Anatoly V Skalny, Michael Aschner, Aristidis Tsatsakis, Joao B T Rocha, Abel Santamaria, Demetrios A Spandidos, Airton C Martins, Rongzhu Lu, Tatiana V Korobeinikova, Wen Chen, Jung-Su Chang, Jane C J Chao, Chong Li, Alexey A Tinkov
The objective of the present review was to summarize the molecular mechanisms associated with the effects of the vitamins A, C, E and K, and group B vitamins on bone and their potential roles in the development of osteoporosis. Epidemiological findings have demonstrated an association between vitamin deficiency and a higher risk of developing osteoporosis; vitamins are positively related to bone health upon their intake at the physiological range. Excessive vitamin intake can also adversely affect bone formation, as clearly demonstrated for vitamin A...
January 2024: International Journal of Molecular Medicine