Tracey, Shahriar Tahvilian, Nayeem Baksh, Bashir Zikria, Qais Naziri
BACKGROUND: Heterotopic ossification (HO) formation has been increasingly recognized as a complication of major orthopedic surgeries, particularly total hip arthroplasty (THA). Though, the overall incidence of HO following THA has been well-documented, it is often not reported by severity or by surgical approach. QUESTIONS/PURPOSES: (1) What are the demographics of patients with HO? (2) What is the severity of HO following THA using the Brooker classification? (3) What is the incidence and class of HO following different THA approaches (anterior, posterior, posterolateral, anterolateral, superior, lateral, trans-gluteal)? (4) What are the number and training level of surgeons who performed each procedure? METHODS: The PubMed, Embase, and Web of Science databases were queried, and PRISMA guidelines were followed...
March 27, 2024: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://read.qxmd.com/read/38536493/liraglutide-versus-pramlintide-in-protecting-against-cognitive-function-impairment-through-affecting-pi3k-akt-gsk-3%C3%AE-ttbk-pathway-and-decreasing-tau-hyperphosphorylation-in-high-fat-diet-streptozocin-rat-model
#23
JOURNAL ARTICLE
Hoda M Moghazy, Nesreen G Abdelhaliem, Sherine Ahmed Mohammed, Asmaa Hassan, Amany Abdelrahman
The American Diabetes Association guidelines (2021) confirmed the importance of raising public awareness of diabetes-induced cognitive impairment, highlighting the links between poor glycemic control and cognitive impairment. The characteristic brain lesions of cognitive dysfunction are neurofibrillary tangles (NFT) and senile plaques formed of amyloid-β deposition, glycogen synthase kinase 3 beta (GSK3β), and highly homologous kinase tau tubulin kinase 1 (TTBK1) can phosphorylate Tau proteins at different sites, overexpression of these enzymes produces extensive phosphorylation of Tau proteins making them insoluble and enhance NFT formation, which impairs cognitive functions...
March 27, 2024: Pflügers Archiv: European Journal of Physiology
https://read.qxmd.com/read/38536468/traumatic-rhabdomyolysis-rare-but-morbid-potentially-lethal-and-inconsistently-monitored
#24
JOURNAL ARTICLE
Thomas Giles, Kate King, Simone Meakes, Natasha Weaver, Zsolt J Balogh
PURPOSE: Although traumatic rhabdomyolysis (TR) is shown to be associated with acute kidney injury (AKI), there are no large prospective epidemiological studies, interventional trials, official guidelines outlining the appropriate investigation, monitoring, and treatment on this poorly understood condition. We aimed to establish the contemporary epidemiology and describe current practices for TR to power future higher quality studies. We hypothesised that investigation and monitoring occur in an ad hoc fashion...
March 27, 2024: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/38536450/surgical-management-of-chiari-ii-malformation-a-systematic-review-of-literature
#25
REVIEW
Rafael C C Vencio, Adriano M Lino-Filho, Renata C F Bonfim, Nayara M Pereira, Cilmária L Franco, Paulo Ronaldo J Ribeiro, Bárbara A Morais
PURPOSE: Chiari II malformation (CM-II) is a congenital malformation of the posterior fossa associated with myelomeningocele. Of the symptomatic patients, 10-33% require surgical treatment. To this date, there is not a consensus about the best surgical technique, and whether to do duroplasty. METHODS: A literature search of the PubMed database and crossed references was performed, per PRISMA guidelines. Data regarding demographic features, extent of cervicomedullary deformity, clinical presentation, surgical techniques, and clinical outcomes were extracted...
March 27, 2024: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://read.qxmd.com/read/38536448/arterial-spin-labelling-magnetic-resonance-imaging-and-perfusion-patterns-in-neurocognitive-and-other-mental-disorders-a-systematic-review
#26
REVIEW
Rita Ferreira, António J Bastos-Leite
We reviewed 33 original research studies assessing brain perfusion, using consensus guidelines from a "white paper" issued by the International Society for Magnetic Resonance in Medicine Perfusion Study Group and the European Cooperation in Science and Technology Action BM1103 ("Arterial Spin Labelling Initiative in Dementia"; https://www.cost.eu/actions/BM1103/ ). The studies were published between 2011 and 2023 and included participants with subjective cognitive decline plus; neurocognitive disorders, including mild cognitive impairment (MCI), Alzheimer's disease (AD), frontotemporal lobar degeneration (FTLD), dementia with Lewy bodies (DLB) and vascular cognitive impairment (VCI); as well as schizophrenia spectrum disorders, bipolar and major depressive disorders, autism spectrum disorder, attention-deficit/hyperactivity disorder, panic disorder and alcohol use disorder...
March 27, 2024: Neuroradiology
https://read.qxmd.com/read/38536412/guideline-for-sterile-technique
#27
JOURNAL ARTICLE
Lisa Croke
No abstract text is available yet for this article.
April 2024: AORN Journal
https://read.qxmd.com/read/38536407/guideline-quick-view-environment-of-care
#28
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
April 2024: AORN Journal
https://read.qxmd.com/read/38536400/guidelines-in-practice-manual-high-level-disinfection
#29
JOURNAL ARTICLE
Jennifer Speth
There are several steps involved when performing high-level disinfection (HLD) of semicritical devices. The recently updated AORN "Guideline for manual high-level disinfection" provides perioperative nurses with evidence-based best practices for performing safe and effective HLD of reusable semicritical items. The guideline also addresses preventing injury to patients and health care workers associated with the handling of high-level disinfectants. This article provides an overview of the guideline and discusses recommendations for selection of a processing method, sterile processing areas, preparation of items for HLD, preparation of high-level disinfectants, manual HLD, drying and storage of items after HLD, and processing records...
April 2024: AORN Journal
https://read.qxmd.com/read/38536223/assessment-of-patient-safety-in-a-low-resource-health-care-system-proposal-for-a-multimethod-study
#30
JOURNAL ARTICLE
Ghazal Haque, Fozia Asif, Fasih Ali Ahmed, Farwa Ayub, Sabih Ul Hassan Syed, Nousheen Akber Pradhan, Malika Hameed, Muhammad Muneeb Ullah Siddiqui, Shafaq Mahmood, Tahani Zaidi, Sameen Siddiqi, Asad Latif
BACKGROUND: The high prevalence of adverse events (AEs) globally in health care delivery has led to the establishment of many guidelines to enhance patient safety. However, patient safety is a relatively nascent concept in low- and middle-income countries (LMICs) where health systems are already overburdened and underresourced. This is why it is imperative to study the nuances of patient safety from a local perspective to advocate for the judicious use of scarce public health resources...
March 27, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38536210/association-between-adherence-to-24-hour-movement-guidelines-and-noncommunicable-disease-risk-in-chinese-adults-prospective-cohort-study
#31
JOURNAL ARTICLE
Siyi Huang, Yuxuan Gu, Shahmir H Ali, Jingjing Xue, Ronghua Zhang, Xu Wen
BACKGROUND: The increasing annual global deaths are attributable to noncommunicable chronic diseases (NCDs). Adhering to healthy lifestyle behaviors is associated with lower NCD risk, particularly among individuals with ample movement, enough sleep, and reduced sedentariness. Nevertheless, there are only few prospective assessments on the association of interactions between daily activities with NCD prevention, while the associations between adhering to Canadian 24-Hour Movement Guidelines (24HGs) for adults and NCD risks are still unknown...
March 27, 2024: JMIR Public Health and Surveillance
https://read.qxmd.com/read/38536202/venous-disorders-as-an-occupational-disease-a-systematic-review-on-epidemiology-pathophysiology-and-modification-strategies
#32
REVIEW
Tobias Hirsch, Uwe Wahl, Eberhard Rabe
<b/> Background: Forced postures are common in the workplace. Work in the primary economic sector is characterised by a high degree of physical activity and movement; however, activities in the secondary and tertiary sectors commonly require workers to stand or sit. An expansion of the tertiary sector in recent decades has meant that people in industrialised and emerging economies primarily sit or stand at work. The aim of the systematic review was to identify occupational factors relating to the presence of chronic venous disease (CVD), to place these in the context of developments in the workplace, and to determine whether measures are in place to prevent CVD...
March 27, 2024: VASA. Zeitschrift Für Gefässkrankheiten
https://read.qxmd.com/read/38536199/the-updated-college-of-american-pathologists-principles-of-analytic-validation-of-immunohistochemical-assays-a-step-forward-for-cytopathology
#33
JOURNAL ARTICLE
Sinchita Roy-Chowdhuri
No abstract text is available yet for this article.
March 27, 2024: Cancer Cytopathology
https://read.qxmd.com/read/38536167/risk-assessment-and-prevention-of-falls-in-older-community-dwelling-adults-a-review
#34
JOURNAL ARTICLE
Cathleen S Colón-Emeric, Cara L McDermott, Deborah S Lee, Sarah D Berry
IMPORTANCE: Falls are reported by more than 14 million US adults aged 65 years or older annually and can result in substantial morbidity, mortality, and health care expenditures. OBSERVATIONS: Falls result from age-related physiologic changes compounded by multiple intrinsic and extrinsic risk factors. Major modifiable risk factors among community-dwelling older adults include gait and balance disorders, orthostatic hypotension, sensory impairment, medications, and environmental hazards...
March 27, 2024: JAMA
https://read.qxmd.com/read/38536057/ankyloglossia-in-newborns-incidence-and-breastfeeding-follow-up-at-1-and-6-months
#35
JOURNAL ARTICLE
Carlo V Bellieni, Ivana LA Gioia, Irene Calcagna, Alessandra Cartocci, Lorenzo DE Stefano, Ernesto Iadanza
BACKGROUND: Ankyloglossia is an anatomical variation of the lingual frenulum that negatively interferes with the functionality of the tongue. This condition can affect breastfeeding negatively. The aim of this study is to assess the prevalence of ankyloglossia among healthy babies born in Siena Hospital and the correlation between ankyloglossia and breastfeeding difficulties. METHODS: We performed an observational prospective study conducted on healthy and breastfed newborns born in Siena Hospital in the period between January and June 2022...
March 26, 2024: Minerva pediatrics
https://read.qxmd.com/read/38535982/feasibility-of-liver-transplantation-after-90y-radioembolization-lessons-from-a-radiation-protection-incident
#36
JOURNAL ARTICLE
Marine Soret, Jacques-Antoine Maisonobe, Philippe Maksud, Stéphane Payen, Manon Allaire, Eric Savier, Charles Roux, Charlotte Lussey-Lepoutre, Aurélie Kas
Radioembolization using 90Y is a growing procedure in nuclear medicine for treating hepatocellular carcinoma. Current guidelines suggest postponing liver transplantation or surgical resection for a period of 14 to 30 d after radioembolization to minimize surgeons' exposure to ionizing radiation. In light of a radiation protection incident, we reevaluated the minimum delay required between radioembolization and subsequent liver transplantation. A patient with a hepatocellular carcinoma underwent a liver transplantation 44 h after undergoing radioembolization using 90Y (860 MBq SIR-Spheres)...
March 27, 2024: Health Physics
https://read.qxmd.com/read/38535960/indoor-air-quality-and-bioaerosols-in-spanish-university-classrooms
#37
JOURNAL ARTICLE
Esther Fuentes-Ferragud, Antonio López, Juan Miguel Piera, Vicent Yusà, Salvador Garrigues, Miguel de la Guardia, F Xavier López Labrador, Marisa Camaró, María Ibáñez, Clara Coscollà
A comprehensive study assessed indoor air quality parameters, focusing on relevant air pollutants such as particulate matter (PM10 and PM2.5 ), gaseous compounds (CO, CO2 , formaldehyde, NO2 ) and volatile/semi-volatile organic chemicals, as well as respiratory viruses (including SARS-CoV-2), fungi and bacteria in Spanish university classrooms. Non-target screening strategies evaluated the presence of organic pollutants inside and outside the classrooms. Saliva samples from teachers and students were collected to explore correlations between respiratory viruses in the air and biological samples...
March 20, 2024: Toxics
https://read.qxmd.com/read/38535916/advancing-endocrine-disruptors-via-in-vitro-evaluation-recognizing-the-significance-of-the-organization-for-economic-co-operation-and-development-and-united-states-environmental-protection-agency-guidelines-embracing-new-assessment-methods-and-the-urgent-need
#38
REVIEW
Sophie Fouyet, Marie-Caroline Ferger, Pascale Leproux, Patrice Rat, Mélody Dutot
Efforts are being made globally to improve the evaluation and understanding of endocrine-disrupting chemicals. Recognition of their impact on human health and the environment has stimulated attention and research in this field. Various stakeholders, including scientists, regulatory agencies, policymakers, and industry representatives, are collaborating to develop robust methodologies and guidelines for assessing these disruptors. A key aspect of these efforts is the development of standardized testing protocols and guidelines that aim to provide consistent and reliable methods for identifying and characterizing endocrine disruptors...
February 28, 2024: Toxics
https://read.qxmd.com/read/38535899/ecological-status-of-algeciras-bay-in-a-highly-anthropised-area-in-south-west-europe-through-metal-assessment-part-ii-biotic-samples
#39
JOURNAL ARTICLE
María José Casanueva-Marenco, María Dolores Galindo-Riaño, María Dolores Granado-Castro, Margarita Díaz-de-Alba
Biotic samples from Algeciras Bay (South-west Europe) were studied to assess its ecological status, complementing the previous abiotic monitoring of trace metals in water and sediments. This bay is a densely populated area with intense port traffic and is highly industrialised with metal inputs. To study the impact of this, Zn, Cd, Pb, and Cu contents were determined in tissues of benthic ( Solea senegalensis ) and benthopelagic species ( Scorpaena porcus , Trigloporus lastoviza, and Diplodus sargus sargus )...
February 21, 2024: Toxics
https://read.qxmd.com/read/38535873/transitional-dynamics-in-oncology-clinical-trials-evaluating-the-impact-of-clinical-trials-act-on-cooperative-groups
#40
JOURNAL ARTICLE
Kenichi Nakamura, Koji Takeda, Akiko M Saito, Miho Kato, Shinya Sato, Satoshi Nakagawa, Yasuyuki Kawamoto, Eiji Oki, Isamu Okamoto, Hiroaki Okamoto, Hiroshi Katayama, Junki Mizusawa, Harumi Kaba, Taro Shibata, Haruhiko Fukuda
OBJECTIVE: large-scale multicentre clinical trials conducted by cooperative groups have generated a lot of evidence to establish better standard treatments. The Clinical Trials Act was enforced on 1 April 2018, in Japan, and it has remarkably increased the operational burden on investigators, but its long-term impact on cancer cooperative groups is unknown. METHODS: a survey was conducted across the nine major cooperative groups that constitute the Japan Cancer Trials Network to assess the impact of Clinical Trials Act on the number of newly initiated trials from fiscal year (from 1 April to 31 March) 2017 to 2022 and that of ongoing trials on 1 April in each year from 2018 to 2023...
March 26, 2024: Japanese Journal of Clinical Oncology
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