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Sexual transmitted disease

Sarah E Kidd, Jeremy A Grey, Elizabeth A Torrone, Hillard S Weinstock
During 2013-2017, the national annual rate of reported primary and secondary (P&S) syphilis cases in the United States increased 72.7%, from 5.5 to 9.5 cases per 100,000 population (1). The highest rates of P&S syphilis are seen among gay, bisexual, and other men who have sex with men (collectively referred to as MSM) (2), and MSM continued to account for the majority of cases in 2017 (1). However, during 2013-2017, the P&S syphilis rate among women increased 155.6% (from 0.9 to 2.3 cases per 100,000 women), and the rate among all men increased 65...
February 15, 2019: MMWR. Morbidity and Mortality Weekly Report
Tomoko Udo
OBJECTIVES: To examine the associations between incarceration history and chronic medical conditions in a nationally representative sample of U.S. adults and whether risk for chronic medical conditions differ by sex and race among those with incarceration history. METHOD: The data were from the 2012-2013 National Survey of Alcohol and Related Conditions III (N = 36,133). Multiple logistic regression was used to compare odds of a self-reported diagnosis for 24 chronic medical conditions by incarceration history, as well as by sex and race within those with incarceration history...
March 2019: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
Paula K Braverman
Human papillomavirus (HPV), the most common sexually transmitted viral infection worldwide, is the causative agent for cervical cancer and attributed to anogenital cancers as well as oropharyngeal cancer. Three effective, safe, prophylactic HPV vaccines have been licensed, and studies have demonstrated decreases in HPV prevalence and HPV-related disease endpoints without evidence of waning protection to date. In the United States, only the 9-valent vaccine, which covers 90% of the cancers attributed to HPV in US registries, is available...
February 1, 2019: Pediatric Annals
Howa Yeung, Kevin M Luk, Suephy C Chen, Brian A Ginsberg, Kenneth A Katz
Lesbian, gay, bisexual, and transgender (LGBT) persons face important health issues relevant to dermatologists. Men who have sex with men (MSM) are at higher risk of certain infectious diseases, including HIV, syphilis and other sexually transmitted diseases (STDs), methicillin-resistant Staphylococcus aureus infections, and invasive meningococcal disease, and might be at higher risk of non-infectious conditions, including skin cancer. Recommendations for preventive health care, including screening for HIV and other STDs, sexual health-related vaccinations, and HIV pre-exposure prophylaxis, differ for MSM compared with non-MSM...
March 2019: Journal of the American Academy of Dermatology
Marisa Passos Silva, Marta Ponte, Eulália Pereira, Daniel Caeiro, Lino Santos, Vasco Ribeiro
No abstract text is available yet for this article.
January 2019: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
X Q Tuo, H Wang, Mahan Yeledan, Z L Zhang, Z Gong, T Tian, Z Chen, Hailili Gulisiya, J H Dai
Objective: To study the prevalence of rush poppers use among men who have sex with men (MSM) in Urumqi and to analyze the mediating effect of high-risk sexual behavior between the use of rush poppers and human papillomavirus (HPV) infection. Methods: From January to June 2018, 651 MSM were recruited through network and publicity. Data was collected by using online questionnaire and anal swab were collected from them for HPV genotyping. According to Baron and Kenny ' s criterion, multivariate logistic regression models was used to analyze the mediation effect of high-risks sexual behaviors (multiple sexual partners, anal intercourse condom use) between rush poppers use and HPV infection...
February 6, 2019: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
Esther Collantes-Fernández, Javier Moreno-Gonzalo, Roberto Sánchez-Sánchez, Ignacio García-Bocanegra, Pilar Horcajo, Luis M Ortega-Mora
Bovine trichomonosis is a sexually transmitted disease considered as an important cause of early reproductive failure in beef cattle. To investigate the occurrence of the infection in different Spanish beef cattle-producing areas, retrospective data from the SALUVET veterinary diagnostic laboratory (Veterinary Faculty, Madrid, Spain) derived from the analysis of samples from beef bulls that were routinely tested for Tritrichomonas foetus infection, were compiled from 2011 to 2015. In addition, a number of potential risk factors were assessed...
February 2, 2019: Theriogenology
River A Pugsley, Thomas A Peterman
BACKGROUND: Presumptive antibiotic treatment is common for suspected chlamydia (CT) and gonorrhea (GC) infections before laboratory confirmation to prevent complications, reduce loss-to-follow-up, and interrupt transmission. We assessed this practice in sexually transmitted disease (STD) and family planning clinics. METHODS: We performed a retrospective analysis of data from clinics in Virginia in 2016 using administrative data merged with electronic laboratory reporting data...
March 2019: Sexually Transmitted Diseases
Adriana B Almeida, Perla F Araújo, Francisco M Bernal, Ana de Cassia Rosa, Sebastião A Valente, Antonio R L Teixeira
American trypanosomiasis is transmitted to humans by triatomine bugs through the ingestion of contaminated food, by blood transfusions or accidently in hospitals and research laboratories. In addition, the Trypanosoma cruzi infection is transmitted congenitally from a chagasic mother to her offspring, but the male partner's contribution to in utero contamination is unknown. The findings of nests and clumps of amastigotes and of trypomastigotes in the theca cells of the ovary, in the goniablasts and in the lumen of seminiferous tubules suggest that T...
January 27, 2019: Journal of Visualized Experiments: JoVE
Fernando Saldaña, Ignacio Barradas
In this paper, we study general recovery functions and treatment in the dynamics of an <mml:math xmlns:mml=""> <mml:mrow> <mml:mi>S</mml:mi> <mml:mi>I</mml:mi> <mml:mi>S</mml:mi> </mml:mrow> </mml:math> model for sexually transmitted infections with nonzero partnership length. It is shown how partnership dynamics influences the predicted prevalence at the steady state and the basic reproduction number. Sobol's indices are used to evaluate the contribution of model parameters to the overall variance of <mml:math xmlns:mml="http://www...
2019: Infectious Disease Modelling
Maider Arando Lasagabaster, Luis Otero Guerra
Syphilis is an infectious disease caused by the spirochaete Treponema pallidum subsp. pallidum which is transmitted by sexual contact or vertical transmission during pregnancy. The incidence of syphilis has increased in the last years, mainly among men who have sex with men. Without treatment, the disease develops into different clinical stages, being able to present cardiovascular or irreversible neurological complications after a number of years. The disease is classified as early syphilis - primary, secondary and early latent syphilis (less than 12 months) - which is contagious, and as late syphilis - late latent and tertiary syphilis- which is rarely contagious...
February 6, 2019: Enfermedades Infecciosas y Microbiología Clínica
Xin Mao, Ronghua Zhao, Rongmei Yao, Shanshan Guo, Lei Bao, Yingjie Gao, Jing Sun, Yanyan Bao, Yujing Shi, Xiaolan Cui
Cervicitis is a common sexually transmitted disease. In recent years, the abuse of antibiotic in the treatment of cervicitis results in the emergence of antibiotic-resistant bacteria; alternative strategies are needed to be developed. In this research, we investigated the effects of Feilin Vaginal Gel (FVG), a Chinese herbal formula, on the treatment of cervicitis. Two cervicitis models were optimized using BALB/c mouse; one in vitro model was established in HeLa cells. In Chlamydia trachomatis -induced cervicitis model, the high level of bacterial loads, the inflammation in tissue, and the cytokines in serum could be observed...
2019: Evidence-based Complementary and Alternative Medicine: ECAM
Cheryl L Kovar, Susan Bynum
OBJECTIVE: To assess staff attitudes, knowledge, and current practices in billing third-party payers for sexually transmitted disease (STD) services in public health departments/districts. DESIGN AND SAMPLE: A cross-sectional, online survey was administered to staff at 60 urban and rural health departments/districts. Snowball sampling was used for greater representation. There were 311 staff responses from 56 agencies represented in the data analysis. Of the 311 responses, 106 were public health nurses and seven of the health directors had nursing backgrounds...
February 6, 2019: Public Health Nursing
Sidi Yang, Yannick Traore, Celine Jimenez, Emmanuel A Ho
C. trachomatis is the most common sexually transmitted bacterial infection in the world. Although the infection can be easily controlled by the use of antibiotics, several reports of clinical isolates that are resistant to antibiotics have prompted us to search for alternative strategies to manage this disease. In this paper, we developed a nanoparticle formulation (PDGFR-β siRNA-PEI-PLGA-PEG NP) that can simultaneously induce autophagy in human cells and knock down PDGFR-β gene expression, an important surface binding protein for C...
February 4, 2019: Scientific Reports
Zhengping Zhu, Hongjing Yan, Sushu Wu, Yuanyuan Xu, Wenjiong Xu, Li Liu, Xin Li, Fei Xu, Roger Detels
OBJECTIVE: To examine the trends of HIV prevalence, risk behaviours and HIV testing among men who have sex with men (MSM) in Nanjing. DESIGN: Five consecutive cross-sectional surveys. SETTING: Nanjing, China. PRIMARY AND SECONDARY OUTCOME MEASURES: HIV and syphilis prevalence, HIV testing rate and factors associated with HIV infection; demographic characteristics and behaviours. RESULTS: 649, 669, 577, 633, 503 MSM were recruited from 2013 to 2017...
January 30, 2019: BMJ Open
Shoshana B Levy, Jyothi Gunta, Peter Edemekong
This article discusses sexually transmitted infections (STI) screening and focuses on reportable STIs. This includes gonorrhea, chlamydia, syphilis, and human immunodeficiency virus. Hepatitis B and C, trichomonas, and herpes are covered as well. Recommendations are summarized from the various organizations that produce screening recommendations. These screening recommendations only apply to asymptomatic individuals. Once an individual has symptoms, testing becomes diagnostic. It is important to know the prevalence of STIs within your population...
March 2019: Primary Care
Kiros Tareke, Abaineh Munshea, Endalkachew Nibret
OBJECTIVE: The objective of this study was to investigate the seroprevalence and associated risk factors of syphilis among pregnant women attending antenatal care at Felege Hiwot Referral Hospital, northwest Ethiopia. RESULT: Of the total 384 screened women for syphilis, 10 (2.6%) were found to be seropositive for Treponema pallidum. The odds of infection were about ten times (COR = 9.77, p = 0.002) higher in divorced women than in married women. The likelihood of syphilis was almost three times higher among rural residents compared to urban residents (COR = 3...
January 31, 2019: BMC Research Notes
Siegbert Rieg, Susanne Usadel, Matthias Müller
The incidence of sexually transmitted infections like syphilis or gonorrhea is still rising, particularly in the high-risk population of men having sex with men (MSM). Neisseria gonorrhoeae is capable to develop resistance to all antibiotics previously or currently used for treatment. Dual antimicrobial therapy with ceftriaxone and azithromycin is considered the current empirical first-line therapy. Since 2011 ceftriaxone-resistant strains have emerged in many countries and in 2018 the first case with high-level resistance to azithromycin and resistance to ceftriaxone was documented in the UK, making the development of new antimicrobials against gonorrhea a public health priority...
February 2019: Deutsche Medizinische Wochenschrift
Samantha N Muellers, Juliana A Gonzalez, Abinash Kaur, Vital Sapojnikov, Annie Laurie Benzie, Dean G Brown, David W Parkin, Brian J Stockman
Trichomoniasis is caused by the parasitic protozoan Trichomonas vaginalis and is the most prevalent, nonviral sexually transmitted disease. The parasite has shown increasing resistance to the current 5-nitroimidazole therapies indicating the need for new therapies with different mechanisms. T. vaginalis is an obligate parasite that scavenges nucleosides from host cells and then uses salvage pathway enzymes to obtain the nucleobases. The adenosine/guanosine preferring nucleoside ribohydrolase was screened against a 2000-compound diversity fragment library using a 1 H NMR-based activity assay...
February 1, 2019: ACS Infectious Diseases
Shan Qiao, Eileen Yuk-Ha Tsang, Jeffrey S Wilkinson, Freddy Lipeleke, Xiaoming Li
Male sex workers (MSWs) in Zimbabwe are a vulnerable sub-group at risk of violence, abuse, and HIV infection. This qualitative study examines the practices of male sex workers and vulnerabilities to HIV infection based on interviews among 15 MSWs in Bulawayo. All the interviews were recorded, transcribed, and analyzed with the guidance of grounded theory. The transcripts were translated by the interviewer into English using NVivo 11.0 software for coding and analysis. The MSWs interviewed reported diverse backgrounds in sexual orientation and life situations, plus a variety of work settings, income levels and access to clients...
January 30, 2019: AIDS Care
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