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JOURNAL ARTICLE
Markus Reichert, Marco Giurgiu, Elena Koch, Lena M Wieland, Sven Lautenbach, Andreas B Neubauer, Birte von Haaren-Mack, Renè Schilling, Irina Timm, Nanna Notthoff, Isabel Marzi, Holger Hill, Sarah Brüβler, Tobias Eckert, Janis Fiedler, Alexander Burchartz, Bastian Anedda, Kathrin Wunsch, Markus Gerber, Darko Jekauc, Alexander Woll, Genevieve F Dunton, Martina Kanning, Claudio R Nigg, Ulrich Ebner-Priemer, Yue Liao
Technological and digital progress benefits physical activity (PA) research. Here we compiled expert knowledge on how Ambulatory Assessment (AA) is utilized to advance PA research, i.e., we present results of the 2nd International CAPA Workshop 2019 "Physical Activity Assessment - State of the Science, Best Practices, Future Directions" where invited researchers with experience in PA assessment, evaluation, technology and application participated. First, we provide readers with the state of the AA science, then we give best practice recommendations on how to measure PA via AA and shed light on methodological frontiers, and we furthermore discuss future directions...
September 2020: Psychology of Sport and Exercise
#42
JOURNAL ARTICLE
Eva Susanne Capito, Stefan Lautenbacher, Jörg Wolstein, Claudia Horn-Hofmann
Background and aims Evidence for analgesic effects of oral alcohol consumption on heat pain has recently been documented in a placebo-controlled, randomized and double-blind design. We aimed at further investigating these effects and now set the focus on pain threshold and the ratings of supra-threshold pain to cover most of the pain range. Moreover, we now firstly evaluated sex differences in these effects. Methods We investigated 41 healthy participants (22 females) in a randomized, double-blind and placebo-controlled design and targeted two different moderate breath-alcohol levels of 0...
July 28, 2020: Scandinavian Journal of Pain
#43
JOURNAL ARTICLE
Steffie Bunk, Mónica Emch, Kathrin Koch, Stefan Lautenbacher, Sytse Zuidema, Miriam Kunz
Aging is known to affect nociceptive processing, e.g., the ability to inhibit pain. This study aims to investigate whether pain responses in older individuals are associated with prefrontal characteristics, namely (i) executive functioning performance and (ii) structural brain variations in the prefrontal cortex. Heat and pressure stimuli were applied to assess pressure pain sensitivity and endogenous pain inhibition in 46 healthy older individuals. Executive functioning performance was assessed in three domains (i...
July 24, 2020: Brain Sciences
#44
JOURNAL ARTICLE
Julia E Szymczak, Brandi M Muller, Nikitha Shankar Shakamuri, Keith W Hamilton, Jeffrey S Gerber, Maryrose Laguio-Vila, Ghinwa K Dumyati, Scott K Fridkin, Alice Y Guh, Sujan C Reddy, Ebbing Lautenbach
BACKGROUND: Fluoroquinolones (FQs) and extended-spectrum cephalosporins (ESCs) are associated with higher risk of Clostridioides difficile infection (CDI). Decreasing the unnecessary use of FQs and ESCs is a goal of antimicrobial stewardship. Understanding how prescribers perceive the risks and benefits of FQs and ESCs is needed. METHODS: We conducted interviews with clinicians from 4 hospitals. Interviews elicited respondent perceptions about the risk of ESCs, FQs, and CDI...
May 29, 2020: Infection Control and Hospital Epidemiology
#45
JOURNAL ARTICLE
I Adachi, P Ahlburg, H Aihara, N Akopov, A Aloisio, N Anh Ky, D M Asner, H Atmacan, T Aushev, V Aushev, T Aziz, V Babu, S Baehr, P Bambade, Sw Banerjee, V Bansal, M Barrett, J Baudot, J Becker, P K Behera, J V Bennett, E Bernieri, F U Bernlochner, M Bertemes, M Bessner, S Bettarini, F Bianchi, D Biswas, A Bozek, M Bračko, P Branchini, R A Briere, T E Browder, A Budano, L Burmistrov, S Bussino, M Campajola, L Cao, G Casarosa, C Cecchi, D Červenkov, M-C Chang, R Cheaib, V Chekelian, Y Q Chen, Y-T Chen, B G Cheon, K Chilikin, K Cho, S Cho, S-K Choi, S Choudhury, D Cinabro, L Corona, L M Cremaldi, S Cunliffe, T Czank, F Dattola, E De La Cruz-Burelo, G De Nardo, M De Nuccio, G De Pietro, R de Sangro, M Destefanis, S Dey, A De Yta-Hernandez, F Di Capua, Z Doležal, I Domínguez Jiménez, T V Dong, K Dort, D Dossett, S Dubey, S Duell, G Dujany, S Eidelman, M Eliachevitch, J E Fast, T Ferber, D Ferlewicz, G Finocchiaro, S Fiore, A Fodor, F Forti, B G Fulsom, E Ganiev, M Garcia-Hernandez, R Garg, V Gaur, A Gaz, A Gellrich, J Gemmler, T Geßler, R Giordano, A Giri, B Gobbo, R Godang, P Goldenzweig, B Golob, P Gomis, W Gradl, E Graziani, D Greenwald, Y Guan, C Hadjivasiliou, S Halder, T Hara, O Hartbrich, K Hayasaka, H Hayashii, C Hearty, M T Hedges, I Heredia de la Cruz, M Hernández Villanueva, A Hershenhorn, T Higuchi, E C Hill, M Hoek, C-L Hsu, Y Hu, T Iijima, K Inami, G Inguglia, J Irakkathil Jabbar, A Ishikawa, R Itoh, Y Iwasaki, W W Jacobs, D E Jaffe, E-J Jang, H B Jeon, S Jia, Y Jin, C Joo, K K Joo, J Kahn, H Kakuno, A B Kaliyar, J Kandra, G Karyan, Y Kato, T Kawasaki, B H Kim, C-H Kim, D Y Kim, K-H Kim, S-H Kim, Y K Kim, Y Kim, T D Kimmel, H Kindo, C Kleinwort, P Kodyš, T Koga, S Kohani, I Komarov, S Korpar, N Kovalchuk, T M G Kraetzschmar, P Križan, R Kroeger, P Krokovny, T Kuhr, J Kumar, M Kumar, R Kumar, K Kumara, S Kurz, A Kuzmin, Y-J Kwon, S Lacaprara, C La Licata, L Lanceri, J S Lange, K Lautenbach, I-S Lee, S C Lee, P Leitl, D Levit, L K Li, Y B Li, J Libby, K Lieret, L Li Gioi, Z Liptak, Q Y Liu, D Liventsev, S Longo, T Luo, Y Maeda, M Maggiora, E Manoni, S Marcello, C Marinas, A Martini, M Masuda, T Matsuda, K Matsuoka, D Matvienko, F Meggendorfer, J C Mei, F Meier, M Merola, F Metzner, M Milesi, C Miller, K Miyabayashi, H Miyake, R Mizuk, K Azmi, G B Mohanty, T Moon, T Morii, H-G Moser, F Mueller, F J Müller, Th Muller, G Muroyama, R Mussa, E Nakano, M Nakao, M Nayak, G Nazaryan, D Neverov, C Niebuhr, N K Nisar, S Nishida, K Nishimura, M Nishimura, B Oberhof, K Ogawa, Y Onishchuk, H Ono, Y Onuki, P Oskin, H Ozaki, P Pakhlov, G Pakhlova, A Paladino, A Panta, E Paoloni, H Park, B Paschen, A Passeri, A Pathak, S Paul, T K Pedlar, I Peruzzi, R Peschke, R Pestotnik, M Piccolo, L E Piilonen, V Popov, C Praz, E Prencipe, M T Prim, M V Purohit, P Rados, R Rasheed, S Reiter, M Remnev, P K Resmi, I Ripp-Baudot, M Ritter, G Rizzo, L B Rizzuto, S H Robertson, D Rodríguez Pérez, J M Roney, C Rosenfeld, A Rostomyan, N Rout, G Russo, D Sahoo, Y Sakai, S Sandilya, A Sangal, L Santelj, P Sartori, Y Sato, V Savinov, B Scavino, J Schueler, C Schwanda, R M Seddon, Y Seino, A Selce, K Senyo, C Sfienti, C P Shen, J-G Shiu, B Shwartz, A Sibidanov, F Simon, R J Sobie, A Soffer, A Sokolov, E Solovieva, S Spataro, B Spruck, M Starič, S Stefkova, Z S Stottler, R Stroili, J Strube, M Sumihama, T Sumiyoshi, D J Summers, S Y Suzuki, M Tabata, M Takizawa, U Tamponi, S Tanaka, K Tanida, N Taniguchi, P Taras, F Tenchini, E Torassa, K Trabelsi, T Tsuboyama, M Uchida, K Unger, Y Unno, S Uno, Y Ushiroda, S E Vahsen, R van Tonder, G S Varner, K E Varvell, A Vinokurova, L Vitale, A Vossen, M Wakai, H M Wakeling, W Wan Abdullah, C H Wang, M-Z Wang, A Warburton, M Watanabe, J Webb, S Wehle, C Wessel, J Wiechczynski, H Windel, E Won, B Yabsley, S Yamada, W Yan, S B Yang, H Ye, J H Yin, M Yonenaga, C Z Yuan, Y Yusa, L Zani, Z Zhang, V Zhilich, Q D Zhou, X Y Zhou, V I Zhukova
Theories beyond the standard model often predict the existence of an additional neutral boson, the Z^{'}. Using data collected by the Belle II experiment during 2018 at the SuperKEKB collider, we perform the first searches for the invisible decay of a Z^{'} in the process e^{+}e^{-}→μ^{+}μ^{-}Z^{'} and of a lepton-flavor-violating Z^{'} in e^{+}e^{-}→e^{±}μ^{∓}Z^{'}. We do not find any excess of events and set 90% credibility level upper limits on the cross sections of these processes. We translate the former, in the framework of an L_{μ}-L_{τ} theory, into upper limits on the Z^{'} coupling constant at the level of 5×10^{-2}-1 for M_{Z^{'}}≤6 GeV/c^{2}...
April 10, 2020: Physical Review Letters
#46
JOURNAL ARTICLE
Joe Amoah, Elizabeth A Stuart, Sara E Cosgrove, Anthony D Harris, Jennifer H Han, Ebbing Lautenbach, Pranita D Tamma
BACKGROUND: Propensity score methods are increasingly being used in the infectious diseases literature to estimate causal effects from observational data. However, there remains a general gap in understanding among clinicians on how to critically review observational studies that have incorporated these analytic techniques. METHODS: Using a cohort of 4967 unique patients with Enterobacterales bloodstream infections, we sought to answer the question "Does transitioning patients with gram-negative bloodstream infections from intravenous to oral therapy impact 30-day mortality?" We conducted separate analyses using traditional multivariable logistic regression, propensity score matching, propensity score inverse probability of treatment weighting, and propensity score stratification using this clinical question as a case study to guide the reader through (1) the pros and cons of each approach, (2) the general steps of each approach, and (3) the interpretation of the results of each approach...
December 3, 2020: Clinical Infectious Diseases
#47
REVIEW
Fran Balamuth, Elizabeth R Alpern, Mengyuan Kan, Maya Shumyatcher, Katie Hayes, Ebbing Lautenbach, Blanca E Himes
STUDY OBJECTIVE: Sepsis recognition is a clinical challenge in children. We aim to determine whether peripheral blood gene expression profiles are associated with pathogen type and sepsis severity in children with suspected sepsis. METHODS: This was a prospective pilot observational study in a tertiary pediatric emergency department with a convenience sample of children enrolled. Participants were older than 56 days and younger than 18 years, had suspected sepsis, and had not received broad-spectrum antibiotics in the previous 4 hours...
June 2020: Annals of Emergency Medicine
#48
JOURNAL ARTICLE
Laurel E Redding, Brendan J Kelly, Darko Stefanovski, John K Lautenbach, Pam Tolomeo, Leigh Cressman, Eli Gruber, Paige Meily, Ebbing Lautenbach
Background: Clostridioides difficile infection (CDI) is the leading cause of antibiotic-associated and health care-associated diarrhea in humans. Recurrent CDI (R-CDI) occurs in ~20%-30% of patients with CDI and results in increased morbidity, mortality, and hospital costs. Genomic analyses have shown overlap of C. difficile isolates from animals and people, suggesting that a zoonotic reservoir may contribute to recurrence. The objective of this study was to determine whether pet ownership is a risk factor for recurrence of CDI...
January 2020: Open Forum Infectious Diseases
#49
REVIEW
Markus Reichert, Urs Braun, Sven Lautenbach, Alexander Zipf, Ulrich Ebner-Priemer, Heike Tost, Andreas Meyer-Lindenberg
Rapid worldwide urbanization benefits humans in many aspects, but the prevalence of common psychiatric disorders is increased in urban populations. While the impact of city living and urban upbringing on mental health is well established, it remains elusive which of the multiple factors of urban living convey risk and resilience for mental disorders. For example, air pollutants, traffic noises and fragmented social networks are some of the highly interdependent and complex influences of city living suggested to be detrimental for mental health...
September 9, 2019: Current Opinion in Psychology
#50
JOURNAL ARTICLE
Margot W M de Waal, Annelore H van Dalen-Kok, Henrica C W de Vet, Lydia Gimenez-Llort, Ljubica Konstantinovic, Marina de Tommaso, Thomas Fischer, Albert Lukas, Miriam Kunz, Stefan Lautenbacher, Frank Lobbezoo, Brian E McGuire, Jenny T van der Steen, Wilco P Achterberg
BACKGROUND: Recognition of pain in people with dementia is challenging. Observational scales have been developed, but there is a need to harmonize and improve the assessment process. In EU initiative COST-Action TD1005, 36 promising items were selected from existing scales to be tested further. We aimed to study the observer agreement of each item, and to analyse the factor structure of the complete set. METHODS: One hundred and ninety older persons with dementia were recruited in four different countries (Italy, Serbia, Spain and The Netherlands) from different types of healthcare facilities...
February 2020: European Journal of Pain: EJP
#51
JOURNAL ARTICLE
Jennifer H Han, Zena Lapp, Frederic Bushman, Ebbing Lautenbach, Ellie J C Goldstein, Lisa Mattei, Casey E Hofstaedter, Dorothy Kim, Irving Nachamkin, Charles Garrigan, Tanya Jain, Warren Bilker, Hannah M Wolford, Rachel B Slayton, Jacqueleen Wise, Pam Tolomeo, Evan S Snitkin
Carbapenem-resistant Klebsiella pneumoniae (CRKP) is an antibiotic resistance threat of the highest priority. Given the limited treatment options for this multidrug-resistant organism (MDRO), there is an urgent need for targeted strategies to prevent transmission. Here, we applied whole-genome sequencing to a comprehensive collection of clinical isolates to reconstruct regional transmission pathways, and analyzed this transmission network in the context of statewide patient transfer data and patient-level clinical data to identify drivers of regional transmission...
August 26, 2019: Antimicrobial Agents and Chemotherapy
#52
JOURNAL ARTICLE
Franziska Lautenbach, Damian Jeraj, Jonna Loeffler, Lisa Musculus
High-fives are a phenomenon that is frequently observed in sports. However, investigations on effects of high-fives are missing. Therefore, the aim of the present study was to examine psychophysiological effects of high-fives. From an embodied cognition perspective, dynamic, upward movements compared to downward movements should activate positive concepts that are represented by psychological as well as physiological states. Thirty-four athletes performed high- and low-fives (dynamic movements) as opposed to high and low static postures (control conditions) in a double-blind, within-subject design...
September 2019: Applied Psychophysiology and Biofeedback
#53
MULTICENTER STUDY
Pranita D Tamma, Anna T Conley, Sara E Cosgrove, Anthony D Harris, Ebbing Lautenbach, Joe Amoah, Edina Avdic, Pam Tolomeo, Jacqueleen Wise, Sonia Subudhi, Jennifer H Han
IMPORTANCE: Conversion to oral therapy for Enterobacteriaceae bacteremia has the potential to improve the quality of life of patients by improving mobility, eliminating catheter-associated discomfort, decreasing the risk for noninfectious and infectious catheter-associated adverse events, and decreasing health care costs. OBJECTIVE: To compare the association of 30-day mortality with early oral step-down therapy vs continued parenteral therapy for the treatment of Enterobacteriaceae bloodstream infections...
March 1, 2019: JAMA Internal Medicine
#54
JOURNAL ARTICLE
Johanna Basten-Günther, Madelon Peters, Stefan Lautenbacher
A growing body of literature provides evidence of the health-promoting effects of optimism, including its protective role in acute and chronic pain. Optimists are characterized by positive expectations concerning the future. These positive outcome expectancies lead to more and longer goal-directed efforts and the use of approach coping strategies. No systematic review on the effects of optimism on the experience of pain has so far been conducted. A search in the databases PubMed, Web of Science and PsycInfo, and the scanning of reference lists identified 69 eligible studies...
December 20, 2018: Behavioral Medicine
#55
JOURNAL ARTICLE
Kevin J Downes, Julie C Fitzgerald, Emily Schriver, Craig L K Boge, Michael E Russo, Scott L Weiss, Fran Balamuth, Sherri E Kubis, Pam Tolomeo, Warren B Bilker, Jennifer H Han, Ebbing Lautenbach, Susan E Coffin, Jeffrey S Gerber
Background: Biomarkers can facilitate safe antibiotic discontinuation in critically ill patients without bacterial infection. Methods: We tested the ability of a biomarker-based algorithm to reduce excess antibiotic administration in patients with systemic inflammatory response syndrome (SIRS) without bacterial infections (uninfected) in our pediatric intensive care unit (PICU). The algorithm suggested that PICU clinicians stop antibiotics if (1) C-reactive protein <4 mg/dL and procalcitonin <1 ng/mL at SIRS onset and (2) no evidence of bacterial infection by exam/testing by 48 hours...
November 22, 2018: Journal of the Pediatric Infectious Diseases Society
#56
RANDOMIZED CONTROLLED TRIAL
Juliane Traxler, Marjolein M Hanssen, Stefan Lautenbacher, Fabian Ottawa, Madelon L Peters
BACKGROUND: Previous studies found evidence that dispositional optimism is related to lower pain sensitivity. Recent findings suggest that temporarily increasing optimism by means of imagining a positive future may also have pain-alleviating effects. OBJECTIVES: The present experiment was designed to investigate conditioned pain modulation (CPM) as a potential underlying mechanism of this pain-alleviating effect of induced optimism. METHODS: For this purpose, 45 healthy participants were randomized into an optimistic or neutral imagery condition...
January 2019: European Journal of Pain: EJP
#57
JOURNAL ARTICLE
Pranita D Tamma, Virginia M Pierce, Sara E Cosgrove, Ebbing Lautenbach, Anthony Harris, Divya Rayapati, Jennifer H Han
Background: In 2010, the Clinical Laboratory and Standards Institute recommended a 3-fold lowering of ceftriaxone breakpoints to 1 mcg/mL for Enterobacteriaceae . Supportive clinical data at the time were from fewer than 50 patients. We compared the clinical outcomes of adults with Enterobacteriaceae bloodstream infections treated with ceftriaxone compared with matched patients (with exact matching on ceftriaxone minimum inhibitory concentrations [MICs]) treated with extended-spectrum agents to determine if ceftriaxone breakpoints could be increased without negatively impacting patient outcomes...
June 2018: Open Forum Infectious Diseases
#58
JOURNAL ARTICLE
Brendan J Kelly, Ebbing Lautenbach, Irving Nachamkin, Susan E Coffin, Jeffrey S Gerber, Barry D Fuchs, Charles Garrigan, Xiaoyan Han, Warren B Bilker, Jacqueleen Wise, Pam Tolomeo, Jennifer H Han
OBJECTIVES: Sepsis is associated with high early and total in-hospital mortality. Despite recent revisions in the diagnostic criteria for sepsis that sought to improve predictive validity for mortality, it remains difficult to identify patients at greatest risk of death. We compared the utility of nine biomarkers to predict mortality in subjects with clinically suspected bacterial sepsis. DESIGN: Cohort study. SETTING: The medical and surgical ICUs at an academic medical center...
July 2018: Critical Care Medicine
#59
JOURNAL ARTICLE
Stefan Lautenbacher, Anna Lena Walz, Miriam Kunz
BACKGROUND: For patients with advanced dementia, pain diagnosis and assessment requires observations of pain-indicative behavior by others. One type of behavior that has been shown to be a promising candidate is the facial response to pain. To further test how pain-indicative facial responses are, we investigated the predictive power of observational facial descriptors to (i) predict the self-report of pain and (ii) to differentiate between non-painful and painful conditions. In addition, the expertise of the observers (nurses vs...
April 11, 2018: BMC Geriatrics
#60
JOURNAL ARTICLE
Darunee Chotiprasitakul, Jennifer H Han, Ebbing Lautenbach, Sara E Cosgrove, Anthony D Harris, Pranita D Tamma
No abstract text is available yet for this article.
July 18, 2018: Clinical Infectious Diseases
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