Erhan Okay, Marcos R Gonzalez, Joseph O Werenski, Alisha Sodhi, Korhan Ozkan, Marcus Brookes, Maniram Ragbir, Kenneth Rankin, Anand Tn Kumar, Santiago A Lozano-Calderon
BACKGROUND: Fluorescence-guided surgery (FGS) is a novel technique to successfully assess surgical margins intraoperatively. Investigation and adoption of this technique in orthopaedic oncology remains limited. METHODS: The PRISMA guidelines were followed for this manuscript. Our study was registered on PROSPERO (380520). Studies describing the use of FGS for resection of bone and soft tissue sarcomas (STS) on humans were included. Diagnostic performance metrics (sensitivity, specificity, positive predictive value [PPV], negative predictive value [NPV] and accuracy) and margin positivity rate were the outcomes assessed...
December 22, 2023: Surgical Oncology