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https://read.qxmd.com/read/30995453/intra-articular-botulinum-toxin-type-a-for-treatment-of-knee-osteoarthritis-clinical-trial
#1
Sharif Najafi, Ehsan Sanati, Mahsa Khademi, Fateme Abdorrazaghi, Reza Kazempoor Mofrad, Zahra Rezasoltani
In recent years, there is a growing interest in new medical applications of botulinum toxin, including pain control, osteoarthritis treatment, and wound healing. While clinical applications of botulinum toxin seem promising, existing evidence regarding the therapeutic effects is still inadequate. The aim was to assess the efficacy of a single injection of abobotulinumtoxin A into the knee joint cavity to reduce pain in elderly people. We carried out a single group clinical trial in a University Hospital. Thirty participants (24 women) more than 50 years of age with knee osteoarthritis were included...
April 14, 2019: Toxicon: Official Journal of the International Society on Toxinology
https://read.qxmd.com/read/30994717/the-radiological-exposure-from-the-perspective-of-the-interventional-cardiologist
#2
EDITORIAL
Pedro Beraldo de Andrade, André Labrunie
No abstract text is available yet for this article.
April 2019: Arquivos Brasileiros de Cardiologia
https://read.qxmd.com/read/30992300/personalized-detection-of-circulating-tumor-dna-antedates-breast-cancer-metastatic-recurrence
#3
Charles Coombes, Karen Page, Raheleh Salari, Robert K Hastings, Anne C Armstrong, Samreen Ahmed, Simak Ali, Susan Jane Cleator, Laura M Kenny, Justin Stebbing, Mark J Rutherford, Himanshu Sethi, Anna Rita Boydell, Ryan Swenerton, Daniel Fernandez-Garcia, Kelly Gleason, Katie Sarah Goddard, David S Guttery, Zoe Assaf, Hsin-Ta Wu, Prashanthi Natarajan, David A Moore, Lindsay Primrose, Scott Dashner, Antony S Tin, Mustafa Balcioglu, Ramya Srinivasa, Svetlana Shchegrova, Alexander G Olson, Dina Hafez, Paul Billings, Alexey Aleshin, Farah Rehman, Bradley Toghill, Allison H Hills, Maggie C Louie, Cheng-Ho Jimmy Lin, Bernhard G Zimmermann, Jaqueline A Shaw
PURPOSE: Up to 30% of breast cancer patients relapse after primary treatment. There are no sensitive and reliable tests to monitor these patients and detect distant metastases before overt recurrence. Here we demonstrate the use of personalized ctDNA profiling for detection of recurrence in breast cancer. METHODS: Forty-nine primary breast cancer patients were recruited following surgery and adjuvant therapy. Plasma samples (n=208) were collected every 6 months for up to 4 years...
April 16, 2019: Clinical Cancer Research
https://read.qxmd.com/read/30988860/successful-percutaneous-embolization-of-refractory-chylous-ascites-following-peritoneal-lymph-node-dissection
#4
Andrew Healey, Matthew Brice, Jennifer Healy, Charles Kitley
Chylous leaks are an uncommon complication in patients undergoing surgical procedures with the majority of cases responding to conservative therapies. Described is a case of a 23-year-old male who developed debilitating refractory chylous ascites as a complication after retroperitoneal lymph node dissection for testicular cancer. Prior to being evaluated by interventional radiology, he required weekly large-volume paracentesis in addition to standard conservative therapies. The patient underwent a single percutaneous treatment of a localized chylous leak involving a retroperitoneal lymphatic duct by utilizing a combined fenestration and embolization technique...
June 2019: Radiology Case Reports
https://read.qxmd.com/read/30987792/how-radiologists-can-benefit-from-direct-communication-with-patients
#5
REVIEW
Arvind Vijayasarathi, Richard Duszak
Effective communication is foundational to Radiology. Historically, radiologists have been considered "doctors' doctors," communicating primarily with referring physicians and other radiologists. Aside from interventional radiology and breast imaging, direct communication between radiologists and patients has typically been limited. In recent years, major radiology professional societies have launched initiatives aimed toward increasing direct radiologist and patient communication. These include the American College of Radiology's Imaging 3...
March 15, 2019: Current Problems in Diagnostic Radiology
https://read.qxmd.com/read/30982196/pathologic-discordance-to-clinical-management-decisions-suggests-overtreatment-in-pediatric-benign-breast-disease
#6
Maggie L Westfal, Numa P Perez, Ya-Ching Hung, David C Chang, Cassandra M Kelleher
PURPOSE: Breast masses in pediatric patients are often managed similarly to adult breast masses despite significant differences in pathology and natural history. Emerging evidence suggests that clinical observation is safe. The purpose of this study was to quantify the clinical appropriateness of the management of benign breast disease in pediatric patients. METHODS: A multi-institutional retrospective cohort study was completed between 1995 and 2017. Patients were included if they had benign breast disease and were 19 years old or younger...
April 13, 2019: Breast Cancer Research and Treatment
https://read.qxmd.com/read/30981070/retroperitoneal-space-occupying-lesion-with-displacement-of-the-inferior-vena-cava
#7
Stefan Niebisch, Holger Staab, Sebastian Ullrich, Karl-Titus Hoffmann, Osama Sabri, René Thieme, Katrin Schierle, Christian Wittekind, Ines Gockel
INTRODUCTION: The differential diagnosis and therapy of retroperitoneal masses suspicious for soft tissue tumors remains difficult and needs individual decisions as to the best management of patients. We report an unusual case of retroperitoneal schwannoma (RS). PRESENTATION OF CASE: We report on a 57-year-old female patient with a retroperitoneal space-occupying lesion with displacement, but no infiltration of surrounding vessels, especially the inferior vena cava...
March 30, 2019: International Journal of Surgery Case Reports
https://read.qxmd.com/read/30980796/double-balloon-enteroscopy-facilitated-cyanoacrylate-injection-endotherapy-of-small-bowel-varices-an-international-experience-from-2-european-tertiary-centers-with-videos
#8
Edward J Despott, Andrea May, Nikolaos Lazaridis, Erasmia Vlachou, Nikolaos Koukias, David Patch, Katie Planche, Yoshikazu Hayashi, Alberto Murino
BACKGROUND AND AIMS: Small-bowel varices (SBV) are an uncommon consequence of portal hypertension. Radiological intervention (RI) is usually considered for first-line management. When RI is not possible, management options become very limited. The aim of this study was to evaluate the usefulness of double-balloon enteroscopy (DBE)-facilitated cyanoacrylate-injection endotherapy of SBV. METHODS: This was a retrospective review of DBE-facilitated cyanoacrylate-injection endotherapy of SBV (December 2015 to October 2016)...
April 10, 2019: Gastrointestinal Endoscopy
https://read.qxmd.com/read/30976552/quantitative-features-can-predict-further-growth-of-persistent-pure-ground-glass-nodule
#9
Zhe Shi, Jiajun Deng, Yunlang She, Lei Zhang, Yijiu Ren, Weiyan Sun, Hang Su, Chenyang Dai, Gening Jiang, Xiwen Sun, Dong Xie, Chang Chen
Background: To evaluate whether quantitative features of persistent pure ground-glass nodules (PGGN) on the initial computed tomography (CT) scans can predict further nodule growth. Methods: This retrospective study included 59 patients with 101 PGGNs from 2011 to 2012, who received regular CT follow-up for lung nodule surveillance. Nineteen quantitative image features consisting of 8 volumetric and 11 histogram parameters were calculated to detect lung nodule growth...
February 2019: Quantitative Imaging in Medicine and Surgery
https://read.qxmd.com/read/30968662/how-to-evaluate-quality-of-life
#10
Silvia Porcu, Antonella Mandas
In medical terminology, it has become more and more common the use of the expression "Quality of Life" (QoL) to define a series of aspects that go beyond the traditional, clinical and "objective" evaluation of the medical intervention. The attention to QoL comes from the need to find tools that are able to reveal important aspects of the life of the patient that cannot be measured by a laboratory exam and/or a radiological procedure. The QoL is measured through multidimensional questionnaires on, at the very least, the domains of physical, psychological and social health...
March 29, 2019: Monaldi Archives for Chest Disease
https://read.qxmd.com/read/30967936/sequential-treatment-of-rupture-of-pseudoaneurysm-of-hepatic-artery-with-peritoneal-patch-and-radiological-embolization
#11
A Tashkandi, R Rhaiem, I Adlani, V Fossaert, D Sommacale, R Kianmanesh, T Piardi
Bleeding after pancreatico-duodenectomy (PD) is a serious complication with high rates of morbidity and mortality. Interventional radiology techniques' using embolization and/or stenting is the optimal management. In case of hemodynamic instability, surgical treatment is mandatory, but its mortality rate is considerable. Herein, we report the management of massive bleeding in a 52-year-old-male patient, 3 weeks after PD. The patient suffered severe hemorrhage with two cardiac arrests and surgical treatment was performed immediately after resuscitation...
April 2019: Journal of Surgical Case Reports
https://read.qxmd.com/read/30967909/intraperitoneal-rupture-of-the-hydatid-cyst-four-case-reports-and-literature-review
#12
Sami Akbulut, Fatih Ozdemir
BACKGROUND: Most patients with hydatid cysts are asymptomatic, and they are diagnosed incidentally during radiological evaluations performed for other reasons. However, some patients develop symptoms and complications due to cyst size, location, and the relationship between the cyst and adjacent structures. The most serious complications that can occur are rupture of the cysts into the biliary tract, vascular structures, hollow viscus, and peritoneal cavity. We aimed to describe the management of four cases of intraperitoneal rupture of hydatid cysts...
March 27, 2019: World Journal of Hepatology
https://read.qxmd.com/read/30963362/the-impact-of-simvastatin-intervention-on-the-healing-of-bone-soft-tissue-and-tmj-cartilage-in-dentistry-a-systematic-review-and-meta-analysis
#13
REVIEW
Swati Gupta, Massimo Del Fabbro, Jia Chang
The review aimed at assessing the osteopromotive potential as well as soft tissue and temporomandibular joint (TMJ) cartilage healing properties of simvastatin by summarizing its efficacy on the current dental treatment of periodontal bone and soft tissue defects, and temporomandibular joint (TMJ) arthritis from the available animals and human studies. An electronic search was performed on MEDLINE, Scopus, and Cochrane Central Register of Controlled Trials (CENTRAL) using a combination of keywords. A hand search was undertaken on seven oral surgery journals...
April 9, 2019: International Journal of Implant Dentistry
https://read.qxmd.com/read/30962927/are-interventional-radiology-and-allied-specialities-neglected-in-undergraduate-medical-education-a-systematic-review
#14
REVIEW
Elif Iliria Emin, Zeinab Ruhomauly, Iakovos Theodoulou, John Gerrard Hanrahan, Nikolaos Staikoglou, Marios Nicolaides, Narayanan Thulasidasan, Apostolos Papalois, Michail Sideris
Objectives: Minimally invasive interventional approaches are gaining wider acceptance with several specialities incorporating such principles. Awareness and understanding of interventional principles require efficacious education and training methodologies. We performed a systematic review to identify all available interventional speciality learning modules or training opportunities available for undergraduate medical students. We also propose a standardised framework for relevant modules...
April 2019: Annals of Medicine and Surgery
https://read.qxmd.com/read/30962831/safety-profile-and-efficacy-of-chemoembolization-with-doxorubicin-loaded-polyethylene-glycol-microspheres-in-patients-with-hepatocellular-carcinoma
#15
Aleksandar Gjoreski, Rozalinda Popova-Jovanovska, Irena Eftimovska-Rogac, Jusuf Vejseli
AIM: This study was designed as a preliminary investigation of safety and efficacy of LifePearl, polyethylene glycol microspheres loaded with doxorubicin for treatment of locally untreatable (i.e., unresectable and not suitable for local thermal ablation) hepatocellular carcinoma (HCC). MATERIAL AND METHODS: Patients with locally untreatable HCC (mono- or bilobar disease, ECOG performance status 0-1, Chilg-Pugh score < 11) were analysed for this single arm Unicenter retrospective study...
March 15, 2019: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/30962152/exogenous-lipoid-pneumonia-in-children-a-systematic-review
#16
REVIEW
Diana Marangu, Diane Gray, Aneesa Vanker, Marco Zampoli
OBJECTIVES: To describe the clinical-radiological-pathological characteristics and treatment outcomes of children with suspected exogenous lipoid pneumonia (ELP). DESIGN: Systematic review. We searched electronic databases and reference lists published between 1967 and 2018, restricted to non-accidental cases. RESULTS: Forty-four studies including 489 participants aged 1 day to 17 years from 13 countries were included. Cultural, medical, and behavioural rationale for oil-use was described...
January 20, 2019: Paediatric Respiratory Reviews
https://read.qxmd.com/read/30962125/epidemiology-of-inpatient-tibia-fractures-in-singapore-a-single-centre-experience
#17
Joshua Decruz, Rex Premchand Antony Rex, Suheal Ali Khan
PURPOSE: There are no previous epidemiological studies to represent the trends of tibia fractures in the urban setting. The purpose of our study was to provide unique epidemiological information on the incidence of tibia fractures requiring admission in the urban population of Singapore. METHODS: This is a retrospective review of clinical and radiological records encompassing three years period from 2012 to 2014 in a tertiary hospital in Northern Singapore, which covers an adult population of 550,000...
February 27, 2019: Chinese Journal of Traumatology
https://read.qxmd.com/read/30961569/osteoarthritis-a-systematic-review-of-long-term-safety-implications-for-osteoarthritis-of-the-knee
#18
Jonathon Charlesworth, Jane Fitzpatrick, Nirmala Kanthi Panagodage Perera, John Orchard
BACKGROUND: There is no cure for knee osteoarthritis (KOA) and typically patients live approximately 30-years with the disease. Most common medical treatments result in short-term palliation of symptoms with little consideration of long-term risk. This systematic review aims to appraise the current evidence for the long-term (≥12 months) safety of common treatments for knee osteoarthritis (KOA). METHODS: Cochrane Database of Systematic Reviews, Medline and PubMed were systematically searched from 1990 to July 2017, inclusive...
April 9, 2019: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/30956076/creating-a-transgender-inclusive-interventional-radiology-department
#19
REVIEW
Daniel L Kirkpatrick, Justin Stowell, Frances Grimstad, Elizabeth Brown, Shelby Fishback, Steven Lemons
Transgender (TG) people are individuals who experience an incongruity between their gender and the sex they were assigned at birth. Constituting 0.5%-2% of the population, TG individuals experience greater rates of discrimination, even in health care. Up to 23% of transgender people report having been refused basic medical care based on their gender identity, leading many to avoid seeking care. Familiarity of health care providers with TG issues and terminology has been shown to improve the experience of TG individuals in health care...
April 4, 2019: Journal of Vascular and Interventional Radiology: JVIR
https://read.qxmd.com/read/30955211/influences-of-operator-head-posture-and-protective-eyewear-on-eye-lens-doses-in-interventional-radiology-a-monte-carlo-study
#20
Li Mao, Tianyu Liu, Peter F Caracappa, Hui Lin, Yiming Gao, Lawrence T Dauer, X George Xu
PURPOSE: To quantify the effects of operator head posture and different types of protective eyewear on the eye lens dose to operators in interventional radiology (IR). METHODS: A deformable computational human phantom, RPI Adult Male, consisting of a high-resolution eye model, was used to simulate a radiologist who is performing an interventional radiology procedure. The radiologist phantom was deformed to a set of different head postures. Three different protective eyewear models were incorporated into the posture-deformed radiologist phantom...
April 7, 2019: Medical Physics
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