keyword
https://read.qxmd.com/read/37558332/pulmonary-cavitation-with-eosinophilia-in-a-young-man
#21
Vinay V, Paras Verma, Aman Kumar, Shibani Modi, Sushil Kumar Munjal
An 18-year-old man with no noted medical history from Northern India presented with history of fever for 15 days and nocturnal cough for 10 days. He denied breathlessness or wheeze. There was no medical history of asthma. He denied any current sinus-related symptoms, pruritis, skin rashes, lesions, or ulcers, abdominal pain, dysphagia, vomiting or diarrhea, numbness or tingling, joint pain, or food allergy. There was no recent exposure to a patient with TB or history of substance misuse. The patient had sought medical care 7 days before presentation for the same symptoms, and after a chest radiograph was obtained, the patient was started on an antitubercular regimen...
August 2023: Chest
https://read.qxmd.com/read/37497258/prevalence-associated-factors-and-impact-of-adolescent-asthma-in-taiwan-global-asthma-network-phase-i-survey
#22
JOURNAL ARTICLE
Kuan-Wen Su, Dah-Chin Yan, Liang-Shiou Ou, Li-Lun Lin, Chao-Yi Wu, Shu-Jung Huang, Tsung-Chieh Yao, Kuo-Wei Yeh, Jing-Long Huang
BACKGROUND: The prevalence of asthma in Taiwan was increasing in the past 30 years, causing a great impact on adolescent health. This study aimed to investigate the current prevalence, impact, and associated factors of asthma in Taiwanese adolescents. MATERIAL AND METHODS: Parents or guardians provided passive consent at home prior to the survey. Adolescents aged 13-14 years completed a questionnaire survey in 2017 in Taipei, Taiwan. The prevalence, impact, and associated factors of asthma were analyzed...
July 2023: World Allergy Organization Journal
https://read.qxmd.com/read/37456480/daytime-sleepiness-in-children-with-asthma-examining-respiratory-and-non-respiratory-factors
#23
JOURNAL ARTICLE
Abigail R Strang, Lauren Covington, Seema Rani, David Gao, Micayla Flores, Kimberly Canter, Freda Patterson, Aaron Chidekel
Objective Daytime sleepiness is common in youth with asthma (YWA). Treatments designed to mitigate daytime sleepiness in YWA require an understanding of the primary causes of this problem. We examined respiratory- and non-respiratory-related factors associated with daytime sleepiness in YWA. Methods One hundred YWA (eight to 17 years old) were included in a cross-sectional study. Daytime sleepiness, quality of life, anxiety, bedtime cellphone use, and respiratory symptoms were self-reported. Asthma severity, lung function, and the number of prescribed medications were obtained from electronic medical records...
June 2023: Curēus
https://read.qxmd.com/read/37371305/sleep-disordered-breathing-and-its-association-with-nocturnal-enuresis-at-the-primary-schools-in-saudi-arabia-a-cross-sectional-study
#24
JOURNAL ARTICLE
Ali Abdullah Alshehri, Mohamed Soliman Hassan Zaki, Sameh Osama Nour, Wala H Gadi, Basem A Zogel, Samar M Alfaifi, Enas M Masmali, Amani B Aburasain, Mohamed Osama Nour
The correlation between nocturnal enuresis (NE) and sleep-disordered breathing (SDB) was reported. We aim to determine whether there is an association between NE and SDB in children and to assess the prevalence of SDB and NE in primary school children aged 6-12 years in Saudi Arabia. A cross-sectional observational study was conducted among the caregivers of children aged 6-12 years in all Saudi Arabia regions. The data were gathered through a self-administered online questionnaire. It included demographic information, weight and height, and associated comorbidities, in addition to the weekly frequencies of snoring symptoms and of enuresis, as well as of unrefreshing sleep using Likert-type response scales...
June 18, 2023: Children
https://read.qxmd.com/read/37371263/residual-cough-and-asthma-like-symptoms-post-covid-19-in-children
#25
JOURNAL ARTICLE
Abdullah Al-Shamrani, Khalid Al-Shamrani, Maram Al-Otaibi, Ayed Alenazi, Hareth Aldosaimani, Zeyad Aldhalaan, Haleimah Alalkami, Abdullah A Yousef, Sumayyah Kobeisy, Saleh Alharbi
BACKGROUND: Coronavirus disease 2019 (COVID-19) has rapidly spread worldwide and is characterized by different presentations ranging from asymptomatic to severe pneumonia. COVID-19 affects all age groups, including pediatric patients. We observed numerous children complaining of a cough post-COVID-19, even if it was trivial. The most reported persistent symptoms after recovery from COVID-19 were insomnia, coughing, fatigue, dyspnea, loss of taste and/or smell, and headache. To date, residual cough post-COVID-19 has been reported in pediatrics and adolescents...
June 8, 2023: Children
https://read.qxmd.com/read/37238350/mannitol-challenge-to-assess-therapy-response-in-asthmatic-children-an-interventional-cohort-study
#26
JOURNAL ARTICLE
Nikolaos Karantaglis, Fotios Kirvassilis, Elpis Hatziagorou, Antonios Gkantaras, Kalliopi Kontouli, John Tsanakas, Maria Emporiadou
Bronchial provocation tests, such as the mannitol challenge, can be performed to identify and quantify the severity of bronchial hyperresponsiveness in asthmatic patients. Studies of the mannitol challenge as a monitoring tool in asthmatic children are limited. Our primary aim was to compare the bronchial hyperresponsiveness to mannitol in treatment-naive asthmatic children between baseline and three months after receiving the indicated asthma prophylaxis. Twenty-three asthmatic patients aged 4-16 years were analyzed in this prospective cohort study...
April 28, 2023: Children
https://read.qxmd.com/read/37178731/identification-of-cough-variant-asthma-phenotypes-based-on-clinical-and-pathophysiologic-data
#27
MULTICENTER STUDY
Wenzhi Zhan, Feng Wu, Yunhui Zhang, Lin Lin, Wen Li, Wei Luo, Fang Yi, Yuanrong Dai, Suyun Li, Jiangtao Lin, Yadong Yuan, Chen Qiu, Yong Jiang, Limin Zhao, Meihua Chen, Zhongmin Qiu, Ruchong Chen, Jiaxing Xie, Chunxing Guo, Mei Jiang, Xiaohong Yang, Guochao Shi, Dejun Sun, Rongchang Chen, Nanshan Zhong, Huahao Shen, Kefang Lai
BACKGROUND: Cough-variant asthma (CVA) may respond differently to antiasthmatic treatment. There are limited data on the heterogeneity of CVA. OBJECTIVE: We aimed to classify patients with CVA using cluster analysis based on clinicophysiologic parameters and to unveil the underlying molecular pathways of these phenotypes with transcriptomic data of sputum cells. METHODS: We applied k-mean clustering to 342 newly physician-diagnosed patients with CVA from a prospective multicenter observational cohort using 10 prespecified baseline clinical and pathophysiologic variables...
September 2023: Journal of Allergy and Clinical Immunology
https://read.qxmd.com/read/37042567/quality-of-life-in-children-with-asthma-compared-to-healthy-children-a-case-control-study
#28
JOURNAL ARTICLE
Tina Eslambeik, Ali Pourvali, Yazdan Ghandi, Anita Alaghmand, Maryam Zamanian, Amin Tajerian
BACKGROUND: Asthma is a chronic condition characterized by episodic wheezing, cough, and shortness of breath resulting from airway hyperresponsiveness and inflammation. Over 300 million people are affected worldwide, and its prevalence is increasing by 50% every decade. Assessing the quality of life in children with asthma is fundamental, as consistently poor health-related quality of life is associated with poorly controlled asthma. This study is aimed to evaluate and compare factors associated with HRQOL between healthy controls and children with asthma...
April 12, 2023: Journal of Asthma
https://read.qxmd.com/read/36997891/evaluation-of-the-association-between-asthma-and-non-neurogenic-urinary-incontinence-in-children-a-case-control-study
#29
JOURNAL ARTICLE
Elaheh Ziaei, Fatemeh Dorreh, Parsa Yousefichaijan, Roham Sarmadian, Nooshin Sajjadi, Manijeh Kahbazi
BACKGROUND: Asthma is the most common chronic disease in children. Asthma can lead to sleep disorders and psychiatric issues, which are often accompanied by urinary incontinence in children. Furthermore, several studies have shown a relationship between allergic diseases and urinary incontinence. This study aims to examine the association between asthma and non-neurogenic urinary incontinence. MATERIALS AND METHODS: This case-control study included 314 children over three years old referred to Amir Kabir Hospital; 157 with asthma and 157 without asthma...
March 30, 2023: BMC Pediatrics
https://read.qxmd.com/read/36910102/nocturnal-continuous-positive-airway-pressure-offers-symptomatic-benefit-in-excessive-dynamic-airway-collapse-despite-normal-sleep-study
#30
JOURNAL ARTICLE
Louise Olley, Joerg Steier, Georgios Kaltsakas
Excessive dynamic airway collapse (EDAC) and tracheobronchomalacia (TBM) cause debilitating symptoms yet are often misdiagnosed as asthma or chronic obstructive pulmonary disease (COPD). EDAC/TBM should be considered in all cases of obstructive ventilatory defect refractory to medical management. Diagnosis is made with flexible bronchoscopy and/or inspiratory and expiratory phase computed tomography (CT) scans. Treatment should be individualised and "pneumatic stenting" with the use of continuous positive airway pressure (CPAP) may lead to symptomatic relief, and in some cases regardless of the degree of collapse or absence of sleep disordered breathing in overnight oximetry...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36868950/questionnaire-for-diagnosing-asthma-copd-overlap-in-copd-development-of-aco-screening-questionnaire-aco-q
#31
JOURNAL ARTICLE
Yuki Suzuki, Hiroyuki Nagase, Hikaru Toyota, Sho Ohyatsu, Konomi Kobayashi, Yuri Takeshita, Yuuki Uehara, Saya Hattori, Mana Ishizuka, Hirokazu Sakasegawa, Michio Kuramochi, Tadashi Kohyama, Naoya Sugimoto
BACKGROUND: The considerable prevalence and worse outcomes of asthma-COPD overlap (ACO) in COPD have been reported, and optimal introduction of ICS is essential for ACO. However, diagnostic criteria for ACO consist of multiple laboratory tests, which is challenging during this COVID-19 era. The purpose of this study was to create a simple questionnaire to diagnose ACO in patients with COPD. METHODS: Among 100 COPD patients, 53 were diagnosed with ACO based on the Japanese Respiratory Society Guidelines for ACO...
March 1, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/36847658/small-airway-disease-and-asthma-control
#32
JOURNAL ARTICLE
Seda Beyhan Sagmen, Berrin Zinnet Eraslan, Ersin Demirer, Nesrin Kiral, Sevda Comert
AIM: Maximum mid-expiratory flow (MMEF) is one of the pulmonary function tests that report small airway disease. Our study aimed to investigate the role of MMEF values in asthma control, the prevalence of small airway disease, and their effect on asthma control in patients with asthma with normal forced expiratory volume in one second (FEV1 ) values. MATERIAL AND METHOD: Patients who presented to the Chest Diseases outpatient clinic of our hospital between 2018 and 2019 and were diagnosed as having asthma were included in the study...
March 16, 2023: Journal of Asthma
https://read.qxmd.com/read/36796546/small-airway-dysfunction-in-asthmatic-patients-treated-with-as-needed-saba-monotherapy-a-perfect-storm
#33
JOURNAL ARTICLE
Marcello Cottini, Carlo Lombardi, Pasquale Comberiati, Massimo Landi, Alvise Berti, Laura Ventura
BACKGROUND: Short-acting beta agonist (SABA)-only treatment is associated with poor asthma control and adverse clinical outcomes. The importance of small airway dysfunction (SAD) is increasingly recognized in asthma, but less is known in patients using SABA-only therapy. We aimed to investigate the impact of SAD on asthma control in an unselected cohort of 60 adults with physician-diagnosed intermittent asthma treated with as-needed SABA monotherapy. METHODS: All patients underwent standard spirometry and impulse oscillometry (IOS) at the first visit and were stratified by the presence of SAD defined by IOS (fall in resistance 5-20 Hz [R5-R20]>0...
February 14, 2023: Respiratory Medicine
https://read.qxmd.com/read/36762119/does-pomegranate-extract-supplementation-improve-the-clinical-symptoms-of-patients-with-allergic-asthma-a-double-blind-randomized-placebo-controlled-trial
#34
JOURNAL ARTICLE
Seyed Ahmad Hosseini, Zainab Shateri, Farhad Abolnezhadian, Elham Maraghi, Maryam Haddadzadeh Shoushtari, Marzie Zilaee
Background: Asthma essentially represents a chronic inflammatory disease that manifests as a lifelong condition with different severity throughout the life of patients with asthma. Pomegranate holds three times the antioxidant activity compared to other polyphenol-rich food sources like green tea, which may positively impact asthma. Aim of the study: This research aimed to investigate the pomegranate supplementation influences clinical symptoms, eosinophil, basophil, and neutrophil counts in patients with allergic asthma...
2023: Frontiers in Pharmacology
https://read.qxmd.com/read/36715436/dose-dependent-relationship-between-nocturnal-gastroesophageal-reflux-and-chronic-rhinosinusitis-in-a-middle-aged-population-results-from-the-scapis-pilot
#35
JOURNAL ARTICLE
J Bergqvist, M Bove, A Andersson, L Schiöler, J Hellgren
BACKGROUND: Gastroesophageal reflux (GER) has been associated with several upper- and lower-airway diseases. It would be plausible if nightly occurring reflux via laryngopharyngeal reflux (LPR) might affect the upper airways. Still, the role of nocturnal gastroesophageal reflux (nGER) in chronic rhinosinusitis (CRS) is not fully established. The aim of this population-based study was to investigate the association between nGER and CRS. METHODOLOGY: This cross-sectional population-based study comprises 1,111 randomly selected subjects from Gothenburg, Sweden, aged 50-64 years...
January 30, 2023: Rhinology
https://read.qxmd.com/read/36655551/nighttime-continuous-contactless-smartphone-based-cough-monitoring-for-the-ward-a-validation-study
#36
JOURNAL ARTICLE
Filipe Barata, David Cleres, Peter Tinschert, Iris Shih, Frank Rassouli, Maximilian Boesch, Martin Brutsche, Elgar Fleisch
BACKGROUND: Clinical deterioration can go unnoticed in hospital wards for hours. Mobile technologies such as wearables and smartphones enable automated, continuous, non-invasive ward monitoring and allow the detection of subtle changes in vital signs. Cough holds great potential for monitoring through mobile technologies on the ward as it is not only a symptom of prevalent respiratory diseases such as asthma, lung cancer, and COVID-19 but also a predictor of acute health deterioration...
January 17, 2023: JMIR Formative Research
https://read.qxmd.com/read/36536328/spinal-manipulation-and-mobilisation-in-the-treatment-of-infants-children-and-adolescents-a-systematic-scoping-review
#37
REVIEW
Nikki Milne, Lauren Longeri, Anokhi Patel, Jan Pool, Kenneth Olson, Annalie Basson, Anita R Gross
PURPOSE: To i) identify and map the available evidence regarding effectiveness and harms of spinal manipulation and mobilisation for infants, children and adolescents with a broad range of conditions; ii) identify and synthesise policies, regulations, position statements and practice guidelines informing their clinical use. DESIGN: Systematic scoping review, utilising four electronic databases (PubMed, Embase, CINHAL and Cochrane) and grey literature from root to 4th February 2021...
December 19, 2022: BMC Pediatrics
https://read.qxmd.com/read/36505412/bmal1-foxa2-induced-rhythmic-fluctuations-in-il-6-contribute-to-nocturnal-asthma-attacks
#38
JOURNAL ARTICLE
Lingling Tang, Li Liu, Xianhong Sun, Po Hu, Hui Zhang, Bohan Wang, Xiaona Zhang, Jinjin Jiang, Xia Zhao, Xiaolu Shi
UNLABELLED: The circadian clock is closely associated with inflammatory reactions. Increased inflammatory cytokine levels have been detected in the airways of nocturnal asthma. However, the mechanisms that contribute to the nocturnal increase in inflammatory responses and the relationship with circadian clock remain unknown. METHODS: Inflammatory cytokine levels were measured in asthma patients with and without nocturnal symptoms. Allergic airway disease was induced in mice by ovalbumin (OVA), and different periods of light/dark cycles were used to induce circadian rhythm disorders...
2022: Frontiers in Immunology
https://read.qxmd.com/read/36427647/multi-dimensional-analyses-of-the-associations-between-depression-nocturnal-awakening-and-asthmatic-outcomes
#39
JOURNAL ARTICLE
Zhigang Hu, Yufeng Tian, Xinyu Song, Ke Hu, Ailan Yang
BACKGROUND: Depression plays an important role in the occurrence and development of asthma. Nocturnal awakening secondary to asthma is a crucial sign of the deterioration of asthmatic outcomes. This study plans to determine the associations between depression, nocturnal awakening and asthmatic outcomes by using multi-dimensional analyses. METHODS: Study population came from the Adult Asthma Call-Back Survey 2013-2017. Multivariable regression analysis with binomial or Poisson models, dose-dependent analysis and mediation analysis were used to explore the associations between depression and nocturnal awakening with asthmatic episodes/attacks, emergency room (ER) and hospital visits...
November 22, 2022: Journal of Affective Disorders
https://read.qxmd.com/read/36352399/temperature-controlled-laminar-airflow-tla-in-symptomatic-severe-asthma-a-post-hoc-analysis-of-severe-exacerbations-quality-of-life-and-health-economics
#40
JOURNAL ARTICLE
A J Chauhan, G Eriksson, W Storrar, T Brown, S Peterson, F Radner, L G D'Cruz, P Miller, L Bjermer
PURPOSE: Uncontrolled severe asthma constitutes a major economic burden to society. Add-ons to standard inhaled treatments include inexpensive oral corticosteroids and expensive biologics. Nocturnal treatment with Temperature-controlled Laminar Airflow (TLA; Airsonett®) could be an effective, safe and cheaper alternative. The potential of TLA in reducing severe asthma exacerbations was addressed in a recent randomised placebo-controlled trial (RCT) in patients with severe asthma (Global Initiative for Asthma (GINA) step 4/5), but the results were inconclusive...
November 9, 2022: BMC Pulmonary Medicine
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