(no author information available yet)
No abstract text is available yet for this article.
2013: Kidney International Supplements
(no author information available yet)
No abstract text is available yet for this article.
2013: Kidney International Supplements
Gamze Akkus, Barış Karagun, Hilal Nur Yaldız, Mehtap Evran, Murat Sert, Tamer Tetiker
OBJECTIVES: Prolactinoma is the most common cause of pituitary tumours. Current medical guidelines recommend dopamine agonists (cabergoline or bromocriptine) as the initial therapy for prolactinoma. However, surgical removal can also be considered in selected cases, such as patients with macroadenomas with local complications (bleeding or optic chiasm pressure) or those not responding to medical treatment. METHODS: The present retrospective study included patients with prolactinomas (n=43; female, 24; male, 19) who were primarily managed with medical (n=32) or surgical (n=11) treatment...
December 17, 2020: Hormone Molecular Biology and Clinical Investigation
Mateus Henrique Petrarca, Patrícia Aparecida de Campos Braga, Felix Guillermo Reyes Reyes, Adriana Pavesi Arisseto Bragotto
Miniaturized and simplified sample preparation methods with reduced consumption of chemicals and non-halogenated solvents are presented for the determination of 12 sulfonamides in baby foods. Hydrophilic interaction liquid chromatography coupled to quadrupole time-of-flight mass spectrometry was used for the identification and quantification of the compounds based on the acquisition of full spectrum at high resolution with accurate mass for precursor and its fragment ions. Three miniaturized protocols based on QuEChERS, salting-out assisted liquid-liquid extraction or low-temperature cleanup were evaluated regarding the extraction efficiency and removal capability of matrix co-extractives...
July 14, 2021: Food Chemistry
Haroon Elrasheid Tahir, Muhammad Arslan, Gustav Komla Mahunu, Abdalbasit Adam Mariod, Sulafa B H Hashim, Zou Xiaobo, Shi Jiyong, Hesham R El-Seedi, Taha H Musa
The global market for imported, high-quality priced foods has grown dramatically in the last decade, as consumers become more conscious of food originating from around the world. Many countries require the origin label of food to protect consumers need about true characteristics and origin. Regulatory authorities are looking for an extended and updated list of the analytical techniques for verification of authentic oils and to support law implementation. This review aims to introduce the efforts made using various analytical tools in combination with the multivariate analysis for the verification of the geographical origin of oils...
July 20, 2021: Food Chemistry
Benqin Yang, Die Hu, Yanmei Liu, Zhiqiang Lin, Xiandong Zhou, Qian Pan, Hongxu Zhu, Xuejun Pan
More food waste (FW) is desired to be treated in a certain processing period, while the degradation pattern of biochemical fractions during FW bioevaporation was significantly influenced by the organic loading (OL). Lower OL facilitated the lipids degradation, while higher OL favored the protein degradation. It was the more porous structure and abundant oxygen accelerated the lipids degradation, and the rapid proliferation of aerobic microorganisms compensated for the low protein degradation in lower OL. Detailly, 76...
July 28, 2021: Waste Management
Zhenwei Zhong, Yue Yang, Xiaorui Chen, Zhen Han, Jincai Zhou, Bohua Li, Xiaowen He
In the past, specificity and affinity were the priority for synthetic antibody library. However, therapeutic antibodies need good stability for medical use. Through carefully adjust the chemical diversity in CDRs, one hopes to design a synthetic antibody library with good developability. Here we thoroughly analyzed 296 nanobody sequences and structures, constructed a fully-functional synthetic nanobody library, evaluated the relationship between aggregation and isoelectric point, and found that high-pI nanobodies were more resistant to aggregation than low-pIs...
July 28, 2021: Biochemical and Biophysical Research Communications
José Francisco López-Gil, Anelise R Gaya, Cézane P Reuter, Cristiano Israel Caetano, Rafael Gomes Sentone, Hallyne Bergamini Silva Caetano, Javier Brazo-Sayavera
The pandemic has affected children's behaviors and this fact has an effect on their healthy habits, such as sleep and diet. The aim of the current study was to determinate the prevalence of sleep-related problems and its relationship with eating habits in children from the south of Brazil during the pandemic. Parents/legal guardians of 3-17 years old participants responded to a online survey distributed using the snowball sampling strategy in Brazil. The survey was conducted in April, 2020. Participants were asked for their sleep duration and sleep-related problems, as well as for their eating habits...
July 7, 2021: Sleep Medicine
Diletta Biagi, Paolo Nencioni, Maurizio Valleri, Niccolò Calamassi, Paola Mura
The Food and Drug Administration (FDA)'s guidelines and the Process Analytical Technology (PAT) approach conceptualize the idea of real time monitoring of a process, with the primary objective of improvement of quality and also of time and resources saving. New instruments are needed to perform an efficient PAT process control and Near Infrared Spectroscopy (NIRS), thanks to its rapid and drastic development of last years, could be a very good choice, in virtue of its high versatility, speed of analysis, non-destructiveness and absence of sample chemical treatment...
July 22, 2021: Journal of Pharmaceutical and Biomedical Analysis
Fabian Leo, Marwin Bannehr, Swantje Valenta, Madlen Lippeck, Sebastian Pachl, Michaela Steib-Bauert, Hannes Semper, Christian Grohé
BACKGROUND: In hospitalized patients, the duration of antibiotic therapy for uncomplicated pneumonia is often longer than recommended in clinical guidelines. Consequences include increased risk of Clostridioides difficile infection and the emergence of antibiotic resistance. Reducing the duration of antibiotic therapy is an important goal of antibiotic stewardship (ABS) programs. OBJECTIVE: To evaluate the impact of a computerized physician order entry (CPOE)-based ABS intervention on treatment duration in respiratory infections and on antibiotic use...
July 24, 2021: Respiratory Medicine
Caitlin A Howlett, Michael A Wewege, Carolyn Berryman, Annika Oldach, Elizabeth Jennings, Emily Moore, Emma L Karran, Kimberley Szeto, Leander Pronk, Stephanie Miles, G Lorimer Moseley
Cognitive flexibility can be thought of as the ability to effectively adapt one's cognitive and behavioural strategies in response to changing task or environmental demands. To substantiate the common inference that self-report and neuropsychological tests of cognitive flexibility provide 'different windows into the same room', we undertook a systematic review and meta-analysis to determine whether self-report and neuropsychological tests of cognitive flexibility are related in healthy adults. Ten databases and relevant grey literature were searched from inception...
June 26, 2021: Clinical Psychology Review
Pierre Nahon, Christophe Aubé, Lucile Moga, Julia Chalaye, Boris Guiu, Alain Luciani, Agnès Rode, Maxime Ronot, Olivier Seror, Michael Soussan, Olivier Sutter, Marc Bourlière, Christophe Bureau, Victor de Lédinghen, Nathalie Ganne-Carrié
Among a wide range of malignant liver tumours, hepatocellular carcinoma (HCC) developed on a background of cirrhosis represents the most frequent clinical situation. In this setting, HCC is one of the rare solid tumours for which histological confirmation is not mandatory. The convergence of multiple arguments obtained by non-invasive parameters using radiological findings allows to avoid liver biopsy in a large proportion of patients when a diagnosis of underlying cirrhosis is ascertained. Conversely, in case of atypical presentation or in order to exclude other rare malignant tumours mostly developed in the absence of cirrhosis, liver biopsy will then be essential...
July 28, 2021: Clinics and Research in Hepatology and Gastroenterology
Albert Tran, Sarah Shili-Masmoudi, Lucile Moga, Stéphane Chevaliez, Alain Luciani, Isaac Ruiz, Nathalie Ganne-Carrié, Christophe Bureau, Marc Bourlière, Victor de Lédinghen
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease. Clinical care for patients with HCV-related liver disease has advanced considerably with developments in screening, diagnostic procedures to evaluate liver fibrosis and improvements in therapy with pangenotypic direct antivirals and prevention. These AFEF guidelines on the non-invasive diagnosis and follow up of chronic infection with HCV describe the optimal management of HCV positive patients with non-invasive methods in screening, in assessing viral disease and liver fibrosis and the follow-up of these patients according to the value of FibroScan®, Fibrotest® or Fibrometer®...
July 28, 2021: Clinics and Research in Hepatology and Gastroenterology
Sara Lemoinne, Alexandra Heurgue, Charlotte Bouzbib, Bertrand Hanslik, Jérôme Gournay, Eric Nguyen-Khac, Christophe Bureau, Victor de Lédinghen, Nathalie Ganne-Carrié, Marc Bourlière
Autoimmune hepatitis (AIH) is a liver disease characterised by necrotico-inflammatory lesions of hepatocytes, the presence of specific autoantibodies and response to corticosteroid treatment. AIH must be considered in any patient with acute or chronic liver disease. As there is no pathognomonic sign of AIH, the diagnosis is based on a combination of clinical, biological, immunological and histological findings, after excluding other causes of liver disease. The clinical and biological presentation of AIH is variable and AIH can be associated with an autoimmune biliary disease, primary biliary cholangitis or primary sclerosing cholangitis in an overlap syndrome...
July 28, 2021: Clinics and Research in Hepatology and Gastroenterology
Daniel J Cognetti, Jonathan D Hughes, Jeffrey Kay, Jesse Chasteen, Michael A Fox, Robert U Hartzler, Albert Lin, Andrew J Sheean
PURPOSE: To determine if posterior glenoid bone block augmentation performed for the treatment of recurrent posterior shoulder instability succeeds in restoring stability and is associated with rates of complications and/or clinical failures comparable to other glenoid bone augmentation procedures. METHODS: A comprehensive search of the PubMed, MEDLINE, and EMBASE databases was performed. Level of evidence studies I-IV pertaining to posterior bone block augmentation reporting on outcomes and/or complications were included...
July 28, 2021: Arthroscopy
Narayanan Namboodiri, Kartikeya Bhargava, Deepak Padmanabhan, Raja Selvaraj, Ulhas Pandurangi, Vanita Arora, Vivek Chaturvedi, Ashish Nabar, Ameya Udyavar, R D Yadave, Yash Lokhandwala
No abstract text is available yet for this article.
July 28, 2021: Indian Pacing and Electrophysiology Journal
Graham Nichol, Mohamud R Daya, Laurie J Morrison, Tom P Aufderheide, Christian Vaillancourt, Gary M Vilke, Ahamed Idris, Siobhan Brown
BACKGROUND: Analyses of data recorded by monitor-defibrillators that measure CPR depth with different methods show significant relationships between the process and outcome of CPR. Our objective was to evaluate whether chest compression depth was significantly associated with outcome based on accelerometer-recordings obtained with monitor-defibrillators from a single manufacturer, and to assess whether an accelerometer-based analysis corroborated evidence-based practice guidelines on performance of CPR...
July 28, 2021: Resuscitation
Phoebe Simpson, Riikka Holopainen, Robert Schütze, Peter O'Sullivan, Anne Smith, Steven J Linton, Michael Nicholas, Peter Kent
OBJECTIVE: Current guidelines recommend management of musculoskeletal pain conditions from a biopsychosocial approach, however biopsychosocial interventions delivered by physical therapists vary considerably in effectiveness. It is unknown whether the differences are explained by the intervention itself, the training and/or competency of physical therapists delivering the intervention, or fidelity of the intervention. The aim was to investigate and map the training, competency assessments and fidelity checking of individualized biopsychosocial interventions delivered by physical therapists to treat musculoskeletal pain conditions...
July 30, 2021: Physical Therapy
Kamil Jurowski, Maria Fołta, Barbara Tatar, Mehmet Berkoz, Mirosław Krośniak
Essential elements like Cu, Mn and Zn are extremely important for herbs' growth and physiological functions; however, from a toxicological point of view, the exposure of these elements (as essential elemental impurities) can exhibit potential harmful effects for patients. In Europe, very popular are ointments with Marjoram herb extract (Majoranae herbae extractum) as herbal medicinal products for adjunctively in rhinitis (runny nose). Based on posology of ointments with Marjoram herb extract, the exposure to these elemental impurities may be high during long-term use...
July 31, 2021: Biological Trace Element Research
Nara Jesus Brito, Vívian Volkmer Pontes, Vania Bustamante
From 2015 to 2016, an epidemic of births of children with Congenital Zika Virus Syndrome emerged in Brazil, and the state of Bahia concentrated the highest incidence of cases. The official health guidelines recommended that the affected children and their families should be supported by interdisciplinary teams of early intervention. This paper aims to deepen the comprehension of regulation and affective-semiotic mediation processes involved in the early intervention with children with Congenital Zika Virus Syndrome and their families...
July 31, 2021: Integrative Psychological & Behavioral Science
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