L E Durán-Carabali, F K Odorcky, L K Grun, F Schmitz, O V Ramires Junior, M R de Oliveria, K F Campos, E Hoeper, A V S Carvalho, S Greggio, G T Venturine, E R Zimmer, F Barbé-Tuana, A T S Wyse, C A Netto
There is evidence that maternal milieu and changes in environmental factors during the prenatal period may exert a lasting impact on the brain health of the newborn, even in case of neonatal brain hypoxia-ischemia (HI). The present study aimed to investigate the effects of maternal environmental enrichment (EE) on HI-induced energetic and metabolic failure, along with subsequent neural cell responses in the early postnatal period. Male Wistar pups born to dams exposed to maternal EE or standard conditions (SC) were randomly divided into Sham-SC, HI-SC, Sham-EE, and HI-EE groups...
February 5, 2024: Experimental Neurology