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Placental thickness

Khadijah I Ismail, Ailish Hannigan, Peter Kelehan, Brendan Fitzgerald, Keelin O'Donoghue, Amanda Cotter
INTRODUCTION: Individual placental and umbilical cord morphometry have been previously identified to have an association with fetal growth. This study aims to identify which of the morphometric measurements in combination are associated with pregnancies with small for gestational age (SGA) infants using digital imaging of the delivered placenta. MATERIAL AND METHODS: This study examined 1005 placentas from consecutively delivered singleton pregnancies in a tertiary center...
February 13, 2019: Journal of Maternal-fetal & Neonatal Medicine
Paola I Rosado-Yépez, Dora V Chávez-Corral, Sandra A Reza-López, Irene Leal-Berumen, Ricardo Fierro-Murga, Selene Caballero-Cummings, Margarita Levario-Carrillo
OBJECTIVE: To evaluate the morphology of the placenta in patients with pregestational overweight (OW), pregestational obesity (PGOB), or normal weight. METHODS: A cross-sectional study including women (n = 114) ≥20 years of age with a singleton pregnancy was carried out. The groups were integrated according to pregestational body mass index (BMI): 51 patients had a normal BMI (18.5-24.99 kg/m2 ), 30 were overweight (25-29.99 kg/m2 ), and 33 women were obese (≥30...
January 31, 2019: Journal of Maternal-fetal & Neonatal Medicine
Tetsuya Kawakita, Sara N Iqbal, Helain J Landy, Jim C Huang, Melissa Fries
OBJECTIVE: To examine the association of a resident-driven quality initiative with cesarean delivery surgical site infections. METHODS: This was a quasi-experimental, preintervention and postintervention study of women undergoing cesarean delivery at 23 weeks of gestation or greater between January 2015 and June 2018 at a single tertiary care center. We implemented a resident-driven, evidence-based surgical bundle, excluding women who underwent emergency cesarean or had chorioamnionitis...
January 8, 2019: Obstetrics and Gynecology
Rupali Mahajan, Paramjit Khinda, Akhilesh Shewale, Komaldeep Ghotra, Meenu Taneja Bhasin, Prashant Bhasin
Background: Guided tissue regeneration-based root coverage has emerged as a promising treatment modality in the treatment of gingival recession. A variety of nonresorbable and bioresorbable membranes have been successfully used. Among resorbable membranes, collagen has been extensively studied. Recently, a third generation barrier membrane derived from placenta has been introduced for periodontal regeneration. Aim: The objective of the present study is to clinically compare the efficacy of placental membrane (Amnion) and collagen membrane (Healiguide) for the treatment of gingival recession...
November 2018: Journal of Indian Society of Periodontology
M-J Allard, M-E Brochu, J D Bergeron, M Segura, G Sébire
Chorioamnionitis and intrauterine growth retardation (IUGR) are risk factors for cerebral palsy (CP). Common bacteria isolated in chorioamnionitis include group B Streptococcus (GBS) serotypes Ia and III. Little is known about the impact of placental inflammation induced by different bacteria, including different GBS strains. We aimed to test the impact of chorioamnionitis induced by two common GBS serotypes (GBSIa and GBSIII) on growth and neuromotor outcomes in the progeny. Dams were exposed at the end of gestation to either saline, inactivated GBSIa or GBSIII...
January 10, 2019: Journal of Developmental Origins of Health and Disease
Dinakar Golla, Dorothy H Kurtz Phelan
INTRODUCTION: Surgical closure of late-stage pressure ulcers (PUs) poses challenges in the immobilized population due to the high rate of complications, including infection, dehiscence, and recurrence. Muscle flap closure is the standard treatment for chronic, late-stage (stage 4) PUs, characterized by the European Pressure Ulcer Advisory Panel and National Pressure Ulcer Advisory Panel as full-thickness tissue loss with exposure of bone, tendon, or muscle. OBJECTIVE: The aim of this study is to evaluate the outcomes associated with the use of a cryopreserved placental membrane containing viable cells (vCPM) graft for the augmentation of surgical flap closure in nonhealing perineal ulcers...
January 2019: Wounds: a Compendium of Clinical Research and Practice
Natalie M Warburton, Philip W Bateman, Patricia A Fleming
The mammalian penis is a complex hydraulic organ of cavernous (spongy) tissue supported by both smooth and skeletal muscle structures. In placental mammals, the paired ‎Musculus ischiocavernosi anchor the corpora cavernosa to the pelvis (at the ischium), and the paired M. bulbospongiosi converge as they envelop the base of the corpus spongiosum. Male marsupials have a dramatically different anatomy, however, in which both sets of paired muscles remain separate, have a bulbous, globular shape and do not have any direct connection to the pelvis...
January 6, 2019: Journal of Anatomy
Nobuhiro Terao, Hideki Koizumi, Kentaro Kojima, Tetsuya Yamagishi, Kenji Nagata, Koji Kitazawa, Yuji Yamamoto, Kengo Yoshii, Asako Hiraga, Munetoyo Toda, Shigeru Kinoshita, Chie Sotozono, Junji Hamuro
Purpose: To clarify the distinct molecular pathogenesis of central serous chorioretinopathy (CSC) and pachychoroid neovasculopathy (PNV). Methods: Aqueous humor (AH) was collected from 18 acute CSC, 20 chronic CSC, and 20 PNV patients. Concentrations of 30 cytokines in the AH were analyzed using a multiplex bead immunoassay, and the cytokine profiles were compared among these three groups of patients. The areas of choroidal vascular hyperpermeability (CVH) and choroidal thickness (CT), including measurement of the vascular layers, were investigated to analyze the features of choroidal abnormality in acute CSC, chronic CSC, and PNV...
December 3, 2018: Investigative Ophthalmology & Visual Science
Tiziana Nervo, Alessia Bertero, Mariagrazia Poletto, Paola Pregel, Roberta Leone, Valentina Toffoli, Leila Vincenti
The aim of this study was to collect and analyze ultrasound measurements of fetal-maternal structures during normal and pathological pregnancies in jennies, a livestock species of growing interest. For two breeding seasons, 38 jennies of different breeds and crossbreeds aged between 3 and 18 years were monitored weekly by transrectal examination using a portable Esaote ultrasound (MyLab™ 30 GOLD VET) with a 5-7.5 MHz probe. The jennies were divided into two groups, < 250 kg and >250 kg body weight, and the dates of conception and parturition/abortion were recorded to calculate pregnancy length...
November 22, 2018: Theriogenology
Ryosuke Motohashi, Hidetaka Noma, Kanako Yasuda, Osamu Kotake, Hiroshi Goto, Masahiko Shimura
Background: Intravitreal ranibizumab injection (IRI) is effective for patients with exudative age-related macular degeneration (AMD) and decreases intraocular levels of vascular endothelial growth factor (VEGF), but VEGF receptor intraocular dynamics after IRI are unclear. Therefore, we evaluated changes in the aqueous humor levels of soluble vascular endothelial growth factor receptor (sVEGFR)-1, sVEGFR-2, and their ligands for these receptors (VEGF) patients with AMD receiving IRI. Methods: The subjects were 24 patients with AMD (24 eyes) who received 3 doses of IRI at monthly intervals...
2018: Journal of Inflammation
Shayesteh Khalifeh Soltani, Bijan Forogh, Naser Ahmadbeigi, Homayoun Hadizadeh Kharazi, Khadijeh Fallahzadeh, Ladan Kashani, Masoumeh Karami, Yadollah Kheyrollah, Mohammad Vasei
OBJECTIVE: Knee osteoarthritis (OA) is a common skeletal impairment that can cause many limitations in normal life activities. Stem cell therapy has been studied for decades for its regenerative potency in various diseases. We investigated the safety and efficacy of intra-articular injection of placental mesenchymal stem cells (MSCs) in knee OA healing. METHODS: In this double-blind, placebo-controlled clinical trial, 20 patients with symptomatic knee OA were randomly divided into two groups to receive intra-articular injection of either 0...
December 3, 2018: Cytotherapy
Yuri K Sinzato, Estela M Bevilacqua, Gustavo T Volpato, Rogelio E Hernandez-Pando, Marilza V C Rudge, Débora Cristina Damasceno
The diabetic syndrome affects pregnancy, contributing to placental functional and structural disruptions and impaired fetal development, with many reports indicating tobacco-associated morbidity and perinatal mortality. In our study, an experimental rat model of diabetes and cigarette smoke exposure in pregnant rats was used to determine the impact of the combination of diabetes and exposure to cigarette smoke during pregnancy on maternal oxidative stress biomarkers and placental and fetal development. Diabetes was induced by streptozotocin, and dams were exposed to cigarette smoke by mainstream smoke generated by a mechanical smoking device and delivered into a chamber...
December 6, 2018: Reproductive Sciences
Rosette Megnekou, Jean Claude Djontu, Benderli C Nana, Jude D Bigoga, Maurice Fotso, Balotin Fogang, Rose F G Leke
BACKGROUND: Plasmodium falciparum infected erythrocytes sequestering in placental tissue release Plasmodium lactate dehydrogenase (pLDH) and histidine-rich protein-II (HRP-II). These proteins can be detected in peripheral blood using monoclonal antibody-based rapid diagnostic tests (RDTs). Nevertheless, studies to evaluate the reliability of RDTs in detecting placental malaria compared with microscopy of placental tissue impression smear (PTIS) as the gold standard are scarce. METHODS: Between August 2013 and January 2015, Giemsa-stained blood smears for peripheral blood smear (Pbs), placental intervillous space (IVS) blood smear and placental tissue impression smear (PTIS)] were prepared from HIV-negative women during delivery at the Marie Reine Medical Health Centre in Yaoundé, Cameroon...
December 4, 2018: Malaria Journal
Anis Haddad, Olfa Zoukar, Houda Mhabrich, Awatef Hajjeji, Raja Faleh
In recent years, the incidence of placenta accreta and associated complications has increased significantly. The authors report the case of a pregnant woman in the 5th month of pregnancy for premature rupture of the membranes. The placenta was inserted low. The evolution was marked spontaneous work followed by the expulsion of the fetus. The delivery of the placenta was haemorrhagic and incomplete. Ultrasonic testing showed a placental fragment integrated in the thickness of the myometrium. Conservative treatment with methotrexate was published a few days later and MRI showed that the anterior uterine sac was filled with blood clots associated with pelvic effusion...
2018: Case Reports in Obstetrics and Gynecology
Rosalba De Nola, Luca Maria Schönauer, Maria Grazia Fiore, Matteo Loverro, Carmine Carriero, Edoardo Di Naro
RATIONALE: Placental site trophoblastic tumor (PSTT) is a very rare malignant tumor, belonging to a family of pregnancy-related illnesses, called gestational trophoblastic diseases (GTD). Less than 300 cases of PSTT have been reported in literature, with an incidence of ≈ 1/50,000-100,000 pregnancies representing only 0.23% to 3.00% of all GTDs. PATIENT CONCERNS: Our report describes 2 additional cases of PSTT outlining their main diagnostic features and the subsequent management...
November 2018: Medicine (Baltimore)
Odessa P Hamidi, Avi Hameroff, Allen Kunselman, William M Curtin, Risha Sinha, Serdar H Ural
Objective To investigate the relationship between maximal placental thickness during routine anatomy scan and birthweight at delivery. Methods This retrospective descriptive study analyzed 200 term, singleton deliveries in 2016 at Penn State Hershey Medical Center. We measured maximal placental thickness in the sagittal plane from the ultrasound images of the placenta obtained at the 18-21-week fetal anatomy screen. The relationship between placental thickness and neonatal birthweight was assessed using Pearson's correlation coefficient (r) with 95% confidence interval (CI)...
December 3, 2018: Journal of Perinatal Medicine
Yuko Otake, Hidenori Kanazawa, Hironori Takahashi, Shigeki Matsubara, Hideharu Sugimoto
OBJECTIVE: To determine the magnetic resonance imaging (MRI)-detectable morphology of the placental cotyledon, we proposed the first cotyledon appearance scores on MRI. Cotyledon appearance scores consist of two subscores: orthogonal and parallel cotyledon appearance scores. These represent cotyledon appearance orthogonal or parallel to the placental thickness, respectively. STUDY DESIGN: This retrospective study was approved by the institutional review board of our hospital...
January 2019: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Alexa A Freedman, Carol J Hogue, Carmen J Marsit, Augustine Rajakumar, Alicia K Smith, Katherine L Grantz, Robert L Goldenberg, Donald J Dudley, George R Saade, Robert M Silver, Karen J Gibbins, Radek Bukowski, Carolyn Drews-Botsch
Low birthweight is associated with both perinatal and long-term morbidity and mortality and may be a result of abnormal placental development and function. Studies in singletons have reported associations between features of placental morphology and birthweight. Evaluating similar associations within twin pairs offers a unique opportunity to control for key confounders shared within a twin pair, including gestational age, parental characteristics, and intrauterine environment, which may otherwise be unfeasible...
November 19, 2018: American Journal of Epidemiology
Ignatia F Reijnders, Annemarie G M G J Mulders, Melissa van der Windt, Eric A P Steegers, Régine P M Steegers-Theunissen
BACKGROUND: Worldwide, placenta-related complications contribute to adverse pregnancy outcomes, such as pre-eclampsia, fetal growth restriction and preterm birth, with implications for the future health of mothers and offspring. The placenta develops in the periconception period and forms the interface between mother and embryo/fetus. An unhealthy periconceptional maternal lifestyle, such as smoking, alcohol and under- and over-nutrition, can detrimentally influence placental development and function...
January 1, 2019: Human Reproduction Update
John P McQuilling, Mitchell Sanders, Lindsay Poland, Mia Sanders, Giacomo Basadonna, Norman E Waldrop, Katie C Mowry
INTRODUCTION: Healing of tendon injuries is often plagued by significant scar formation and compromised biomechanical function. For those with diabetes, these injuries are further complicated by alterations to the extracellular matrix of the tendon, poor circulation, and delayed wound healing; consequently, complications and re-rupture rates for patients with diabetes are reported higher than the typical patient population. Placental derived membranes, specifically dehydrated human amnion/chorion membranes (dACMs), have been utilized clinically as an adhesion barrier, and these membranes have been shown to reduce scarring and aid in tissue repair...
October 26, 2018: Wounds: a Compendium of Clinical Research and Practice
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