Anke Tropitzsch, Thore Schade-Mann, Philipp Gamerdinger, Saskia Dofek, Björn Schulte, Martin Schulze, Sarah Fehr, Saskia Biskup, Tobias B Haack, Petra Stöbe, Andreas Heyd, Jennifer Harre, Anke Lesinski-Schiedat, Andreas Büchner, Thomas Lenarz, Athanasia Warnecke, Marcus Müller, Barbara Vona, Ernst Dahlhoff, Hubert Löwenheim, Martin Holderried
OBJECTIVES: The variability in outcomes of cochlear implantation is largely unexplained, and clinical factors are not sufficient for predicting performance. Genetic factors have been suggested to impact outcomes, but the clinical and genetic heterogeneity of hereditary hearing loss makes it difficult to determine and interpret postoperative performance. It is hypothesized that genetic mutations that affect the neuronal components of the cochlea and auditory pathway, targeted by the cochlear implant (CI), may lead to poor performance...
July 13, 2023: Ear and Hearing