Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#21
REVIEW
Erin Forbes, Amanda L Baker, Ben Britton, Kerrie Clover, Eliza Skelton, Lyndell Moore, Tonelle Handley, Sharon Oultram, Christopher Oldmeadow, Alison Gibberd, Kristen McCarter
UNLABELLED: Procedural anxiety is a concern for a number of patients undergoing radiation therapy. While procedural anxiety is often treated pharmacologically, there is a clinical need for effective alternative strategies for patients who are contraindicated from medication use, and those who prefer not to take unnecessary medications. OBJECTIVES: The primary objective was to assess the efficacy of nonpharmacological interventions delivered to adults with cancer, in the radiation oncology department, just prior to, or during radiation therapy, in reducing levels of self-reported procedural anxiety...
October 6, 2023: Cancer Medicine
#22
JOURNAL ARTICLE
P Forte, V Abate, I Bolognini, O Mazzoni, V Quagliariello, N Maurea, D Di Bonito, E Quarata, G Migliaccio, M Petrillo, D Barberio
Mindfulness-based stress reduction, a complementary and alternative therapy, is able to decrease cancer-related fatigue, and stress and to improve the quality of life in cancer patients. Some studies evaluated if mindfulness-based stress reduction could improve some cardiometabolic and cancer risk factors, including systemic chemokines, growth factors, and pro-inflammatory biomarkers (e.g., C-reactive protein, Interleukin-1). In this narrative review, we highlight the pleiotropic beneficial effects of mindfulness-based stress reduction and its clinical impact on cardiovascular and cancer risk factors among patients with cancer in different stages...
September 2023: European Review for Medical and Pharmacological Sciences
#23
JOURNAL ARTICLE
Lidia Gaffke, Natalia Firyn, Estera Rintz, Karolina Pierzynowska, Ewa Piotrowska, Hanna Mazur-Marzec, Grzegorz Węgrzyn
Mucopolysaccharidoses (MPS) are a group of inherited disorders, caused by mutations in the genes coding for proteins involved (directly or indirectly) in glycosaminoglycan (GAG) degradation. A lack or drastically decreased residual activity of a GAG-degrading enzyme leads to the storage of these compounds, thus damaging proper functions of different cells, including neurons. The disease leads to serious psycho-motor dysfunctions and death before reaching the adulthood. Until now, induction of the autophagy process was considered as one of the therapeutic strategies for treatment of diseases caused by protein aggregation (Alzheimer's, Parkinson's, and Huntington's diseases)...
September 12, 2023: Archives of Biochemistry and Biophysics
#24
JOURNAL ARTICLE
Daniela C Rosenberger, Daniel Segelcke, Esther M Pogatzki-Zahn
PURPOSE OF REVIEW: Acute pain is an expected consequence of a surgery, but it is far from being well controlled, due to its complex bio-psycho-social nature. One major complication of acute pain is its risk of persistency beyond healing. This so-called chronic post-surgical pain (CPSP) is defined as new or increased pain due to surgery that lasts for at least 3 months after surgery. CPSP is frequent and constitutes an important socioeconomic challenge with significant impact on patients' quality of life...
September 8, 2023: Current Opinion in Supportive and Palliative Care
#25
REVIEW
A Vila-Farinas, M Pérez-Rios, A Montes-Martinez, A Ruano-Ravina, Ariadna Forray, J Rey-Brandariz, C Candal-Pedreira, E Fernández, B Casal-Acción, L Varela-Lema
OBJECTIVE: To carry out a systematic review of systematic reviews with an update of the existing evidence relating to a broad range of smoking cessation interventions, including psycho-social, digital and pharmacologic interventions, for pregnant women. DATA-SOURCES: Search was conducted in March 2022 in PubMed, EMBASE, and Cochrane in two stages: 1) a search of systematic reviews and meta-analyses, published from January 2012 through January 2022; 2) an update of those that fulfilled eligibility criteria reproducing the primary search strategy...
September 3, 2023: Addictive Behaviors
#26
REVIEW
Clara Grosso, Marlene Santos, M Fátima Barroso
The brain's sensitivity to oxidative stress and neuronal cell death requires effective pharmacotherapy approaches. Current pharmacological therapies are frequently ineffective and display negative side effects. Bioactive chemicals found in plants may provide a potential alternative due to their antioxidant and neuroprotective properties and can be used in therapy and the management of a variety of neuropsychiatric, neurodevelopmental, and neurodegenerative illnesses. Several natural products, including vitamin C, Cammelia sinensis polyphenols, Hypericum perforatum , and Crocus sativus have shown promise in lowering oxidative stress and treating symptoms of major depressive disorder (MDD)...
August 11, 2023: Antioxidants (Basel, Switzerland)
#27
RANDOMIZED CONTROLLED TRIAL
Sylvie Willems, Vincent Didone, Carmen Cabello Fernandez, Gael Delrue, Hichem Slama, Patrick Fery, Julien Goin, Clara Della Libera, Fabienne Collette
BACKGROUND: Cognitive difficulties are a frequent complaint in long COVID and persist for more than a year post- infection. There is a lack of evidence-based data on effective intervention strategies. Non-pharmacological intervention programs that are used with other neurological populations have not yet been the subject of controlled trials. COVCOG is a multicentric, randomized trial comparing cognitive intervention and a cognitive-behavioural counselling. METHODS/DESIGN: Patients with long covid are selected and recruited at least three months post-infection...
August 18, 2023: BMC Neurology
#28
REVIEW
Hugo Geerts, Silke Bergeler, William W Lytton, Piet H van der Graaf
Successful clinical development of new therapeutic interventions is notoriously difficult, especially in neurodegenerative diseases, where predictive biomarkers are scarce and functional improvement is often based on patient's perception, captured by structured interviews. As a consequence, mechanistic modeling of the processes relevant to therapeutic interventions in CNS disorders has been lagging behind other disease indications, probably because of the perceived complexity of the brain. However in this report, we develop the argument that a combination of Computational Neurosciences and Quantitative Systems Pharmacology (QSP) modeling of molecular pathways is a powerful simulation tool to enhance the probability of successful drug development for neurodegenerative diseases...
July 28, 2023: Journal of Pharmacokinetics and Pharmacodynamics
#29
JOURNAL ARTICLE
(no author information available yet)
Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in school-age children, with 30%-50% persisting into adulthood. In addition, adult ADHD patients have more comorbidities, are more difficult to identify, and have a wider range of impairments on individual function, thereby leading to more serious adverse effects on medical care, economy and society. This consensus establishes the diagnose of adult ADHD based on the 11th edition of International Classification of Diseases (ICD-11), determines the treatment plans based on the etiology and pathogenesis of the disease, recommends psycho-stimulants as the first-line pharmacotherapy for adult ADHD and selective noradrenalin reuptake inhibitors (NARIs) as the second-line pharmacotherapy to reduce the core symptoms, and combines non-pharmacological treatments, such as cognitive behavioral therapy, health education and lifestyle training, aiming to improve patients' functioning and quality of life to the utmost...
July 25, 2023: Zhonghua Yi Xue za Zhi [Chinese medical journal]
#30
JOURNAL ARTICLE
Damiano Baldassarre, Licia Iacoviello, Roberta Baetta, Maria Carla Roncaglioni, Gianluigi Condorelli, Giuseppe Remuzzi, Gianfranco Gensini, Luigi Frati, Walter Ricciardi, Pier Giulio Conaldi, Antonio Uccelli, Fabio Blandini, Silvano Bosari, Giovanni Scambia, Massimo Fini, Antonio Di Malta, Mauro Amato, Fabrizio Veglia, Alice Bonomi, Catherine Klersy, Francesca Colazzo, Martino Pengo, Francesca Gorini, Luciana Auteri, Giuseppe Ferrante, Marta Baviera, Giuseppe Ambrosio, Alberico Catapano, Alessandro Gialluisi, Alexis Elias Malavazos, Serenella Castelvecchio, Massimiliano Marco Corsi-Romanelli, Rosanna Cardani, Maria Teresa La Rovere, Valentina Agnese, Bianca Pane, Daniele Prati, Laura Spinardi, Giovanna Liuzzo, Eloisa Arbustini, Maurizio Volterrani, Marco Visconti, José Pablo Werba, Stefano Genovese, Grzegorz Bilo, Cecilia Invitti, Anna Di Blasio, Carolina Lombardi, Andrea Faini, Debora Rosa, Luisa Ojeda-Fernández, Andreana Foresta, Amalia De Curtis, Augusto Di Castelnuovo, Simonetta Scalvini, Antonia Pierobon, Alessandra Gorini, Luca Valenti, Livio Luzi, Annarosa Racca, Manuela Bandi, Elena Tremoli, Lorenzo Menicanti, Gianfranco Parati, Giulio Pompilio
INTRODUCTION: Prevention of cardiovascular disease (CVD) is of key importance in reducing morbidity, disability and mortality worldwide. Observational studies suggest that digital health interventions can be an effective strategy to reduce cardiovascular (CV) risk. However, evidence from large randomised clinical trials is lacking. METHODS AND ANALYSIS: The CV-PREVITAL study is a multicentre, prospective, randomised, controlled, open-label interventional trial designed to compare the effectiveness of an educational and motivational mobile health (mHealth) intervention versus usual care in reducing CV risk...
July 14, 2023: BMJ Open
#31
JOURNAL ARTICLE
Roberta Bevilacqua, Elvira Maranesi, Elisa Felici, Arianna Margaritini, Giulio Amabili, Federico Barbarossa, Anna Rita Bonfigli, Giuseppe Pelliccioni, Lucia Paciaroni
INTRODUCTION: The aging of the population and the high incidence of those over 80 lead to an inevitable increase in chronic degenerative diseases, such as dementia, resulting in increased morbidity and disability. Treatment of people with dementia involves both pharmacological and non-pharmacological interventions. In particular, robot-assisted therapy is a potentially useful treatment for dementia as it has the advantage of improving mood, encouraging social interaction and communication...
2023: Frontiers in Public Health
#32
JOURNAL ARTICLE
Wenjing Gao, Tao Pan, Guangyuan Fan, Jian Cui, Tingting Wang, Nan Huang, Changyou Jiang, Lan Ma, Feifei Wang, Xing Liu, Qiumin Le
Introduction: A growing body of evidence suggests that parental substance abuse, even prior to conception, may induce phenotypic changes in offspring. Parental opioid exposure has been shown to affect developmental processes, induce memory deficits, and lead to psycho-emotional disorders in offspring. However, how parental, especially paternal, chronic drug exposure affects offspring remains unexplored. Methods: Adult male rats were subjected to 31 days of heroin self-administration followed by mating with naïve females...
2023: Frontiers in Pharmacology
#33
JOURNAL ARTICLE
Jorge A Lara-Vargas, Angélica A Pérez-Reyes, Juan P Núñez-Urquiza, Dulce M Navarrete de la O, Hermes Ilarraza-Lomelí, Eduardo A Leyva-Valadez, María E González-Rentería, Minerva Romero-Rendón, Marcos Ponce-de-León-Espíndola, Martha C Maldonado-Ramírez, Aquiles Rubio-Blancas
BACKGROUND: Obesity is a multifactorial disorder characterized by increased body adiposity with a wide prevalence in our country, at any age, and linked to major adverse consequences, including the development of heart disease. Cardiac rehabilitation (CR) programs are interdisciplinary interventions aimed not only at restoring the lost functionality of patients who have suffered a cardiovascular outcome, but also at correcting those risk factors that led to it and that interfere with its adaptive results...
June 27, 2023: Archivos de Cardiología de México
#34
JOURNAL ARTICLE
Yannick Boddez, Sara Scheveneels, Pieter Van Dessel
BACKGROUND AND OBJECTIVES: Models are omnipresent in science. We introduce a novel framework to achieve more effective modelling practices in general psychology and experimental psychopathology. METHOD: We analyze three types of models that are common in psychology: laboratory models, computational models, and cognitive models. We then evaluate two common ways to assess the translational value of models (phenomenological similarity and deep similarity) as well as an arguably underappreciated way (functional similarity)...
September 2023: Journal of Behavior Therapy and Experimental Psychiatry
#35
JOURNAL ARTICLE
Chiara Buizza, Eleno Franco, Alberto Ghilardi
The aim of this study was to assess the therapeutic effectiveness of biofeedback, in a medical center's routine for treating vestibular disorders, reducing emotional, functional, and physical disability at three-month follow-up. A total of 197 outpatients were recruited from a medical center to treat vestibular disorders. Patients in the control group received treatment as usual, consisting of one monthly visit with an otolaryngologist and pharmacological treatment specific for vertigo, while the experimental group attended biofeedback training...
May 25, 2023: Applied Psychophysiology and Biofeedback
#36
REVIEW
Jessica M Yingst, Matthew Carrillo, Kimberly H Chan, Karen Choi, Joseph Dao, Pallavi Kulkarni, Candace Bordner, Neerav Goyal, Jonathan Foulds, Rebecca Bascom
OBJECTIVES: Continued smoking after cancer diagnosis is associated with worse outcomes, however, many persons diagnosed with cancer who smoke are unable to quit successfully. Effective interventions are needed to promote quitting in this population. The purpose of this systematic review is to understand the most effective interventions for smoking cessation among persons with cancer and to identify gaps in knowledge and methodology to suggest directions for future research. METHODS: Three electronic databases (The Cochrane Central Register of Controlled trials, MEDLINE, and EMBASE) were searched for studies of smoking cessation interventions among persons with cancer, published up to 1 July 2021...
May 24, 2023: Psycho-oncology
#37
Hong-Li Chen, Cheng Li, Jing Wang, Yang Fei, Min Min, Yue Zhao, En-Fang Shan, Yue-Heng Yin, Chong-Yuan Liu, Xian-Wen Li
BACKGROUND: Feeding and eating disorders related to cognitive and psycho-behavioral symptoms are strongly associated with health status in persons with dementia (PWD). Non-pharmacological interventions have been the priority selection to address this significant issue. However, the direct targets of non-pharmacological interventions are unclear and there is no consistent evidence of recommendations on the intervention of different dementia stages and the settings of intervention practice...
May 18, 2023: Journal of Alzheimer's Disease: JAD
#38
JOURNAL ARTICLE
Chloe S Zimmerman, Simona Temereanca, Dylan Daniels, Cooper Penner, Tariq Cannonier, Stephanie R Jones, Catherine Kerr
Cancer-related fatigue (CRF) is a common and burdensome, often long-term side effect of cancer and its treatment. Many non-pharmacological treatments have been investigated as possible CRF therapies, including exercise, nutrition, health/psycho-education, and mind-body therapies. However, studies directly comparing the efficacy of these treatments in randomized controlled trials are lacking. To fill this gap, we conducted a parallel single blind randomized controlled pilot efficacy trial with women with CRF to directly compare the effects of Qigong (a form of mind-body intervention) (n = 11) to an intervention that combined strength and aerobic exercise, plant-based nutrition and health/psycho-education (n = 13) in a per protocol analysis...
2023: Integrative Cancer Therapies
#39
JOURNAL ARTICLE
Yoshinobu Matsuda, Hitoshi Tanimukai, Shinichiro Inoue, Takatoshi Hirayama, Yusuke Kanno, Yuichi Kitaura, Shuji Inada, Koji Sugano, Masafumi Yoshimura, Saki Harashima, Saho Wada, Takaaki Hasegawa, Yoshiaki Okamoto, Chikako Dotani, Mari Takeuchi, Jun Kako, Ryoichi Sadahiro, Yasuhiro Kishi, Megumi Uchida, Asao Ogawa, Masatoshi Inagaki, Toru Okuyama
OBJECTIVE: The Japanese Psycho-Oncology Society and the Japanese Association of Supportive Care in Cancer have recently revised the clinical practice guidelines for delirium in adult cancer patients. This article reports the process of developing the revised guidelines and summarizes the recommendations made. METHODS: The guidelines were developed in accordance with the Medical Information Network Distribution Service creation procedures. The guideline development group, consisting of multi-disciplinary members, created three new clinical questions: non-pharmacological intervention and antipsychotics for the prevention of delirium and trazodone for the management of delirium...
May 15, 2023: Japanese Journal of Clinical Oncology
#40
JOURNAL ARTICLE
Loredana Buonaccorso, Stefania Fugazzaro, Cristina Autelitano, Elisabetta Bertocchi, Monia Allisen Accogli, Monica Denti, Stefania Costi, Gianfranco Martucci, Luca Braglia, Maria Chiara Bassi, Silvia Tanzi
BACKGROUND: Key elements in cancer cachexia (CC) management are personalized and multimodal interventions, but it is hard for some patients to follow programs based on several components. We examined the feasibility of a bimodal intervention, including a psycho-educational component and exercises, to support patients and their caregivers in managing CC; Methods: Prospective mixed-methods pilot study explored feasibility data, changes in patient-reported outcomes, and performance outcomes over time in a convenient sample of 30 consecutive CC patients and their caregivers...
March 30, 2023: Cancers
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
