keyword
https://read.qxmd.com/read/38493378/designing-an-implementable-clinical-prediction-model-for-near-term-mortality-and-long-term-survival-in-patients-on-maintenance-hemodialysis
#1
JOURNAL ARTICLE
Benjamin A Goldstein, Chun Xu, Jonathan Wilson, Ricardo Henao, Patti L Ephraim, Daniel E Weiner, Tariq Shafi, Julia J Scialla
RATIONALE & OBJECTIVE: The life expectancy of patients treated with maintenance hemodialysis (MHD) is heterogeneous. Knowledge of life-expectancy may focus care decisions on near-term versus long-term goals. The current tools are limited and focus on near-term mortality. Here, we develop and assess potential utility for predicting near-term mortality and long-term survival on MHD. STUDY DESIGN: Predictive modeling study. SETTING & PARTICIPANTS: 42,351 patients contributing 997,381 patient months over 11 years, abstracted from the electronic health record (EHR) system of midsize, nonprofit dialysis providers...
February 21, 2024: American Journal of Kidney Diseases
https://read.qxmd.com/read/38493318/transplant-renal-artery-stenosis-a-case-report-and-literature-review
#2
JOURNAL ARTICLE
Nasser Simforoosh, Amirhossein Nayebzade, Meisam Ghaedi
Transplant renal artery stenosis is the most common vascular complication that turns out following kidney transplantation and can lead to graft dysfunction and even its loss. The present report, describes A patient with end-stage renal disease who underwent living related renal transplantation. He had oliguria and creatinine rise in the post-operative course but all doppler ultrasonography (DUS) during the 2 months post-operation for the renal graft showed a normal mean resistive index in the graft renal artery...
March 17, 2024: Urology Journal
https://read.qxmd.com/read/38493270/ykl-40-chitinase-3-like-protein-1-serum-levels-are-associated-with-abdominal-aortic-calcification-in-hemodialysis-patients
#3
JOURNAL ARTICLE
Shu-Hong Bi, Chunyan Su, La-Ta A, Yue Wang, Lian He, Ai-Hua Zhang
BACKGROUND: Vascular calcification (VC) is highly prevalent and predicts cardiovascular mortality in dialysis patients. The mechanisms are still unclear. Inflammation is a well-known inducer of VC. YKL-40 has been suggested as a novel biomarker of inflammation and has been demonstrated to be associated with cardiovascular mortality in hemodialysis patients. This study aims to evaluate the relationship between serum YKL-40 and VC in hemodialysis (HD) patients. METHODS: A total of 109 HD patients and 31 healthy controls were enrolled in the study from September 2014 to December 2014...
March 16, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38493124/the-moderating-role-of-social-support-in-the-relationship-between-death-anxiety-and-resilience-among-dialysis-patients
#4
JOURNAL ARTICLE
Zahra Shafiei Kisomi, Omid Taherkhani, Mina Mollaei, Hoda Esmaeily, Ghazaleh Shirkhanloo, Zahra Hosseinkhani, Mohammad Amerzadeh
BACKGROUND: Chronic Kidney Disease (CKD) who receive social support can cope with the challenges. Therefore, this study determined the moderating role of social support in the relationship between death anxiety and resilience among dialysis patients in Qazvin City. METHODS: This cross-sectional study used a descriptive-analytical approach on 347 dialysis patients in Qazvin City. The data collection tools included several questionnaires. The convenience sampling method was employed...
March 16, 2024: BMC Nephrology
https://read.qxmd.com/read/38493085/drug-utilization-in-patients-starting-haemodialysis-with-a-focus-on-cardiovascular-and-antidiabetic-medications-an-epidemiological-study-in-the-lazio-region-italy-2016-2020
#5
JOURNAL ARTICLE
Ursula Kirchmayer, Claudia Marino, Sandro Feriozzi, Carlo Massimetti, Micol Manzuoli, Laura Angelici, Anna Maria Bargagli, Silvia Cascini, Antonio Addis, Marina Davoli, Nera Agabiti
BACKGROUND: Entering dialysis is a critical moment in patients' healthcare journey, and little is known about drug therapy around it. A study funded by the Italian Medicines Agency offered the opportunity to leverage data from the Lazio Regional Dialysis and Transplant Registry (RRDTL) and perform an observational study on drug use patterns before and after initiating chronic dialysis. METHODS: Individuals initiating dialysis in 2016-2020 were identified from RRDTL, excluding patients with prior renal transplantation, stopping dialysis early, or dying within 12 months...
March 16, 2024: BMC Nephrology
https://read.qxmd.com/read/38493084/rate-and-reasons-for-peritoneal-dialysis-dropout-following-haemodialysis-to-peritoneal-dialysis-switch-a-systematic-review-and-meta-analysis
#6
JOURNAL ARTICLE
Xingge Sun, Clare McKeaveney, Joanne Shields, Chi Peng Chan, Matthew Henderson, Fiona Fitzell, Helen Noble, Stephen O'Neill
BACKGROUND: Patient experiences and survival outcomes can be influenced by the circumstances related to dialysis initiation and subsequent modality choices. This systematic review and meta-analysis aimed to explore the rate and reasons for peritoneal dialysis (PD) dropout following haemodialysis (HD) to PD switch. METHOD: This systematic review conducted searches in four databases, including Medline, PubMed, Embase, and Cochrane. The protocol was registered on PROSPERO (study ID: CRD42023405718)...
March 16, 2024: BMC Nephrology
https://read.qxmd.com/read/38492684/the-effect-of-niacinamide-supplementation-on-phosphate-concentrations-in-dutch-dialysis-patients-a-randomised-crossover-trial
#7
JOURNAL ARTICLE
Lara Schepers, Inez Jans, Gerda K Pot, Arend-Jan Smilde, Julia M Hofstra, Nicole M de Roos
OBJECTIVE: Hyperphosphatemia is a common complication in patients with kidney failure, despite the use of phosphate binders (PBs). Vitamin B3, either in the form of niacin or niacinamide (NAM), shows potential as "add-on" treatment to reduce serum phosphate concentrations in this population. NAM seems to lack many of the side-effects that are observed with niacin. The aim of this study was to investigate whether NAM is an effective and acceptable treatment in reducing serum phosphate concentrations in patients with kidney failure...
March 14, 2024: Journal of Renal Nutrition
https://read.qxmd.com/read/38492578/effects-of-rare-kidney-diseases-on-kidney-failure-a-longitudinal-analysis-of-the-uk-national-registry-of-rare-kidney-diseases-radar-cohort
#8
JOURNAL ARTICLE
Katie Wong, David Pitcher, Fiona Braddon, Lewis Downward, Retha Steenkamp, Nicholas Annear, Jonathan Barratt, Coralie Bingham, Constantina Chrysochou, Richard J Coward, David Game, Sian Griffin, Matt Hall, Sally Johnson, Durga Kanigicherla, Fiona Karet Frankl, David Kavanagh, Larissa Kerecuk, Eamonn R Maher, Shabbir Moochhala, Jenny Pinney, John A Sayer, Roslyn Simms, Smeeta Sinha, Shalabh Srivastava, Frederick W K Tam, Andrew Neil Turner, Stephen B Walsh, Aoife Waters, Patricia Wilson, Edwin Wong, Christopher Mark Taylor, Dorothea Nitsch, Moin Saleem, Detlef Bockenhauer, Kate Bramham, Daniel P Gale
BACKGROUND: Individuals with rare kidney diseases account for 5-10% of people with chronic kidney disease, but constitute more than 25% of patients receiving kidney replacement therapy. The National Registry of Rare Kidney Diseases (RaDaR) gathers longitudinal data from patients with these conditions, which we used to study disease progression and outcomes of death and kidney failure. METHODS: People aged 0-96 years living with 28 types of rare kidney diseases were recruited from 108 UK renal care facilities...
March 13, 2024: Lancet
https://read.qxmd.com/read/38492515/how-to-deal-with-renal-toxicities-from-immune-based-combination-treatments-in-metastatic-renal-cell-carcinoma-a-nephrological-consultation-for-oncologists
#9
REVIEW
Tucci Marcello, Cosmai Laura, Pirovano Marta, Campisi Ilaria, Re Sartò Giulia Vanessa, Porta Camillo, Gallieni Maurizio, Piergiorgio Messa
We are witnessing a revolution in the treatment of metastatic renal cell carcinoma (mRCC). Indeed, several immune-based combinations (ICI [immune checkpoint inhibitor] + ICI, or ICI + antiangiogenic agents) have been approved as first-line therapy for mRCC after demonstrating superior efficacy over the previous standard. Despite all the improvements made, safety remains a critical issue, adverse events (AEs) being the main reason for drug discontinuations or dose reductions, ultimately resulting in an increased risk of losing efficacy...
January 23, 2024: Cancer Treatment Reviews
https://read.qxmd.com/read/38492168/residents-satisfaction-and-suggestions-to-improve-nephrology-residency-in-italy-and-comparison-with-the-organization-in-other-european-countries
#10
JOURNAL ARTICLE
Adolfo Marco Perrotta, Silverio Rotondi, Maria Amicone, Irene Cirella, Rossella Siligato, Simone Fontana, Carmen Sivo, Anna Rita Vestri, Giovanni Gambaro, Giorgina Barbara Piccoli, Sandro Mazzaferro
BACKGROUND: In Italy, nephrology residency is available in twenty-one nephrology schools, each with its own strengths and weaknesses. The present study is aimed at exploring the residents' satisfaction with their training programs. METHODS: Between April 20th and May 19th, 2021, a questionnaire on residency satisfaction consisting of 49 items was sent to 586 residents and 175 recently certified specialists (qualified to practice as nephrologists in 2019 and 2020), with a response rate of 81% and 51%, respectively...
March 16, 2024: Journal of Nephrology
https://read.qxmd.com/read/38491448/uremic-toxins-mediate-kidney-diseases-the-role-of-aryl-hydrocarbon-receptor
#11
REVIEW
Hongyan Xie, Ninghao Yang, Chen Yu, Limin Lu
Aryl hydrocarbon receptor (AhR) was originally identified as an environmental sensor that responds to pollutants. Subsequent research has revealed that AhR recognizes multiple exogenous and endogenous molecules, including uremic toxins retained in the body due to the decline in renal function. Therefore, AhR is also considered to be a uremic toxin receptor. As a ligand-activated transcriptional factor, the activation of AhR is involved in cell differentiation and senescence, lipid metabolism and fibrogenesis...
March 15, 2024: Cellular & Molecular Biology Letters
https://read.qxmd.com/read/38491142/prognostic-impact-and-predictors-of-persistent-renal-dysfunction-in-acute-kidney-injury-after-percutaneous-coronary-intervention-for-acute-myocardial-infarction
#12
JOURNAL ARTICLE
Takuya Nakamura, Makoto Watanabe, Junichi Sugiura, Atsushi Kyodo, Saki Nobuta, Kazutaka Nogi, Yasuki Nakada, Satomi Ishihara, Yukihiro Hashimoto, Hitoshi Nakagawa, Tomoya Ueda, Ayako Seno, Taku Nishida, Kenji Onoue, Shungo Hikoso
This study aimed to evaluate the prognostic impact and predictors of persistent renal dysfunction in acute kidney injury (AKI) after an emergency percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI). A total of 877 patients who underwent emergency PCI for AMI were examined. AKI was defined as serum creatinine (SCr) ≥ 0.3 mg/dL or ≥ 50% from baseline within 48 h after PCI. Persistent AKI was defined as residual impairment of SCr ≥ 0...
March 15, 2024: Scientific Reports
https://read.qxmd.com/read/38490969/development-of-a-novel-risk-stratification-score-to-predict-30-day-mortality-in-cervical-trauma-patients-claad-score
#13
JOURNAL ARTICLE
Miguel A Cartagena-Reyes, Eric Solomon, Juan Silva Aponte, Aditya Joshi, Micheal Raad, Hamid Hassanzadeh, Amit Jain
STUDY DESIGN: Case control. OBJECTIVE: Traumatic cervical spine injuries are associated with a substantial risk of mortality. The aim of this study is to develop a novel mortality prediction model for patients with cervical trauma who require operative treatment. SUMMARY OF BACKGROUND DATA: Patients with cervical spine trauma have a high risk of postoperative complications and mortality. There are few reliable systems that can accurately predict mortality after surgery for cervical spine trauma, and those that do exist are typically not specific to cervical trauma...
March 11, 2024: Clinical Spine Surgery
https://read.qxmd.com/read/38490903/systemic-amyloidosis-and-kidney-transplantation-an-update
#14
REVIEW
Shankara K Anand, Vaishali Sanchorawala, Ashish Verma
Amyloidosis is a heterogeneous disorder characterized by abnormal protein aggregate deposition that often leads to kidney involvement and end-stage kidney disease. With advancements in diagnostic techniques and treatment options, the prevalence of patients with amyloidosis requiring chronic dialysis has increased. Kidney transplantation is a promising avenue for extending survival and enhancing quality of life in these patients. However, the complex and heterogeneous nature of amyloidosis presents challenges in determining optimal referral timing for transplantation and managing post-transplantation course...
March 14, 2024: Seminars in Nephrology
https://read.qxmd.com/read/38490516/role-of-peritoneal-equilibration-test-in-assessing-folate-transport-during-peritoneal-dialysis
#15
JOURNAL ARTICLE
Yu-Ling Lin, Yi-Che Lee, Chih-Chung Lee, Mei-Hsuan Wu
BACKGROUND: Low plasma folate levels have been reported in patients undergoing hemodialysis and peritoneal dialysis (PD) in clinical studies. However, folate transport has never been mentioned as a factor contributing to low plasma folate levels in patients undergoing PD. The peritoneal equilibrium test (PET) assesses the plasma creatinine level and glucose transport abilities. This study aimed to evaluate the association between plasma folate levels and folate transport during PD based on PET grades...
March 13, 2024: Journal of Renal Nutrition
https://read.qxmd.com/read/38490032/vaginal-peritoneum-fistula-through-pouch-of-douglas-during-peritoneal-dialysis-case-report-and-literature-review
#16
Francisco Aguilar-Espinosa, José Armando Álvarez-Maldonado, Luis Andrés Isaías-Velazquez, Jorge Alberto Martínez-Mejía, Oscar Daniel Mejía-Sierra, Erika Diana Barba-Jaramillo
INTRODUCTION: Peritoneal dialysis is the preferred approach for kidney replacement therapy. A peritoneal-vaginal fistula is a rare complication associated with peritoneal dialysis. CASE PRESENTATION: A 69-year-old woman with a history of type two diabetes and systemic arterial hypertension for twenty years is scheduled to undergo the surgical placement of a Tenckoff catheter to begin renal replacement therapy. After having thirty dialysis sessions, she was discharged to continue therapy at home...
March 11, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38489957/quantification-of-endogenous-angiotensin-1-10-1-9-1-8-1-7-and-1-5-in-human-plasma-using-micro-uhplc-ms-ms-outlining-the-importance-of-the-pre-analytics-for-reliable-results
#17
JOURNAL ARTICLE
Jonathan Maurer, Anke de Groot, Léon Martin, Eric Grouzmann, Grégoire Wuerzner, Philippe J Eugster
Angiotensin peptides (ANGs) play a central role in the renin-angiotensin-aldosterone system, rendering them interesting biomarkers associated with hypertension. Precise quantification of circulating ANGs holds the potential to assess the activity of angiotensin-converting enzyme (ACE), a key protease targeted by widely prescribed drugs, namely ACE inhibitors. This ability could pave the way for personalised medicine, offering insights into the prescription of inhibitors targeting either the proteases or the receptors within the system...
March 9, 2024: Journal of Pharmaceutical and Biomedical Analysis
https://read.qxmd.com/read/38489143/clinical-effect-of-roxadustat-vs-erythropoietin-in-non-dialysis-ckd-with-diabetes-a-single-center-propensity-score-matching-analysis
#18
JOURNAL ARTICLE
Chen Jin, Yan Ren, Minmin Wang, Xiao Hu, Yiwei Shang, Yiwen Li, Bin Zhu, Qiang He, Lina Shao
PURPOSE: Renal anemia is a common complication of chronic kidney disease. Currently, recombinant human erythropoietin and roxadustat are the main treatments. In China, diabetic kidney disease is the primary cause of chronic kidney disease. However, high-quality evidence on the efficacy of roxadustat in patients with non-dialysis-dependent chronic kidney disease and diabetes mellitus is scarce. This study aimed to assess the clinical effect of roxadustat in such patients. METHODS: Patients with non-dialysis-dependent anemia and diabetes mellitus who received roxadustat or recombinant human erythropoietin for ≥ 4 weeks were enrolled...
March 15, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38488947/dialysis-disequilibrium-syndrome-in-neurosurgery-literature-review-and-illustrative-case-example
#19
JOURNAL ARTICLE
Alexander R Evans, Xiaochun Zhao, Griffin L Ernst, Jorge Ortiz-Garcia, Ian F Dunn, John Burke
INTRODUCTION: The dialysis disequilibrium syndrome (DDS) is a complication in those undergoing dialysis for chronic kidney disease (CKD) or acute kidney injury (AKI), characterized by nonspecific symptoms that may progress to coma and death secondary to cerebral edema. This syndrome is associated with rapid change in electrolytes during dialysis with changes in intracranial pressure (ICP) and may have a higher incidence in the elderly neurosurgical patient population. METHODS: Literature review and illustrative case example...
March 15, 2024: GeroScience
https://read.qxmd.com/read/38488715/improving-ecmo-therapy-monitoring-oxygenator-functionality-and-identifying-key-indicators-factors-and-considerations-for-changeout
#20
JOURNAL ARTICLE
Salman Pervaiz Butt, Nabeel Razzaq, Yasir Saleem, Bill Cook, Salman Abdulaziz
INTRODUCTION: The optimal timing for extracorporeal membrane oxygenation (ECMO) circuit change-out is crucial for the successful management of patients with severe cardiopulmonary failure. This comprehensive review examines the various factors that influence the timing of oxygenator replacement in the ECMO circuit. By considering these factors, clinicians can make informed decisions to ensure timely and effective change-out, enhancing patient outcomes and optimizing the delivery of ECMO therapy...
March 2024: Journal of Extra-corporeal Technology
keyword
keyword
11
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.