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diabetes depression randomized

L J van der Donk, J Fleer, R Sanderman, P M G Emmelkamp, T P Links, K A Tovote, M J Schroevers
AIMS: The objective of this study is to investigate whether type of depressive symptoms (i.e. cognitive-affective or somatic) is related to a patient-perceived need for professional psychological care in individuals with diabetes. METHODS: In total 2266 participants were recruited as part of the screening procedure for a multi-center randomized controlled trial on the treatment of depressive symptoms among individuals with diabetes. Individuals were invited to complete Beck Depression Inventory-II (BDI-II)...
2019: PloS One
Wen-Wen Cheng, Qiang Zhu, Hong-Yu Zhang
We applied Mendelian randomization analyses to investigate the potential causality between blood minerals (calcium, magnesium, iron, copper, and zinc) and osteoporosis (OP), gout, rheumatoid arthritis (RA), type 2 diabetes (T2D), Alzheimer's disease (AD), bipolar disorder (BD), schizophrenia , Parkinson's disease and major depressive disorder. Single nucleotide polymorphisms (SNPs) that are independent ( r ² < 0.01) and are strongly related to minerals ( p < 5 × 10-8 ) are selected as instrumental variables...
February 12, 2019: Nutrients
Alicia Monreal-Bartolomé, Alberto Barceló-Soler, Adoración Castro, Mª Ángeles Pérez-Ara, Margalida Gili, Fermín Mayoral, Maria Magdalena Hurtado, Esperanza Varela Moreno, Cristina Botella, Azucena García-Palacios, Rosa M Baños, Yolanda López-Del-Hoyo, Javier García-Campayo
BACKGROUND: The World Health Organization (WHO) has included comorbidity between depression and a chronic disease among the 10 leading global health priorities. Although there is a high prevalence of multimorbidity, health care systems are mainly designed for the management of individual diseases. Given the difficulty in delivering face-to-face psychological treatments, alternative models of treatment delivery have been proposed, emphasizing the role of technologies such as the Internet...
February 11, 2019: BMC Psychiatry
Milad Azami, Gholamreza Badfar, Ali Solemani, Shoboo Rahmati
AIMS: Postpartum period is a critical period for mothers, which is often accompanied by increased risk of depression. Many studies have evaluated the relationship between gestational diabetes (GDM) and postpartum depression (PPD), but contradictory results have been reported. Therefore, the present study was conducted to investigate the relationship between gestational diabetes and Postpartum Depression. METHODS: This systematic review and meta-analysis was conducted based on PRISMA Guideline...
February 5, 2019: Diabetes Research and Clinical Practice
Natalia Stanulewicz, Peter Mansell, Debbie Cooke, David Hopkins, Jane Speight, Holly Blake
OBJECTIVE: The Problem Areas In Diabetes (PAID) questionnaire is widely used to assess emotional distress related to living with diabetes, although it is lengthy for routine clinical use. Our aim was to determine whether the original 20-item PAID questionnaire can be abbreviated, whilst maintaining its reliability, validity and utility. METHODS: We analysed data from the UK DAFNE (Dose Adjustment For Normal Eating) education programme for adults with Type 1 diabetes...
January 30, 2019: Diabetes Research and Clinical Practice
Qiuxia Pan, Jiajia Wu, Yueyun Liu, Xiaojuan Li, Jiaxu Chen
BACKGROUND: Long-term exposure to chronic stress is thought to be a factor closely correlated with the development of metabolic disorders, such as diabetes mellitus and metabolic syndrome. Xiaoyaosan, a Chinese herbal formula, has been described in many previous studies to exert anxiolytic-like or antidepressant effects in chronically stressed rats. However, few studies have observed the effects of Xiaoyaosan on the metabolic disorders induced by chronic stress. OBJECTIVE: We sought to investigate the effective regulation of Xiaoyaosan on 21-day chronic immobility stress (CIS, which is 3 h of restraint immobilization every day)-induced behavioural performance and metabolic responses and to further explore whether the effects of Xiaoyaosan were related to SHIP2 expression in the liver...
January 29, 2019: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Archana Sarda, Suresh Munuswamy, Shubhankar Sarda, Vinod Subramanian
BACKGROUND: Research studies are establishing the use of smartphone sensing to measure mental well-being. Smartphone sensor information captures behavioral patterns, and its analysis helps reveal well-being changes. Depression in diabetes goes highly underdiagnosed and underreported. The comorbidity has been associated with increased mortality and worse clinical outcomes, including poor glycemic control and self-management. Clinical-only intervention has been found to have a very modest effect on diabetes management among people with depression...
January 29, 2019: JMIR MHealth and UHealth
Lisa B Cohen, Tracey H Taveira, Wen-Chih Wu, Paul A Pirraglia
INTRODUCTION: The aim of this study was to determine whether a pharmacist-led telehealth disease management program is superior to usual care of nurse-led telehealth in improving diabetes medication adherence, haemoglobin A1C (A1C), and depression scores in patients with concomitant diabetes and depression. METHODS: Patients with diabetes and depression were randomized to pharmacist-led or nurse-led telehealth. Veterans with type 1 or type 2 diabetes, an A1C ≥ 7...
January 28, 2019: Journal of Telemedicine and Telecare
Benjamin M Bluml, Leslie E Kolb, Ruth Lipman
This was a randomized controlled study to test a scalable intervention model addressing the need for ongoing diabetes support. The study included individuals receiving care in a Federally Qualified Health Center (FQHC) with HbA1c >8. The aim of this project was to determine whether augmenting diabetes self-management education (DSME) with support for an economically vulnerable population might better meet patient needs and reduce morbidity and premature mortality. The intervention utilized pre and post comparisons and was designed to test the efficacy of a telephonic diabetes support intervention to increase patient engagement in self-care and with the health care system as a means to improve clinical outcomes...
January 22, 2019: Population Health Management
Muhammad Atif, Quratulain Saleem, Saima Asghar, Iram Malik, Nafees Ahmad
Objectives: This study aimed to explore the relationship between glycaemic control and factors that may influence this among elderly type 2 diabetes mellitus (T2DM) patients in Lahore, Pakistan. Methods: This descriptive, cross-sectional study was conducted at the Jinnah and Sir Ganga Ram Hospitals, Lahore using convenience sampling techniques between 1 December 2015 and 28 February 2016. The sample consisted of elderly (>65 years) T2DM patients. Glycaemic values and patient characteristics were obtained from medical charts...
January 17, 2019: Medicina
Cauê Pontes Briganti, Marcus Tolentino Silva, José Vanilton de Almeida, Cristiane de Cássia Bergamaschi
OBJECTIVE: To determine the prevalence of current depressive symptoms in people with diabetes mellitus and their association with the disease. METHODS: Data were collected from the Brazilian National Health Survey (Pesquisa Nacional de Saúde - PNS), a cross-sectional, population-based study conducted in 2013. Study participants were selected by simple random cluster sampling in three stages: census tracts, households, and residents aged ≥ 18 years. The presence of diabetes was self-reported, whereas the presence of current depressive symptoms was determined by the Patient Health Questionnaire-9 (PHQ-9) and mean scores of this questionnaire were calculated for the variables assessed...
December 20, 2018: Revista de Saúde Pública
Ana Garcia-Arellano, Miguel A Martínez-González, Raul Ramallal, Jordi Salas-Salvadó, James R Hébert, Dolores Corella, Nitin Shivappa, Luis Forga, Helmut Schröder, Carlos Muñoz-Bravo, Ramón Estruch, Miquel Fiol, José Lapetra, Lluís Serra-Majem, Emilio Ros, Javier Rekondo, Estefanía Toledo, Cristina Razquin, Miguel Ruiz-Canela
BACKGROUND: Inflammation is known to be related to the leading causes of death including cardiovascular disease, several types of cancer, obesity, type 2 diabetes, depression-suicide and other chronic diseases. In the context of whole dietary patterns, the Dietary Inflammatory Index (DII® ) was developed to appraise the inflammatory potential of the diet. OBJECTIVE: We prospectively assessed the association between DII scores and all-cause mortality in two large Spanish cohorts and valuated the consistency of findings across these two cohorts and results published based on other cohorts...
May 24, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
Simone Brefka, Dhayana Dallmeier, Viktoria Mühlbauer, Christine A F von Arnim, Claudia Bollig, Graziano Onder, Mirko Petrovic, Carlos Schönfeldt-Lecuona, Moritz Seibert, Gabriel Torbahn, Sebastian Voigt-Radloff, Walter E Haefeli, Jürgen M Bauer, Michael D Denkinger
When treating older adults, a main factor to consider is physical frailty. Because specific assessments in clinical trials are frequently lacking, critical appraisal of treatment evidence with respect to functional status is challenging. Our aim was to identify and categorize assessments for functional status given in clinical trials in older adults to allow for a retrospective characterization and indirect comparison of treatment evidence from these cohorts. We conducted 4 separate systematic reviews of randomized and nonrandomized controlled clinical trials in older people with hypertension, diabetes, depression, and dementia...
January 9, 2019: Journal of the American Medical Directors Association
Jacqueline Hallanzy, Martina Kron, Veronika E Goethe, Frank-Michael Köhn, Maximilian Schmautz, Christian Arsov, Boris Hadaschik, Florian Imkamp, Jürgen E Gschwend, Kathleen Herkommer
BACKGROUND: Erectile dysfunction (ED) is a common public health issue with a significant impact on quality of life. The associations between ED and several risk factors have been reported previously. The continuously increasing incidence of these factors is contributing to the increasing prevalence of ED. AIM: To assess ED prevalence and severity in a representative sample of 45-year-old German men and to analyze the association with risk factors (lifestyle risk factors/comorbidities)...
January 9, 2019: Sexual Medicine
Yanan Luo, Dawei Zhu, Stephen Nicholas, Ping He
OBJECTIVE: While diabetes links with comorbidity of depression, there is no evidence in China regarding whether health behaviors modified the effect of depressive symptoms on diabetes. This study examined the influence of depressive symptoms on the incident diabetes, and investigated whether health behavior was a moderator in the depression-diabetes relationship in Chinese mid-aged and older adults. METHODS: Using data from the China Health and Retirement Longitudinal 2011-2015 Study, the 10-item Center for Epidemiologic Studies Depression Scale (CESD-10) short form was used to measure depressive symptoms in 47,671 Chinese mid-aged and older adults...
December 27, 2018: Journal of Affective Disorders
Anne Sophie Mathiesen, Ingrid Egerod, Tonny Jensen, Gudrun Kaldan, Henning Langberg, Thordis Thomsen
Diabetes distress (DD) disproportionately affects vulnerable people with type 2 diabetes mellitus and interventions targeting this population are therefore relevant. A systematic review and meta-analysis was performed to assess the evidence for an effect of psychosocial interventions for reducing DD, and, secondly HbA1c, depression, and health-related quality of life in vulnerable people with type 2 diabetes mellitus. Vulnerability encompasses poor glycemic control (HbA1c >7.5%) and at least one additional risk factor for poor diabetes outcomes such as low educational level, comorbidity, and risky lifestyle behavior...
2019: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Martina Biggioggero, Chiara Crotti, Andrea Becciolini, Ennio Giulio Favalli
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by articular and systemic manifestations, such as anemia, fatigue, osteoporosis, and increased risk for cardiovascular diseases. The pathogenesis of RA is driven by a complex network of proinflammatory cytokines, with a pivotal role of IL-6 and tumor necrosis factor (TNF). The management of RA has been dramatically changed during the last years by the introduction of a treat-to-target approach aiming to achieve an acceptable disease control...
2019: Drug Design, Development and Therapy
Dorairaj Prabhakaran, Dilip Jha, David Prieto-Merino, Ambuj Roy, Kavita Singh, Vamadevan S Ajay, Devraj Jindal, Priti Gupta, Dimple Kondal, Shifalika Goenka, Pramod David Jacob, Rekha Singh, B G Prakash Kumar, Pablo Perel, Nikhil Tandon, Vikram Patel
BACKGROUND: The burden of noncommunicable diseases and their risk factors has rapidly increased worldwide, including in India. Innovative management strategies with electronic decision support and task sharing have been assessed for hypertension, diabetes mellitus, and depression individually, but an integrated package for multiple chronic condition management in primary care has not been evaluated. METHODS: In a prospective, multicenter, open-label, cluster-randomized controlled trial involving 40 community health centers, using hypertension and diabetes mellitus as entry points, we evaluated the effectiveness of mWellcare, an mHealth system consisting of electronic health record storage and an electronic decision support for the integrated management of 5 chronic conditions (hypertension, diabetes mellitus, current tobacco and alcohol use, and depression) versus enhanced usual care among patients with hypertension and diabetes mellitus in India...
November 10, 2018: Circulation
Romina Pace, Elham Rahme, Deborah Da Costa, Kaberi Dasgupta
Purpose: The aim of this study was to examine the association between gestational diabetes mellitus (GDM) and depression incidence in mothers and fathers during prenatal and postnatal periods. Patients and methods: Matched pairs (GDM vs no GDM) of randomly selected mothers with singleton live births (matched by age group, delivery year, and health region) and their partners (Quebec, Canada; cohort inception 1990-2007) were assessed for a composite outcome of depression/self-harm/suicide using a health administrative database...
2018: Clinical Epidemiology
Harald M Stauss, Hubert Stangl, Karen C Clark, Anne E Kwitek, Vitor A Lira
Previously, we reported that cervical vagal nerve stimulation (VNS) increases blood glucose levels and inhibits insulin secretion in anesthetized rats through afferent signaling. Since afferent signaling is also thought to mediate the therapeutic effects of VNS in patients with therapy-refractory epilepsy and major depression, the question arises if patients treated with VNS develop impaired glucose tolerance. Thus, we hypothesized that cervical VNS impairs glucose tolerance in conscious rats. Rats (n = 7) were instrumented with telemetric blood pressure sensors and right- or left-sided cervical vagal nerve stimulators (3 V, 5 Hz, 1 msec pulse duration, 1 h on 1 h off)...
December 2018: Physiological Reports
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