Isha Singh, Joanne F Chou, Marinela Capanu, Jennifer Park, Kenneth H Yu, Anna M Varghese, Wungki Park, Alice Zervoudakis, Fergus Keane, Vineet Syan Rolston, Hans Gerdes, Alice C Wei, Pari Shah, Anne Covey, Mark Schattner, Eileen M O'Reilly
BACKGROUND: Acute cholangitis (AC) is a common complication of pancreatic ductal adenocarcinoma (PDAC). Herein, we evaluated outcomes after the first AC episode and predictors of mortality and AC recurrence in patients with stage IV PDAC. METHODS: We conducted a single-center, retrospective observational study using institutional databases. Clinical data and outcomes for patients with stage IV PDAC and at least one documented episode of AC, were assessed. Overall survival (OS) was estimated using the Kaplan-Meier method, and Cox regression model was employed to identify predictors of AC recurrence and mortality...
May 7, 2024: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]