R Asero, A Arena, M Cervone, M Crivellaro, F Lodi Rizzini, R Longo, D Macchia, G Manzotti, P Minale, F Murzilli, B R Polillo, V Pravettoni, E Ridolo, E Savi, D Villalta, S Amato, G Mistrello
Background: The prevalence of IgE reactivity against genuine walnut and hazelnut allergens is poorly defined. Objective: The IgE response to walnut and hazelnut was investigated in Italian patients with primary allergy to these nuts. Methods: Sera from 36 patients allergic to hazelnut and/or walnut, not reactive to PR-10, profilin, and LTP, underwent immunoblot analysis with extracts of both nuts. Results: Most patients had a history of systemic symptoms following the ingestion of the offending food(s). Twelve patients were sensitized to both walnut and hazelnut, and 13 were sensitized to other nuts and seeds (cashew, peanut, sesame, pine nut, almond, Brazil nut, and pistachio)...
October 2013: European Annals of Allergy and Clinical Immunology