Evangelos C Fradelos, Victoria Alikari, Konstantinos Tsaras, Ioanna V Papathanasiou, Foteini Tzavella, Dimitrios Papagiannis, Sofia Zyga
Introduction: Patients undergoing hemodialysis (HD) are faced with bearing this burden and report poor mental health. Spirituality can be a key factor in managing these problems among HD patients. Aim: This cross-sectional study aimed at exploring possible factors that are associated with psychological distress among HD patients and testing its relation to spirituality. Methods: HD patients were recruited from six dialysis units in Greece...
January 2021: Medicine and pharmacy reports
Matias Lopez Avecilla, Mariana Corneli, Gisela Killinger, Carlos Rodriguez Correa
Background: Metastatic cardiac calcifications are often seen in patients with renal failure and dialysis associated with vascular calcification and calcifications in other organs. There is little to no evidence of metastatic cardiac calcification in patients with a history of rickets. Case summary: A 40-year-old patient with a history of rickets treated in infancy and no personal history of cardiovascular or renal disease came for a periodical examination. Transthoracic echocardiogram showed an important calcification in the mitral annulus and the mitro-aortic junction...
December 2020: European Heart Journal. Case Reports
Xiaoyi Guo, Wei Zhou, Qun Lu, Aiyan Du, Yinghua Cai, Yijie Ding
Dry weight is the normal weight of hemodialysis patients after hemodialysis. If the amount of water in diabetes is too much (during hemodialysis), the patient will experience hypotension and shock symptoms. Therefore, the correct assessment of the patient's dry weight is clinically important. These methods all rely on professional instruments and technicians, which are time-consuming and labor-intensive. To avoid this limitation, we hope to use machine learning methods on patients. This study collected demographic and anthropometric data of 476 hemodialysis patients, including age, gender, blood pressure (BP), body mass index (BMI), years of dialysis (YD), and heart rate (HR)...
2021: BioMed Research International
Tarek A Ghonimi, Abdullah Hamad, Zafer Iqbal, Fadumo Yasin, Farrukh Ali, Sahar Ismail, Rania Abdul Aziz, Fadwa Al-Ali
BACKGROUND: End-stage kidney disease (ESKD) patients on maintenance renal replacement therapy (RRT) have far lower life spans than those of the general population. No previous studies have been performed to assess the mortality of dialysis patients in the State of Qatar. We designed this study to assess the mortality of dialysis patients in Qatar and the impact of dialysis modality. METHODS: All chronic ambulatory dialysis patients (both on hemodialysis (HD) and peritoneal dialysis (PD) between 2014 and 2016) were included in the study, whereas patients undergoing dialysis for less than 3 months were excluded...
2021: Qatar Medical Journal
Mohamed Omer, Zeenat Yousuf Bhat, Nanette Fonte, Nashat Imran, James Sondheimer, Yahya Osman-Malik
Materials and Methods: 24 patients with CUA and on RRT were evaluated at Detroit Medical Center from 2007 to 2016. Skin biopsy was used in almost all patients, along with the radiological and clinical findings. The patient's clinical and paraclinical data were retrieved from the electronic medical records. The effect of treatment modalities and the underlying hyperparathyroidism management were compared to the clinical outcomes using appropriate statistical tests. Results: Twenty-one patients were on hemodialysis, two patients received renal transplants, and one patient was on peritoneal dialysis...
2021: International Journal of Nephrology
Cheng-Hao Sung, Bang-Gee Hsu, Jen-Pi Tasi, Chih-Hsien Wang, Chiu-Huang Kuo
Background: Adipocyte fatty acid-binding protein (A-FABP) plays essential roles in lipolysis, insulin resistance, and atherosclerosis. This study aimed to evaluate the relationship between serum A-FABP levels and carotid-femoral pulse wave velocity (cfPWV) in peritoneal dialysis (PD) patients. Methods: This study obtained fasting blood samples from 76 PD patients. A validated tonometry system was used to measure cfPWV. Patients with cfPWV values >10 m/s were classified into the high arterial stiffness group, whereas patients with values ≤10 m/s were classified into the low arterial stiffness group, according to the ESH-ESC 2013 guidelines...
2021: International Journal of Hypertension
Krishna Poinen, Lee Er, Michael A Copland, Rajinder S Singh, Mark Canney
Background: Despite the recognized benefits of home therapies for patients and the health care system, most individuals with kidney failure in Canada continue to be initiated on in-center hemodialysis. To optimize recruitment to home therapies, there is a need for programs to better understand the extent to which potential candidates are not successfully initiated on these therapies. Objective: We aimed to quantify missed opportunities to recruit patients to home therapies and explore where in the modality selection process this occurs...
2021: Canadian Journal of Kidney Health and Disease
Katherine Giuliano, Y Julia Chen, Kristen Coletti, Caitlin O'Brien, Eric Jelin, Alejandro Garcia
We present the case of a 16-year-old female with systemic lupus erythematosus who presented with shock of unclear etiology, refractory to fluid resuscitation and triple vasopressors. She suffered pulseless electrical activity and underwent cannulation onto veno-arterial extracorporeal membrane oxygenation (ECMO). After cannulation, it was discovered she had intentionally overdosed on her home medication, amlodipine, a calcium channel blocker (CCB). She was supported on ECMO, treated with IV calcium and insulin, and was able to be weaned off ECMO after 4 days...
February 2021: Journal of Surgical Case Reports
Francesco Crafa, Amalia Rosaria Rita Rossetti, Augusto Striano, Mario Baiamonte, Francesco Esposito
The nephron-sparing techniques allow the excision of kidney tumors preserving renal function and ensuring adequate oncological results. We describe a case of a 77-year-old patient who underwent an ex vivo partial nephrectomy with orthotopic autotransplantation for kidney cancer. The postoperative course was marked by bleeding which required radiological embolization. Postoperative dialysis was required for about 1 month. The anatomopathological examination showed a clear cell carcinoma staged pT1b, pNX, R0...
February 2021: Journal of Surgical Case Reports
Ewa Wojtaszek, Urszula Oldakowska-Jedynak, Marlena Kwiatkowska, Tomasz Glogowski, Jolanta Malyszko
Patients with chronic kidney disease (CKD) are at a high risk for cardiovascular disease (CVD), and approximately half of all deaths among patients with CKD are a direct result of CVD. The premature cardiovascular disease extends from mild to moderate CKD stages, and the severity of CVD and the risk of death increase with a decline in kidney function. Successful kidney transplantation significantly decreases the risk of death relative to long-term dialysis treatment; nevertheless, the prevalence of CVD remains high and is responsible for approximately 20-35% of mortality in renal transplant recipients...
2021: Oxidative Medicine and Cellular Longevity
Isabelle Dominique Tomacruz, Paolo Nikolai So, Renz Michael Pasilan, Jameel Kristine Camenforte, Maria Isabel Duavit
Aim: Data published on COVID-19 in the Filipino population, particularly those with end stage kidney disease (ESKD) are still lacking. Methods: We performed a retrospective, observational study of 68 ESKD patients admitted with COVID-19 infection at a tertiary hospital in Metro Manila, Philippines from April 1, 2020 to July 31, 2020. We compared the clinical features, baseline laboratory data, treatment strategies and short-term outcomes between those who survived and those who died...
2021: International Journal of Nephrology and Renovascular Disease
Kenichi Izumi, Yasuhiro Ono
84-year-old woman had been diagnosed hypothyroidism before, but she did not take tablets of thyroid hormone prescribed. Anorexia and decreased consciousness level were discovered by workers of the facility. Her family doctor found thyroid function abnormality as a cause, and she was introduced to our hospital to treat because the whole body condition was bad. Her physical examination was observed that JCS was 3-10. Laboratory examination showed that TSH 562.81 μIU/mL, fT4 0.40 ng/mL, pH 7.33, and Na 124 mEq/L...
2021: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
Serban M Maierean, Matthew J Oliver
BACKGROUND: Peritoneal dialysis (PD) is underutilized in many parts of the world despite pro-PD health policies. The physical and cognitive demands of PD means that over half of eligible patients require some form of assistance. As such, many countries now offer assisted PD (aPD) programs to help patients start or stay on PD as opposed to in-center hemodialysis (HD). In order to evaluate the potential scope of aPD, it is important to review the outcomes and cost considerations of aPD...
February 24, 2021: Blood Purification
Mario Cozzolino, Andrea Galassi, Paola Ciceri
Patients affected by chronic kidney disease (CKD) have a greater risk of mortality than the general population. Fatal cardiovascular events are the most frequent cause of death in CKD patients, especially in the late stages of disease. Derangement of mineral metabolism and hyperphosphataemia are currently accepted as pivotal triggers of these vascular complications. Phosphate binders represent the common strategy to counteract hyperphosphataemia in dialysis patients. Several studies have reported a reduction in mortality risk in dialysis patients receiving phosphate binders compared with untreated patients, independent of the class of binder prescribed...
February 2021: Clinical Kidney Journal
Lu Dai, Longkai Li, Helen Erlandsson, Armand M G Jaminon, Abdul Rashid Qureshi, Jonaz Ripsweden, Torkel B Brismar, Anna Witasp, Olof Heimbürger, Hanne Skou Jørgensen, Peter Barany, Bengt Lindholm, Pieter Evenepoel, Leon J Schurgers, Peter Stenvinkel
Patients with chronic kidney disease (CKD) suffer from vitamin K deficiency and are at high risk of vascular calcification (VC) and premature death. We investigated the association of functional vitamin K deficiency with all-cause mortality and whether this association is modified by the presence of VC in CKD stage 5 (CKD G5). Plasma dephosphorylated-uncarboxylated matrix Gla-protein (dp-ucMGP), a circulating marker of functional vitamin K deficiency, and other laboratory and clinical data were determined in 493 CKD G5 patients...
2021: PloS One
Hayfa H Almutary
BACKGROUND: The persistent global increase in chronic kidney disease (CKD) prevalence highlights the importance of providing patients with sufficient knowledge to allow them to self-manage their disease. OBJECTIVES: To gain insights into non-dialysis CKD patients' knowledge of their disease, and assess associations between knowledge and sample characteristics. DESIGN: A descriptive cross-sectional design was undertaken. PARTICIPANTS: A convenience sample of 203 stages 3-5 CKD patients was recruited...
February 24, 2021: Journal of Renal Care
Francesco Pizzarelli, Vincenzo Cantaluppi, Vincenzo Panichi, Alessandro Toccafondi, Giuseppe Ferro, Serena Farruggio, Elena Grossini, Pietro Claudio Dattolo, Vincenzo Miniello, Massimiliano Migliori, Cristina Grimaldi, Aldo Casani, Maurizio Borzumati, Stefano Cusinato, Alessandro Capitanini, Alessandro Quercia, Oliviero Filiberti, Lucia Dani
No abstract text is available yet for this article.
February 24, 2021: Journal of Nephrology
Valentina Iacono, Gianmarco Lombardi, Giancarlo Ottaviano, Giovanni Gambaro, Gianluigi Zaza
INTRODUCTION: Several studies have suggested that chronic kidney disease (CKD) may be associated with olfactory impairment. However, to date, the impact of renal replacement therapies has only been partly defined. METHODS: We tested the olfactory function of 235 participants [50 kidney transplant recipients (KT), 49 hemodialyzed patients (HD), 30 peritoneal dialysis patients (PD), 51 patients with CKD not on dialysis (ND-CKD) and 55 healthy subjects (HS)] by the Sniffin' Sticks test (Burghardt®, Wedel, Germany), including the sub-tests for the determination of odor threshold (T), odor discrimination (D), odor identification (I)...
February 24, 2021: Journal of Nephrology
Meng-Hsuan Hsieh, Ming-Jong Bair, Pei-Chien Tsai, Kuo-Chih Tseng, Ching-Chu Lo, Chi-Yi Chen, Hsing-Tao Kuo, Chao-Hung Hung, Hsueh-Chou Lai, Cheng-Yuan Peng, Jing-Houng Wang, Jyh-Jou Chen, Pei-Lun Lee, Rong-Nan Chien, Chi-Chieh Yang, Gin-Ho Lo, Jia-Horng Kao, Chun-Jen Liu, Chen-Hua Liu, Sheng-Lei Yan, Chun-Yen Lin, Wei-Wen Su, Cheng-Hsin Chu, Chih-Jen Chen, Shui-Yi Tung, Chi-Ming Tai, Chih-Wen Lin, Pin-Nan Cheng, Yen-Cheng Chiu, Chia-Chi Wang, Jin-Shiung Cheng, Wei-Lun Tsai, Han-Chieh Lin, Yi-Hsiang Huang, Ming-Lun Yeh, Chung-Feng Huang, Jee-Fu Huang, Chia-Yen Dai, Ming-Lung Yu, Wan-Long Chuang
BACKGROUND AND AIM: Chronic hepatitis C virus (HCV) infection is associated with impaired renal function. The aim of this study is to explore the risk of and factors associated with end stage renal diseases (ESRD) under maintenance dialysis among HCV patients after anti-HCV therapy. METHODS: A total of 12,696 HCV-infected patients with interferon-based therapy, including 9,679 (76.2%) achieving sustained virological response (SVR) were enrolled from 23 hospitals in Taiwan...
February 24, 2021: Journal of Gastroenterology and Hepatology
Anders J Haugen, Stein Hallan, Nina E Langberg, Dag Olav Dahle, Hege Pihlstrøm, Kåre I Birkeland, Anna V Reisæter, Karsten Midtvedt, Anders Hartmann, Hallvard Holdaas, Geir Mjøen
BACKGROUND: Previous reports suggest increased risk of hypertension and cardiovascular mortality after kidney donation. In this study we investigate occurrence of ischemic heart disease and cerebrovascular disease, diabetes and cancer in live kidney donors compared with healthy controls eligible for donation. METHODS: Different diagnoses were assessed in 1029 kidney donors and 16084 controls. The diagnoses at follow-up were self-reported for the controls and registered by a physician for the donors...
February 24, 2021: Nephrology, Dialysis, Transplantation
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