Naoto Kuroda, Kiril Trpkov, Yuan Gao, Maria Tretiakova, Yajuan J Liu, Monika Ulamec, Kengo Takeuchi, Abbas Agaimy, Christopher Przybycin, Cristina Magi-Galluzzi, Soichiro Fushimi, Fumiyoshi Kojima, Malthide Sibony, Jen-Fan Hang, Chin-Chen Pan, Asli Yilmaz, Farshid Siadat, Emiko Sugawara, Pierre-Alexandre Just, Nikola Ptakova, Ondrej Hes
ALK rearranged renal cell carcinoma (ALK-RCC) has recently been included in 2016 WHO classification as a provisional entity. In this study, we describe 12 ALK-RCCs from 8 institutions, with detailed clinical, pathological, immunohistochemical (IHC), fluorescence in situ hybridization (FISH), and next generation sequencing (NGS) analyses. Patients' age ranged from 25 to 68 years (mean, 46.3 years). Seven patients were females and five were males (M:F = 1:1.4). Tumor size ranged from 17 to 70 mm (mean 31...
December 2020: Modern Pathology